Clinical Trials Sponsored by Wave Neuroscience

Total 1834 results

Spaulding Rehabilitation Hospital
Rio Grande Neurosciences

Withdrawn

Pulsed Electromagnetic Field (PEMF) Therapy for Post-Concussive Syndrome (PEMF)

Concussion | Post Concussive Syndrome
Center for Neurosciences, Tucson
Genentech, Inc.

Completed

Bi-weekly Temozolomide Plus Bevacizumab for Adult Patients With Recurrent Glioblastoma Multiforme

Recurrent Glioblastoma Multiforme | Recurrent Gliosarcoma

United States
Third Wave Therapeutics

Recruiting

Sonu Real-World Use Clinical Study to Treat Moderate to Severe Nasal Congestion

Nasal Congestion

United States
V-Wave Ltd

Withdrawn

Heart Failure (HF) Interatrial Shunt Study 1

Chronic Heart Failure

Israel
The Board of Medicine
Apollo Neuroscience, Inc.

Recruiting

Effect of Apollo Wearable on Long COVID-19 Symptoms.

Post-acute Sequelae of SARS-COV-2 Infection

United States
National Neuroscience Institute
HiCura Medical Pte Ltd

Recruiting

uSINE-PAMS Artificial Intelligence Driven, Ultrasound-Guided Lumbar Puncture to Improve Procedural Accuracy

Ultrasound Therapy | Lumbar Puncture

Singapore
Neuroscience Trials Australia
China Medical University Hospital

Completed

EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) (EXTEND)

Stroke

Taiwan
Charlottesville Neuroscience
Takeda Pharmaceuticals North America, Inc.

Terminated

A Double-Blind Placebo-Controlled Trial of Rozerem in Migraine Headaches

Migraine Headache

United States
New York Neurosurgery & Neuroscience Associates...
MedtronicNeuro

Unknown

Spinal Cord Stimulation Efficacy Measures

Chronic Pain in the Trunk and Limbs

United States
The Hong Kong Polytechnic University
Neuroscience Research Australia

Unknown

Community-based Rehabilitation and Fall Prevention Program After Total Knee Arthroplasty

Knee Osteoarthritis | Fall

Hong Kong
Tel-Aviv Sourasky Medical Center
NIBS NeuroScience Technologies

Unknown

A Novel Non Invasive Brain Stimulation Based Treatment for Chronic Low Back Pain (CLBP)

Chronic Low Back Pain
Brown, Theodore R., M.D., MPH
Teva Neuroscience, Inc.

Completed

Diclofenac Sodium Topical Gel to Reduce Injection Site Discomfort in Patients Taking Glatiramer Acetate

Multiple Sclerosis

United States
Singhealth Foundation
Changi General Hospital; National Neuroscience Institute

Terminated

Neuroprotection With Minocycline Therapy for Acute Stroke Recovery Trial (NeuMAST)

Acute Stroke

Singapore
University Hospital, Montpellier
Institute for Neuroscience Montpellier

Not yet recruiting

Implementation of a Protocol for the Transdifferentiation of Buccal Mucosal Epithelium Into Corneal Epithelium (TransBuCor)

Limbal Stem Cell Deficiency

France
Apollo Neuroscience, Inc.
The Board of Medicine

Recruiting

Sustaining Remission From PTSD Using Tuned Vibroacoustic Stimulation (TVS) Following MDMA-Assisted Psychotherapy

Stress Disorders, Post-Traumatic

United States
University of Maryland, Baltimore
Neuroscience Research Australia

Completed

Validation of a Novel Cortical Biomarker Signature for Pain (PREDICT)

TMD

United States, Australia
University of California, San Francisco
Halo Neuroscience

Withdrawn

tDCS and Speech Therapy for Motor Speech Disorders Caused by FTLD Syndromes: a Feasibility Study

Corticobasal Degeneration | Progressive Supranuclear Palsy | Behavioral Variant of Frontotemporal Dementia | Primary Progressive Nonfluent Aphasia | Nonfluent Aphasia, Progressive | Primary Progressive Non Fluent Aphasia
Dent Neuroscience Research Center
University at Buffalo

Completed

Study of Lamotrigine to Treat Ménière's Disease

Meniere's Disease | Ménière's Vertigo | Vertigo, Intermittent | Vertigo, Aural

United States
Singapore General Hospital
Novartis; National Neuroscience Institute

Completed

RIVastigmine In Vascular cognitivE Impairment (RIVIVE)

Cognitive Impairment

Singapore
Advanced Neurosciences Institute
Novel Pharmaceutics Institute

Unknown

Immunodeficiency in MS

Multiple Sclerosis | Infection, Bacterial | Immunodeficiency | Hypogammaglobulinemia

United States
Evotec Neurosciences GmbH

Completed

Efficacy Study of EVT 201 to Treat Insomnia

Sleep Initiation and Maintenance Disorders

United States
Evotec Neurosciences GmbH

Completed

Efficacy Study of EVT 201 in the Treatment of Elderly Patients With Daytime Sleepiness

Sleep Initiation and Maintenance Disorders

United States
University Hospital, Grenoble
Grenoble Institut des Neurosciences

Recruiting

Towards the Validation of a New Blood Biomarker for the Early Diagnosis of Parkinson's Disease (BIOPARK)

Parkinson Disease

France
National Institute of Neurosciences and Hospital...

Completed

Insulin for Hyperglycemia in Stroke Trial

Hyperglycemia | Stroke, Acute

Bangladesh
Neurotrope Bioscience, Inc.
Blanchette Rockefeller Neurosciences Insitute

Terminated

Study to Evaluate the Preliminary Safety, Efficacy, PK and PD of Bryostatin 1 in Patients With Alzheimer's Disease

Alzheimer's Disease

United States
Evotec Neurosciences GmbH

Completed

Effects of EVT 302 With or Without NRT on Craving and Withdrawal in Healthy Male Smokers Deprived of Cigarettes

Smoking Cessation

Germany
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
First Wave BioPharma, Inc.

Completed

Study to Assess an Enteric Microgranule Formulation of Adrulipase in Patients With Cystic Fibrosis (SPAN)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Wave Life Sciences Ltd.

Terminated

Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD)

ALS | FTD

Netherlands, United Kingdom
First Wave Bio, Inc.

Withdrawn

Niclosamide In Moderate COVID-19

COVID
First Wave Bio, Inc.

Withdrawn

Niclosamide in COVID-19

Covid19
Wave Life Sciences Ltd.

Terminated

Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease (PRECISION-HD1)

Huntington's Disease

Denmark, Canada, Australia, United Kingdom, France, Germany, Poland
Wave Life Sciences Ltd.

Terminated

Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease

Huntington Disease

Denmark, Australia, Canada, France, United Kingdom, Germany, Poland
Wave Life Sciences Ltd.

Completed

Safety and Tolerability of WVE-210201 in Patients With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Belgium, United Kingdom, France, United States, Italy, Canada, Netherlands
Wave Life Sciences Ltd.

Recruiting

Study of WVE-003 in Patients With Huntington's Disease

Huntington Disease

Canada, Spain, Australia, Denmark, Netherlands, Poland, United Kingdom, France, Germany, Italy
First Wave BioPharma, Inc.

Active, not recruiting

Safety and Efficacy of Niclosamide in Patients With COVID-19 With Gastrointestinal Infection (RESERVOIR)

Covid19

United States, Ukraine, India
First Wave Bio, Inc.

Completed

OPTION 2: A Trial to Assess the Safety and Efficacy of MS1819 in Enteric Capsules in Patients With Cystic Fibrosis

Cystic Fibrosis (CF) | Exocrine Pancreatic Insufficiency (EPI)

United States, Poland
First Wave Bio, Inc.

Completed

OPTION: A Trial to Assess the Safety & Efficacy of MS1819 in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis (OPTION)

Cystic Fibrosis (CF) | Exocrine Pancreatic Insufficiency (EPI)

United States, Poland
Wave Life Sciences Ltd.

Terminated

Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease (PRECISION-HD2)

Huntington's Disease

United States, Denmark, Canada, Australia, United Kingdom, France, Germany, Poland
Wave Life Sciences Ltd.

Terminated

Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease

Huntington Disease

Denmark, Australia, Canada, France, United Kingdom, Germany, Poland
Wave Life Sciences Ltd.

Terminated

Efficacy and Safety Study of WVE-210201 (Suvodirsen) With Open-label Extension in Ambulatory Patients With Duchenne Muscular Dystrophy (DYSTANCE 51)

Duchenne Muscular Dystrophy

United States, Belgium, United Kingdom, Czechia, Canada, France, Italy, Sweden
University of Rochester
Schmitt Program on Integrative Neuroscience

Recruiting

A Study of Cognitive Changes in Patients Receiving Brain Radiation

Brain Tumor Adult

United States
Aspen Neuroscience
California Institute for Regenerative Medicine (CIRM)

Enrolling by invitation

Phase 1/2a Study of ANPD001 in Parkinson Disease (ASPIRO)

Parkinson Disease

United States
Asceneuron Pty Ltd.
Neuroscience Trials Australia; Asceneuron S.A.

Terminated

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of Oral ASN51 in Healthy Subjects and Subjects With Alzheimer's Disease

Alzheimer Disease

Australia
Alto Neuroscience
National Institute of Mental Health (NIMH)

Withdrawn

Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram (LEAP-SE)

Major Depressive Disorder
Wave Life Sciences Ltd.

Active, not recruiting

Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)

Duchenne Muscular Dystrophy

Jordan, United Kingdom
Wave Life Sciences Ltd.

Terminated

Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD) (FOCUS-C9)

ALS | FTD

Canada, Belgium, New Zealand, Netherlands, Australia, Sweden, United Kingdom, Ireland
First Wave Bio, Inc.

Terminated

A Study of Niclosamide Enemas in Subjects With Active Ulcerative Proctitis or Ulcerative Proctosigmoiditis

Ulcerative Colitis | Ulcerative Proctitis | Ulcerative Proctosigmoiditis

Italy
National Neuroscience Institute
Dr. Willmar Schwabe GmbH & Co. KG

Recruiting

EGb 761 in the Syndrome of MCI With Concomitant CVD

Mild Cognitive Impairment | Cerebrovascular Disease

Singapore
Neuroscience Research Australia
The University of New South Wales

Completed

The SafeTrip Study - Step Training to Reduce Falls in Older Adults

Fall | Fall Injury

Australia

Clinical Trials Sponsored by Wave Neuroscience

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