Clinical Trials Sponsored by Trio Medicines Ltd.

Total 1075 results

Trio Medicines Ltd.

Completed

Effect of Netazepide on Omeprazole-induced Changes in Chromogranin A and Gastrin

Dyspepsia | ECL-cell Hyperplasia | Parietal-cell Hyperplasia | Rebound Hyperacidity
Trio Medicines Ltd.

Completed

Effects of YF476 and Rabeprazole on Gastric Function

Hypergastrinaemia

United Kingdom
Trio Medicines Ltd.
Biogen

Completed

Avonex®: Safety, Blood Levels and Effects (C-851)

Multiple Sclerosis (MS)

United Kingdom
Columbia University
Trio Medicines Ltd.

Completed

Trial of a Gastrin Receptor Antagonist in Barrett's Esophagus

Barrett's Esophagus

United States, United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
James Black Foundation

Completed

Effect of Repeated Doses of YF476 on Stomach Acidity

Hypergastrinaemia

United Kingdom
Trio Medicines Ltd.
James Black Foundation

Completed

Effect of Single Doses of YF476 on Stomach Acidity

Hypergastrinaemia

United Kingdom
Trio Medicines Ltd.
Royal Liverpool University Hospital

Completed

YF476 and Type I Gastric Carcinoids

Hypergastrinaemia | Chronic Atrophic Gastritis | Type I Gastric Carcinoids

United Kingdom
Trio Medicines Ltd.
Columbia University; University of Cambridge

Completed

YF476 in Barrett's Esophagus

Barrett's Esophagus

United States, United Kingdom
Trio Medicines Ltd.
National Institutes of Health (NIH)

Terminated

YF476 and Type II Gastric Carcinoids

Zollinger-Ellison Syndrome
Trio Medicines Ltd.
Norwegian University of Science and Technology

Terminated

YF476 and Type I Gastric Carcinoids (Norway)

Chronic Atrophic Gastritis | Hypergastrinemia | Type I Gastric Carcinoids

Norway
Tri.O Medical LTD

Recruiting

Proof of Concept Open Label, Clinical Trial to Evaluate the Safety and Efficacy of the "FITT" Device in Diabetic Foot Ulcers Patients (TriO FITT)

Diabetic Foot Ulcer

Israel
Xention Ltd
Ario Pharma Ltd

Completed

A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Xention Ltd
Ario Pharma Ltd

Completed

A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With Chronic Idiopathic Cough

Chronic Idiopathic Cough

United Kingdom, Ireland
LittDD Medicines Ltd

Enrolling by invitation

A Phase I Clinical Trial to Evaluate LIT-00814 Tablets in Patients With Advanced Solid Tumor

Advanced Solid Tumor

China
Sequential Medicine Ltd

Not yet recruiting

SM-1 vs. an Active Comparator in A Model of Transient Insomnia

Transient Insomnia

United States
Sequential Medicine Ltd

Completed

SM-1 vs 2 Comparators and Placebo in Participants With a History of Transient Insomnia.

Transient Insomnia

United States
Sequential Medicine Ltd

Withdrawn

An Investigational Study to Assess Efficacy and Pattern of Use of SM-1 in Subjects With a History of Transient Insomnia

Transient Insomnia
3D Medicines (Sichuan) Co., Ltd.

Recruiting

Phase I Trial of Envafolimab for Healthy Male Subjects

Healthy Male

China
3D Medicines (Sichuan) Co., Ltd.

Recruiting

Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors

Renal Cell Carcinoma | Hepatocellular Carcinoma | Non-small Cell Lung Cancer | Solid Tumors

China
3D Medicines (Sichuan) Co., Ltd.

Recruiting

ENVAFOLIMAB Single-agent Treatment in Patients With Advanced Solid Tumors

Solid Tumor

China
3D Medicines (Sichuan) Co., Ltd.

Recruiting

KN035 for dMMR/MSI-H Advanced Solid Tumors

Solid Tumor

China
3D Medicines (Sichuan) Co., Ltd.

Recruiting

Programmed Death Ligand (PD-L1) Combined With Chemotherapy for Patients With BTC (KN035-BTC)

Biliary Tract Neoplasms

China
3D Medicines (Beijing) Co., Ltd.

Active, not recruiting

A Monotherapy in Subjects With Advanced Solid Tumors

Solid Tumor, Adult

China, United States
3D Medicines (Sichuan) Co., Ltd.

Recruiting

Study of Envafolimab Alone or With Lenvatinib in Patients With Advanced Endometrial Cancer

Advanced Endometrial Cancer

China
3D Medicines (Sichuan) Co., Ltd.

Not yet recruiting

Multicenter Phase 2 Study of Envafolimab in Biliary Tract Cancers

Biliary Tract Neoplasms
3D Medicines (Beijing) Co., Ltd.

Withdrawn

3D011-08 Monotherapy in Subjects With Advanced Solid Tumors

Solid Tumor, Adult

China
3D Medicines (Sichuan) Co., Ltd.

Completed

Phase 1 Study of Anti-PD-L1 Monoclonal Antibody KN035 to Treat Locally Advanced or Metastatic Solid Tumors

Solid Tumors

United States
3D Medicines (Sichuan) Co., Ltd.

Recruiting

Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC

Non-small Cell Lung Cancer

China
3D Medicines (Beijing) Co., Ltd.

Not yet recruiting

Efficacy and Safety of 3D185 Monotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Cholangiocarcinoma

Cholangiocarcinoma,Adult
3D Medicines (Sichuan) Co., Ltd.

Completed

Phase I Study of KN035 in Chinese Subjects With Advanced Solid Tumors

Solid Tumors

China
3D Medicines (Sichuan) Co., Ltd.

Completed

A Study of PD-L1 Antibody KN035 in Japanese Subjects With Locally Advanced or Metastatic Solid Tumors

Advanced or Metastatic Solid Tumors

Japan
Zhejiang Medicine Co., Ltd.

Unknown

Pharmacokinetics Study of Nemonoxacin Malate Capsules in Subjects With Severe Impaired Renal Function

Kidney Dysfunction

China
LaNova Medicines Zhejiang Co., Ltd.

Not yet recruiting

LM-302 for the Treatment of Subjects With Claudin18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma.

Locally Advanced or Metastatic GC and GCJ Adenocarcinoma
LaNova Medicines Zhejiang Co., Ltd.

Active, not recruiting

Study of LM-302 in Patients With Advance Solid Tumors

Advanced Solid Tumor

China
Everest Medicines (Singapore) Pte. Ltd.

Active, not recruiting

Efficacy and Safety in Chinese Patients With Immunoglobulin A Nephropathy (IgAN) Who Have Completed Study Nef-301

Primary Immunoglobulin A Nephropathy (IgAN)

China
LaNova Medicines Zhejiang Co., Ltd.

Recruiting

A LM-302 Combined With Toripalimab Phase II Study

Gastric Cancer | Pancreatic Cancer

China
Stem Cell Medicine Ltd.

Withdrawn

Study to Assess the Safety and Efficacy of an IT Administration of SCM-010 in SPMS

Secondary Progressive Multiple Sclerosis (SPMS)

Israel
Qidong Gaitianli Medicines Co., Ltd

Terminated

Huaier Granule for Prevention of Recurrence and Metastasis of Stage II and III Non-small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

China
Everest Medicines (China) Co.,Ltd.

Recruiting

Evaluate The Efficacy, Safety, Pharmacokinetics And Pharmacodynamics Of EVER001

Primary Membranous Nephropathy

China
Everest Medicines (Singapore) Pte. Ltd.

Not yet recruiting

Booster Study of PTX-COVID19-B in Adults Aged 18 Years and Older

SARS-CoV-2 Infection
Everest Medicines (Singapore) Pte. Ltd.

Not yet recruiting

Booster Superiority Study of PTX-COVID19-B Compared to Vaxzevria® in Adults Aged 18 Years and Older

SARS-CoV-2 Infection
Praxis Precision Medicines
Praxis Precision Medicines Australia Pty Ltd

Completed

A Clinical Trial of PRAX-944 in Participants With Essential Tremor

Essential Tremor

United States, Australia, New Zealand
Medikine, Inc.
Medikine Australia Pty Ltd.

Completed

A Single Ascending Dose Study to Evaluate MDK-703 in Healthy Adult Volunteers

Healthy Volunteers

Australia
Jiangsu HengRui Medicine Co., Ltd.
Atridia Pty Ltd.

Recruiting

A Study of SHR-A1811 in Subjects With Advanced Malignant Solid Tumors

Advanced Solid Tumors

China, Korea, Republic of, Taiwan, United States, Australia
Medicines Evaluation Unit Ltd
Chiesi UK

Completed

A Study Comparing the Effects of Trimbow to Fostair in COPD (TRIFLOW)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Bioavailability and Food Effects of HRS-7535 Tablets With Different Formulating Processes in Healthy Subjects

Type 2 Diabetes Mellitus

China

Clinical Trials Sponsored by Trio Medicines Ltd.

Sponsors and Collaborators

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