Search clinical trials for: Ampullary neoplasms

Total 107182 results

Cancer Institute and Hospital, Chinese Academy...

Recruiting

Quantitative Nodal Burden as a Determinant Identifying Ampullary Adenocarcinoma Patients Benefiting From Adjuvant Chemotherapy

Chemotherapy Effect | Ampullary Adenoma

China
Asian Institute of Gastroenterology, India

Not yet recruiting

Endoscopic Resection of Papillary Adenomas; a Novel Treatment Algorithm to Prevent Recurrence - a Pilot-study (ERASE)

Ampullary Adenoma
Revolution Medicines, Inc.

Recruiting

Study of RMC-6291 in Combination With RMC-6236 in Participants With Advanced KRAS G12C Mutant Solid Tumors

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma | Non-Small Cell Lung Cancer (NSCLC)

United States, Puerto Rico
Fondazione Poliambulanza Istituto Ospedaliero
Associazione Italiana per la Ricerca sul Cancro

Recruiting

The ADAPTA Study: ADjuvant chemotherAPy After Curative Intent resecTion of Ampullary Cancer. (ADAPTA)

Ampullary Adenocarcinoma

Italy
Kuban State Medical University
City Clinical Oncology Hospital No 1; State Budget Public Health Institution...

Not yet recruiting

Reconstruction of the Pelvic Floor and Perineal Wound After Rectal ELAPE

Rectum Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Surufatinib Combined With Toripalimab and AG Regiments for First-line Treatment of Unresectable or Relapsing Metastatic Ampullary Carcinoma

Ampullary Carcinoma
Dartmouth-Hitchcock Medical Center

Recruiting

Individualized Dose Escalation of 5-FU for Gastrointestinal Cancer

Colorectal Cancer | Small Bowel Cancer | Appendix Cancer | Esophagus Cancer | Ampullary Cancer

United States
Azienda Unità Sanitaria Locale della Romagna

Recruiting

Efficacy and Safety of Endoscopic Papillectomy in the Treatment of Ampullary Neoplasms. (PaNETh)

Ampulla of Vater Adenoma | Ampullary Cancer | Ampulla of Vater Cancer | Ampullary Adenoma

Italy
Compass Therapeutics

Recruiting

A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)

Cholangiocarcinoma | Biliary Tract Cancer | Gall Bladder Cancer | Ampullary Cancer

United States
University of California, Irvine

Recruiting

Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

Hepatocellular Carcinoma | Pancreatic Cancer | Cholangiocarcinoma | Pancreatic Carcinoma | Hepatobiliary Cancer | Ampullary Cancer

United States
Revolution Medicines, Inc.

Recruiting

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | Non-Small Cell Lung Cancer (NSCLC) | Colorectal Cancer (CRC)

United States, Italy, Spain, Malaysia, Korea, Republic of, France, Australia, Thailand, Taiwan, Poland, Singapore, Czechia, Serbia
Shanghai Zhongshan Hospital

Recruiting

CSP vs EMR for >6mm Superficial Non-ampullary Duodenal Tumors (CSP; EMR)

Duodenal Tumor

China
University Hospital, Lille
Ministry of Health, France

Recruiting

Efficacy and Safety of TPIAT for Resectable Adenocarcinoma of the Pancreas Region at High Risk of Postoperative Fistula (TPIAT-01)

Adenocarcinoma of the Pancreas | Ampullary Adenocarcinoma | Adenocarcinoma of the Duodenum

France
Cedars-Sinai Medical Center
National Cancer Institute (NCI)

Recruiting

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Gastrointestinal Neoplasms | Stomach Cancer | Small Intestine Cancer | Rectal Cancer | Neuroendocrine Tumor | Bile Duct Cancer | Colon Cancer | Pancreas Cancer | Anal Cancer | Liver Cancer | Biliary Tract Cancer | Peritoneal Cancer | Carcinoid Tumor | Gallbladder Cancer | Cancer Pain | Carcinoid Tumor of the Small Bowel | Visceral... and other conditions

United States
Ruijin Hospital
Intuitive Surgical

Recruiting

Robotic Versus Open Pancreaticoduodenectomy for Pancreatic and Periampullary Tumors (PORTAL)

Pancreatic Adenocarcinoma | Chronic Pancreatitis | Ampullary Adenocarcinoma | Cholangiocarcinoma, Extrahepatic | Pancreatic Cysts | Pancreatic Endocrine Tumors | Duodenal Adenocarcinoma

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Incyte Corporation

Recruiting

INCMGA00012 in Patients With Previously Treated Unresectable or Metastatic Adenosquamous Pancreatic or Ampullary Cancer

Pancreatic Cancer Metastatic | Pancreatic Cancer Non-resectable

United States
George Zogopoulos

Recruiting

Quebec Pancreas Cancer Study (QPCS)

Pancreatic Cancer | Bile Duct Cancer | Pancreas Cancer | Gallbladder Cancer | Pancreas Neoplasm | Familial Pancreatic Cancer | Duodenal Cancer | Hereditary Cancer | Pancreas Cyst | Ampullary Cancer | Pancreatic Precancerous Condition

Canada
Federation Francophone de Cancerologie Digestive

Recruiting

Survival and Description of Care for Patients With Degenerate Vaterian Ampulloma (AMPULLOMA)

Ampullary Adenocarcinoma

France
Washington University School of Medicine

Active, not recruiting

Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy

Pancreatic Cancer | Pancreatitis | Pancreas Cancer | Duodenal Cancer | Ampullary Cancer | Pancreas Neuroendocrine Tumor | Distal Extrahepatic Cholangiocarcinoma

United States
Redx Pharma Plc
Merck Sharp & Dohme LLC

Completed

A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2) (KEYNOTE-E86)

Advanced Solid Tumours

United Kingdom, Australia
Imperial College London
Royal Free Hospital NHS Foundation Trust; Royal Surrey County Hospital NHS...

Completed

MicroRNAs as Bile-based Biomarkers in Pancreaticobiliary Cancers (MIRABILE)

Pancreatic Cancer | Cholangiocarcinoma | Biliary Stricture | Gallstone Disease | Ampullary Cancer

United Kingdom
Seagen Inc.

Active, not recruiting

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Urologic Neoplasms | Uterine Cervical Neoplasms | Uterine Neoplasms | Carcinoma, Non-Small-Cell Lung | Biliary Tract Neoplasms | HER2 Mutations Breast Neoplasms

United States, United Kingdom, Spain, Korea, Republic of, Italy, Belgium, Germany, Japan, Netherlands, Poland
University Hospital Plymouth NHS Trust
University of Plymouth

Completed

Recurrence After Whipple's (RAW) Study

Pancreatic Cancer | Surgery | Bile Duct Cancer | Pancreatic Ductal Adenocarcinoma | Survivorship | Cholangiocarcinoma, Extrahepatic | Cancer Recurrence | Recurrent Cancer | Pancreatic Ductal Carcinoma | Cholangiocarcinoma of the Extrahepatic Bile Duct | Ampullary Cancer | Cholangiocarcinoma Resectable | Cancer... and other conditions

Spain, United Kingdom, Australia, Austria, Italy, Mexico, Sudan, Pakistan
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC

Cholangiocarcinoma | Biliary Tract Cancer | Gallbladder Cancer

Korea, Republic of, United States, Taiwan, China, Argentina, Australia, Brazil, Chile, France, Germany, Italy, Japan, Poland, Spain, United Kingdom
Affiliated Hospital of Guangdong Medical University

Enrolling by invitation

Modified vs Conventional Blumgart Anastomosis of LPD for the Effects of Pancreatic Fistula of Periampullary Carcinoma

Bile Duct Cancer | Pancreas Cancer | Ampullary Cancer | Duodenum Cancer

China
pharmaand GmbH

Terminated

A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes (LODESTAR)

Solid Tumor

United States
Professor Michael Bourke

Completed

Endoscopic Characteristics of Duodenal and Ampullary Lesions (DUO/AMP-LST)

Duodenal Diseases

Australia
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Enrolling by invitation

Gene Expression Profile of Resected Pancreatic and Ampullary Adenocarcinoma at Favorable Prognosis

Resectable Pancreatic Adenocarcinoma

Italy
NuCana plc

Terminated

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Biliary Tract Cancer

Canada, United States, Spain, Hungary, Korea, Republic of, United Kingdom, Czechia, Germany, Russian Federation, Australia, France, Taiwan, Ukraine, Italy, Turkey
Dartmouth-Hitchcock Medical Center

Completed

Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy

Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Small Bowel Cancer | Appendix Cancer | Ampullary Cancer

United States
The Christie NHS Foundation Trust

Completed

ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract Cancers (ABC-08)

Cholangiocarcinoma | Biliary Tract Cancer | Gallbladder Cancer | Ampullary Cancer

United Kingdom
First People's Hospital of Hangzhou

Completed

EP Combined With RFA for Ampullary Neoplasms With Intraductal Biliary Extension

Ampullary Adenomas

China
AbGenomics B.V Taiwan Branch

Terminated

A Study of AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary Cancer

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Biliary Cancer

United States, Taiwan
Bing Hu

Completed

Endobiliary RFA for Unresectable Malignant Biliary Strictures

Cholangiocarcinoma | Ampullary Carcinoma

China
Campus Bio-Medico University
Azienda Ospedaliero, Universitaria Pisana; Medical University of Silesia; Humanitas...

Completed

Margin Status After Pancreaticoduodenectomy for Cancer

Pancreatic Cancer | Cholangiocarcinoma | Ampullary Cancer
The Christie NHS Foundation Trust
Cancer Research UK

Completed

Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers (ABC06)

Cholangiocarcinoma | Biliary Tract Cancer | Gallbladder Cancer | Ampullary Cancer

United Kingdom
Yonsei University

Unknown

Effectiveness of Prophylactic Antibiotics to Prevent Post Endoscopic Retrograde Cholangio Pancreatography Bacteremia in Biliary Obstruction Patient

Klatskin Tumor | Biliary Obstructive Disease Such as Choledocholithiasis | Benign Biliary Stricture | Peri-ampullary Cancer | Bile Duct Cancer Resectable

Korea, Republic of
Kliniken Ludwigsburg-Bietigheim gGmbH

Unknown

Endoscopic Resection of Non-ampullary Duodenal Adenomas: Endoscopic Mucosal Resection (EMR) vs. Endoscopic Full-thickness Resection With the 'Duodenal Full-thickness Resection Device' (dFTRD) (DUO-RESECT)

Duodenal Adenoma

Germany
Arcispedale Santa Maria Nuova-IRCCS

Completed

Endoscopic Papillectomy for Ampullary Adenomas (Papillectomy)

Familial Adenomatous Polyposis | Ampullary Adenoma
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary Cancer

Pancreatic Cancer | Small Intestine Cancer | Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer | Periampullary Adenocarcinoma

United States
Weill Medical College of Cornell University

Unknown

Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders

Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Cholangitis | Barrett's Esophagus | Gallstones | Choledocholithiasis | Bile Leak | Obstructive Jaundice | Duodenal Cancer | Pancreatic Pseudocysts | Ampullary Cancer | Biliary Strictures | Recurrent Pancreatitis | Bile Duct... and other conditions

United States
Weill Medical College of Cornell University

Unknown

T-EUS for Gastrointestinal Disorders: A Multicenter Registry (EUSERCPReg)

Pancreatic Cancer | Cholangiocarcinoma | Bile Duct Cancer | Chronic Pancreatitis | Biliary Stricture | Biliary Obstruction | Ampullary Cancer | Stent Obstruction | Proximal Duct Stricture | Distal Duct Stricture | Biliary Sphincter Stenosis | Impacted Stones | Peri-ampullary Diverticula | Altered Anatomy

United States, Brazil
Genzyme, a Sanofi Company

Completed

Vandetanib Gemcitabine Or Placebo Plus Gemcitabine Or Vandetanib Monotherapy In Advanced Biliary Tract Cancer (VANGOGH)

Biliary Tract Cancer | Gallbladder Cancer | Ampullary Carcinoma | Cancer Of The Extrahepatic Bile Duct

Italy
Ajou University School of Medicine

Completed

Loop-tipped Guidewire in Selective Biliary Cannulation

Pancreatic Cancer | Bile Duct Cancer | Choledocholithiasis | Ampullary Tumor

Korea, Republic of
GEM Hospital & Research Center

Completed

Pancreatic Head and Peri-ampullary Cancer Laparoscopic vs Open Surgical Treatment Trial (PLOT) (PLOT)

Cholangio Carcinoma | Adenocarcinoma of Head of Pancreas | Duodenal Adenocarcinoma | Carcinoma of Ampulla of Vater

India
Washington University School of Medicine

Completed

A Feasibility Phase II Study in the Treatment of Resected Cholangiocarcinoma, Gallbladder, Pancreatic and Ampullary Cancers

Pancreatic Cancer | Gallbladder Cancer | Ampullary Cancer | Cholangiocarcinoma Cancer

United States
307 Hospital of PLA
Changhai Hospital; The Affiliated Nanjing Drum Tower Hospital of Nanjing University...

Unknown

Radioactive Stents for Treatment of Unresectable Biliary Tract Cancer

Intrahepatic Cholangiocarcinoma | Biliary Obstruction | Cholangiocarcinoma of the Extrahepatic Bile Duct | Ampullary Carcinoma

China
King Chulalongkorn Memorial Hospital

Completed

Dual Focus NBI and pCLE in FAP Related Duodenal Adenoma (PIVI)

Complication of Diagnostic Procedure | Adverse Effect of Diagnostic Agents, Subsequent Encounter

Thailand
Baki Topal

Withdrawn

Reduced Intra-operative Blood Loss in Pancreaticoduodenectomy for Pancreatic or Peri-ampullary Tumors; Monocentric Trial on Standard Open Versus Minimally Invasive Surgery

Surgery | Pancreatic Tumour | Peri-ampullary Tumour | Blood Loss

Belgium
Baki Topal
University Hospital, Antwerp; General Hospital Groeninge; Université Catholique... and other collaborators

Completed

Reduced Pancreatic Fistula Rate Following Pancreaticoduodenectomy: Trial on Pancreaticogastrostomy Versus Pancreaticojejunostomy

Tumors

Belgium

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