Clinical Trials Sponsored by medac GmbH

Total 3345 results

medac GmbH

Recruiting

Treatment Of Steroid-Refractory Acute Graft-versus-host Disease With Mesenchymal Stromal Cells Versus Best Available Therapy (IDUNN)

Steroid-refractory Acute Graft-versus-host Disease

Spain, Germany, France, Poland, Sweden
medac GmbH

Completed

Preference Methotrexate (MTX) Pre-filled Syringe Versus Pre-filled Pen in Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Germany
medac GmbH

Completed

Comparative Efficacy and Safety of Two Asparaginase Preparations in Children With Previously Untreated Acute Lymphoblastic Leukaemia

Acute Lymphoblastic Leukemia

Netherlands
medac GmbH

Completed

Efficacy and Safety of Recombinant Asparaginase in Infants With Previously Untreated Acute Lymphoid Leukemia (ALL)

Acute Lymphoid Leukemia

Germany, Netherlands
medac GmbH

Completed

Treosulfan Based Conditioning Acute Myeloid Leukaemia (AML)

Acute Myeloid Leukaemia

Germany
medac GmbH

Not yet recruiting

Efficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis.

Moderate to Severe Atopic Dermatitis
medac GmbH

Completed

Dose-range Finding Treosulfan-based Conditioning

Hematological Malignancies

Germany, Finland, Poland, Sweden
medac GmbH

Completed

Clinical Phase III Trial Treosulfan-based Conditioning Versus Reduced-intensity Conditioning (RIC)

Acute Myeloid Leukemia | Myelodysplastic Syndrome

Germany, Italy, Poland, France, Finland, Hungary
medac GmbH

Terminated

Urokinase Therapy in Patients With Diabetic Foot Syndrome

Ischemia | Diabetic Foot | Arterial Occlusive Disease

Germany
medac GmbH

Completed

Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid

Brain Cancer | Brain Tumors | Brain Tumor, Primary | Primary Brain Tumors | Cancer of Brain
medac GmbH

Completed

Urokinase Therapy in Diabetic Foot Syndrome

Ischemia | Diabetic Foot | Arterial Occlusive Disease

Germany
medac GmbH

Recruiting

Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease (BALDER)

Steroid-refractory Acute Graft-versus-host Disease

Germany, Spain, France, Poland
medac GmbH

Terminated

Trial of Oncaspar® and Three Doses of Pegylated Recombinant Asparaginase in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukaemia

Acute Lymphoblastic Leukaemia

Germany
medac GmbH

Completed

Treosulfan Based Conditioning Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome

Finland
medac GmbH
IKP

Completed

Clinical Study on 5-aminolevulinic Acid Hydrochloride (5-ALA) for Fluorescence-guided Resection of Malignant Gliomas

Brain Neoplasm
medac GmbH
PPD

Completed

Human Factors Study of Methotrexate Prefilled Pen (50 mg/mL) in Patients With Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

United States
medac GmbH
PPD

Completed

Bioavailability in Patient With Psoriasis: Metoject Prefilled Pen

Psoriasis

United States
medac GmbH
PPD

Completed

Evaluation of Patient Performance Using the Metoject Device for Subcutaneous Injection in Rheumatoid Arthritis (RA)Patient

Rheumatoid Arthritis (RA)

United States
medac GmbH
Synteract, Inc.

Recruiting

Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics

Myelodysplastic Syndrome (MDS) | Acute Myeloid Leukaemia (AML) | Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

United States
medac GmbH
Syneos Health

Recruiting

PK, PD, Safety and Immunogenicity of Spectrila in Adults With Acute B-cell Lymphoblastic Leukaemia

Acute B-Cell Lymphoblastic Leukaemia

Brazil
medac GmbH
Syneos Health; Celerion

Completed

Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies

Myelodysplastic Syndromes (MDS) | Acute Lymphoblastic Leukaemias (ALL) | Acute Myeloid Leukaemias (AML) | Juvenile Myelomonocytic Leukaemias (JMML)

Germany, United Kingdom, Italy, Austria, Czechia, Poland
Fred Hutchinson Cancer Center
medac GmbH

Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Acute Myeloid Leukemia | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Mantle Cell Lymphoma | Lymphoplasmacytic Lymphoma | Anaplastic Large Cell Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Prolymphocytic Leukemia | Refractory... and other conditions

United States
CONKO-Studiengruppe
Sanofi; Amgen; medac GmbH

Approved for marketing

A Phase III Second Line Trial in Advanced Pancreatic Cancer CONKO 003

Pancreatic Cancer
Westfälische Wilhelms-Universität Münster
photonamic GmbH & Co. KG; medac GmbH

Recruiting

Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Supratentorial Brain Tumors

Brain Tumor, Pediatric

Germany, Netherlands
Wuerzburg University Hospital
Celgene Corporation; Amgen; ClinAssess GmbH; medac GmbH

Completed

Lenalidomide-Adriamycin-Dexamethasone (RAD) Induction Followed by Stem Cell Transplant in Newly Diagnosed Multiple Myeloma

Multiple Myeloma

Germany
Flinders University
medac GmbH; University of South Australia

Recruiting

Methotrexate, Blood Pressure and Arterial Function in Rheumatoid Arthritis

Rheumatoid Arthritis | Endothelial Dysfunction | Cardiovascular Risk Factor | Stiffness, Aortic

Australia
medac GmbH
Syneos Health; Celerion; Venn Life Sciences

Completed

Treosulfan-based Versus Busulfan-based Conditioning in Paediatric Patients With Non-malignant Diseases

Bone Marrow Failure Syndromes | Inborn Errors of Metabolism | Primary Immunodeficiencies | Haemoglobinopathies

Poland, Czechia, Germany, Italy
CONKO-Studiengruppe
Eli Lilly and Company; medac GmbH

Completed

Chemotherapeutic Trial With Gemcitabine, Cisplatin, 5-FU and Folinic Acid in Esophageal Cancer (CONKO-101)

Esophageal Cancer

Germany
MEDA Pharma GmbH & Co. KG
ClinResearch, GmbH; Prolytic GmbH

Completed

Single Dose Pharmacokinetics of Intranasal Azelastine Delivered by a Fixed Combination With Fluticasone in Comparison to Azelastine Nasal Sprays

Allergic Rhinitis

Germany
University Hospital Muenster
Deutsche Krebshilfe e.V., Bonn (Germany); photonamic GmbH & Co. KG; medac GmbH; LifePhotonic GmbH

Recruiting

Stereotactical Photodynamic Therapy With 5-aminolevulinic Acid (Gliolan®) in Recurrent Glioblastoma (NOA11)

Glioblastoma Multiforme, Adult

Germany
MEDA Pharma GmbH & Co. KG
ClinResearch, GmbH; Prolytic GmbH; pharm-analyt GmbH

Completed

Single Dose Pharmacokinetics of Intranasal Fluticasone Delivered by a Fixed Combination With Azelastine (MP29 02) in Comparison to Two Different Fluticasone Nasal Sprays

Allergic Rhinitis

Germany
MEDA Pharma GmbH & Co. KG
Sanofi; ClinResearch, GmbH

Completed

To Assess the Protective Effect of the Fixed Drug Combination of Disodium Cromoglycate Plus Reproterol (AERIA)

Asthma, Exercise-Induced

Germany
AGO Study Group
Philipps University Marburg Medical Center; medac GmbH

Completed

Chemo- and Radiotherapy in Epithelial Vulvar Cancer (CARE)

Radio/Chemotherapy in Node Positive Advanced Vulvar Cancer

Germany
OHSU Knight Cancer Institute
National Cancer Institute (NCI); medac GmbH

Completed

Treosulfan and Fludarabine in Treating Younger Patients Who Are Undergoing a Donor Stem Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia

United States
MEDA Pharma GmbH & Co. KG

Completed

Dymista Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
MEDA Pharma GmbH & Co. KG

Completed

Aldara for the Treatment of Large and/or Multiple sBCC

Carcinoma, Basal Cell

France
MEDA Pharma GmbH & Co. KG

Completed

5-Year Safety Study of Pimecrolimus Cream 1% in Infants 3 - 12 Months of Age With Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

United States, Germany
MEDA Pharma GmbH & Co. KG

Completed

Study of Imiquimod Cream Prior to Ablative Therapy in External Ano-Genital Warts

Genital Warts

Italy
MEDA Pharma GmbH & Co. KG

Completed

Evaluation of Two Different Non-invasive Techniques to Monitor the Clearance of Actinic Keratosis Lesions

Actinic Keratosis

France
MEDA Pharma GmbH & Co. KG

Recruiting

Real-world Evidence Study on Cystistat (IC/BPS)

Interstitial Cystitis and Bladder Pain Syndrome

Austria
MEDA Pharma GmbH & Co. KG

Completed

Azelastine Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
MEDA Pharma GmbH & Co. KG

Completed

A Study to Evaluate Effectiveness of Imiquimod 5% Cream in Superficial Basal Cell Carcinoma

Basal Cell Carcinoma

Germany
MEDA Pharma GmbH & Co. KG

Completed

A Study to Follow up Recurrence Rates of Actinic Keratoses One Year After Completion of Study 1487-IMIQ

Actinic Keratoses
MEDA Pharma GmbH & Co. KG

Completed

A Study to Evaluate the Effectiveness and Safety of Multiple Applications of Imiquimod 5% Cream for the Treatment of Actinic Keratoses in Organ Transplant Recipients

Actinic Keratosis
MEDA Pharma GmbH & Co. KG

Completed

Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Symptomatic Diabetic Neuropathy (SYDNEY 2)

Diabetic Polyneuropathy

Israel, Russian Federation
Prof. Dr. med. Dirk Schadendorf
Boehringer Ingelheim; medac GmbH; Alcedis GmbH

Completed

Efficacy and Safety of Nintedanib Combined With Paclitaxel Chemotherapy for Patients With BRAF wt Metastatic Melanoma (NIPAWILMA)

Cutaneous Malignant Melanoma

Germany
MEDA Pharma GmbH & Co. KG

Completed

MP-AzeFlu Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
MEDA Pharma GmbH & Co. KG

Completed

DYmista NAsal Spray in CHInese Patients (DYNAS-CHI)

Allergic Rhinitis

China
MEDA Pharma GmbH & Co. KG

Completed

Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses (LEIDA)

Actinic Keratosis

Austria, Germany, France
MEDA Pharma GmbH & Co. KG

Completed

To Evaluate the Impact of Oral Flecainide on Quality of Life in Patients With Paroxysmal Atrial Fibrillation

Atrial Fibrillation

France

Clinical Trials Sponsored by medac GmbH

Sponsors and Collaborators

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