Clinical Trials Sponsored by Simbex, LLC

Total 10802 results

Timber Pharmceuticals LLC

Completed

A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis

Congenital Ichthyosis

United States, Australia
Nakhia Impex LLC

Not yet recruiting

Clinical Efficacy and Safety of 35 kDa Hyaluronan Fragment (HA35) Injection in the Treatment of Skin Problems.

Skin Inflammation | Cosmetic Skin

Mongolia
Nakhia Impex LLC

Completed

35kDa Hyaluronan Fragment Treatment of Colorectal and Rectal Cancer

Cancer Pain

China
Nakhia Impex LLC

Completed

Local Injection for the Treatment of Chronic Wounds and Pain Caused by Chronic Wounds

Pain | Chronic Wound

China
Redx Pharma Plc
Simbec Research

Completed

A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers

Liver Diseases | Fibrosis | Kidney Diseases | Inflammation | Idiopathic Pulmonary Fibrosis | Non-alcoholic Steatohepatitis

United Kingdom
Redx Pharma Plc
Simbec Research

Recruiting

Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of RXC007 in Idiopathic Pulmonary Fibrosis

Fibrosis | IPF

Italy, Spain, United States, Belgium, United Kingdom, Austria, Czechia, Poland, Switzerland
Spero Therapeutics
Simbec Research; QPS Holdings LLC

Completed

Phase 1 Study to Evaluate DDI, PK, Safety, Tolerability of SPR741

Healthy Volunteers

United Kingdom
Simbec Research

Completed

A Study Comparing Three Formulations of Ibuprofen in Healthy Subjects

Healthy Volunteer Study

United Kingdom
AstraZeneca
Simbec Research

Completed

A Scintigraphy Study of PT010 in COPD Patients (RD708/34000)

Chronic Obstructive Pulmonary Disease

United Kingdom
Onxeo
Simbec Research

Completed

Phase 1 PK, Bioavailability, Safety Study of Clonidine MBT w Catapres in Healthy Volunteers

Healthy

United Kingdom
SCRI Development Innovations, LLC
Sirtex Medical

Completed

Safety Study of Regorafenib and SIR-Spheres® Microspheres Radioembolization in Patients With Refractory Metastatic Colorectal Cancer With Liver Metastases

Colorectal Neoplasms

United States
DiObex

Terminated

Open Label Safety & Pharmacodynamic Study 24Wk w/DIO-902 Combo w/Metformin & Atorvastatin in T2DM Patients

Type 2 Diabetes

Australia, United States, New Zealand
DiObex

Completed

A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Very Low Dose-Glucagon in Subjects With Type 1 Diabetes Mellitus

Type 1 Diabetes

United States
3M
Simbec Research

Completed

Two-period 21 Day Cross-over Study to Compare the Pharmacokinetics of Tiotropium From Two Inhalers

Healthy

United Kingdom
Simbec Research
Sensorion

Completed

A Study of SENS 401 in Healthy Subjects

Inner Ear Disease

United Kingdom
Diurnal Limited
Simbec Research

Completed

An Investigational Study of Hydrocortisone

Adrenal Insufficiency

United Kingdom
Prokarium Ltd
Simbec Research

Completed

Study to Evaluate the Safety, Tolerability and Immunogenicity of a Potential Enteric Fever Vaccine

Enteric Fever

United Kingdom
DiObex

Completed

A Phase 1/2a Study of the 2S,4R Enantiomer of Ketoconazole in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes

United States
DiObex

Terminated

A Phase 2b Study of DIO-902 or DIO-902 Placebo in Addition to Metformin and Atorvastatin or Atorvastatin Placebo for Type 2 Diabetes

Type 2 Diabetes

Australia, United States, New Zealand
Viramal Limited
Simbec Research

Recruiting

Study to Investigate the Pharmacokinetics & Safety Following One Application of 3 Different Doses 0.5,0.75,& 1.25 gm,a Transdermal Estradiol Cream (VML-0203), in Comparison to a Single Dose of EstroGel 1.25 gm to Healthy Post-menopausal Women.

Menopause

United Kingdom
Minervax ApS
Simbec Research

Completed

Group B Streptococcus Vaccine in Healthy Females (MVX0002)

Group B Strep Infection

United Kingdom
Spero Therapeutics
Simbec Research

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Diurnal Limited
Simbec Research

Completed

Comparison of Pharmacokinetics of Infacort® Versus Immediate-release Hydrocortisone

Healthy Subjects
Diurnal Limited
Simbec Research

Completed

An Open Label Study in Healthy Volunteers to Compare Chronocort® to Hydrocortisone

Congenital Adrenal Hyperplasia | Adrenal Insufficiency
Simbec Research
CN creative

Completed

A Study of Blood Levels of Nicotine Following an Electronic Cigarette

Nicotine Replacement Therapy
Sirtex Medical

Recruiting

Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry) (SIRtain)

Unresectable Hepatocellular Carcinoma (HCC) | Liver Metastases From Colorectal Cancer (mCRC)

Spain, United Kingdom, France
Sirtex Medical

Terminated

SIR-Spheres® for the Treatment of Unresectable Hepatocellular Carcinoma

Carcinoma, Hepatocellular | Hepatoma

United States
Sirtex Medical

Completed

FOLFOX6m Plus SIR-Spheres Microspheres vs FOLFOX6m Alone in Patients With Liver Mets From Primary Colorectal Cancer (FOXFIREGlobal)

Colorectal Cancer Metastatic

United States, France, Korea, Republic of, Australia, Israel, Singapore, Belgium, Taiwan, Spain, New Zealand, Portugal, Germany, Italy
Sirtex Medical

Completed

FOLFOX Plus SIR-SPHERES MICROSPHERES Versus FOLFOX Alone in Patients With Liver Mets From Primary Colorectal Cancer (SIRFLOX)

Colorectal Cancer | Liver Metastases | Colorectal Carcinoma

United States, Israel, Australia, Belgium, New Zealand, Spain, Germany, Switzerland, Italy, France, Poland
Diurnal Limited
Simbec Research

Completed

Effect of Slow Release Hydrocortisone on Fed & Fasting Volunteers; Immediate Release on Fasting Only

Healthy
Accure Therapeutics
Simbec Research

Completed

BN201 SAD MAD Study in Healthy Subjects

Optic Neuritis | Optic; Neuritis, With Demyelination

United Kingdom
Diurnal Limited
Simbec Research

Completed

A Two-part, Study to Compare the Pharmacokinetics and Dose Proportionality of up to 6 Chronocort Formulations

Congenital Adrenal Hyperplasia | Adrenal Insufficiency
Simbec Research
Sensorion SA

Completed

A Single Dose PK Study of SENS-218 in Healthy Volunteers

Inner Ear Diseases
Menarini Group
Simbec Research

Completed

Comparative Bioavailability of Dexketoprofen Trometamol Oral Solution vs Tablet Formulations

Acute Pain

United Kingdom
Genmedica Therapeutics S.L.
Simbec Research

Terminated

Multiple Ascending Dose Study of GMC-252-L-Lys Salt in Healthy Subjects and Type 2 Diabetics

Healthy | Type 2 Diabetes Mellitus

United Kingdom
Genmedica Therapeutics S.L.
Simbec Research

Terminated

Safety and Pharmacokinetics Study of a New Drug for Type 2 Diabetes

Healthy

United Kingdom
F2G Biotech GmbH
Simbec Research

Completed

F901318 Single Ascending Dose Study in Healthy Male Volunteers

Invasive Aspergillosis

United Kingdom
Atopix Therapeutics, Ltd.
Simbec Research

Completed

Evaluation of Metabolic Profile of OC000459

Asthma

United Kingdom
Sirtex Medical

Completed

SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma (SIRCCA)

Intrahepatic Cholangiocarcinoma

France, United Kingdom, Belgium, Australia, Spain, United States, Italy, Netherlands
Sirtex Medical

Completed

SIR-Spheres® Microspheres Versus Transarterial Chemoembolisation in Patients With Unresectable Hepatocellular Carcinoma (SIRTACE)

Hepatocellular Carcinoma

Germany, Spain
Sirtex Medical

Withdrawn

FOLFOX6 Plus Sir-Spheres Microspheres Plus Avastin in Patients With Nonresectable Liver Metastases From Colorectal Carcinoma (FAST)

Liver Metastases | Colorectal Carcinoma

United States
Nakhia Impex LLC
Mongolian National University of Medical Sciences

Completed

Freshly Manufactured 35kDa Hyaluronan Fragment HA35 for the Treatment of Chronic Wounds

Chronic Wounds

China
Minervax ApS
Simbec-Orion Group

Enrolling by invitation

A Follow up Study of Group B Streptococcus Vaccine (GBS-NN/NN2 Vaccine) in Healthy Volunteers

Group B Streptococcus Infection

United Kingdom
Atopix Therapeutics, Ltd.
Simbec Research

Completed

First in Man Evaluation of Single and Multiple Doses of Oral ATX2417

Allergy

United Kingdom
Artax Biopharma Inc
Simbec Research

Completed

Potential Food Effect And Repeated Dosing of AX-024.HCl In Healthy Subjects

Healthy

United Kingdom
Timber Pharmaceuticals Inc.

Active, not recruiting

The ASCEND Study: Evaluating TMB-001 in the Treatment of RXLI or ARCI Ichthyosis (ASCEND)

Ichthyosis

United States, Canada, Germany, France, Italy
Limbix Health, Inc.

Completed

A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19

Depression

United States
Limbix Health, Inc.

Completed

A Mobile and Virtual Reality Intervention for Adolescent Depression

Depression

United States
University of Delaware
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Mechanical Perturbation Training for ACL Injury Prevention

Anterior Cruciate Ligament Injury | ACL

United States
Nakhia Impex LLC
Mongolian National University of Medical Sciences

Completed

A Clinical Study of Pain and Discomfort Associated With Advanced Lung Cancer

Advanced Lung Cancer

Mongolia

Clinical Trials Sponsored by Simbex, LLC

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Iran

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Rare Diseases

Drug Interventions

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