Clinical Trials Sponsored by Solving Kids' Cancer

Total 254 results

University of Louisville
Solving Kids' Cancer

Completed

Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma

Neuroblastoma | Osteogenic Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma | Ewings Sarcoma

United States
Jennerex Biotherapeutics
Solving Kids' Cancer

Completed

Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients

Lymphoma | Neuroblastoma | Rhabdomyosarcoma | Wilm's Tumor | Ewing's Sarcoma

United States
The Hospital for Sick Children
Solving Kids' Cancer

Completed

Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS Tumours

Solid Tumors | Central Nervous System Tumors

Canada, United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Solving Kids' Cancer

Completed

Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).

Diffuse Intrinsic Pontine Glioma (DIPG)

United States
James Felker
National Cancer Institute (NCI); Solving Kids' Cancer

Recruiting

Immunotherapy for Recurrent Ependymomas in Children Using Tumor Antigen Peptides With Imiquimod

Ependymoma

United States
Istari Oncology, Inc.
Duke University; Solving Kids' Cancer; The Andrew McDonough B+ Foundation

Completed

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

Glioblastoma | Malignant Glioma | Gliosarcoma | Ependymoma | Medulloblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Atypical Teratoid/Rhabdoid Tumor of Brain | Pleomorphic Xanthoastrocytoma of Brain | Embryonal Tumor of Brain

United States
M.D. Anderson Cancer Center
Cancer Cures 4 Kids

Recruiting

Phase I Study of TH1 Dendritic Cell Immunotherapy for the Treatment of Cutaneous Angiosarcoma

Angiosarcoma

United States
Baylor College of Medicine
National Cancer Institute (NCI); The Methodist Hospital Research Institute; Center... and other collaborators

Active, not recruiting

3rd Generation GD-2 Chimeric Antigen Receptor and iCaspase Suicide Safety Switch, Neuroblastoma, GRAIN (GRAIN)

Neuroblastoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Solving Kids' Cancer; Ty Louis Campbell Foundation and other collaborators

Active, not recruiting

Phase I Study of APX005M in Pediatric CNS Tumors

Glioblastoma Multiforme | Medulloblastoma | High-grade Astrocytoma NOS | CNS Primary Tumor, Nos | Ependymoma, NOS | Diffuse Intrinsic Pontine Gliomas (DIPG)

United States
University Hospital Southampton NHS Foundation...
University College London Hospitals; University of Wisconsin, Madison; University... and other collaborators

Recruiting

Phase I Study of 131-I mIBG Followed by Nivolumab & Dinutuximab Beta Antibodies in Children With Relapsed/Refractory Neuroblastoma (MiniVan)

Neuroblastoma

United Kingdom, United States
Memorial Sloan Kettering Cancer Center
Xcovery Holding Company, LLC

Active, not recruiting

Treating Patients With Melanoma and ALK Alterations With Ensartinib

Melanoma

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy... and other collaborators

Completed

TAA-Specific CTLS for Solid Tumors (TACTASOM)

Rhabdomyosarcoma

United States
University of Wisconsin, Madison
National Cancer Institute (NCI); Solving Kids' Cancer; Wade's Army; Midwest Athletes... and other collaborators

Withdrawn

Treatment of Relapsed or Refractory Neuroblastoma and Osteosarcoma With Expanded Haploidentical NK Cells and Hu14.18-IL2

Osteosarcoma | Neuroblastoma | Recurrent Neuroblastoma | Relapsed Neuroblastoma

United States
Baylor College of Medicine
Cancer Cures for Kids

Recruiting

Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma (DECIST)

Pancreatic Cancer | Pancreatic Adenocarcinoma

United States
New Approaches to Neuroblastoma Therapy Consortium
Pfizer; University of Southern California; Cookies for Kids' Cancer; The Evan Foundation and other collaborators

Active, not recruiting

NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)

Neuroblastoma

Canada, United States, France, United Kingdom
Vejle Hospital
Danish Cancer Society; Design School Kolding

Active, not recruiting

Development of a Decision Aid to Facilitate Ovarian Cancer Patient's Choices Regarding Biomarker CA125

Ovarian Cancer

Denmark
St. Jude Children's Research Hospital
Cookies for Kids' Cancer

Terminated

Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States
Yunnan AIDS Care Center

Unknown

Safety and Efficacy of Raltegravir+TDF+3TC in HBV/HIV Co-infected Patients

HIV Infections | HBV Coinfection

China
AIDS Malignancy Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center

Not yet recruiting

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

HIV Infection | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent... and other conditions
Emory University
Cannonball Kids' Cancer Foundation; Hyundai Hope On Wheels

Recruiting

Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors (AflacST1502)

Cancer

United States
Dana-Farber Cancer Institute
Cookies for Kids' Cancer; Aileron Therapeutics, Inc.; TeamConnor Childhood Cancer...

Completed

Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer

Lymphoma | Leukemia | Solid Tumor | Brain Tumor

United States
St. Jude Children's Research Hospital
Cookies for Kids' Cancer; CURE Childhood Cancer, Inc.

Active, not recruiting

Therapy for Children With Advanced Stage Neuroblastoma

Neuroblastoma

United States
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART C)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART A)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies (HEM-iSMART D)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART B)

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic...

Netherlands
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Not yet recruiting

Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma

Kaposi Sarcoma | HIV-1-infection | AIDS-related Kaposi Sarcoma
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Not yet recruiting

Incidence of HPV Infection and HPV-Associated Disease in Screening Indian Men Who Have Sex With HIV-Positive Men

HIV Infection | Human Papillomavirus Infection | Human Papillomavirus-Related Carcinoma

United States, India
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Completed

Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV

HIV Infection | Anal Cancer | Human Papilloma Virus Infection

United States, Puerto Rico
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Withdrawn

Peripheral Stem Cell Transplantation Followed By Infusion of White Blood Cells in Treating Patients With AIDS-Related Lymphoma

Lymphoma
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Completed

SU5416 in Treating Patients With AIDS-Related Kaposi's Sarcoma

Sarcoma

United States
Baylor College of Medicine
Cancer Prevention Research Institute of Texas; Center for Cell and Gene Therapy... and other collaborators

Active, not recruiting

Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Patients With Pediatric Solid Tumors (GAP) (GAP)

Liver Cancer

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Not yet recruiting

A Study of Propranolol to Treat Kaposi Sarcoma

Kaposi Sarcoma

Uganda, Argentina, Kenya, Mexico, Malawi, Zimbabwe, Brazil, South Africa
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

HIV Infection | Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Lymphoma | Multicentric Castleman Disease | Plasmablastic Lymphoma | Kaposi Sarcoma | Recurrent Lymphoma | Anal Carcinoma | Recurrent Kaposi Sarcoma | Recurrent Plasmablastic Lymphoma | Transplant-Related Kaposi Sarcoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC

HIV Infections | Cancer | HPV-Related Malignancy | Anal Cancer | HIV-Associated Malignant Neoplasm | AIDS Related Lymphoma | AIDS-related Kaposi Sarcoma | AIDS-Related Malignancy

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

HIV Infection | Tobacco-Related Carcinoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Completed

Zidovudine Plus Interleukin-2 and Ganciclovir in Treating Patients With AIDS-Related Primary Central Nervous System Lymphoma

Lymphoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Completed

Infrared Coagulation in Preventing Anal Cancer in Patients With HIV Who Have Anal Neoplasia

Precancerous Condition | Anal Cancer

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Feasibility Study of Ocular Surface Squamous Neoplasia Surgical Excision in People Living With HIV in Sub-Saharan Africa

HPV | Ocular Surface Squamous Neoplasia

Uganda
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Trial of Ixazomib for Kaposi Sarcoma

Kaposi Sarcoma | Skin

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Completed

Chemotherapy Followed By Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory AIDS-Related Lymphoma

Lymphoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed By Antiviral Therapy and Interferon Alfa in Treating Patients With HTLV-1-Related Adult T-Cell Leukemia/Lymphoma

Lymphoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Withdrawn

Combination Chemotherapy Followed by Rituximab and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed or Refractory AIDS-Related Non-Hodgkin's Lymphoma

Anaplastic Large Cell Lymphoma | AIDS-related Lymphoma | Adult Non-Hodgkin's Lymphoma
St. Jude Children's Research Hospital
Assisi Foundation; Cookies for Kids' Cancer

Completed

Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood B-Lymphoblastic Lymphoma

United States
Hackensack Meridian Health
M.D. Anderson Cancer Center; Iscador AG, Arlesheim, Switzerland.; Tackle Kids... and other collaborators

Recruiting

Iscador® P (Mistletoe) Immunotherapy for Recurrent Osteogenic Sarcoma

Osteogenic Sarcoma Recurrent

United States
University of Birmingham
Regeneron Pharmaceuticals; Cancer Research UK; Fight Kids Cancer; ADC Therapeutics...

Not yet recruiting

A Global Study of Novel Agents in Paediatric and Adolescent Relapsed and Refractory B-cell Non-Hodgkin Lymphoma (Glo-BNHL)

B-cell Non Hodgkin Lymphoma
Aaron Diamond AIDS Research Center

Unknown

A Study of Tucaresol in HIV-Infected Patients Who Are Taking Other Anti-HIV Drugs

HIV Infections

United States
Aaron Diamond AIDS Research Center

Completed

Placebo-Controlled Trial of Safety and Efficacy of Thalidomide in Patients With Infections Due to Mycobacterium and/or HIV

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; Janssen... and other collaborators

Recruiting

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Plasmablastic Lymphoma | Ann Arbor Stage I Diffuse Large B-Cell Lymphoma | Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | Ann Arbor Stage III Diffuse Large B-Cell Lymphoma | Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma

United States
R.S. Djamin
Erasmus Medical Center; Amphia Hospital; Stichting Solong

Completed

Macrolide Maintenance Therapy in Chronic Obstructive Pulmonary Disease (COLUMBUS)

COPD

Netherlands

Clinical Trials Sponsored by Solving Kids' Cancer

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belarus

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations