Search clinical trials for: APOE ε4

Total 92 results

Aristotle University Of Thessaloniki
Greek Alzheimer's Association and Related Disorders

Recruiting

Effects of Pomegranate Seed Oil and Mediterranean Diet on MCI

Mild Cognitive Impairment

Greece
University of Southern California

Not yet recruiting

Music-Based Interventions, Aging, Alzheimer's Disease

Anxiety | Social Behavior | Speech Perception
University of Arizona
National Institute on Aging (NIA); University of Southern California; Syneos... and other collaborators

Recruiting

Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease (REGEN-BRAIN©)

Neurodegenerative Diseases | Alzheimer Dementia | Late Onset Alzheimer Disease

United States
The Cleveland Clinic
National Institutes of Health (NIH); National Institute on Aging (NIA); University...

Recruiting

CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease) (CYCLE-AD)

Normal Cognition | High Intensity Exercise | Exercise Intervention

United States
Firalis SA

Recruiting

A Prospective, Monocentric Clinical Study for the Validation of in Vitro Diagnostic Tests Developed by Firalis (ApoDiag)

Genetic Health Risks

France
Shanghai University of Traditional Chinese Medicine
Shanghai Minimally Invasive Surgery Center

Not yet recruiting

Clinical Evaluation of Acupuncture Treatment on Alzheimer's Disease in APOE e4 Carriers and Non-Carriers

Cognitive Impairment | Alzheimer Disease

China
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Changes in Thinking Related to Aging and Cancer in Breast Cancer Survivors (TRAC) (TRAC)

Breast Cancer Survivors

United States
IRCCS Centro San Giovanni di Dio Fatebenefratelli

Recruiting

Targeting Default Mode Network Dysfunction in Persons at Risk of Alzheimer's Disease With Non-invasive Techniques (NEST4AD)

Alzheimer Disease

Italy
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; Fondation...

Recruiting

Circadian Rhythm and Other Factors in Memory Clinic Patients (CIRCAME)

Dementia

France
Istituto Auxologico Italiano

Recruiting

Exploring to Remediate Behavioral Disturbances of Spatial Cognition (BDSC-MCI)

Spatial Navigation

Italy
UNC Lineberger Comprehensive Cancer Center
AstraZeneca; Rgenix, Inc.

Recruiting

Abequolixron (RGX-104) and Durvalumab in Lung Cancer

Non-Small Cell Lung Cancer

United States
University of East Anglia
Quadram Institute Bioscience

Recruiting

DIetary plAnt Extracts, Colonic MicrObes, and Apoe geNetics Interactions stuDy (DIAMOND)

Alzheimer Disease

United Kingdom
Roskamp Institute Inc.
Boston University; United States Department of Defense; Palo Alto Veterans Institute...

Recruiting

Validating Gulf War Illness Blood Biomarkers

Gulf War Syndrome | Gulf War Illness

United States
University of Manchester
Manchester University NHS Foundation Trust; Great Ormond Street Hospital for... and other collaborators

Recruiting

Autologous Ex-vivo Gene Modified HSCT in MPSII

Mucopolysaccharidosis II

United Kingdom
University Hospital, Montpellier
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Sleep Impairment in Subjects at Risk of Developing Alzheimer's Disease (WAVE-APOE4)

Sleep Disorder | Cognitive Decline | Neuropathology
Azienda Ospedaliero-Universitaria Careggi
University of Florence; Fondazione Don Carlo Gnocchi Onlus; Scuola Superiore...

Recruiting

PRedicting the EVolution of SubjectIvE Cognitive Decline to Alzheimer's Disease With Machine Learning (PREVIEW)

Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline

Italy
Lexeo Therapeutics

Recruiting

Long-Term Follow-up of Gene Therapy for APOE4 Homozygote Alzheimer's Disease (LEADLTFU)

Alzheimer Disease

United States
National Taiwan Normal University

Recruiting

Exercise and Neurocognition in Adults Relative to ApoE Genotype

Aging | Exercise Training | Neurocognitive Function

Taiwan
National Taiwan Normal University

Recruiting

Multi-Domain Exercise and Memory in Adults Relative to ApoE Genotype: A fMRI Study

Aging | Exercise Training | Executive Function

Taiwan
Banner Health
Mayo Clinic

Recruiting

APOE in the Predisposition to, Protection From, and Prevention of Alzheimer's Disease

Alzheimer Disease

United States
University of Washington
National Institute on Aging (NIA)

Recruiting

Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain

Dementia | Alzheimer Disease

United States
National Taiwan University Hospital

Recruiting

Multimodal Biomarkers for Diagnosis and Prognosis in VCI (VCI)

Alzheimer Disease | Vascular Cognitive Impairment

Taiwan
Fondazione Don Carlo Gnocchi Onlus

Recruiting

Predictors of Better Outcomes After Severe Acquired Brain Injuries (FP-GCA)

Brain Injuries | Disorder of Consciousness

Italy
Columbia University
National Institute on Aging (NIA)

Recruiting

Information About Alzheimer's Disease for Latinos in New York City (IDEAL)

Alzheimer Disease

United States
Yu-Hsiang Wu
Vanderbilt University Medical Center; National Institute on Deafness and Other...

Recruiting

Hearing Aid and Individuals With Cognitive Disorders

Alzheimer Disease 2 Due to Apoe4 Isoform | Presbycusis, Bilateral

United States
National Taiwan University Hospital

Recruiting

Multimodal Biomarkers for Diagnosis and Prognosis in CAA (CAA)

Alzheimer Disease | Intracranial Hemorrhages | Cerebral Amyloid Angiopathy

Taiwan
University of North Carolina, Greensboro
National Institute on Aging (NIA); Wake Forest University Health Sciences

Recruiting

Physical Activity, Alzheimer's Disease and Cognition Relative to APOE Genotype (PAAD-2)

Healthy | Physical Activity | Dementia | Alzheimer Disease

United States
University of Rhode Island
Stuart Sinoff, MD; Peter J Snyder, MD; BayCare Health System

Recruiting

Atlas of Retinal Imaging in Alzheimer's Study (ARIAS)

Cognitive Change | Alzheimer Disease | Aging | Mild Cognitive Impairment | Mild Dementia

United States
Duke University
University of Edinburgh in Scotland; Tan Tock Seng Hospital in Singapore; Queens...

Recruiting

Retinal Imaging in Neurodegenerative Disease

Multiple Sclerosis | Parkinson's Disease | Traumatic Brain Injury | Down Syndrome | Mild Cognitive Impairment | Frontotemporal Dementia | Huntington Disease | Amyotrophic Lateral Sclerosis (ALS) | Alzheimer's Disease | Concussion | Post-Traumatic Stress Disorder | Neuro-Degenerative Disease | Lewy Body Dementia | Normal... and other conditions

United States
Douglas Scharre
Avid Radiopharmaceuticals; Mangurian Foundation

Recruiting

Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease

Parkinson's Disease | Alzheimer's Disease | Lewy Body Dementia

United States
Inspirna, Inc.

Recruiting

A Study of RGX-104 in Patients With Advanced Lung & Endometrial Cancer

Lung Cancer | Endometrial Cancer | Non-small Cell Lung Cancer Metastatic | Non-small Cell Carcinoma | Endometrial Cancer Recurrent | Lung Cancer Recurrent

United States
Banner Health

Recruiting

GeneMatch: A Program of the Alzheimer's Prevention Registry to Match Individuals to Studies Based on Apolipoprotein E (APOE) Genotype

Alzheimer Disease

United States
Alzheon Inc.

Enrolling by invitation

Long-term Extension of Phase 3 Study of ALZ- 801 in APOE4/4 Early AD Subjects (APOLLOE4-LTE)

Early Alzheimer's Disease

United States, Spain, Canada, Netherlands, Czechia, United Kingdom, France, Germany, Iceland
Alzheon Inc.
National Institute on Aging (NIA)

Active, not recruiting

An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects (APOLLOE4)

Early Alzheimer's Disease

United States, Spain, Canada, Netherlands, Czechia, United Kingdom, France, Germany, Iceland
Universidad de León
Consejo General de Colegios Oficiales de Enfermería España

Completed

Polymorphism of ApoE in Alzheimer's Disease: Genetic Study in Castile and Leon (Spain)

Alzheimer Disease

Spain
Pfizer

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Factor IX Gene Therapy With PF-06838435 in Adult Males With Moderately Severe to Severe Hemophilia B (BENEGENE-2)

Hemophilia B

Germany, United Kingdom, Canada, Australia, Taiwan, Japan, France, Turkey, Korea, Republic of, United States, Brazil, Greece, Saudi Arabia, Sweden
Mayo Clinic

Enrolling by invitation

Plasmapheresis Versus Plasma Infusion From Young APOE3 Homozygotes Into MCI APOE4 Homozygotes to Slow Disease Progression

Mild Cognitive Impairment

United States
Parc de Salut Mar
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Hospital...

Completed

Prevention of Cognitive Decline in ApoE4 Carriers With Subjective Cognitive Decline After EGCG and a Multimodal Intervention ((PENSA))

Alzheimer Disease | Cognitive Decline

Spain
University of Washington

Completed

APOE Genotype and Diet Influences on Alzheimer's Biomarkers

Alzheimer's Disease; Dementia

United States
Tammie L. S. Benzinger, MD, PhD

Withdrawn

Imaging of Brain Structural/Functional Connectivity and Amyloid and Tau Lesions in APOE4 Carriers. (Protocol_Z)

Alzheimer Disease

United States
Alzheon Inc.

Active, not recruiting

Biomarker Effects of ALZ-801 in APOE4 Carriers With Early Alzheimer's Disease

Early Alzheimer's Disease

Netherlands, Czechia
Wroclaw Medical University

Completed

Biomarkers of Recurrence and Progression in Non-muscle Invasive Bladder Cancer

Recurrence | Progression | Biomarkers | Bladder Cancer | Non-muscle Invasive Bladder Cancer | Cystoscopy

Poland
Memorial Sloan Kettering Cancer Center
City of Hope Medical Center; The New School for Social Research

Active, not recruiting

Cognition in Older Breast Cancer Survivors: Treatment Exposure, APOE and Smoking History

Breast Cancer Survivors

United States
University Hospital, Caen
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Multi-modal Neuroimaging in Alzheimer's Disease (IMAP+)

Alzheimer's Disease

France
Pennington Biomedical Research Center
Nutrition Obesity Research Center

Completed

Food Intake and Intra-Nasal Insulin for African American Adults (FIINAAL) (FIINAAL)

Insulin

United States
Lexeo Therapeutics
Weill Medical College of Cornell University; Alzheimer's Drug Discovery Foundation

Active, not recruiting

Gene Therapy for APOE4 Homozygote of Alzheimer's Disease

Alzheimer Disease | Early Onset Alzheimer Disease

United States
Miles Berger, MD PhD

Completed

Modulating ApoE Signalling to Reduce Brain Inflammation, deLirium and postopErative Cognitive Dysfunction (MARBLE)

Postoperative Delirium | Postoperative Cognitive Dysfunction

United States
Mayo Clinic
Spark Neuro Inc.

Enrolling by invitation

Development of an EEG Diagnostic for Alzheimer's Disease

Alzheimer Disease | Mild Cognitive Impairment | Dementia With Lewy Bodies | Normal Control APOE e4 Carriers and Noncarriers

United States
Medical College of Wisconsin
National Institute on Aging (NIA)

Completed

Network-Level Mechanisms for Preclinical Alzheimer's Disease Development

APOE 4

United States
National Taiwan Normal University

Completed

Acute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of AD

Alzheimer Disease 2 Due to Apoe4 Isoform

Taiwan

Search clinical trials for: APOE ε4

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Gambia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations