Search clinical trials for: Aortic Stenosis

Total 5146 results

The Royal Wolverhampton Hospitals NHS Trust

Completed

Novel Echocardiographic and Invasive Haemodynamic Measurements in the Assessment of Patients Low Flow Low Gradient Aortic Stenosis Undergoing TAVI (LFLG)

Cardiovascular Abnormalities

United Kingdom
Niguarda Hospital

Completed

Aortic Stenosis With COmplex PCI (ASCOP) Features Retrospective Registry on Contemporary Management and Outcomes (ASCOP)

Coronary Artery Disease | Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement | Angioplasty, Balloon, Coronary

Italy
Artivion Inc.
Duke Clinical Research Institute

Terminated

PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Failure

United States
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); Brigham and Women's Hospital

Active, not recruiting

The Impact of Exercise-Induced Cardiac Remodeling on Myocardial Efficiency

Cardiomyopathy, Hypertrophic

United States
LianBio LLC

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM

Obstructive Hypertrophic Cardiomyopathy

China
IHF GmbH - Institut für Herzinfarktforschung
Yale University; Boston Scientific Group

Active, not recruiting

accuRate Evaluation of Benefit With Optimal Medical Treatment With or Without Transcatheter Valve Repair of PARADOXical Low Flow Low Gradient Aortic Stenosis (REBOOT-PARADOX)

Aortic Valve Stenosis

Germany
French Cardiology Society
Pfizer; Henri Mondor University Hospital

Active, not recruiting

Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement. (AMYLOCARTESIAN)

Aortic Valve Stenosis | Amyloidosis | Aging | Heart Disease

France
Erasmus Medical Center
Dutch Heart Foundation

Active, not recruiting

Cardiac Imaging in Adults With Congenital Aortic Stenosis (CAS)

Congenital Aortic Stenosis

Netherlands
Edwards Lifesciences

Completed

PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - XT Intermediate and High Risk (PII A)

Symptomatic Severe Aortic Stenosis

United States, Canada
JOTEC GmbH

Active, not recruiting

Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP) (ASCEND)

Aortic Valve Disease

United States, Spain, United Kingdom, Germany, Italy
Corcym S.r.l

Terminated

Safety and Effectiveness Study of Perceval S Valve for Extended CE Mark (CAVALIER)

Aortic Valve Replacement

Belgium, Germany, Netherlands, France, Austria, Poland, Switzerland, United Kingdom
Bristol-Myers Squibb

Active, not recruiting

A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM

Hypertrophic Cardiomyopathy | Non-obstructive Hypertrophic Cardiomyopathy | Obstructive Hypertrophic Cardiomyopathy

Denmark, United States, Belgium, Czechia, France, Germany, Israel, Italy, Netherlands, Poland, Portugal, Spain, United Kingdom
Corcym S.r.l

Completed

Clinical Investigation of the Freedom SOLO Stentless Heart Valve

Heart Valve Diseases

Netherlands, Belgium, Germany, Austria, France, Italy, Portugal, Switzerland
Corcym S.r.l

Terminated

Perceval Sutureless Implant Versus Standard-Aortic Valve Replacement (PERSIST-AVR)

Aortic Stenosis | Aortic Valve Disease

Israel, Netherlands, France, United States, Spain, Canada, Italy, Austria, Germany, Belgium, Chile, United Kingdom
Corcym S.r.l

Active, not recruiting

PERCEVAL S Valve Clinical Study for Chinese Registration (PERFECT)

Aortic Valve Stenosis | Aortic Valve Disease

China
Corcym S.r.l

Terminated

Sorin Universal REgistry on Aortic Valve Replacement (SURE-AVR)

Aortic Stenosis | Aortic Valve Disease

Belgium, France, Spain, Israel, United Kingdom, Australia, United States, Netherlands, Germany, Italy, Singapore, Switzerland, Austria, Bulgaria, Canada, Czechia, Slovakia
Dokuz Eylul University

Completed

The Effect of Education and Follow-up Program in Patients Undergoing TAVI

Aortic Stenosis | Nursing Caries

Turkey
Fondazione Policlinico Universitario Agostino Gemelli...

Enrolling by invitation

CT-evaluation of Coronary Ostia Height After Surgical Aortic Valve Replacement. (CORONATE)

Aortic Valve Stenosis | Heart Valve Diseases | Aortic Regurgitation | Aortic Valve Insufficiency | Aortic Stenosis, Severe | Regurgitation, Aortic | Stenoses, Aortic | Coronary; Obstruction | Valve Disease, Aortic

Italy
Cytokinetics

Enrolling by invitation

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM (FOREST-HCM)

Symptomatic Hypertrophic Cardiomyopathy (HCM)

United States, France, Israel, Spain, United Kingdom, Italy, Poland, Hungary, Denmark, Netherlands, Germany, Czechia, Portugal
AorticLab Srl
Meditrial Europe Ltd.

Completed

NAUTILUS CE-mark Trial of the FLOWer Cerebral Embolic Protection Device (NAUTILUS)

Aortic Valve Stenosis | Intracranial Embolism and Thrombosis

Italy, Belgium
Abbott Medical Devices

Active, not recruiting

Portico NG Approval Study

Symptomatic Severe Aortic Stenosis

United States, Australia, Denmark, Italy, United Kingdom
Catharina Ziekenhuis Eindhoven

Active, not recruiting

Stress Aortic Valve Index for Assessing Risk in Aortic Valve Stenosis Patients (SAVI-AoS)

Aortic Valve Stenosis

Denmark, Netherlands, United States
Radboud University Medical Center
Medtronic

Completed

Upper Extremity Versus Lower Extremity Accessory Access Sites During Transcatheter Aortic Valve Implantation (TAVIXS)

Aortic Valve Stenosis

Netherlands
Erik Debing

Completed

Prevalence of Carotid Artery Stenosis and Abdominal Aortic Aneurysms in Brussels: a Population-based Screening Study.

Abdominal Aortic Aneurysm | Carotid Artery Stenosis | Epidemiology

Belgium
Abbott Medical Devices

Completed

Portico Valve-in-Valve Retrospective Registry

Aortic Stenosis | Aortic Valve Stenosis | Aortic Insufficiency | Aortic Valve Failure

Denmark, United Kingdom, Germany, Australia
Spanish Society of Cardiology
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III

Active, not recruiting

Dapagliflozin After Transcatheter Aortic Valve Implantation (DapaTAVI)

Aortic Stenosis | Transcatether Aortic Valve Implantation

Spain
Joshua Kanter

Active, not recruiting

Radiation-Free Heart Catheterization Using MRI

Aortic Stenosis | Atrial Septal Defect | Aortic Coarctation | Patent Ductus Arteriosus | Cardiomyopathy | Post Heart Transplant Catheter Procedure

United States
Maatschap Cardiologie Zwolle
Medtronic

Active, not recruiting

The TransCatheter Valve and Vessels Trial (TCW)

CABG | Aortic Stenosis | Fractional Flow Reserve | PCI | Multi Vessel Coronary Artery Disease | TAVI

Netherlands, France, Spain, Denmark, Austria, Poland, Portugal, Greece, Germany, Slovakia
Bristol-Myers Squibb

Completed

Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER (PIONEER-OLE)

Hypertrophic Cardiomyopathy

United States
Anteris Technologies Ltd.

Active, not recruiting

DurAVR™ THV System: First-In-Human Study

Aortic Valve Calcification | Severe Aortic Valve Stenosis | Symptomatic Aortic Stenosis

Georgia
Anteris Technologies Ltd.

Active, not recruiting

Use of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility Study (DurAVR™ EFS)

Aortic Stenosis | Aortic Valve Calcification | Severe Aortic Valve Stenosis | Symptomatic Aortic Stenosis

United States
Fudan University

Completed

Megestrol Acetate Plus Rosuvastatin in Young Women With Atypical Endometrial Hyperplasia

Atypical Endometrial Hyperplasia

China
Radboud University Medical Center

Active, not recruiting

Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI (APPOSE)

Aortic Valve Stenosis | Aortic Valve Insufficiency | Transcatheter Aortic Valve Replacement | Hemodynamic Monitoring | Acquired Von Willebrand Disease | Heyde's Syndrome

Netherlands
Hangzhou Valgen Medtech Co., Ltd

Active, not recruiting

Feasibility Study of the DragonFire for Hypertrophic Obstructive Cardiomyopathy

Obstructive Hypertrophic Cardiomyopathy

China
National University of Ireland, Galway, Ireland
Karolinska University Hospital; Galway University Hospitals; Kerckhoff Heart... and other collaborators

Enrolling by invitation

Feasibility, Safety, and Effectiveness of the ACURATE neo2 Transcatheter Heart Valve for Severe Bicuspid Aortic Stenosis (Neo2BAV)

Aortic Stenosis | Transcatheter Aortic Valve Replacement | Bicuspid Aortic Valve | Transcatheter Aortic Valve Implantation

Sweden, Ireland, Germany
Edwards Lifesciences

Active, not recruiting

ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE) (COMMENCE)

Heart Failure | Aortic Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Stenosis

United States, Canada, Poland
Boston Scientific Corporation

Active, not recruiting

ACURATE neo2™ Post Market Clinical Follow up Study

Aortic Valve Stenosis | Aortic Diseases | Aortic Valve Calcification

Netherlands, Denmark, United Kingdom, Spain, Italy, Switzerland, Sweden, Germany
University Hospital, Montpellier
Edwards Lifesciences

Completed

TAVI Without Balloon Predilatation (of the Aortic Valve ) SAPIEN 3 (DIRECTAVI)

Aortic Valve Stenosis

France
Braile Biomedica Ind. Com. e Repr. Ltda.

Active, not recruiting

Transfemoral Implant of Inovare® Transcatheter Valve

Aortic Valve Stenosis

Brazil
Medtronic Cardiovascular

Terminated

Medtronic Evolut™ EXPAND TAVR I Feasibility Study

Aortic Valve Stenosis

United States, New Zealand, Israel, Canada, Australia
Cytokinetics

Completed

Dose-finding Study to Evaluate the Safety, Tolerability, PK, and PD of CK-3773274 in Adults With HCM (REDWOOD-HCM)

Hypertrophic Cardiomyopathy (HCM)

United States, Spain, Italy, Netherlands
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias

Hypertrophic Cardiomyopathy (HCM) | Long QT Syndrome (LQTS) | Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) | Inherited Cardiac Arrythmias | Brugada Syndrome (BrS) | Early Repolarization Syndrome (ERS) | Arrhythmogenic Cardiomyopathy (AC, ARVD/C) | Dilated Cardiomyopathy (DCM) | Muscular... and other conditions

United States
Cardiawave SA
QbD Clinical

Active, not recruiting

VALVOSOFT® Pivotal Study

Aortic Valve Stenosis | Aortic Valve Calcification

France, Netherlands, Germany
MultiplAI Health Limited
Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia

Enrolling by invitation

Whole Blood Transcriptomic Signal According to Coronary Atherosclerotic Plaque Burden Assessed by CT Angiography (CORPLAQ-TRAIT)

Coronary Stenosis | Atherosclerotic Plaque | Aortic Calcification | Calcific Coronary Arteriosclerosis | Coronary Plaque

Argentina
Ya-Wei Xu

Completed

Prognostic Significance of CMD Assessed by IMR in HCM Patients (caIMR-HCM)

Coronary Cicrovascular Dysfunction | Hypertrophic Cardiomyopathy Patients
Cardiawave SA

Completed

Valvosoft First-In-Man Study in Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

France, Netherlands
Cytokinetics
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Completed

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM (SEQUOIA-HCM) (SEQUOIA-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, France, Spain, Portugal, Germany, China, United Kingdom, Israel, Netherlands, Denmark, Czechia, Hungary, Italy, Poland
Cardiawave SA

Active, not recruiting

Valvosoft First-In-Human Study in Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

Serbia
Foldax, Inc

Active, not recruiting

Clinical Investigation for the Foldax Tria Aortic Heart Valve- India

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Insufficiency | Aortic Valve Calcification

India
Aarhus University Hospital Skejby

Completed

Pressure Gradient vs. Flow Relationships in Patients With Symptomatic Valvular Aortic Stenosis (PREFLOW)

Aortic Valve Stenosis

Denmark

Search clinical trials for: Aortic Stenosis

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