Search clinical trials for: Abuse Potential

Total 6950 results

National Institute on Alcohol Abuse and Alcoholism...

Not yet recruiting

Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder

Alcohol Use Disorder

United States
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Not yet recruiting

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Alcohol-Related Disorders | Alcohol Use | Alcohol Use Disorder (AUD)

United States
Vanderbilt University Medical Center
National Institute on Drug Abuse (NIDA)

Recruiting

Low-dose Buccal Buprenorphine: Relative Abuse Potential and Analgesia

Pain | Analgesia | Abuse Opioids

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder

Cocaine Use Disorder

United States
University of Colorado, Boulder
National Institute on Drug Abuse (NIDA)

Recruiting

Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 1 (COBRA)

Cannabis | Electroencephalography | Memory

United States
University of Florida

Recruiting

The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults

Pain

United States
Michael Sofis
Dartmouth College

Recruiting

Examining Effects of Domain Specific Episodic Future Thinking on Cannabis Use

Tobacco Use | Marijuana Use | Alcohol Use, Unspecified | Marijuana Dependence

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Recruiting

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers (RVA Flavors)

Electronic Nicotine Delivery System Flavors

United States
Hunter College of City University of New York
National Institute on Drug Abuse (NIDA); University of Michigan

Recruiting

Expanding the Potential of Couples HIV Testing: Adjunct Modules to Reduce Drug Use Among Vulnerable Male Couples (4Us)

HIV Infections | Substance Use

United States
University of Santiago de Compostela

Recruiting

Role of the Dentist in the Control of the Alcoholic Habit in Patients With Potentially Malignant Oral Lesions (ALCODENT)

Alcohol Drinking | Oral Potentially Malignant Disorders

Spain
Harvard School of Public Health (HSPH)
National Institute on Drug Abuse (NIDA); National Institute on Alcohol Abuse... and other collaborators

Recruiting

Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women (SMARTT)

Antiretroviral Toxicity

United States, Puerto Rico
National Institute on Drug Abuse (NIDA)

Recruiting

Screening Protocol for the Evaluation of Potential Research Subjects

Addiction

United States
Indivior Inc.
National Institute on Drug Abuse (NIDA)

Completed

Study of Potential CYP3A4 Induction by INDV-2000 in Healthy Adults

Healthy

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study to Evaluate Abuse Potential of Istradefylline

Drug Abuse

United States
Azurity Pharmaceuticals

Completed

An Abuse Potential Study of Orally Administered HORIZANT in Healthy, Non-dependent, Recreational Drug Users

Abuse Potential

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Nicotine Delivery Rate and Its Abuse Potential: Impact of Menthol

Nicotine Dependence

United States
Azurity Pharmaceuticals

Completed

Evaluation of Abuse Potential of HORIZANT Taken Alone and With Oxycodone in Healthy, Nondependent Recreational Opioid Users

Abuse Potential

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Enhancing Medication-based Analgesia in Humans- STUDY 2

Pain | Cannabis | Opioid Use

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Nicotine's Potential Abuse With Menthol

Nicotine Dependence

United States
Viatris Specialty LLC

Completed

Evaluating the Abuse Potential of NEURONTIN® When Taken Orally in Healthy Non-drug Dependent Participants With Sedative Drug Abuse Experience

Abuse Potential

United States
Pop Test Oncology LLC
Baylor College of Medicine; Michael E. DeBakey VA Medical Center; Congressionally... and other collaborators

Completed

Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)

Potential Treatment for Alcohol Dependence-Alcohol Interaction

United States
Johns Hopkins University

Completed

Enhancing Medication-based Analgesia in Humans

Pain | Cannabis | Opioid Use, Unspecified

United States
Haisco-USA Pharmaceuticals, Inc.

Completed

Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users

General Anesthesia

United States
New York State Psychiatric Institute
University of Kentucky

Completed

A Study to Evaluate the Abuse Potential of Oxymorphone Compared to Other Mu Opioid Agonists.

Opioid Use Disorder

United States
Viatris Specialty LLC

Completed

Study Evaluating the Abuse Potential of NEURONTIN® in Healthy Non-drug Dependent, Recreational Opioid Users

Abuse Potential

United States
Viatris Specialty LLC

Completed

Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users

Abuse Potential

United States
Janssen Research & Development, LLC

Completed

A Study to Determine the Abuse Potential of Seltorexant Compared to Suvorexant and Zolpidem

Healthy Non-dependent, Recreational Sedative Users | Abuse Potential

United States
Koç University

Completed

The Effect of Child Abuse and Neglect Prevention Program on Awareness Levels and Child Abuse Potential of Pregnant Women

Child Abuse

Turkey
Jazz Pharmaceuticals

Completed

Abuse Potential of Sativex

Evaluation of Abuse Potential of Sativex

Canada
Ensysce Biosciences
Dr. Vince Clinical Research

Completed

A Study to Evaluate the Oral Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Recreational Drug Use

United States
Ensysce Biosciences

Completed

A Study to Evaluate the Intranasal Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Recreational Drug Use

United States
University of Michigan
National Institute on Drug Abuse (NIDA); University of Maryland

Completed

EEG/Event-related Brain Potential Risk Markers as Predictors and Outcomes of SUD Treatment in Adolescents

Alcohol Use Disorder

United States
Germans Trias i Pujol Hospital
Fundació Recerca Institut Germans Trias i Pujol; Istituto Superiore di Sanità

Active, not recruiting

Abuse Potential and Human Pharmacology of Methylone (METI/FIS/1)

Healthy Subjects | Substance Use

Spain
Tris Pharma, Inc.

Completed

Assessment of Abuse Potential of Cebranopadol in Humans

Human Abuse Potential

United States
Tris Pharma, Inc.

Completed

A Trial to Evaluate the Abuse Potential of 3 Doses of GRT6005 in Adult Non-dependent Recreational Opioid Users

Abuse, Drug

Canada
University of Wisconsin, Madison
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Testing Doxazosin to Treat Stress Mechanisms in Alcoholism

Alcoholism

United States
Baylor College of Medicine

Completed

Carisbamate as a Potential Treatment for Alcohol Dependence

Alcohol Dependence | Substance Abuse | Alcohol Abuse

United States
Trevi Therapeutics
Syneos Health

Completed

Oral Abuse Potential Study of Nalbuphine

Opioid Abuse | Nalbuphine

Canada
Eisai Inc.
Purdue Pharma LP

Completed

A Study to Determine the Abuse Potential of Single Oral Doses of Lemborexant Compared to Zolpidem, Suvorexant and Placebo in Healthy, Non-Dependent, Recreational Sedative Users

Insomnia Disorders

Canada
Eli Lilly and Company

Completed

A Study of the Abuse Potential of Lasmiditan in Participants Who Are Recreational Drug Users

Prescription Drug Abuse (Not Dependent) | Recreational Drug Use

United States
Charleston Laboratories, Inc

Completed

A Study in Opioid-Experienced, Non-Dependent Recreational Drug Users to Determine the Abuse Potential and Safety of CL-108 Tablets Administered Via the Oral Route

Pain | Nausea | Vomiting
Paion UK Ltd.
PRA Health Sciences

Completed

Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users

Abuse, Drug

United States
Idorsia Pharmaceuticals Ltd.

Completed

Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug Users

Healthy Recreational Drug Users

United States, Canada
Eisai Inc.

Completed

Abuse Potential of Single Doses of Lorcaserin in Healthy Recreational Polydrug Users

Healthy | Drug Abuse

Canada
University of Wisconsin, Madison
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Repurposing alpha1 Noradrenergic Antagonists for Alcoholism Treatment

Alcoholism

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

Assessment of Abuse Potential of Rapastinel in Humans

Human Abuse Potential

United States
Sun Pharma Advanced Research Company Limited

Completed

To Evaluate the Relative Abuse Potential of Hydrocodone Bitartrate and Acetaminophen

Healthy

Canada
Avekshan LLC

Completed

Study for Naltrexone on the Abuse Potential of Methylphenidate

Naltrexone | Methylphenidate Abuse

United States
Acura Pharmaceuticals Inc.
King Pharmaceuticals is now a wholly owned subsidiary of Pfizer

Completed

Study of the Relative Abuse Potential of Acurox Tablets in Non-Dependent Recreational Opioid Users

Opioid Abuse

United States

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