Clinical Trials Sponsored by Therapeutics Research Centre

Total 11061 results

Fred Hutchinson Cancer Center
ADC Therapeutics

Withdrawn

Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Recurrent High... and other conditions

United States
M.D. Anderson Cancer Center
Direct Therapeutics

Completed

Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas

Glioma | Brain Neoplasms

United States
Meir Medical Center
SpotOn Therapeutics Ltd.

Completed

Study to Assess the Efficacy and Safety of SpotOn Specs™ for the Treatment of Chronic Dizziness

Chronic Dizziness

Israel
M.D. Anderson Cancer Center
BreakThrough Therapeutics

Completed

Synthetic Vaccine in Patients With Chronic Myeloid Leukemia and Minimal Residual Disease

Chronic Myeloid Leukemia | Minimal Residual Disease

United States
M.D. Anderson Cancer Center
vTv Therapeutics

Withdrawn

TTP607 in Refractory Solid Malignancies

Lymphoma | Advanced Cancers
Introgen Therapeutics
M.D. Anderson Cancer Center

Unknown

Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma

Neoplasm Metastasis | Malignant Melanoma

United States
Help Therapeutics
Central South University

Recruiting

Allogeneic iPSC-derived Cardiomyocyte Therapy in Patients With Worsening Ischemic Heart Failure

Chronic Heart Failure | Ischemic Heart Failure

China
Radboud University Medical Center
Endotools Therapeutics

Not yet recruiting

The GATE Study: Endoscopic Sutured Gastroplasty in Type 2 Diabetic, Obese Patients Using the Endomina Device (GATE)

Obesity | Diabete Type 2
AKARI Therapeutics
Radboud University Medical Center

Completed

Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH)

Paroxysmal Nocturnal Haemoglobinuria (PNH)

Netherlands
Fox Chase Cancer Center
WindMIL Therapeutics

Withdrawn

Feasibility Study on Expandion of MILs From NSCLC and SCLC Patients and Infusion With Pembrolizumab

NSCLC | SCLC
Bronx VA Medical Center
Chelsea Therapeutics

Completed

A Dose Titration of Droxidopa in Patients With Spinal Cord Injury

Hypotension | Spinal Cord Injury

United States
M.D. Anderson Cancer Center
Alaunos Therapeutics

Completed

Phase I Trial of ZIO-101 in Patients With Solid Tumors

Solid Tumors

United States
M.D. Anderson Cancer Center
Elevar Therapeutics

Not yet recruiting

A Phase II Study of Rivoceranib for Patients With Recurrent or Metastatic Olfactory Neuroblastoma

Metastatic Olfactory Neuroblastoma | Recurrent Olfactory Neuroblastoma

United States
M.D. Anderson Cancer Center
Mirati Therapeutics

Recruiting

Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer

Colorectal Cancer | Colon Cancer

United States
M.D. Anderson Cancer Center
Nektar Therapeutics

Recruiting

REStoring lymphoCytes Using NKTR-255* After chemoradiothErapy in Solid Tumors (RESCUE)

Lung Cancer

United States
Fred Hutchinson Cancer Center
Nektar Therapeutics

Recruiting

NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Recurrent Grade 3b Follicular Lymphoma | Refractory Grade 3b Follicular... and other conditions

United States
Tufts Medical Center
Partner Therapeutics, Inc.

Recruiting

A Study of Sargramostim Plus Pembrolizumab With or Without Pemetrexed in Patients With Advance Non-small Cell Lung Cancer After Completion of Chemoimmunotherapy

Advanced Lung Non-Small Cell Carcinoma | Non-Small Cell Carcinoma of Lung, TNM Stage 4

United States
Coeptis Therapeutics
Fred Hutchinson Cancer Center

Completed

Allogeneic Natural Killer (NK) Cell Therapy in Subjects Hospitalized for COVID-19

COVID-19 Pneumonia

United States
Cedars-Sinai Medical Center
CV Therapeutics

Completed

Microvascular Coronary Disease In Women: Impact Of Ranolazine

Myocardial Ischemia

United States
Sheba Medical Center
Karyopharm Therapeutics Inc

Unknown

Selinexor Combined With Standard Chemoradiation as Neoadjuvant Treatment in Locally Advanced Rectal Cancer

Rectal Neoplasms

Israel
1st Allergy & Clinical Research Center

Completed

Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens

Atopic Dermatitis

United States
McGill University Health Centre/Research Institute...
Université de Montréal; Argos Therapeutics

Completed

A Pilot Study to Investigate the Safety and Immunologic Activity AGS-004 an Autologous HIV Immunotherapeutic Agent.

Acquired Immunodeficiency Syndrome | HIV Seropositivity

Canada
Ottawa Hospital Research Institute
Knight Therapeutics (USA) Inc

Recruiting

Dose Escalation For INtraprostatic LEsions (DEFINE)

Prostatic Neoplasms

Canada
Calm Water Therapeutics LLC
Andover Research Eye Institute

Completed

Evaluation of the Tolerability and Efficacy of CWT-f-002 Lubricant Eye Drops

Dry Eye Disease

United States
Stanford University
Epidermolysis Bullosa Research Partnership; Menlo Therapeutics

Completed

A Neurokinin-1 Receptor Antagonist for the Treatment of Pruritus in Patients With Epidermolysis Bullosa

Epidermolysis Bullosa

United States
GSO Global Clinical Research BV
Karyopharm Therapeutics Inc

Terminated

Phase 1 Trial To Evaluate mFOLFOX6 With Selinexor In Patients With Metastatic Colorectal Cancer (SENTINEL)

Colorectal Neoplasm

Germany, Belgium
GSO Global Clinical Research BV
Karyopharm Therapeutics Inc

Completed

A Phase II Study of Selinexor Plus Cytarabine and Idarubicin in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (Relapsed/Refractory)

Germany
St. Jude Children's Research Hospital
Karyopharm Therapeutics Inc

Completed

Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Mixed Phenotype Acute Leukemia (MPAL)

United States
Cancer Therapeutics Research Group
National Cancer Institute (NCI)

Completed

Fenretinide In Treating Patients With Advanced or Metastatic Hormone-Refractory Prostate Cancer

Prostate Cancer

Australia, Singapore, Hong Kong
Chroma Therapeutics
Institute of Cancer Research, United Kingdom

Completed

Safety Study to Evaluate CHR-2797 in Patients With Advanced Tumours

Advanced Solid Tumors
Unilever R&D
Lambda Therapeutic Research Ltd.

Completed

Exploratory Study of Efficacy on Selected Natural Extracts Reducing Post Prandial Blood Glucose Response

Blood Glucose

India
Unilever R&D
Lambda Therapeutic Research Ltd.

Completed

Dose Response Study of a Natural Extract for Reducing Post Prandial Blood Glucose

Blood Glucose

India
St. Jude Children's Research Hospital
Kazia Therapeutics Limited

Completed

Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

Brain and Central Nervous System Tumors

United States
The Lymphoma Academic Research Organisation
Karyopharm Therapeutics Inc

Completed

A Phase Ib Study of Oral Selinexor in Adult Patients With Relapsed/Refractory B-cell Lymphoma Receiving R-DHAOx or R-GDP (SELINDA)

B-cell Lymphoma

Belgium, France
Ayana Pharma Ltd.,
Lambda Therapeutic Research Ltd.

Completed

A Study of Doxorubicin Hydrochloride Liposome Injection in Subjects With Ovarian Cancer.

Ovarian Cancer Recurrent

India
St. Jude Children's Research Hospital
SpringWorks Therapeutics, Inc.

Recruiting

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

Low-Grade Glioma | Recurrent Low-Grade Glioma | Progressive Low-Grade Glioma

United States
St. Jude Children's Research Hospital
Karyopharm Therapeutics Inc

Terminated

Selinexor in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)

United States
Cancer Therapeutics Research Group
National Cancer Institute (NCI)

Completed

3-AP and Gemcitabine as Second-Line Therapy in Treating Patients With Stage III or Stage IV Recurrent Non-Small Cell Lung Cancer

Lung Cancer

Australia, Singapore, Hong Kong, Korea, Republic of
Cancer Therapeutics Research Group
National Cancer Institute (NCI)

Completed

Irofulven in Treating Patients With Recurrent or Metastatic Gastric Cancer

Gastric Cancer

Australia, Singapore, Hong Kong, Korea, Republic of
Arana Therapeutics Ltd
Trident Clinical Research Pty Ltd

Completed

Dose Optimisation Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate

Rheumatoid Arthritis

Sri Lanka
Sarepta Therapeutics, Inc.
Baim Institute for Clinical Research

Completed

Safety and Efficacy of RESTEN-MP When Used in Conjunction With a Bare Metal Stent in Coronary Arteries

Coronary Artery Disease | Coronary Restenosis

Germany
Intas Pharmaceuticals, Ltd.
Lambda Therapeutic Research Ltd.

Completed

Comparative, Pharmacokinetic and Pharmacodynamic Study of Subcutaneous Injections of INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects.

Pharmacokinetic Bioequivalence Study in Human Healthy Volunteers

India
Intas Pharmaceuticals, Ltd.
Lambda Therapeutic Research Ltd.

Completed

Comparative Immunogenicity Study of Multiple Doses of Proposed Pegfilgrastim Biosimilar, INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects.

Healthy Volunteers | Immunogenicity

India
Fonterra Research Centre

Completed

Effects of a Probiotic on Aspects of Mental Wellness

Mental Health Wellness

United States
Research Centre BIOFORM

Unknown

Intra-articular Polyacrylamide Hydrogel in Knee Osteoarthritis

Osteoarthritis

Russian Federation
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Alaunos Therapeutics; National Center for Research...

Recruiting

Long-Term Follow-Up of Recipient of Gene Transfer Research

Retroviridae Infections | Cancer

United States
Global Coalition for Adaptive Research
Bayer; Kazia Therapeutics Limited; Biohaven Pharmaceuticals, Inc.; Kintara Therapeutics... and other collaborators

Recruiting

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma (GBM AGILE)

Glioblastoma

United States, France, Germany, Canada, Australia, Switzerland
M.D. Anderson Cancer Center
Mirati Therapeutics Inc.

Recruiting

Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers

Advanced Solid Tumor | Non-small Cell Lung Cancers

United States
M.D. Anderson Cancer Center
Blue Earth Therapeutics

Recruiting

NeoAdjuvant Theranostic Lutetium Study: The Nautilus Trial

Prostate Cancer

United States
M.D. Anderson Cancer Center
Tvardi Therapeutics, Inc

Not yet recruiting

Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Squamous Cell Carcinoma

Clinical Trials Sponsored by Therapeutics Research Centre

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