Search clinical trials for: Autophagy inhibition

Total 1340 results

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Phase Ib/II Study Confirmed Inhibition of Autophagy Synergizes Anti-tumor Effect of High Dose CDK4/6i

Inhibition of Autophagy Synergizes Anti-tumor Effect

China
Hospices Civils de Lyon

Unknown

MEK and Autophagy Inhibition in Metastatic/Locally Advanced, Unresectable Neuroblastoma RAS (NRAS) Melanoma (CHLOROTRAMMEL)

Metastatic NRAS Melanoma

France
Abramson Cancer Center of the University of Pennsylvania
University of Pittsburgh; Rutgers Cancer Institute of New Jersey

Completed

Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell Carcinoma

Metastatic Clear Cell Renal Cell Carcinoma

United States
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Completed

Hydroxychloroquine and Temsirolimus in Treating Patients With Metastatic Solid Tumors That Have Not Responded to Treatment

Unspecified Adult Solid Tumor, Protocol Specific

United States
Shiraz University of Medical Sciences

Completed

"Pharmacoepidemiological Evaluation of Autophagy Inhibition in Treatment of HCV Patients Resistant to Standard Therapy. Pilot Study"

Hepatitis C Virus

Iran, Islamic Republic of
Radboud University Medical Center

Unknown

Autophagy Inhibition Using Hydrochloroquine in Breast Cancer Patients

Breast Cancer

Netherlands
Zhujiang Hospital
Guangzhou First People's Hospital; Guangdong Provincial People's Hospital; Shenzhen... and other collaborators

Not yet recruiting

Interleukin-6 Receptor Inhibition for Symptomatic Intracranial Atherosclerosis (IRIS-sICAS)

Ischemia | Stroke | Brain Diseases | Ischemic Stroke | Cerebral Infarction | Atherosclerosis of Artery | Atheroscleroses, Intracranial
Escola Superior de Tecnologia da Saúde do Porto

Not yet recruiting

Effectiveness of the Suboccipital Inhibition Technique in Forward Head Posture.

Individuals With Forward Head Posture

Portugal
Riphah International University

Recruiting

Comparison of INIT and Dry Needling on Trigger Points in Knee OA

Knee Osteoarthritis

Pakistan
University Ghent
Research Foundation Flanders

Recruiting

Exploring Prolonged AMR in ACL Reconstructed Patients

Anterior Cruciate Ligament Injuries | Anterior Cruciate Ligament Rupture | Anterior Cruciate Ligament Tear | Anterior Cruciate Ligament Reconstruction | ACL | ACL Injury | ACL Tear | Arthrogenic Muscle Inhibition | Arthrogenic Muscle Responses

Belgium
Vertex Pharmaceuticals Incorporated

Not yet recruiting

A Microneurography Study of NaV1.8 Inhibition in Healthy Adults

Pain
University of Reading
INNOPURE

Recruiting

The Effects of Vitamin B6 Supplementation on Pain Thresholds and Tolerance

Pain

United Kingdom
Sohag University

Recruiting

Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo

Vitiligo

Egypt
Riphah International University

Recruiting

Effect of Superficial Back Line Relaxation Technique on Hamstring Flexibility in Non Specific Low Back Pain Patients

Low Back Pain, Mechanical | Hamstring Flexibility

Pakistan
Riphah International University

Recruiting

Effects of Sub Occipital Muscle Inhibition Technique in Mechanical Low Back Pain

Mechanical Low Back Pain

Pakistan
Chulalongkorn University

Not yet recruiting

"Quick-starting" of a Quadriphasic Contraceptive Pills, 1 - 3 mg Estradiol Valerate/ 2 - 3 mg Dienogest VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition

Ultrasound Finding: Ovulation Inhibition, Ovarian Activities | Cervical Mucus | Serum Hormonal Profile
Chulalongkorn University

Not yet recruiting

"Quick-starting" of a New Combined Hormonal Contraceptive Pills, 15 mg Estetrol/3 mg Drospirenone VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition

Ultrasound Finding: Ovulation Inhibition, Ovarian Activities | Cervical Mucus | Serum Hormonal Profile
Fundació Sant Joan de Déu
Instituto de Salud Carlos III

Recruiting

Precursors of Binge Eating Disorder in a Clinical Sample of Adolescents With Obesity (PREC-BED)

Obesity | Binge-Eating Disorder | Emotion Regulation | Eating Disorders | Food Addiction | Other Specified Feeding or Eating Disorder | Eating Disorder Nos | BED

Spain
Affiliated Hospital of Nantong University

Not yet recruiting

Pretreatment With HCQ Before Radiotherapy and Chemotherapy in Advanced NPC Patients

Nasopharyngeal Carcinoma

China
University of Minnesota

Not yet recruiting

How Does Cerebellar tDCS Alter Intracortical Inhibition Over Time?

Stroke
Amsterdam UMC, location VUmc
Maastricht University Medical Center; Erasmus Medical Center; St. Antonius Hospital

Not yet recruiting

Neoadjuvant Triple Treatment for Borderline Resectable Pancreatic Cancer (PREOPANC-5) (PREOPANC-5)

Borderline Resectable Pancreatic Cancer
Jord Vink

Not yet recruiting

Interaction Between the Brain Hemispheres - Key to Motor Recovery After Stroke (InterAct)

Stroke

Netherlands
Haaglanden Medical Centre
Takeda; Leiden University Medical Center

Not yet recruiting

Complement Inhibition: Attacking the Overshooting Inflammation @Fter Subarachnoid Hemorrhage (CIAO@SAH) (CIAO@SAH)

Subarachnoid Hemorrhage, Aneurysmal
Ann & Robert H Lurie Children's Hospital of Chicago

Not yet recruiting

Mechanisms of SGLT2 Inhibition in Pediatric Steatotic Liver Disease (SHIELD)

Non-Alcoholic Fatty Liver Disease
GRI Bio Operations, Inc.

Recruiting

Biomarker Modulation and the Inhibition of NKT1 Cells by Oral GRI-0621 in Patients With IPF

Idiopathic Pulmonary Fibrosis

United States
Children's Hospital Medical Center, Cincinnati

Not yet recruiting

ADHD PreSMA Response Inhibition Therapy

Attention Deficit Hyperactivity Disorder
University College, London
Novartis; Cancer Research UK; Janssen Pharmaceutica NV

Not yet recruiting

A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer (STAMPEDE2)

Prostate Cancer Metastatic
University of Washington
Washington State University

Not yet recruiting

Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17 (OralT12)

Hypogonadism, Male
Lebanese University
Haykel Hospital

Recruiting

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA (PTST_PALBEVA)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Chemotherapy | Solid Tumor | Immunotherapy | Targeted Therapy | Precision Therapy

Lebanon
University of Michigan
University of Colorado, Denver; Renal Pre-Competitive Consortium (RPC3)

Recruiting

Renal Mechanism of SGLT2 Inhibition

Diabetic Kidney Disease | Type 2 Diabetes

United States
UMC Utrecht
Alfasigma S.p.A.; ReumaNederland; Autoimmune Research and Collaboration Hub

Not yet recruiting

Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases (DRIMID)

IgG4-related Disease | Idiopathic Inflammatory Myopathies | Behcet's Disease

Netherlands
M.D. Anderson Cancer Center
AbbVie; Syndax Pharmaceuticals; Break Through Cancer

Not yet recruiting

A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib

Acute Myeloid Leukemia

United States
Prof Curdin Conrad
Centre Hospitalier Universitaire Vaudois

Not yet recruiting

TYK2 Inhibition in Paradoxical Psoriasis (TYPP)

Psoriasis

Switzerland
The Netherlands Cancer Institute
Agenus Inc.

Recruiting

Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations (NEOASIS)

Resectable MMR-deficient Solid Tumors | Resectable MMR-proficient Solid Tumors

Netherlands
Noha Elserty

Not yet recruiting

Impact of Visceral Manipulation Versus Integrated Neuromuscular Inhibition Technique in Shoulder Impingement Syndrome

Shoulder Impingement
Hospices Civils de Lyon
Centre International de Recherche en Infectiologie (CIRI)

Not yet recruiting

TOward a Better Understanding of the autoPhagy Machinery for the Identification of Potential Novel Biomarkers and Therapeutic Targets in Crohn's Disease - TOPIC Study (TOPIC)

Crohn's Disease

France
Suzhou Municipal Hospital of Anhui Province
Xuanwu Hospital, Beijing

Recruiting

Effect of Interleukin-6 Receptor Inhibition in Patients With Ischemic Stroke Undergoing Endovascular Treatment (IRIS)

Ischemic Stroke | Endovascular Treatment | Interleukin-6

China
University of Reading
INNOPURE

Not yet recruiting

Testing the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism

Autism

United Kingdom
Emory University
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Cortical Electrophysiology of Response Inhibition in Parkinson's Disease

Parkinson Disease

United States
University Hospital, Montpellier

Not yet recruiting

Evaluation of TEG 6S PM® During Cardiopulmonary Bypass to Detect Postoperative Biological Coagulopathy (PREDIPOC)

Cardiac Surgery | Cardiopulmonary Bypass | Coagulopathy

France
University of California, Berkeley
University of Bergen; University College, London

Not yet recruiting

Neurobehavioral Affective Control Training (N-ACT)

Impulsive Behavior | Affective Symptoms | Emotional Distress | Rumination | Psychopathology | Mood Instability | Mood Lability

United States
Southern Medical University, China

Not yet recruiting

The Effectiveness of HP and TMZ Synergism on Adult Recurrence GBM

Glioblastoma Multiforme
Fox Chase Cancer Center

Recruiting

Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition

Primary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Essential Thrombocytosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

United States
University Ghent
Research Foundation Flanders

Recruiting

The Effect of Cognitive Dual-task Rehabilitation on Arthrogenic Muscle Responses After ACL Reconstruction (AMIRA)

Anterior Cruciate Ligament Reconstruction | ACL Injury | Athrogenic Muscle Responses | Arthrogenic Muscle Inhibition

Belgium
Foundation University Islamabad

Recruiting

Autogenic Inhibition Versus Reciprocal Inhibition Muscle Energy Techniques Effect on Swimming Performance on Swimmers With Scapular Dyskinesis

Scapular Dyskinesis

Pakistan
Fudan University
Shanxi Province Cancer Hospital; Inner Mongolia Cancer Hospital Affiliated...

Recruiting

A Retrospective and Prospective Real-world Study of Molecular Typing in the Treatment of Advanced Thyroid Cancer

Advanced Thyroid Cancer Patients Who Received Target Therapy

China
University of Aarhus
Danish Cardiovascular Academy (DCA); Danish Diabetes Academy; Sygesikringen Danmark and other collaborators

Recruiting

Polyamine Treatment in Elderly Patients With Coronary Artery Disease (PolyCAD)

Myocardial Infarction | Cardiovascular Diseases | Quality of Life | Inflammation | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Cognitive Impairment | Metabolic Syndrome | Ischemic Heart Disease | Dietary Habits | Diastolic Dysfunction | Cognition Disorder | Hypertensive Heart Disease

Denmark
Suzhou Alphamab Co., Ltd.

Recruiting

Factor XI inhibiTion for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty

Knee Arthroplasty, Total

China
Hamilton Health Sciences Corporation
Canadian Institutes of Health Research (CIHR); Population Health Research Institute and other collaborators

Not yet recruiting

Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy (TaRGET)

Arrhythmogenic Right Ventricular Cardiomyopathy | Arrhythmogenic Cardiomyopathy

Canada
SOTIO Biotech AG

Recruiting

A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer

Advanced Solid Tumor | Metastatic Solid Tumor

United States, Spain, Czechia, Belgium, France

Search clinical trials for: Autophagy inhibition

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