Search clinical trials for: Amyloid Transthyretin Systemic Amyloidosis (ATTR)

Total 7595 results

Yale University
Alnylam Pharmaceuticals Inc

Not yet recruiting

Evaluation of a Claims-based Algorithm for the Identification of Transthyretin-mediated Amyloidosis (ATTR) Amyloidosis in Medical Records

Transthyretin Amyloidosis

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Clinical Study of ATTR-CM

Transthyroxine Amyloidosis Cardiomyopathy

China
University Hospital, Antwerp

Not yet recruiting

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) in Patients With Idiopathic Peripheral Neuropathy

Heart Failure | Amyloidosis | Amyloidosis Cardiac | Cardiomyopathies, Secondary | Amyloid Polyneuropathy | Cardiomyopathy Non-Dilated

Belgium
University of Tennessee Graduate School of Medicine

Completed

124I-p5+14 Injection Safety in Subjects With Systemic Amyloidosis

Systemic Amyloidosis

United States
Institut Mutualiste Montsouris

Recruiting

Orthopaedic Specimen Pathology and Early Diagnosis of ATTR Cardiopathy (ATTR-ORTHO) (ATTR-ORTHO)

Carpal Tunnel Syndrome | Knee Prosthesis | ATTR Amyloidosis | Cardiopathy | Hip Prosthesis | Lumbar Spine Stenosis

France
AstraZeneca

Recruiting

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy (EPIC-ATTR)

Transthyretin Amyloid Cardiomyopathy

China
Alnylam Pharmaceuticals

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALN-TTRSC04 in Healthy Subjects

Transthyretin-Mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects

TTR-mediated Amyloidosis

United Kingdom
IRCCS Policlinico S. Matteo

Recruiting

The Italian Transthyretin Amyloidosis Web-Network (ITA-WebNet)

ATTR Amyloidosis

Italy
University Hospital, Toulouse

Recruiting

Prevalence and Significance of ATTR Aortic Valve Amyloidosis in Degenerative Aortic Stenosis (RACAMYL)

Amyloidosis

France
Pfizer

Completed

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Transthyretin (TTR) Amyloid Cardiomyopathy

United States, Taiwan, Canada, Belgium, Australia, Czechia, Sweden, Spain, Italy, Hong Kong, Germany, Netherlands, United Kingdom, France, Japan, Argentina, Brazil
Eidos Therapeutics, a BridgeBio company

Active, not recruiting

Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

Amyloid Cardiomyopathy, Transthyretin-Related

United States, Spain, Australia, Canada, Italy, Netherlands, Ireland, New Zealand, Belgium, Israel, Greece, Korea, Republic of, Czechia, Brazil, Denmark, Portugal, United Kingdom
Paolo Milani

Recruiting

NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis (NOTE-ATTR)

Amyloidosis | Amyloidosis Cardiac | ATTR Amyloidosis Wild Type

Italy
Eidos Therapeutics, a BridgeBio company

Completed

Study of AG10 in Amyloid Cardiomyopathy

Familial ATTR-CM (ATTRm-CM, or FAC) | Wild-type ATTR-CM (ATTRwt-CM)

United States
Austin Neuromuscular Center
Alnylam Pharmaceuticals

Recruiting

Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy

Polyneuropathies | Transthyretin Amyloidosis | Wild-Type Transthyretin-Related (ATTR)Amyloidosis | Wild-Type Transthyretin Cardiac Amyloidosis | Wild Type ATTR Amyloidosis

United States
Neurimmune AG

Completed

First-in-Human Study of NI006 in Patients With Amyloid Transthyretin Cardiomyopathy

Amyloid Transthyretin Cardiomyopathy

Germany, France, Netherlands, Spain
Pfizer

Recruiting

Vyndaqel Capsules Special Investigation (ATTR-CM)

Transthyretin (TTR) Amyloid Cardiomyopathy

Japan
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-TTR01 in Transthyretin (TTR) Amyloidosis

Transthyretin Mediated Amyloidosis (ATTR)

United Kingdom, France, Portugal, Sweden
Umeå University

Completed

Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis (Dox/Urso)

Transthyretin Amyloidosis | Cardiomyopathy

Sweden
Pfizer

Completed

Safety And Efficacy Evaluation Of Fx-1006A In Subjects With Transthyretin Amyloidosis

ATTR-PN

United States, Germany, Argentina, Brazil, France, Italy, Portugal, Sweden
The Christ Hospital
The Cleveland Clinic; Ohio State University

Recruiting

ATTR-Cardiomyopathy Stabilization Following Tafamidis Therapy

Transthyretin Amyloidosis

United States
Attralus, Inc.

Active, not recruiting

A Study to Evaluate Organ Level Uptake Repeatability of 124I AT-01 in Subjects With Systemic Amyloidosis (AT01-001)

Amyloidosis

United States
Pfizer

Terminated

Global Prevalence of ATTR-CM in Participants With HFpEF

Heart Failure With Preserved Ejection Fraction | Transthyretin Amyloid Cardiomyopathy

Spain, United States, Japan, Canada, France, Italy, Poland, United Kingdom
Mahidol University
Pfizer

Not yet recruiting

Thailand ATTR-CM Registry

Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Thailand
Oncology Institute of Southern Switzerland
University of Kiel; Ente Ospedaliero Cantonale, Bellinzona

Completed

Prevalence of Wild Type ATTR

Wild-type Transthyretin Amyloidosis

Switzerland
Pfizer

Completed

Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy

ATTR-CM | TTR-CM

United States
Alnylam Pharmaceuticals

Active, not recruiting

APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Australia, Brazil, Bulgaria, France, Italy, Japan, Mexico, Netherlands, Taiwan, United Kingdom, Belgium, Czechia, Denmark, New Zealand, Sweden, Korea, Republic of, Argentina, Chile, Hong Kong, Portugal
Ionis Pharmaceuticals, Inc.
AstraZeneca

Active, not recruiting

The CARDIO-TTRansform Scintigraphy Sub-study

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

United States, Spain
University of Texas Southwestern Medical Center

Recruiting

Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation

Transthyretin Cardiac Amyloidosis

United States
University of Leipzig

Active, not recruiting

Native T1 CMR Imaging for Diagnosis of Cardiac Amyloidosis (CMR for CA)

Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure With Preserved Ejection Fraction | Hypertrophy, Left Ventricular | Heart Failure NYHA Class IV | Cardiac Amyloidosis | Heart Failure With Mid Range Ejection Fraction

Germany
Columbia University
Attralus, Inc.

Recruiting

Evuzamitide in PET/CT to Measure Potential Therapeutic Response in ATTR

Transthyretin Amyloidosis

United States
Steen Hvitfeldt Poulsen

Recruiting

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt) (DobATTR)

ATTR Amyloidosis Wild Type

Denmark
Yale University
Pfizer

Recruiting

Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR Cardiomyopathy

Cardiomyopathies, Primary

United States
University of Texas Southwestern Medical Center
Mid America Heart Institute

Withdrawn

Targeted Testing for ATTR Among Aortic Stenosis Patients-Pilot

Aortic Valve Stenosis | Cardiac Amyloidosis
Eidos Therapeutics, a BridgeBio company

Completed

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy (ATTRibute-CM)

Heart Diseases | Amyloidosis | Cardiomyopathies | Transthyretin Amyloidosis | Amyloid Cardiomyopathy

United States, Netherlands, Ireland, Canada, Italy, Spain, Belgium, New Zealand, Israel, Australia, Portugal, Brazil, Poland, Czechia, Denmark, Greece, Korea, Republic of, United Kingdom
CENTOGENE GmbH Rostock

Completed

Screening for the Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR FAP) (TRAP2-1)

Neuropathic Pain | Orthostatic Hypotension | Cardiac Failure | Gastrointestinal Disorders | Polyneuropathy, Amyloid

Spain, Austria, Hungary, North Macedonia, Poland, Serbia
Steen Hvitfeldt Poulsen

Recruiting

Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery (CACTuS2)

Transthyretin Amyloidosis | Transthyretin Cardiac Amyloidosis | Wild-Type Transthyretin-Related (ATTR)Amyloidosis

Denmark
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of Acoramidis (AG10) in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
Assistance Publique - Hôpitaux de Paris
Institut Curie

Recruiting

Rhabdoid Tumors Cellular Architecture by Single-cell Analyses (InnovRT-2) (InnovRT-2)

ATRT

France
AstraZeneca

Recruiting

OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis (OverTTuRe)

ATTR Amyloidosis

United Kingdom, United States, Denmark, Japan
Charite University, Berlin, Germany
Deutsches Herzzentrum Berlin, Klinik für Innere Medizin - Kardiologie; Klinik...

Active, not recruiting

Screening for Amyloidosis Before Aortic Valve Elective Replacement (SAVER)

Aortic Valve Stenosis | Amyloidosis

Germany
Ionis Pharmaceuticals, Inc.

Completed

NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

United States, Spain, Taiwan, Italy, Germany, Argentina, Australia, Brazil, Canada, Cyprus, France, Greece, New Zealand, Portugal, Sweden, Turkey
Prothena Biosciences Limited

Terminated

A Study of PRX004 in Subjects With Amyloid Transthyretin (ATTR) Amyloidosis

Amyloidogenic Transthyretin (ATTR) Amyloidosis

United States, Spain, Sweden, Portugal
Ionis Pharmaceuticals, Inc.
AstraZeneca

Active, not recruiting

CARDIO-TTRansform Magnetic Resonance Imaging (MRI) Sub-study

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

United States, United Kingdom, Italy, Spain
Virginia Commonwealth University

Not yet recruiting

Southeastern ATTR Amyloidosis Consortium: SEATTRAC Family Registry

Amyloidosis, Hereditary

United States
Ionis Pharmaceuticals, Inc.

Approved for marketing

ATTR Expanded Access Program (EAP) by Ionis

Amyloidosis, Hereditary
Medical University of Graz
Medical University Innsbruck

Recruiting

Association Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid Cardiomyopathy

Amyloid Cardiomyopathy | Wild Type ATTR Amyloidosis

Austria
Algalarrondo Vincent
Bichat Hospital; Bioquantis

Recruiting

Artificial Intelligence to Assist the Echocardiographic Identification of Transthyretin Cardiac Amyloidosis (AI-ATTR-ECHO)

Transthyretin Cardiac Amyloidosis | Transthyretin Amyloid Cardiomyopathy | Amyloid Cardiomyopathy

France
University Hospital Inselspital, Berne

Active, not recruiting

ATTR Amyloidosis in Elderly Patients With Aortic Stenosis

Aortic Stenosis Symptomatic | Amyloidosis Cardiac

Switzerland
Assistance Publique - Hôpitaux de Paris
Institut Curie; Sainte Anne hospital

Completed

Finding New Targets by Proteomic Approaches (InnovRT1) (InnovRT1)

ATRT

France

Search clinical trials for: Amyloid Transthyretin Systemic Amyloidosis (ATTR)

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