Search clinical trials for: ATTRwt amyloidosis

Total 637 results

Steen Hvitfeldt Poulsen

Recruiting

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt) (DobATTR)

ATTR Amyloidosis Wild Type

Denmark
Steen Hvitfeldt Poulsen

Recruiting

Screening of ATTRwt in Patient With Advanced AV-Block Undergoing Pacemaker Implantation (ATTRAB)

Amyloid Cardiomyopathy | Block, AV

Denmark
Austin Neuromuscular Center
Alnylam Pharmaceuticals

Recruiting

Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy

Polyneuropathies | Transthyretin Amyloidosis | Wild-Type Transthyretin-Related (ATTR)Amyloidosis | Wild-Type Transthyretin Cardiac Amyloidosis | Wild Type ATTR Amyloidosis

United States
Alnylam Pharmaceuticals

Recruiting

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis) (ConTTRibute)

Transthyretin-Mediated Amyloidosis | ATTR Amyloidosis

Israel, Italy, Netherlands, Spain, United States, France, Denmark, Germany, Portugal, Brazil, Taiwan
Brigham and Women's Hospital
GlaxoSmithKline; Ionis Pharmaceuticals, Inc.

Withdrawn

The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the Heart

Amyloidosis
Helse Møre og Romsdal HF

Not yet recruiting

ATTR Cardiac Amyloidosis in a Selected Population

Carpal Tunnel Syndrome | Cardiac Amyloidosis | ATTR Amyloidosis Wild Type | ATTR Gene Mutation
Yongyong MA

Recruiting

Daratumumab/Daratumumab and Hyaluronidase-fihj in Combination With Pomalidomide and Dexamethasone for the Treatment of Patients With Newly Diagnosed AL Amyloidosis: a Prospective, Multicenter, Single-arm Study

Amyloid Light-chain Amyloidosis

China
Gérond'if

Not yet recruiting

Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure (ARNOLD)

Cardiac Amyloidosis

France
Leiden University Medical Center
The Dutch Brain Foundation (funding)

Not yet recruiting

Stimulating Amyloid Clearance in Cerebral Amyloid Angiopathy (Clear-Brain)

Cerebral Amyloid Angiopathy
Jeffrey Zonder

Not yet recruiting

DapagliFLOzin in Renal AL Amyloidosis (FLORAL) (FLORAL)

Renal AL Amyloidosis

United States
Peking University People's Hospital

Recruiting

Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients With MIDD

Monoclonal Gammopathy of Renal Significance

China
AstraZeneca

Recruiting

Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia (LOCUS)

Carpal Tunnel Syndrome | Amyloidosis | Polyneuropathy | Hereditary Transthyretin Amyloidosis

Russian Federation
Alnylam Pharmaceuticals

Recruiting

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy (cAPPricorn-1)

Cerebral Amyloid Angiopathy

Canada
Pfizer

Recruiting

Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

United States
IRCCS Policlinico S. Matteo

Recruiting

Promoting Diagnosis and Management of AL in Italy (ProDigALIty) (ProDigALIty)

AL Amyloidosis | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

Italy
Nanjing University School of Medicine

Recruiting

Daratumumab for Patients With Light Chain Amyloidosis

Light Chain (AL) Amyloidosis

China
Steen Hvitfeldt Poulsen

Recruiting

Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy (DobAttrAS)

Aortic Stenosis | Transthyretin Amyloid Cardiomyopathy

Denmark
Institut Mutualiste Montsouris

Recruiting

Orthopaedic Specimen Pathology and Early Diagnosis of ATTR Cardiopathy (ATTR-ORTHO) (ATTR-ORTHO)

Carpal Tunnel Syndrome | Knee Prosthesis | ATTR Amyloidosis | Cardiopathy | Hip Prosthesis | Lumbar Spine Stenosis

France
AstraZeneca

Recruiting

hATTR Polyneuropathy in Russia (PRIMER)

Hereditary Transthyretin Amyloidosis

Russian Federation
Tufts Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Screening for AL Amyloidosis in Smoldering Multiple Myeloma

Smoldering Multiple Myeloma

United States
Alnylam Pharmaceuticals

Recruiting

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Hereditary Amyloidosis, Transthyretin-Related | Asymptomatic Carrier State

France
AstraZeneca

Recruiting

OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis (OverTTuRe)

ATTR Amyloidosis

Spain, United States, Denmark, Japan, Sweden, United Kingdom
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Unclassified GENotypes of Autoinflammatory Diseases and AA Amyloidosis (IPHYGENI MAI)

Autoinflammatory Disease | AA Amyloidosis
John Paul II Hospital, Krakow

Recruiting

New Biomarkers and Plasma Prothrombotic Potential in Cardiac Transthyretin Amyloidosis

Transthyretin Amyloidosis

Poland
Jin Lu, MD

Recruiting

Bortezomib, Pomalidomide, Dexamethasone For Systemic AL Amyloidosis

Systemic Amyloidosis

China
AstraZeneca

Recruiting

Transthyretin Amyloidosis Cardiomyopathy in Patients With HFpEF in Russia (TETRAMER)

Transthyretin Amyloidosis Cardiomyopathy, Heart Failure With Preserved Ejection Fraction

Russian Federation
Mahidol University
Pfizer

Not yet recruiting

Thailand ATTR-CM Registry

Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Thailand
Algalarrondo Vincent
Bichat Hospital; Bioquantis

Recruiting

Artificial Intelligence to Assist the Echocardiographic Identification of Transthyretin Cardiac Amyloidosis (AI-ATTR-ECHO)

Transthyretin Cardiac Amyloidosis | Transthyretin Amyloid Cardiomyopathy | Amyloid Cardiomyopathy

France
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis) (LINKER-AL2)

Relapsed/Refractory Systemic Light Chain Amyloidosis
Steen Hvitfeldt Poulsen
Novo Nordisk A/S

Recruiting

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

Quality of Life | Transthyretin Amyloidosis | Transthyretin Amyloid Cardiomyopathy | Wild-Type Transthyretin-Related (ATTR)Amyloidosis

Denmark
Novo Nordisk A/S

Recruiting

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

United States, Netherlands, Germany, Canada, Czechia, France, Italy, Portugal, Spain
Medical University of Graz
Medical University Innsbruck

Recruiting

Association Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid Cardiomyopathy

Amyloid Cardiomyopathy | Wild Type ATTR Amyloidosis

Austria
Paolo Milani

Recruiting

NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis (NOTE-ATTR)

Amyloidosis | Amyloidosis Cardiac | ATTR Amyloidosis Wild Type

Italy
Assiut University

Not yet recruiting

Affection of Renal and Urinary System in IBD Patients

Nephrolithiasis, Glomerulonephritis, Amyloidosis,AKI, CKD, Tubuli Interstitial | Urinary System Disorders in IBD Patients
IRCCS Policlinico S. Matteo

Recruiting

A EUropean REgistry and Sample Sharing networK to Promote the Diagnosis and Management of Light Chain Amyloidosis (EUREKA) (EUREKA)

AL Amyloidosis

Germany, Italy, Spain, Switzerland, Netherlands
University Tunis El Manar

Recruiting

Cardiac Amyloidosis in HFpEF Tunisian Patients (Amy-Card)

Prevalence | Heart Failure With Preserved Ejection Fraction | Diagnosis | Cardiac Amyloidosis | Echocardiography | CMR | Bone Scintigraphy

Tunisia
Assistance Publique - Hôpitaux de Paris
Association Française Contre l'Amylose (association of patients and families...

Not yet recruiting

AMYLO-SHIATSU-ACUTE-CHRONIC (AMYLO-SHIATSU)

Cardiac Amyloidosis
AstraZeneca

Recruiting

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy (EPIC-ATTR)

Transthyretin Amyloid Cardiomyopathy

China
Jin Lu, MD

Recruiting

Optimize First-line Treatment for AL Amyloidosis With t (11; 14)

AL Amyloidosis | Amyloidosis; Systemic

China
Midwest Heart & Vascular Specialists

Recruiting

Amyloidosis Incidence in High-Risk Cardiac Device Patients

AL Amyloidosis | Amyloid | Cardiac Amyloidosis | Amyloidosis Cardiac | Systemic Amyloidosis | ATTR Amyloidosis Wild Type | Infiltrative Cardiomyopathy, Amyloid

United States
Alexion Pharmaceuticals, Inc.

Recruiting

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM (DepleTTR-CM)

Transthyretin Amyloid Cardiomyopathy

United States, Spain, United Kingdom, Norway, Israel, China, Korea, Republic of, Belgium, France, Germany, Italy, Japan, Australia, Argentina, Austria, Taiwan, Switzerland, Canada, Sweden, Poland, Denmark, Turkey, Brazil, Netherlands, G... and more
Assiut University

Not yet recruiting

Validation of Different Diagnostic Modalities in the Detection of Cardiac Amyloidosis Among Patients With "Red Flags"

Cardiac Amyloidosis
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving ABBV-383 as an Intravenous (IV) Infusion

Immunoglobulin Light Chain (AL) Amyloidosis

Japan, United States, Australia
Intellia Therapeutics
Regeneron Pharmaceuticals

Recruiting

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Australia, United Kingdom, New Zealand, Canada
University of Leipzig

Recruiting

Cardiac Amyloidosis Registry of University Hospital Leipzig

Cardiac Amyloidosis

Germany
Medical University of Vienna
Medical University of South Carolina; IRCCS Azienda Ospedaliero-Universitaria... and other collaborators

Recruiting

Aortic Stenosis and Cardiac Amyloidosis

Aortic Stenosis | Cardiac Amyloidosis

Austria, United Kingdom
Martin Dichgans

Recruiting

High Frequency Imaging in Cerebral Amyloid Angiopathy (HIFI-CAA)

Cerebral Amyloid Angiopathy

Germany
Philippe Debonnaire

Not yet recruiting

Early Diagnosis of Age-Linked CArdiac TransThyRetin Amyloidosis by Selective Screening in Spinal Stenosis Surgery (ALCATTRASS)

Transthyretin Amyloid Cardiomyopathy
Nexcella Inc.

Not yet recruiting

Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis (NEXICART-2)

Light Chain (AL) Amyloidosis

United States
Wake Forest University Health Sciences

Recruiting

CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study (CAPACITY)

Cardiac Amyloidosis

United States

Search clinical trials for: ATTRwt amyloidosis

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