Search clinical trials for: Antigens, CD19

Total 748 results

Bambino Gesù Hospital and Research Institute

Active, not recruiting

Anti-CD19 CAR T Cells in Pediatric Patients Affected by Relapsed/Refractory CD19+ ALL and NHL

CD19-ALL | CD19-LNH

Italy
Centre Georges Francois Leclerc
AstraZeneca

Active, not recruiting

Study Evaluating the Efficacy of a Double Immunotherapy Combined With Olaparib in Patients With Solid Cancers and Carriers of Homologous Recombination Repair Genes After Olaparib Treatment (GUIDE2REPAIR)

Immunotherapy

France
AstraZeneca

Active, not recruiting

Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer (NILE)

Metastatic Urothelial Cancer | Unresectable Locally Advanced Urothelial Cancer

United States, Italy, Spain, Canada, Hungary, Poland, Argentina, Thailand, Vietnam, Turkey, Korea, Republic of, Brazil, Czechia, India, Japan, Philippines, Russian Federation, China, Taiwan, Israel, Australia, Bulgaria
Canadian Cancer Trials Group
AstraZeneca

Active, not recruiting

Durvalumab With or Without Tremelimumab in Advanced Incurable Solid Malignancies Given With or Without Standard Chemotherapy Regimens

Solid Malignancies

Canada
Bioeq GmbH

Completed

A Double-blind Study to Compare the Efficacy, Safety, and Immunogenicity of the Proposed Biosimilar Ustekinumab FYB202 to Stelara® in Patients With Moderate-to-Severe Plaque Psoriasis (VESPUCCI)

Plaque Psoriasis

Poland, Estonia, Ukraine, Georgia
Merck Sharp & Dohme LLC

Completed

A Phase 1/Phase 2 Study of Polyvalent Pneumococcal Conjugate Vaccine (V116) in Adults (V116-001)

Pneumonia, Pneumococcal

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study on the Management of Combination Anti-HIV Drug Therapy in HIV-Positive Children With Prior Treatment

HIV Infections

United States, Puerto Rico
Charite University, Berlin, Germany
Boehringer Ingelheim

Completed

Ketamine-Induced Brain Changes and Their Modulation by Lamotrigine

Emotions

Germany
University of Maryland, Baltimore
Food and Drug Administration (FDA)

Completed

Lamotrigine Bioequivalence

Epilepsy

United States
Masonic Cancer Center, University of Minnesota

Withdrawn

Erlotinib, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB-Stage IVA Cervical Cancer

Cervical Cancer

United States
Karin Skov
AstraZeneca; University of Aarhus

Unknown

Danish Hypertension Prevention Project - DHYPP

Hypertension

Denmark
Vanderbilt University

Completed

The RAS, Fibrinolysis and Cardiopulmonary Bypass

Coronary Artery Disease | Inflammation | Cardiopulmonary Bypass | Fibrinolysis | Angiotensin Receptor Blockers | Angiotensin Converting Enzyme

United States
Biomedis International Ltd.

Unknown

Recurrent Stroke Prevention Clinical Outcome Study (RESPECTS)

Stroke | Hypertension | Blood Pressure

Japan
The First Affiliated Hospital with Nanjing Medical...

Recruiting

The Study of the Combination of Thiotepa and Pomalidomide for the Treatment of Relapsed/Refractory Primary Central Nervous System Lymphoma Patients.

Relapsed or Refractory (R/R) Primary Central Nervous System Lymphoma

China
Kafrelsheikh University

Not yet recruiting

Combination of Recombinant Bacterial ACE2 Receptors -Like Enzyme of B38-CAP and Isotretinoin Could be Promising Treatment for COVID-19 Infection- and Its Inflammatory Complications

COVID
Centre Leon Berard
National Cancer Institute, France

Recruiting

Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment (MOST plus)

Malignant Solid Neoplasms

France
Emergent BioSolutions
National Institutes of Health (NIH)

Completed

Safety and Pharmacokinetics Study of Anthrax Immune Globulin Intravenous (AIGIV)

Anthrax

United States
Weill Medical College of Cornell University
Janssen Scientific Affairs, LLC

Active, not recruiting

Phase I Trial of Apalutamide Plus Abiraterone Acetate, Docetaxel, and Prednisone in Patients With mCRPC

Prostate Cancer Metastatic

United States
GWT-TUD GmbH

Completed

ASTRAL- a Clinical Study to Assess the Efficacy and Toxicity of High-dose Chemotherapy

Lymphoma, B-Cell | Lymphoma, T-Cell | Aggressive Non-hodgkin Lymphoma (aNHL)

Germany
International Extranodal Lymphoma Study Group (IELSG)

Active, not recruiting

New Combination of Chemoimmunotherapy for Systemic B-cell Lymphoma With Central Nervous System Involvement

Diffuse Large B-cell Lymphoma

Netherlands, United Kingdom, Italy, Czechia
University of Chicago

Completed

A Double-blind Randomized Placebo Controlled Clinical Trial Evaluating Effect of Chlorhexidine Gluconate 2% Cloth vs Placebo Cloth Baths on the Incidence of Central Line-Associated Blood Stream Infections in Outpatient Hematopoietic Stem Cell Transplant Patients

Stem Cell Transplant Complications

United States
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Efficacy of Ustekinumab Followed by Abatacept for the Treatment of Psoriasis Vulgaris (PAUSE)

Psoriasis

United States, Canada
Boehringer Ingelheim

Completed

An Open-label, Non-randomized, Single-arm Study to Investigate the Mechanism(s) by Which Nevirapine Increases Plasma HDL in HIV+ Subjects

HIV Infections | Metabolism, Lipids

Netherlands, United Kingdom
Emory University

Withdrawn

Safety and Efficacy Study of Correcting Hyperglycemia in Patients With Diabetes Having Out-patient Surgery

Type 1 Diabetes | Type 2 Diabetes

United States
Johns Hopkins Bloomberg School of Public Health
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Extended Infant Post-exposure Prophylaxis With Antiretrovirals to Reduce Postnatal HIV Transmission

HIV Infections

Malawi
French National Agency for Research on AIDS and...

Completed

Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa

HIV Infections | Tuberculosis

South Africa
Seoul National University Hospital

Unknown

The Impact of Vitamin on the Clinical Course in Cases Infected by Novel H1N1 Influenza Virus A

H1N1 Influenza

Korea, Republic of
Herlev Hospital

Unknown

Pulse Wave Velocity, Pulse Wave Morphology and Blocking of the Reninangiotensin System in Patients With Chronic Kidney Disease

Cardiovascular Diseases | Kidney Failure, Chronic

Denmark
National Cancer Institute (NCI)

Suspended

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Unresectable Triple-Negative Breast Carcinoma | Locally Advanced Triple-Negative Breast Carcinoma

United States
Emergent BioSolutions

Completed

Study in Healthy Volunteers Evaluating Safety and Pharmacokinetics of Zika Virus Immune Globulin (ZIKV-IG)

Zika Virus Infection | Zika Virus Disease

Canada
University College, London
National University Hospital, Singapore; Singapore Clinical Research Institute...

Completed

Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for Drug-sensitive Tuberculosis (TRUNCATE-TB)

Tuberculosis, Pulmonary

Singapore, Uganda, Thailand, Indonesia, Philippines, India
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test Whether Rifampicin Influences the Amount of BI 894416 in the Blood

Healthy

Germany
Dent Neuroscience Research Center
University at Buffalo

Completed

Study of Lamotrigine to Treat Ménière's Disease

Meniere's Disease | Ménière's Vertigo | Vertigo, Intermittent | Vertigo, Aural

United States
National Institute of Allergy and Infectious Diseases...

Withdrawn

Three Month Course of Anti-HIV Medications for People Recently Infected With HIV

HIV Infections
Merck Sharp & Dohme LLC

Completed

Safety and Tolerability of MK-5478 in Participants With Hypertension (5478-001)

Hypertension
HealthPartners Institute
Sanofi; International Diabetes Center at Park Nicollet

Completed

Hospital Insulin Protocol Aims for Glucose Control in Corticosteroid-induced Hyperglycemia

Hyperglycemia

United States
Cairo University

Completed

Effect of SLC30A8 rs13266634 Genetic Polymorphism on Zinc Supplementation and Glycemic Control in Egyptian Patients With Type 2 Diabetes Mellitus (SLC30A8)

Diabetes Mellitus, Type II

Egypt
CymaBay Therapeutics, Inc.

Completed

Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout Patients

Gout

United States, Canada, Georgia
University of Illinois at Chicago
GlaxoSmithKline

Completed

Lamotrigine Monotherapy in Pediatric Bipolar Disorder

Bipolar Disorder

United States
Pfizer

Completed

Study Assessing the Effect of Medications to Prevent Fever on Prevenar 13®

Pneumococcal Vaccines

Poland
Centocor, Inc.

Completed

A Study of the Safety and Efficacy of Ustekinumab (CNTO 1275) in Participants With Crohn's Disease

Crohn Disease

United States, Canada, Belgium
Boehringer Ingelheim

Completed

Quality of Life and Changes in Metabolism of Lipids and Glucose After Switching to a Nevirapine-based Regimen in HIV+ Patients

HIV Infections | Quality of Life

Italy
Eli Lilly and Company

Completed

Local Registration Trial in China Humalog Mix 50

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

China
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine and Zidovudine, Given Separately and Together, in HIV-1 Infected Patients Who Have No Symptoms of the Disease

HIV Infections

United States
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Anhui Provincial Hospital

Not yet recruiting

UTAA09 Injection in the Treatment of Relapsed/Refractory Hematolymphatic Malignancies.

CD19-positive Relapsed or Refractory B-cell Malignancies

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Exploratory Clinical Study of CD19-targeted CAR-T and CAR-DC in the Treatment of Relapsed and Refractory B-cell Lymphoma

Relapsed and Refractory B-cell Lymphoma

China
The Second Affiliated Hospital of Henan University...
First Affiliated Hospital of Wenzhou Medical University; Second Affiliated... and other collaborators

Unknown

Anti-CD19/CD22 Bispecific CAR-T Cell Therapy for CD19-positive ALL

CD19-positive ALL

China
Wuhan Union Hospital, China

Not yet recruiting

CD19/BCMA HLA-independent TCR-T Cell Therapy for Refractory/Moderate-to-severe Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Sana Biotechnology

Recruiting

Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM) (GLEAM)

Systemic Lupus Erythematosus | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Lupus Erythematosus | SLE (Systemic Lupus) | Granulomatous Polyangiitis

United States
Anhui Provincial Hospital

Recruiting

QH103 Cell Injection for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

B-cell Acute Lymphoblastic Leukemia

China

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