Clinical Trials Sponsored by SigmaDrugs Research Ltd.

Total 781 results

Rayner Intraocular Lenses Limited
Visioncare Research Ltd.

Withdrawn

Clinical Investigation of the Modified Rayner Monofocal Aspheric 600C (With Axis Marks) Intraocular Lens

Cataract

United Kingdom
Encube Ethicals Pvt. Ltd.
CBCC Global Research

Completed

Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

Actinic Keratoses

United States
Integrative Skin Science and Research
Sytheon Ltd.

Completed

The Effects of Terminalia Chebula Fruit Extract on the Gut Microbiome and Skin Biophysical Properties

Human Microbiome

United States
Sichuan Kelun Pharmaceutical Research Institute...

Enrolling by invitation

A Study of KL590586 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

China
Cycle Pharmaceuticals Ltd.
FARMOVS Clinical Research Organisation

Completed

Bioequivalence Study of Two Oral Haloperidol Tablets Formulations in Healthy Subjects Under Fed Conditions

Bioequivalence

South Africa
Nature Cell Co. Ltd.
KCRN Research, LLC

Completed

A Phase 2 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis

Osteoarthritis, Knee

United States
Genuine Research Center, Egypt
Medochemie LTD Cyprus

Completed

A Bioequivalence Study of Glibenclamide From Glibesyn 5 mg Tablets (Medochemie LTD Cyprus) and Daonil 5 mg Tablets (Sanofi-Aventis Cyprus Ltd. )

Healthy

Egypt
Paion UK Ltd.
Premier Research Group plc

Completed

Multiple Dose Safety and Efficacy Study Evaluating CNS 7056 Versus Midazolam in Patients Undergoing Colonoscopy

Sedation

United States
Biotronik AG
CBCC-VIBGYOR Research Pvt. Ltd.

Suspended

Safety and Clinical Performance of a Sirolimus-eluting Absorbable Metal Scaffold (BIOSOLVE-India)

Coronary Artery Disease

India
SPD Development Company Limited
Illingworth Research Ltd

Completed

Project-0027. Lay User Usage Study

Pregnancy

United Kingdom
Raisio Group
Clinical Research Institute HUCH Ltd

Completed

Lipid-lowering Effect of a Plant Stanol Ester Supplement Product

Dyslipidemias | Hypercholesterolemia | Hyperlipidemias
Research in Real-Life Ltd
Aerocrine AB

Suspended

Exhaled Nitric Oxide in Asthma Management

Asthma

United Kingdom
Immune Targeting Systems Ltd
Hammersmith Medicines Research

Completed

A Study to Evaluate the Safety, Tolerability and Immunogenicity of a Universal Influenza A Vaccine

Influenza

United Kingdom
KAI Pharmaceuticals
Trident Clinical Research Pty Ltd

Completed

Safety and Efficacy Study of KAI-1678 to Treat Subjects With Postoperative Pain

Pain, Postoperative

New Zealand
KAI Pharmaceuticals
Trident Clinical Research Pty Ltd

Completed

Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Spinal Cord Injury

Spinal Cord Injury

Australia
KAI Pharmaceuticals
Trident Clinical Research Pty Ltd

Completed

Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia

Postherpetic Neuralgia

Australia
Technovalia, Pty Ltd
Chulalongkorn University; Southern Star Research Pty Ltd.; BioNet-Asia

Active, not recruiting

Immunogenicity and Safety of ChulaCov19 BNA159 and ChulaCov19 BNA159.2 Vaccines as a Booster Dose in Adults

COVID-19, SARS CoV 2 Infection

Australia
Medicines for Malaria Venture
Nucleus Network Ltd; Southern Star Research Pty Ltd.

Completed

MMV533 Plasmodium Falciparum Volunteer Infection Study

Malaria

Australia
Kaifeng Pharmaceutical (Group) Co., Ltd.
Beijing Furen Biomedical Research Institute Co., Ltd.

Unknown

A Study to Evaluate the Pharmacokinetics of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection

Hemophilia A

China
Benova (Tianjin) Innovative medicine Research Co...

Completed

Clinical Trial of Pivmecillinam Hydrochloride Tablets in the Treatment of Uncomplicated Urinary Tract Infection

Uncomplicated Urinary Tract Infection

China
Taiwan Sunpan Biotechnology Development Co., Ltd.
Virginia Contract Research Organization Co., Ltd.

Completed

To Determine the MTD and to Evaluate the Safety, Efficacy and PK Profiles of TSB-9-W1 in Pre-treated Patients With mCRC. (TSB-9-W1)

Metastatic Colorectal Cancer

Taiwan
Medicines for Malaria Venture
Nucleus Network Ltd; Southern Star Research Pty Ltd.

Completed

Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of Ruxolitinib With Artemether-lumefantrine

Malaria

Australia
Medicines for Malaria Venture
Nucleus Network Ltd; Southern Star Research Pty Ltd.

Completed

A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533.

Malaria

Australia
Meabco A/S
Meddoc; Norwegian University of Life Sciences; Meddoc Research Indonesia Ltd; Meddoc...

Completed

Dose-finding Study of BP-C1 in Patients With Stage IV Breast Cancer

Metastatic Breast Cancer | Stage IV Breast Cancer

Taiwan, Thailand, Indonesia
Pulmotect, Inc.
Imperial College Healthcare NHS Trust; VirTus Respiratory Research Ltd; MWB Consulting... and other collaborators

Completed

The Effect of Inhaled PUL-042 on Rhinovirus-induced Symptoms in Smokers With GOLD Stage 0 COPD

COPD

United Kingdom
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer

Triple Negative Breast Cancer

China
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Active, not recruiting

SKB264 Injection vs Investigator Selected Regimens to Treat Locally Advanced, Recurrent or Metastatic Triple-negative Breast Cancer

Triple Negative Breast Cancer

China
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Not yet recruiting

A Phase II/III Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD)

Neuromyelitis Optica Spectrum Disorders

China
Sichuan Kelun Pharmaceutical Research Institute...
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Recruiting

A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients

Non-small Cell Lung Cancer

China
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Recruiting

A Phase I Clinical Study of Recombinant Humanized Anti-CD20(B-lymphocyte Antigen CD20) Monoclonal Antibody Subcutaneous Injection in the Treatment of Primary Membranous Nephropathy

Primary Membranous Nephropathy

China
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Recruiting

Study of B013 and Nab-Paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer

Triple Negative Breast Cancer (TNBC)

China
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Recruiting

SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer

Triple-negative Breast Cancer and HR+/HER2- BC

China
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Active, not recruiting

KL-A167 Injection Combined With Cisplatin and Gemcitabine vs Placebo Combined With Cisplatin and Gemcitabine in the Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Recurrent or Metastatic

China
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Completed

KL-A167 Injection in Recurrent or Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Recurrent or Metastatic

China
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Completed

An Open, Multicenter Phase II Study to Evaluate the Safety and Efficacy of KL-A167 Injection in Relapsed or Refractory Classical Hodgkin's Lymphoma

Classical Hodgkin Lymphoma

China
National Health Research Institutes, Taiwan
Genovate Biotechnology Co., Ltd.,; Taiwan Biotech Co., Ltd.

Unknown

A Taiwan Isoflavone Multicenter Study (TIMS)

Osteopenia | Low Bone Density

Taiwan
Institute of Cancer Research, United Kingdom
Case45 Ltd

Not yet recruiting

Deployment and Clinical Evaluation of an AI-powered Digital Oncology Biomarker Tool to guidE Treatment in TNBC (AIDOBE)

Triple Negative Breast Cancer
Japan Breast Cancer Research Group
Eisai Co., Ltd.

Recruiting

A Study to Compare Eribulin Mesylate + Pertuzumab + Trastuzumab With Paclitaxel or Docetaxel + Pertuzumab + Trastuzumab

Breast Cancer

Japan
NovoBliss Research Pvt Ltd
Collagen Lifesciences Private Limited

Completed

A Proof of Science, Dose-Response Study to Evaluate the Safety, Efficacy of Different Dosages of Test Treatments

Healthy | Osteoarthritis, Knee | Brittle Nails | Mild to Moderate Acne | Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1 | Other Specified Diseases of Hair and Hair Follicles

India
University of Melbourne
Southern Star Research Pty Ltd.

Completed

Safety and Immune Response of Adjuvanted SARS-CoV-2 (COVID-19) Beta Variant RBD Recombinant Protein (DoCo-Pro-RBD-1 + MF59®) and mRNA (MIPSCo-mRNA-RBD-1) Vaccines in Healthy Adults

SARS-CoV-2

Australia
Danone Asia Pacific Holdings Pte, Ltd.
Nutricia Research

Completed

New Infant Formula Trial in Healthy Term Subjects on Growth, Body Composition, Tolerance and Safety (Venus)

Healthy

Singapore
PRG Science & Technology Co., Ltd.
Amarex Clinical Research

Completed

Phase I Study of Progerinin in Healthy Volunteers

Hutchinson-Gilford Progeria Syndrome | Werner Syndrome

United States
Johnson & Johnson Vision Care, Inc.
Visioncare Research Ltd.

Terminated

A Comparison of Two Daily Disposable Contact Lenses

Refractive Error | Myopia

United Kingdom
Eminence Clinical Research, Inc.
BrosMed Medical Co., Ltd

Completed

Artimes Pro Low Profile Dilatation Catheters for Pre-Dilatation in Patients With Symptomatic Ischemic Heart Disease

Coronary Artery Disease | Coronary Stenosis | Heart Disease, Ischemic

United States
Encube Ethicals Pvt. Ltd.
Novum Pharmaceutical Research Services

Completed

Therapeutic Equivalence of Diclofenac Sodium Gel 3% vs Solaraze ® in the Treatment of Actinic Keratosis

Actinic Keratoses

United States
Health Products Research and Development Lda.
Blueclinical, Ltd.

Terminated

Effectiveness and Tolerability of LabiaStick#01 in Subjects With Symptomatic Non-hypertrophic Chronic Vulvar Dermatoses

Chronic Disease of Skin

Portugal
Adom Advanced Optical Technologies Ltd.
Inflamax Research Incorporated

Completed

Evaluation of Dry Eye by Tear Film Imager in a Low Humidity Environmental Exposure Chamber (TFI-LH16) (TFI-LH16)

Dry Eye

Canada
Research in Real-Life Ltd
Napp Pharmaceuticals Limited

Completed

A Guideline Approach to Therapy Step-down Utilising Flutiform Change and Step-down

Asthma

United Kingdom
Chanan Schneider
Clinical Research Consultants, Inc.

Completed

A Prospective, First in Man Study to Evaluate the Safety and Performance of the NovaCross™ Micro-catheter

Chronic Total Occlusion of Coronary Artery

Israel
Abbott
Rundo International Pharmaceutical Research & Development Co.,Ltd.

Completed

A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic

Cardiovascular Diseases | Dyslipidemias | Hypertriglyceridemia

China

Clinical Trials Sponsored by SigmaDrugs Research Ltd.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Singapore

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations