Clinical Trials Sponsored by Spark Therapeutics
Total 7098 results
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Spark TherapeuticsActive, not recruitingConfirmed Biallelic RPE65 Mutation-associated Retinal DystrophyUnited States
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Spark TherapeuticsActive, not recruitingHemophilia AUnited States, Canada, Australia
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Spark TherapeuticsCompletedHemophilia AUnited States, Australia, Canada, Israel, Thailand
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Spark TherapeuticsActive, not recruitingInherited Retinal Dystrophy Due to RPE65 Mutations
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Spark TherapeuticsCompletedHematologic Diseases | Blood Coagulation Disorders, Inherited | Coagulation Protein Disorders | Hemorrhagic Disorders | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Gene Therapy | Blood Coagulation Disorder | Gene Transfer | Adeno-Associated Virus (AAV) | Factor VIII (FVIII) | Factor VIII (FVIII)... and other conditionsUnited States
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Spark TherapeuticsCompletedHematologic Diseases | Hemophilia A | Blood Coagulation Disorders, Inherited | Coagulation Protein Disorders | Hemorrhagic Disorders | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Blood Coagulation Disorder | Factor VIII DeficiencyUnited States, Australia, Thailand, Canada
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Spark TherapeuticsCompletedChoroideremia | CHM (Choroideremia) Gene MutationsUnited States
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Spark TherapeuticsActive, not recruitingLysosomal Storage Diseases | Glycogen Storage Disease Type II | Glycogen Storage Disease Type 2 | Pompe Disease (Late-onset) | Pompe Disease | LOPD | Acid Maltase DeficiencyUnited States, Canada, Netherlands, France, Denmark, Germany, Italy, United Kingdom
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Spark TherapeuticsActive, not recruitingLeber Congenital AmaurosisUnited States
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Spark TherapeuticsCompletedLysosomal Storage Diseases | Glycogen Storage Disease Type 2 | Pompe Disease (Late-onset) | Pompe Disease | LOPD | Acid Maltase DeficiencyUnited States, Italy, United Kingdom, Netherlands, France, Germany
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Spark TherapeuticsCompleted
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Spark Therapeutics, Inc.Recruiting
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Roswell Park Cancer InstituteCelldex TherapeuticsCompletedAcute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Refractory Anemia | Blasts 30 Percent or Less of Bone Marrow Nucleated CellsUnited States
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SPARK BiopharmaRecruiting
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SPARK BiopharmaCompletedPharmacokinetics | Pharmacodynamics | Safety Issues | TolerabilityKorea, Republic of
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Spark Therapeutics, Inc.Children's Hospital of Philadelphia; University of IowaActive, not recruitingLeber Congenital Amaurosis | Inherited Retinal Dystrophy Due to RPE65 MutationsUnited States
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Spark Neuro Inc.Recruiting
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Spark Biomedical, Inc.CompletedNovel Earpiece for Transcutaneous Auricular Neurostimulation (tAN) for Symptoms of Opioid WithdrawalOpioid-use Disorder | Opioid WithdrawalUnited States
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Spark Biomedical, Inc.CompletedOpioid-use Disorder | Opioid WithdrawalUnited States
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Roswell Park Cancer InstituteNational Cancer Institute (NCI); Nektar TherapeuticsCompletedRecurrent Small Cell Lung CarcinomaUnited States
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Ranok Therapeutics (Hangzhou) Co., Ltd.RecruitingAdvanced Solid Tumor | DLBCLUnited States
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PfizerRoswell Park Cancer Institute; South Texas Accelerated Research Therapeutics...CompletedAdvanced Malignant Solid TumorsUnited States
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Duke UniversityBlue Spark TechnologiesNot yet recruitingHematologic Malignancy
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Mayo ClinicSpark Neuro Inc.Enrolling by invitationAlzheimer Disease | Mild Cognitive Impairment | Dementia With Lewy Bodies | Normal Control APOE e4 Carriers and NoncarriersUnited States
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Mayo ClinicSpark Neuro Inc.Completed
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Stanford UniversitySPARK (Stanford University)Suspended
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Roswell Park Cancer InstituteNational Cancer Institute (NCI); Incyte Corporation; Celldex TherapeuticsCompletedFallopian Tube Carcinoma | Ovarian Carcinoma | Primary Peritoneal CarcinomaUnited States
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University of CincinnatiSpark Biomedical, Inc.Not yet recruitingOpioid Use Disorder | Posttraumatic Stress DisorderUnited States
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The Cleveland ClinicBlue Spark TechnologiesUnknownTemperature
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Spark Biomedical, Inc.Battelle Memorial InstituteNot yet recruitingCognitive Performance | Acute Stress ReactionUnited States
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Akebia TherapeuticsCyclerion TherapeuticsCompletedType 2 Diabetes Mellitus With Diabetic NephropathyUnited States
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Akebia TherapeuticsCyclerion TherapeuticsCompletedHeart Failure With Preserved Ejection FractionUnited States, Canada
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Five Liters, Inc.RecruitingHeavy Menstrual Bleeding | Von Willebrand Disease, Type 1United States
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CRISPR Therapeutics AGRecruitingClear Cell Renal Cell Carcinoma | Pancreatic Adenocarcinoma | Cervical Carcinoma | Malignant Pleural Mesothelioma | Esophageal CarcinomaUnited States
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CRISPR Therapeutics AGActive, not recruitingT Cell LymphomaUnited States, Australia, Canada
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CRISPR Therapeutics AGActive, not recruitingB-cell Lymphoma | Non-Hodgkin Lymphoma | B-cell Malignancy | Adult B Cell ALLUnited States, Spain, Canada, France, Germany, Australia
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Bacainn Therapeutics, Inc.CompletedHealthy VolunteersUnited States
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Celsus Therapeutics PLCTerminatedAtopic DermatitisIsrael
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Eikon TherapeuticsImpact Therapeutics, Inc.RecruitingAdvanced Solid TumorAustralia, United States
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CRISPR Therapeutics AGActive, not recruitingRenal Cell CarcinomaUnited States, Australia, Canada, Netherlands
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APRINOIA Therapeutics, LLCActive, not recruitingAlzheimer Disease | Tauopathies | Healthy VolunteersUnited States
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CRISPR Therapeutics AGRecruitingFollicular Lymphoma | B-cell Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Non-Hodgkin Lymphoma | B-cell Malignancy | Large B-cell Lymphoma | Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)United States
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CRISPR Therapeutics AGEnrolling by invitationHematologic Malignancy | Solid MalignancyUnited States, Australia
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CRISPR Therapeutics AGActive, not recruitingMultiple MyelomaUnited States, Spain, Australia, Canada
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APRINOIA Therapeutics, LLCActive, not recruitingHealthy Volunteers | Alzheimer's Disease | Mild Cognitive Impairment Due to Alzheimer's DiseaseUnited States
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Spark TherapeuticsChildren's Hospital of Philadelphia; Royal Prince Alfred Hospital, Sydney,... and other collaboratorsCompleted
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Spark Biomedical, Inc.Hazelden Betty Ford FoundationEnrolling by invitationOpioid Use Disorder | RelapseUnited States
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Medical Park AGUnknownStroke | Transcranial Direct Current Stimulation | Speech Therapy | Aphasia, GlobalGermany
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Roswell Park Cancer InstituteNational Cancer Institute (NCI); Merck Sharp & Dohme LLC; Celldex TherapeuticsRecruitingRecurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Serous Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Platinum-Sensitive Ovarian Carcinoma | Recurrent Fallopian... and other conditionsUnited States
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CRISPR Therapeutics AGViaCyteRecruitingGlucose Metabolism Disorders | Immune System Diseases | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1 | Metabolic DiseaseCanada