Search clinical trials for: 1b

Total 791 results

Yi Han
Qianfoshan Hospital

Recruiting

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

Renal Insufficiency | Gene Polymorphism | Edoxaban

China
University of Colorado, Denver
Usona Institute

Not yet recruiting

A Phase 1b Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence

Breast Cancer | Ovarian Cancer

United States
Xeno Biosciences

Not yet recruiting

A Phase 1b Study to Evaluate the Safety of XEN-101

Obesity
M.D. Anderson Cancer Center

Not yet recruiting

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

Metastatic Colorectal Cancer | KRAS G12C Mutations

United States
Wave Life Sciences Ltd.

Not yet recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency
Chugai Pharmaceutical

Not yet recruiting

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Antiphospholipid Syndrome (APS) | Immune Thrombocytopenia (ITP) | Dermatomyositis (DM) | Bullous Pemphigoid (BP) | Behçet's Syndrome (BS) | Immune-mediated Necrotizing Myopathy (IMNM)

United States, Japan
7 Hills Pharma, LLC

Not yet recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Melanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditions

United States
Sichuan University
Chengdu Brilliant Pharmaceutical Co., Ltd.

Not yet recruiting

Phase I Clinical Study of α-PD-L1/DLL3 CAR-T in Patients With R/R SCLC

Small Cell Lung Cancer Extensive Stage
University of Southern California
National Cancer Institute (NCI)

Not yet recruiting

A Validation Study to Determine Concordance of Liquid Biopsy and Breast Cancer Diagnosis

Breast Carcinoma

United States
Actym Therapeutics, Inc.

Not yet recruiting

A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors

Solid Tumor

Australia
Pharma Nueva

Not yet recruiting

Bioequivalence Study of Generic Racecadotril 100 mg Capsules Under Fasting Conditions

Healthy Vollunteer
University of Southern California
National Cancer Institute (NCI)

Not yet recruiting

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery

Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage 0 Breast Cancer AJCC v8 | Localized Breast Carcinoma

United States
Ferring Pharmaceuticals

Recruiting

A Phase 1b Proof-of-concept Trial Exploring the Effects of FE 999322 and FE 999324 in Adults With Mild to Moderate Ulcerative Colitis

Ulcerative Colitis

United States
Henan Cancer Hospital

Recruiting

The Maintenance Treatment of "ITIVA" in AML Patients

Acute Myeloid Leukemia | Thalidomide | Maintenance Treatment | Minor Residue Disease | Interferon-α-1b | Interleukin-2 | Venentoclax | Azacitidine

China
Iambic Therapeutics, Inc

Recruiting

A Phase 1/1b Study of IAM1363 in HER2 Cancers

HER2 Mutation-Related Tumors

United States
Neuracle Science Co., LTD.
Samsung Medical Center; Korea University Anam Hospital; Severance Hospital

Recruiting

A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL Patients

Sudden Sensorineural Hearing Loss | Seneorineural Deafness

Korea, Republic of
Zdeněk Šumník

Recruiting

Managing of Missed Meal Bolus by HCL Systems (NOELLE)

Diabetes Mellitus, Type 1

Czechia
Benitec Biopharma, Inc.

Recruiting

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Oculopharyngeal Muscular Dystrophy

United States
Sinovac Research and Development Co., Ltd.

Recruiting

A Phase 1b Clinical Trial of 13-valent Pneumococcal Polysaccharide Conjugate Vaccine

Pneumococcal Infectious Disease

China
Prokarium Ltd

Recruiting

A Phase 1/1b Study of ZH9 Treatment in Patients With Non-Muscle Invasive Bladder Cancer (PARADIGM-1)

NMIBC | Non Muscle Invasive Bladder Cancer | High Risk NMIBC

United States
University of Southern California
National Cancer Institute (NCI)

Recruiting

Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses

Breast Carcinoma

United States
Servier Bio-Innovation LLC
Regeneron Pharmaceuticals; Institut de Recherches Internationales Servier

Not yet recruiting

Phase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer (NSCLC)

Hong Kong, United States, Australia
Mridula George, MD

Recruiting

RADIANT: Pre-op Radiation With Abemaciclib and Letrozole

Breast Cancer

United States
Lantern Pharma Inc.

Recruiting

A Study of LP-284 in Relapsed or Refractory Lymphomas and Solid Tumors

Advanced Solid Tumor | Relapsed or Refractory Lymphomas

United States
IGM Biosciences, Inc.

Recruiting

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

Arthritis | Arthritis, Rheumatoid | Rheumatoid Arthritis

United States, Poland
Assiut University

Recruiting

Potential Role of Inflammasome NLRP3 And IL-1B Gene Expression in COVID-19 Patients: Impact of Ferretin and D -Dimer.

Inflammasome NLRP3 And IL-1B Gene Expression in COVID-19 Patients

Egypt
Genmab
BioNTech SE

Recruiting

A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors

Malignant Solid Tumor

Japan
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)

Head and Neck Cancer

Taiwan, United States, Korea, Republic of, Spain, Belgium, Israel
Bayer
Biogen Netherlands B.V; Novartis Europharm Limited; Merck Europe B.V.

Not yet recruiting

An Observational Study to Learn About the Interferon-beta Exposure of Pregnant Women During the Second and Third Trimester in Finland and Sweden (INFORM)

Multiple Sclerosis (MS)

Sweden, Finland
Escient Pharmaceuticals, Inc

Recruiting

Phase 1b, Open-Label Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of EP262 in Subjects With Chronic Inducible Urticaria (CALM-CIndU)

Chronic Inducible Urticaria

Spain, United States, Germany, Canada, Netherlands
Jacinto Convit World Organization Inc.
Instituto Oncologico Luis Razetti; Fundación Jacinto Convit

Not yet recruiting

A Phase 1b/2 Clinical Trial to Evaluate the Safety and Efficacy of ConvitVax in Metastatic Breast Cancer

Metastatic Breast Cancer

United States, Venezuela
M.D. Anderson Cancer Center
Eli Lilly and Company; BioMed Valley Discoveries, Inc

Recruiting

Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy

Metastatic Colorectal Cancer

United States
University of Southern California
National Cancer Institute (NCI)

Not yet recruiting

A2-ESO-1 TCR-Engineered T Cells for Relapsed/Refractory Advanced or Metastatic NY-ESO-1 Overexpression Positive Triple Negative Breast Cancer

Triple Negative Breast Cancer

United States
Beijing 302 Hospital
Wuhan Optics Valley Zhongyuan Pharmaceutical Co., Ltd., Hubei, China

Not yet recruiting

Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-1b)

Decompensated Cirrhosis

China
Capital Medical University

Recruiting

Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-1b) (PROTECT)

Reperfusion Injury | Acute Ischemic Stroke

China
Adam Kittai

Recruiting

Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome

Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Transformed B-Cell Non-Hodgkin Lymphoma | Refractory Transformed Non-Hodgkin Lymphoma | Refractory Transformed B-cell Non-Hodgkin Lymphoma | Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma | Recurrent Transformed... and other conditions

United States
Genfit

Recruiting

Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutation Cholangiocarcinoma

Cholangiocarcinoma

United States, Puerto Rico
QuantumLeap Healthcare Collaborative

Recruiting

PRE-I-SPY Phase I/Ib Oncology Platform Program (PRE-I-SPY-PI)

Solid Tumor | Metastatic Cancer | Metastatic Breast Cancer | Triple Negative Breast Cancer | HER2-positive Breast Cancer | Solid Tumor, Adult | Solid Carcinoma | HER2-positive Metastatic Breast Cancer | Progesterone Receptor-positive Breast Cancer | HER2-negative Breast Cancer | Estrogen Receptor Positive... and other conditions

United States
Biotheus Inc.

Recruiting

Clinical Study of PM1003 in Phase I/IIa Treatment of Advanced Malignant Solid Tumors

Advanced Solid Tumors

China
Biotheus Inc.

Recruiting

Phase I/IIa Study for PM1032 in the Treatment of Patients With Advanced Solid Tumors

Advanced Tumor

China
OrsoBio, Inc

Recruiting

Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity

Obesity | Healthy Subjects

New Zealand
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
Shanghai HyaMab Biotech Co.,Ltd.

Recruiting

PE0116 and PE0105 Injection in Treatment of Patients With Advanced Solid Tumor

Locally Advanced/Metastatic Solid Tumors

China
University of Southern California
National Cancer Institute (NCI)

Recruiting

Breast Cancer Survivorship Biorepository

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Invasive Breast Carcinoma

United States
Research Institute of Epidemiology, Microbiology...

Recruiting

Impact of A. Lumbricoides on Pulmonary Aspergillosis Development

Chronic Pulmonary Aspergillosis | COPD Exacerbation Acute | Ascaris Lumbricoides Infection

Uzbekistan
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Recruiting

A Phase 1b Study to Evaluate APL-1401 in Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States
Wugen, Inc.

Not yet recruiting

A Phase 1b Study of WU-NK-101 in Combination With Cetuximab

Squamous Cell Carcinoma of Head and Neck | Colorectal Cancer Metastatic
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Lisocabtagene Maraleucel, Nivolumab and Ibrutinib for the Treatment of Richter's Transformation

Richter Syndrome | Recurrent Transformed Chronic Lymphocytic Leukemia | Refractory Transformed Chronic Lymphocytic Leukemia

United States
In8bio Inc.

Recruiting

A Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed Glioblastoma

Glioblastoma

United States
Manchester University NHS Foundation Trust

Not yet recruiting

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study (INCAS)

Aspergillosis | Chronic Pulmonary Aspergillosis

Search clinical trials for: 1b

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