Clinical Trials Sponsored by Tyme, Inc

Total 35664 results

Newcastle University
Northumberland, Tyne and Wear NHS Foundation Trust

Completed

Cognitive Therapy for Distressing Visual Hallucinations: A Pilot Study

Psychotic Disorders | Visual Hallucinations

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
University of Newcastle Upon-Tyne; North Tyneside Primary Care Trust; Northumberland...

Completed

Pilot: Group Therapy for Children Who Stammer

Stammering

United Kingdom
University Hospital, Montpellier
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Clinical Validation of a Mobility Monitor to Measure and Predict Health Outcomes (MOBILISE-D)

Hip Fractures

France
Newcastle-upon-Tyne Hospitals NHS Trust
AstraZeneca; Newcastle University

Completed

Anti-platelet Therapy in the Prevention of Cardiovascular Disease in Patients With COPD (APPLE-COPD: ICON 2)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Cancer Research UK

Completed

A Feasibility Study for a Multicentre Randomised Controlled Trial to Compare Surgery With Needle Ablation Techniques in People With Small Renal Masses (4cm) (CONSERVE)

Renal Cancer

United Kingdom
TME Pharma AG
Merck Sharp & Dohme LLC

Not yet recruiting

Olaptesed With Pembrolizumab and Nanoliposomal Irinotecan or Gemcitabine/Nab-Paclitaxel in MSS Pancreatic Cancer (OPTIMUS)

Metastatic Pancreatic Cancer
TME Pharma AG
Merck Sharp & Dohme LLC

Completed

Olaptesed (NOX-A12) Alone and in Combination With Pembrolizumab in Colorectal and Pancreatic Cancer (Keynote-559)

Metastatic Colorectal Cancer | Metastatic Pancreatic Cancer

Germany
TME Pharma AG
Profil Institut für Stoffwechselforschung GmbH

Completed

NOX-E36 Multiple Ascending Dose Study in Healthy Volunteers and Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Germany
Shandong New Time Pharmaceutical Co., LTD
Sun Yat-sen University

Not yet recruiting

Phase I Study of LNF1901 in Advanced Malignant Tumors

Advanced Malignant Tumors
Newcastle University
Newcastle-upon-Tyne Hospitals NHS Trust; Unilever SEAC

Completed

Metagenome Resilience in Experimental Gingivitis

Gingivitis | Oral Disease

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
The Urology Foundation, UK

Unknown

Hyaluronate for the Treatment and Prevention of Recurrent Urinary Tract Infection in Women Suffering Atrophic Vaginitis (HATPIN)

Urinary Tract Infections | Atrophic Vaginitis

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Wellcome Trust; Newcastle University

Completed

Pilot Study of Ultrasound in Rheumatoid Arthritis

Rheumatoid Arthritis

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Wellcome Trust; Newcastle University

Completed

Biomarkers of Remission in Rheumatoid Arthritis (BioRRA) (BioRRA)

Rheumatoid Arthritis

United Kingdom
Northumbria Healthcare NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Influence of Reliance on Historical Blood Eosinophil Counts on ICS Prescribing by GOLD 2019 Thresholds in COPD (BECCOPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Jagiellonian University
Piotr Chlosta, Full-time Professor, University Hospital, Cracow, Poland

Completed

Polish Translation and Validation of NBSS, Qualiveen and SF-Qualiveen

Multiple Sclerosis | Spinal Cord Injuries

Poland
Resolve Therapeutics
Newcastle-upon-Tyne Hospitals NHS Trust; University Hospital Birmingham

Completed

A Study of RSLV-132 in Subjects With Primary Sjogren's Syndrome (RSLV-132)

Sjogren's Syndrome

United Kingdom
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.; Oncoceutics, Inc.

Recruiting

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

Metastasis | Endometrial Cancer

United States
NC Medial Research Inc

Recruiting

A Study of NCS-01 in Patients With Acute Ischemic Stroke

Ischemic Stroke

United States
IC-IT Sciences Inc.

Unknown

Comparison of the Natural Frequencies Technology Sleep Patches to Sham Patches During Sleep in the Home Environment

Sleep Disturbance

United States
Cardiff University
University of Birmingham; Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Primary Care Management of Lower Urinary Tract Symptoms in Men (PriMUS)

Lower Urinary Tract Symptoms

United Kingdom
Newcastle University
Newcastle-upon-Tyne Hospitals NHS Trust; Arthritis Research UK

Completed

Autologous Tolerogenic Dendritic Cells for Rheumatoid Arthritis (AutoDECRA) (AutoDECRA)

Rheumatoid Arthritis

United Kingdom
Balt USA
AXIOM Real Time Metrics; Embo-Flüssigkeiten A.G.; Balt Extrusion

Active, not recruiting

The SQUID Trial for the Embolization of the Middle Meningeal Artery for Treatment of Chronic Subdural Hematoma (STEM) (STEM)

Subdural Hematoma, Chronic

United States, France, Germany, Spain
Newcastle-upon-Tyne Hospitals NHS Trust
Medical Research Council; Newcastle University

Completed

Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? (GMCSF)

Sepsis | Critical Illness | Immuno-suppression

United Kingdom
South Tees Hospitals NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust

Not yet recruiting

Thrombogenicity of Lipoprotein A: Laboratory Study Defining the Prothrombotic Effects of Lipoprotein A

Cardiac Disease | Cardiovascular Disease and Lipid Disorders

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; British Heart Foundation

Active, not recruiting

The British Heart Foundation SENIOR-RITA Trial (SENIOR-RITA)

NSTEMI - Non-ST Segment Elevation MI

United Kingdom
Zhengzhou Gensciences Inc
Haimen Gensciences lnc

Completed

An Open Label Study to Determine the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A.

Hemophilia A

China
Zhengzhou Gensciences Inc
Jiangsu Gensciences lnc.

Completed

Phase III Expansion Trial for Determining the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A (RH-107-III02)

Hemophilia A

China
The Danish Center for Strategic Research on Type...
Odense University Hospital

Completed

Interval Walking Intervention for Pregnant Women Diagnosed With Gestational Diabetes Mellitus

Gestational Diabetes Mellitus in Pregnancy

Denmark
Milton S. Hershey Medical Center
AXIOM Real Time Metrics; Analytica Ventures LLC

Recruiting

SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial (SNOW)

Covid19 | SARS-CoV Infection

United States
Newcastle-upon-Tyne Hospitals NHS Trust
Biotechnology and Biological Sciences Research Council

Completed

Bioactive Dietary Fibres and Obesity (FIBREFOODS)

Obesity
Newcastle-upon-Tyne Hospitals NHS Trust
University of Nottingham; Quadram Institute Bioscience

Completed

Where is the Initial Site of Biotransformation of Folates in Humans? (FOLTIPS)

Healthy

United Kingdom
UNC Lineberger Comprehensive Cancer Center
Seagen Inc.

Completed

Induction Chemo w/ABVD Followed by Brentuximab Vedotin Consolidation in Newly Diagnosed, Non-Bulky Stage I/II Hodgkin Lymphoma

Hodgkin Lymphoma, Adult

United States
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.

Terminated

Efalizumab in Treating Patients With Graft-Versus-Host Disease of the Skin That Did Not Respond to Previous Steroids (NRR)

Graft Versus Host Disease

United States
TME Pharma AG
German Federal Ministry of Education and Research

Completed

NOX-A12 First-in-human (FIH) Study

Autologous Stem Cell Transplantation

Germany
UNC Lineberger Comprehensive Cancer Center
Veracyte, Inc.

Recruiting

Harnessing Analysis RNA Expression and Molecular Subtype to Optimize Novel TherapY MBCA (HARMONY)

Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Seagen Inc.

Active, not recruiting

BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma

Lymphoma | Lymphatic Diseases | Adult T-Cell Leukemia/Lymphoma

United States
IGC Pharma LLC

Completed

Study of IGC-AD1 in Subjects With Dementia Due to Alzheimer's Disease

Dementia of Alzheimer Type

Puerto Rico
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.

Completed

Cancer Patients' Performance Status Assessed Using Cardiopulmonary Exercise Testing and Wearable Data Generation

Hematologic Malignancies | Malignant Solid Tumor

United States
IGC Pharma LLC

Recruiting

IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's (IGC-AD1-P2)

Aggression | Depression | Anxiety | Alzheimer Disease | Memory Impairment | Agitated; State, Acute Reaction to Stress | Agitation,Psychomotor | Care Giving Burden | NPS | Aggressive Outburst

United States, Canada, Puerto Rico
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.

Recruiting

Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-cell Lymphoma

United States
Johns Hopkins Bloomberg School of Public Health
Time-sharing Experiments for the Social Sciences

Completed

Do Sustainability Labels Lead to More Sustainable and Healthier Food Choices? (Climate Labels)

Food Selection | Attitude

United States
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom

Completed

A Novel Home-based Physical Activity Intervention for Stable Chronic Heart Failure Patients (PAHF)

Heart Failure, Systolic
Novan, Inc.
Synteract, Inc.; Therapeutics, Inc.

Completed

A Phase 3 Molluscum Contagiosum Efficacy and Safety Study (B-SIMPLE4)

Molluscum Contagiosum

United States
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom

Completed

Study of Optimal Replacement of Thyroxine in the Elderly (SORTED)

Hypothyroidism

United Kingdom
OBELAB, Inc.
Helptrial Inc.

Not yet recruiting

Evaluation of rSO2 Between Frontal Lesion Area and Normal Area of Brain by NIRSITX Using NIRS in Acute Ischemic Stroke Patients.

Acute Ischemic Stroke Patients

Korea, Republic of
Athersys, Inc
Medpace, Inc.

Recruiting

MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study (MASTERS-2)

Ischemic Stroke

United States, Taiwan
89bio, Inc.
ProSciento, Inc.

Completed

A Multiple Ascending Dose Study of Pegozafermin in Participants With Biopsy Confirmed Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) and at High Risk of NASH

NASH

United States, Puerto Rico
ModernaTX, Inc.
Aetion, Inc.

Active, not recruiting

Post-marketing Safety of Elasomeran/Davesomeran and Andusomeran

SARS-CoV-2

United States
Eisai Inc.
Quintiles, Inc.

Terminated

FOLFIRI Alone Versus FOLFIRI Plus Bevacizumab Versus FOLFIRI Plus E7820 as Second-Line Therapy in Patients With Locally Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

United States, Australia, Russian Federation, India, Ukraine
AxeroVision, Inc.
ORA, Inc.

Completed

A Study to Evaluate AXR-159 Ophthalmic Solution in Patients With Dry Eye Disease

Dry Eye

United States

Clinical Trials Sponsored by Tyme, Inc

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