Search clinical trials for: APOE4 Homozygotes

Total 24 results

Lexeo Therapeutics
Weill Medical College of Cornell University; Alzheimer's Drug Discovery Foundation

Active, not recruiting

Gene Therapy for APOE4 Homozygote of Alzheimer's Disease

Alzheimer Disease | Early Onset Alzheimer Disease

United States
University Hospital, Caen
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Multi-modal Neuroimaging in Alzheimer's Disease (IMAP+)

Alzheimer's Disease

France
Avera McKennan Hospital & University Health Center

Completed

The Occurrence of the ApoE4 Allele in Agitated In-Patients With Late-Onset Alzheimer's Disease

Alzheimer's Disease | Agitation

United States
University of Kansas Medical Center
National Institute on Aging (NIA)

Completed

Dementia Risk and Dynamic Response to Exercise (DYNAMIC)

Healthy Aging | Alzheimer Disease 2 Due to Apoe4 Isoform

United States
National Taiwan Normal University

Completed

Acute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of AD

Alzheimer Disease 2 Due to Apoe4 Isoform

Taiwan
University Hospital, Caen
Institut National de la Santé Et de la Recherche Médicale, France

Unknown

Multi-modal Neuroimaging in Alzheimer's Disease (IMAP)

Alzheimer's Disease

France
University Hospital, Montpellier
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Sleep Impairment in Subjects at Risk of Developing Alzheimer's Disease (WAVE-APOE4)

Sleep Disorder | Cognitive Decline | Neuropathology
Alzheon Inc.

Active, not recruiting

Biomarker Effects of ALZ-801 in APOE4 Carriers With Early Alzheimer's Disease

Early Alzheimer's Disease

Netherlands, Czechia
University of Pennsylvania

Completed

Telephone Versus Videoconference Communication for Remote Genetic Disclosure in the APOE4 Trial (CONNECT4APOE)

Alzheimer Disease | Genetic Predisposition to Disease
JANSSEN Alzheimer Immunotherapy Research & Development...
Pfizer

Completed

Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Carrier)

Alzheimer's Disease

United States
Mayo Clinic

Enrolling by invitation

Plasmapheresis Versus Plasma Infusion From Young APOE3 Homozygotes Into MCI APOE4 Homozygotes to Slow Disease Progression

Mild Cognitive Impairment

United States
JANSSEN Alzheimer Immunotherapy Research & Development...
Pfizer

Completed

Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Non-Carrier)

Alzheimer's Disease

United States, Germany, Canada, Austria
Tammie L. S. Benzinger, MD, PhD

Withdrawn

Imaging of Brain Structural/Functional Connectivity and Amyloid and Tau Lesions in APOE4 Carriers. (Protocol_Z)

Alzheimer Disease

United States
Lexeo Therapeutics

Recruiting

Long-Term Follow-up of Gene Therapy for APOE4 Homozygote Alzheimer's Disease (LEADLTFU)

Alzheimer Disease

United States
Alzheon Inc.
National Institute on Aging (NIA)

Active, not recruiting

An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects (APOLLOE4)

Early Alzheimer's Disease

United States, Spain, Canada, Netherlands, Czechia, United Kingdom, France, Germany, Iceland
Parc de Salut Mar
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Hospital...

Completed

Prevention of Cognitive Decline in ApoE4 Carriers With Subjective Cognitive Decline After EGCG and a Multimodal Intervention ((PENSA))

Alzheimer Disease | Cognitive Decline

Spain
Wageningen University
Radboud University Medical Center

Completed

Efficacy of Fish Oil Supplementation on Cognition in MCI Patients and the Influence of the APOE4 Allele

Mild Cognitive Impairment

Netherlands
Alzheon Inc.

Enrolling by invitation

Long-term Extension of Phase 3 Study of ALZ- 801 in APOE4/4 Early AD Subjects (APOLLOE4-LTE)

Early Alzheimer's Disease

United States, Spain, Canada, Netherlands, Czechia, United Kingdom, France, Germany, Iceland
Yu-Hsiang Wu
Vanderbilt University Medical Center; National Institute on Deafness and Other...

Recruiting

Hearing Aid and Individuals With Cognitive Disorders

Alzheimer Disease 2 Due to Apoe4 Isoform | Presbycusis, Bilateral

United States
Novartis Pharmaceuticals
Amgen; Banner Alzheimer's Institute

Terminated

A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease (GS2)

Alzheimers Disease

Spain, United States, Belgium, Italy, Germany, Australia, Israel, Taiwan, Japan, Canada, Korea, Republic of, United Kingdom, France, China, Argentina, Finland, Singapore, Portugal, Chile, Mexico, Switzerland, Netherlands, Iceland, Puerto... and more
Novartis Pharmaceuticals
National Institute on Aging (NIA); Amgen; Banner Alzheimer's Institute

Terminated

A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease (GS1)

Alzheimers Disease

United States, Belgium, United Kingdom, Germany, Australia, Canada, Spain, Finland, Switzerland, Netherlands
Instituto de Investigación Sanitaria Aragón
Hospital Clínico Universitario Lozano Blesa; FEIRACO LACTEOS SL

Recruiting

Effects of UNICLA-A2 Dairy Products on Patients at High-risk of Colorectal Cancer Development

Colorectal Polyp

Spain
Acrotech Biopharma Inc.
Axis Clinicals Limited

Completed

Establish the PK of Belinostat in Patients With Wild-type, Heterozygous, and Homozygous UGT1A1*28 Genotypes

Solid Tumors | Hematological Malignancies

United States
Laval University

Completed

Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial Hypercholesterolemia (LA-PBMC)

Familial Hypercholesterolemia

Canada

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