Search clinical trials for: Arginine synthesis

Total 9955 results

Sunshine Lake Pharma Co., Ltd.

Completed

Effects of Rifampicin and Probenecid On The Pharmacokinetic Profile Of Rongliflozin In Healthy Subjects

Type 2 Diabetes Mellitus

China
Queen Mary University of London
Hoffmann-La Roche; Polaris Group

Withdrawn

Study in Patients With Tumours Requiring Arginine to Assess ADI-PEG 20 With Atezolizumab, Pemetrexed and Carboplatin (iTRAP)

Carcinoma, Non-Small-Cell Lung
National Institutes of Health Clinical Center (CC)

Completed

Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia

Sickle Cell Anemia

United States
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Endothelial Hyperpolarization in Humans

Hyperlipidemia

United States
Lars Nannestad Jorgensen

Completed

Effects of Oral Supplementation of Arginine, Zinc and Vitamin C on Collagen Synthesis in Inguinal Hernia Patients

Inguinal Hernia

Denmark
The Hospital for Sick Children

Completed

Arginine Synthesis in Healthy Adult Humans

Healthy

Canada
University of Nottingham

Unknown

Dysfunction of Nutritive Blood Flow as a Determinant of Anabolic Resistance With Age; the Role of Amino Acids in Modulating Muscle Metabolism (Ajinomoto1A)

Old Age (Focus; Not a Recognized Condition)

United Kingdom
Boston Medical Center

Completed

Ganciclovir Plus Arginine Butyrate in Treating Patients With Cancer or Lymphoproliferative Disorders Associated With the Epstein Barr Virus

Lymphoma | Leukemia | Small Intestine Cancer | Precancerous Condition

United States, Italy, Germany, France
University Hospital, Grenoble

Completed

Role of Epoxy-eicosatrienoic Acids in Post-occlusive Hyperemia and Thermal Hyperemia (EETY)

Healthy Volunteers

France
HemaQuest Pharmaceuticals Inc.
Boston University

Terminated

Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies

EBV Lymphomas | Lympho-proliferative Diseases

United States
HemaQuest Pharmaceuticals Inc.

Terminated

Study of HQK-1004 and Valganciclovir to Treat Epstein-Barr Virus (EBV) - Positive Lymphoid Malignancies or Lymphoproliferative Disorders

Lymphoproliferative Disorders | Lymphoid Malignancies

United States
Regional Hospital Holstebro

Completed

Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls

Hypertension
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

ORal Antibiotics In Acute Mesenteric Ischemia (ORIAMI)

Acute Mesenteric Ischemia

France
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Advanced KRAS G12D Mutant Solid Tumors

China
Ivan de Kouchkovsky, MD

Not yet recruiting

Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) MRI as a Response Monitoring Tool to Neoadjuvant Abiraterone

Prostate Cancer | High Risk Prostate Carcinoma

United States
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study Comparing BL-B01D1 With Platinum Based Chemotherapy in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Primus Pharmaceuticals
Sun Valley Arthritis Center

Recruiting

Effect of Metaxalone 640 mg (M640) on Truck Driving Ability and Cognition Compared to Other Skeletal Muscle Relaxants

Cognitive Impairment

United States
Indonesia University
Universitas Padjadjaran; Fakultas Kedokteran Universitas Indonesia; Institut... and other collaborators

Not yet recruiting

The Effect of Anthocyanin Intake From Purple Sweet Potato in Cerebral Small Vessel Disease

Cerebral Small Vessel Diseases
AstraZeneca

Not yet recruiting

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer (EvoPAR-BR01)

Advanced Breast Cancer

Canada
Modern Biosciences Ltd

Not yet recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients

Obesity | Atypical Endometrial Hyperplasia | Endometrial Neoplasms | Progesterone Resistance

China
Shanghai JMT-Bio Inc.

Not yet recruiting

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Local Advanced or Metastatic NSCLC
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
University of Missouri-Columbia
Gilead Sciences

Recruiting

Accelerated ART Initiation for PWHIV Who Are Out of Care (ACCELERATE)

HIV Infections | ART | Noncompliance, Patient

United States
University College, London
Washington University School of Medicine; University of Washington; Alzheimer... and other collaborators

Not yet recruiting

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK (NIO-SILK)

Alzheimer Disease | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
Egymedicalpedia

Not yet recruiting

Evaluation of TWEAK in Plaque Psoriasis and Psoriatic Arthritis Patients

Plaque Psoriasis

Egypt
Mỹ Đức Hospital

Not yet recruiting

Letrozole-stimulated Cycle Strategy Versus Artificial Cycle Strategy (LETSACT)

Hormone Replacement Therapy | Embryo Transfer | Letrozole | Irregular Menstruation
Mayo Clinic

Recruiting

Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment Prostate Cancer

Prostate Adenocarcinoma | Oligometastatic Prostate Carcinoma

United States
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
Andrea DeCensi
Herbert Irving Comprehensive Cancer Center; Breast Cancer Research Foundation; Istituto Europeo di Oncologia and other collaborators

Not yet recruiting

Babytam vs Babyexe in Post-menopausal Women at High Risk for Breast Cancer. (BabyTears)

Breast Cancer

Italy
University of Alabama at Birmingham

Not yet recruiting

DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC

Non Small Cell Lung Cancer

United States
Tufts University
Colgate Palmolive

Not yet recruiting

Dry Mouth Toothpaste Study - Comparing Two Toothpastes With Arginine

Xerostomia

United States
Dana-Farber Cancer Institute
Eli Lilly and Company

Not yet recruiting

ALPINE: Maintenance Letrozole/Abemaciclib vs Pembrolizumab

Endometrial Cancer | Recurrent Endometrial Cancer | TP53

United States
Medical College of Wisconsin

Not yet recruiting

Molecular Analyses to Identify Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

Breast Cancer

United States
University Hospital, Toulouse

Not yet recruiting

Efficacy of Injectable Gentamicin in Hereditary Ichthyosis (GENTIC)

Ichthyosis

France
PMV Pharmaceuticals, Inc

Recruiting

A Study to Investigate the Effects of Itraconazole on the Pharmacokinetics of PC14586 in Healthy Participants

Healthy Volunteers

United States
Celgene

Not yet recruiting

A Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Drug Levels of Golcadomide (BMS-986369) in Healthy Participants

Healthy Volunteers

United States
First Affiliated Hospital of Zhejiang University

Not yet recruiting

A Phase III Study Comparing the Efficacy of VHAG and Traditional Chemotherapy Regimens in Newly Diagnosed ETP-ALL

ETP-ALL

China
Atea Pharmaceuticals, Inc.

Not yet recruiting

Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/Ruzasvir

Healthy Volunteer Study

Canada
The Fourth Affiliated Hospital of Zhejiang University...

Recruiting

Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's Disease

Parkinson Disease

China
Hospices Civils de Lyon

Not yet recruiting

Efficacy and Tolerance of Abacavir/Lamivudine Treatment in Patients With Systemic Lupus Erythematosus (PENCIL)

Systemic Lupus Erythematosus

France
The Affiliated Hospital of Qingdao University

Recruiting

Preoperative Neoadjuvant Immunotherapy Combined With Chemotherapy for Stage Ⅲ Unresectable Non-small Cell Lung Cancer (PILOT)

Non-small-cell Lung Cancer (NSCLC)

China
AstraZeneca

Recruiting

A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants

Healthy Participants

United States
Hospital de Clinicas de Porto Alegre

Recruiting

Use of Letrozole for Ectopic Pregnancy (EcZOL)

Ectopic Pregnancy

Brazil
Qilu Hospital of Shandong University

Not yet recruiting

Efficacy and Safety of Bismuth Quadruple Therapy Containing Cefuroxime and Tetracycline as First-line Therapy for Eradicating Helicobacter Pylori in Patients Allergic to Penicillin

Helicobacter Pylori Infection

China
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Screen-and-treat Strategy for Vaginal Flora Abnormalities in Pregnant Women at High Risk of Preterm Birth (AUTOP2)

Bacterial Vaginosis | Premature Delivery | Vaginal Dysbiosis
Kaohsiung Medical University

Recruiting

Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy, Vonoprazan-amoxicillin Dual Therapy and Proton Pump Inhibitor-based Standard Triple Therapy for Hp Eradication

Helicobacter Pylori Eradication

Taiwan
Bayer

Not yet recruiting

A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation
International Research Training Group 2804
German Research Foundation; Uppsala University; University Hospital Tuebingen

Not yet recruiting

Breast Cancer & Antiestrogenic Therapy & Brain

Menopause | Breast Cancer Female | Healthy Female | Anti-estrogenic Therapy

Germany

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