Search clinical trials for: Aldose Reductase Inhibitor

Total 67815 results

Applied Therapeutics, Inc.

Active, not recruiting

Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia

Classic Galactosemia

United States
Applied Therapeutics, Inc.

Active, not recruiting

Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy

Diabetic Cardiomyopathies

United States, France, Spain, Australia, Canada, United Kingdom, Germany, Czechia, Hong Kong, Poland
University of Utah
Kaiser Permanente

Not yet recruiting

A Tool to Help Patients With Muscle Symptoms After Taking a Statin Medication.

Cardiovascular Diseases | Hypercholesterolemia | Placebo Effect | Pharmacists | Hydroxymethylglutaryl-CoA Reductase Inhibitors
Incyte Corporation

Recruiting

A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics When Administered Orally to Healthy Adult Participants

Healthy Participants

United States
Assiut University

Not yet recruiting

Topical Simvastatin Versus Topical Steroid in Treatment of Alopecia Areata

Alopecia Areata

Egypt
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Novartis Pharmaceuticals

Not yet recruiting

Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction (V-ACCELERATE)

Plaque, Atherosclerotic
Assiut University

Not yet recruiting

Statins Role in Acute Ischemic Stroke (observation)

Stroke, Acute
Johns Hopkins University
American Heart Association

Not yet recruiting

Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet

Epilepsy | Dyslipidemia
University of Bologna

Not yet recruiting

Middle Term Effect of Red Yeast Rice on Plasma Lipids and Proteoma in Individuals With Suboptimal Cholesterolemia

Hypercholesterolemia

Italy
Kafrelsheikh University

Recruiting

Combining Use of Clopidogrel With Atorvastatin or Rosuvastatin in Patients With Large-vessel Ischemic Stroke

Ischemic Stroke

Egypt
Kafrelsheikh University

Recruiting

Concomitant Use of Clopidogrel With Atorvastatin or Rosuvastatin in Patients With Minor Stroke or TIA

Ischemic Stroke

Egypt
Jemincare

Not yet recruiting

Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

Solid Tumor, Adult
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

Effects of Inclisiran Combined With Statins on the Morphology of Coronary Vulnerable Plaques (EItoCVP)

Coronary Artery Disease
Mario Pérez Sayáns
Universidad de Murcia

Recruiting

Osteogenic Action of a Biphasic Bioceramic With Statin in a Third Molar Extraction Model (Galibone)

Bone Loss | Regenerative Inflammation

Spain
Hangzhou Sciwind Biosciences Co., Ltd.

Recruiting

A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin

Healthy Volunteers

China
Anhui Medical University

Recruiting

Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study

Cognitive Impairment | Intracranial Atherosclerosis | Cerebrovascular Event

China
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United Kingdom
Tianjin Medical University General Hospital

Recruiting

Evaluate the Efficacy and Safety of Atorvastatin Combined With Temozolomide in the Treatment of Glioblastoma

Glioblastoma, IDH-wildtype

China
Children's Mercy Hospital Kansas City
Indiana Clinical and Translational Sciences Institute

Recruiting

IMProving DRug Dosing and Outcomes for Single VEntricle Patients With Fontan Associated Liver Disease (IMPROVE-FALD)

Fontan Circulation

United States
Kirby Institute

Not yet recruiting

Optimising Metabolic Management for People With Human Immunodeficiency Virus (HIV) on Integrase Based Antiretroviral Therapy (ART) (OPTIMAR)

HIV Infections | Weight Gain
D. Walter Wray
US Department of Veterans Affairs

Recruiting

Novel Approaches for Improving Vascular Function in Veterans With HFpEF

Inflammation | HFpEF - Heart Failure With Preserved Ejection Fraction

United States
Zhujiang Hospital

Not yet recruiting

Effectiveness of Atorvastatin in Preventing Cerebrovascular Events After Flow Diverter Implantation

Efficacy Endpoint: no New Cerebrovascular Adverse Events Within 1 Year | Safety Endpoint: no New Moderate or Serious Adverse Events Within 1 Year | All-cause Mortality Events (Within 1 Year) | Incident Ischemic Stroke Events (Within 1 Year) | New Hemorrhagic Stroke Events (Within 1 Year) | New... and other conditions
Arab Contractors Medical Centre

Not yet recruiting

Colchicine Versus Beta-blockers, Angiotensin-converting Enzyme Inhibitors, and Statins for Prevention of Chemotherapy-Induced Cardiomyopathy (BASiC-CIC)

Chemotherapy Induced Systolic Dysfunction

Egypt
Boundless Bio

Recruiting

Study of the RNR Inhibitor BBI-825 in Subjects With Tumors With Resistance Gene Amplifications (STARMAP)

Solid Tumor

United States
Eccogene

Recruiting

ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy Participants

Type 2 Diabetes Mellitus

United States
Korea University Anam Hospital

Not yet recruiting

To Assess With Ezefeno Tab. in Patients With Dyslipidemia and T2DM (ENSEMBLE)

Dyslipidemias | T2DM (Type 2 Diabetes Mellitus)

Korea, Republic of
Novo Nordisk A/S

Recruiting

A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body Weight

Obesity

Canada
University of Louisville

Recruiting

Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) (ARTCAP)

Coronary Artery Disease | Atherosclerosis | Heart Attack

United States
Pfizer

Recruiting

A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes Mellitus (T2DM)

United States
Joyce Teng
Stanford University

Not yet recruiting

Topical Simvastatin for Treating Infantile Hemangioma (TSTIH)

Hemangioma Skin

United States
Peking University Third Hospital

Recruiting

Evaluation of the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Diabetic Patients

Diabetes

China
EMS

Not yet recruiting

Efficacy and Safety of the DTT106 in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia (AUSTRÁLIA)

Erectile Dysfunction | Prostatic Hyperplasia, Benign

Brazil
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Not yet recruiting

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins (PREVESTATGx)

Cardiovascular Diseases | Dyslipidemias | Statin Adverse Reaction | Pharmacogenic Myopathy

Spain
St. Olavs Hospital
Ullevaal University Hospital; Oslo University Hospital; University Hospital of... and other collaborators

Not yet recruiting

Prophylactic Treatment With Atorvastatin for Episodic Migraine. (EStatinMig)

Episodic Migraine
Suzhou Sanegene Bio Inc.

Not yet recruiting

A Study to Evaluate SGB-3403 in Healthy Volunteers and Subjects With Elevated Low-Density Lipoprotein Cholesterol (LDL-C)

Hyperlipidemias
Bio-innova Co., Ltd

Not yet recruiting

Dutasteride Soft Capsule 0.5 mg Relative to Avodart 0.5 mg Soft Capsule

Healthy Subjects
Yonsei University

Not yet recruiting

Randomized Comparison of Efficacy and Safety of High-intensity Rosuvastatin/Ezetimibe Combination Versus Treat-to-target Rosuvastatin Monotherapy for Patients With Peripheral Artery or Polyvascular Disease (CARE-PVD Trial)

Peripheral Artery Disease | Polyvascular Disease

Korea, Republic of
Obafemi Awolowo University Teaching Hospital
Open Philanthropy

Recruiting

ATORvastatin in Pulmonary TUBerculosis (ATORTUB)

Tuberculosis | Pulmonary Tuberculosis | Koch's Disease

Nigeria
Eli Lilly and Company

Recruiting

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

Healthy | Overweight | Obese

United States
Saint Vincent's Hospital, Korea

Recruiting

Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention (ALMIGHTY)

Coronary Artery Disease | Dyslipidemias | Primary Prevention

Korea, Republic of
International Bio service

Not yet recruiting

Bioequivalence Study of Simvastatin 40 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects

Healthy Subjects

China
OHSU Knight Cancer Institute
Oregon Health and Science University; Kuni Foundation

Recruiting

Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA Melanoma

Clinical Stage IIA Cutaneous Melanoma AJCC v8

United States
Yonsei University

Recruiting

Clinical Trial to Evaluate the Efficacy and Safety of Suvaro®OD Tablet in Patients With Dyslipidemia

Dyslipidemia

Korea, Republic of
Ain Shams University

Not yet recruiting

Ameliorating Contrast Induced Nephropathy After Coronary Angiography

Coronary Artery Disease | Nephropathy; Toxic, Drugs
Region Stockholm
Amgen

Not yet recruiting

Studies to Gain Insight How the Drugs PCSK9-inhibitors and Statins Affect Cholesterol and Bile Acid Metabolism

Acute Metabolic Effects of Evolocumab and Atorvastatin
Xuanwu Hospital, Beijing

Not yet recruiting

Short-term Effect of PCSK9 Inhibitor in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke
Eli Lilly and Company
Loxo Oncology, Inc.

Not yet recruiting

A Drug-Drug Interaction Study of LY3537982 on Midazolam, Digoxin, and Rosuvastatin in Healthy Participants

Healthy

United States
Beni-Suef University

Not yet recruiting

Clinical Effects of New Approach on Patients With Non-alcoholic Steatohepatitis

Non-alcoholic Steatohepatitis

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