Search clinical trials for: BRCA1/2 ( ve)

Total 53529 results

AstraZeneca

Completed

To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.

HER2-ve Metastatic Breast Cancer | Germline BRCA1/2 Mutations | Somatic BRCA1/2 Mutations

Italy, Spain, Poland, Taiwan, Canada, France, Germany, Korea, Republic of, Hungary, Japan, Russian Federation, Turkey, United Kingdom, United States, Bulgaria
AstraZeneca
European Network of Gynaecological Oncological Trial Groups (ENGOT)

Completed

A Study to Examine Olaparib Maintenance Retreatment in Patients With Epithelial Ovarian Cancer. (OReO)

Epithelial Ovarian Cancer

Denmark, France, Germany, Italy, Spain, Poland, Belgium, Canada, United Kingdom, Israel, Norway
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

BRCA and NACT in TNBC Patients (Light-Bright)

Triple-Negative Breast Cancer

Italy
University of Pennsylvania
Inovio Pharmaceuticals

Recruiting

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

BRCA1/2 Mutation

United States
Memorial Sloan Kettering Cancer Center
Phenogen Sciences

Recruiting

Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations

Genetic Testing | BRCA1/2

United States
Cancer Trials Ireland

Active, not recruiting

Upfront Systematic Tumour BRCA Testing in Patients With High Grade Serous or Endometrioid Ovarian, Fallopian Tube or Primary Peritoneal Cancer (HGSEC): The t-BRCA Study

Fallopian Tube Cancer | Primary Peritoneal Carcinoma | Serous Ovarian Tumor | Endometrioid Carcinoma Ovary

Ireland
Centre Georges Francois Leclerc

Not yet recruiting

Use of an Ultra-rapid BRCA1/2 Status Screening Test in Theranostic Indication: Performance and Interest for Patients and Practitioners (TURBO)

Breast Cancer
Vrije Universiteit Brussel

Completed

Immersive Virtual Reality During Robot-assisted Walking.

Healthy

Belgium
Alexandru Eniu
Iuliu Hatieganu University of Medicine and Pharmacy

Completed

BRCA1 and BRCA2 Mutation in Romanian Population: a Study of Genotype - Phenotype Correlation at Diagnosis With Prospective Disease Outcome and Survival

To Determine the Prevalence, Penetrance of BRCA1 and BRCA2 Mutations in Romanian Womens With Breast or Ovarian Cancer

Romania
Abramson Cancer Center at Penn Medicine

Recruiting

BRCA1/2 Flu Vaccine

BRCA1 Mutation | BRCA2 Mutation

United States
Data Collection Analysis Business Management
PAS Research Services

Unknown

Increase Surveillance for Breast and Ovarian Cancers, Also to Determine Targeted Risk-reducing and Preventative Strategies

Hereditary Cancer

United States
Kaiser Permanente

Not yet recruiting

Assessing the Validity of the PAP Problems Triage Tool in Patients With PAP Treatment for Obstructive Sleep Apnea (TriagingTool)

Obstructive Sleep Apnea (OSA)
Institut Paoli-Calmettes

Unknown

Triple Negative Breast Cancer: Study of Molecular and Genetic Factors

Breast Cancer

France
University Hospital, Geneva

Recruiting

Impact of Simulation Training for Obstetrics-gynecology Residents.

Simulation Training

Switzerland
DongGuk University

Completed

Comparison of Endotracheal Intracuff Pressure Between Two Cuff Sealing Methods

Endotracheal Tube

Korea, Republic of
University Health Network, Toronto

Terminated

Capturing BRCA1/2 Mutational Status in Women With High Grade Serous Ovarian Cancer and Impact on Clinical Outcome.

Ovarian Cancer

Canada
Abramson Cancer Center of the University of Pennsylvania

Completed

Multiplex Testing for Evaluation of Breast Cancer Risk, Longitudinal Study

BRCA1/2 Negative

United States
Heart of England NHS Trust
British Lung Foundation

Completed

Computed Tomography Assessment of Regional Ventilation (CURVE) (CURVE)

Lung Neoplasms | Pulmonary Disease, Chronic Obstructive | Emphysema | Lung Diseases, Interstitial

United Kingdom
Lund University

Completed

Written Genetic Counseling and Mutation Analysis of BRCA1 and BRCA2 to Patients With Breast Cancer (BRCAsearch)

Hereditary Breast Cancer

Sweden
University of Utah
National Cancer Institute (NCI)

Completed

Risk Education and Assessment for Cancer Heredity (REACH)

Breast Cancer | Ovarian Cancer | Genetic Predisposition

United States
Pamela Munster
National Cancer Institute (NCI)

Recruiting

Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors

BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation | BRCA Mutation | Checkpoint Kinase 2 Gene Mutation

United States
Sultan Abdulhamid Han Training and Research Hospital...

Completed

Turkish Adaptation of Romantic Relationship Sabotage Scale Validity and Reliability Study (T-RSS)

Unrecognized Condition

Turkey
Erasmus Medical Center

Recruiting

Bilateral Prophylactic Mastectomy; Should we Preserve the Pectoral Fascia? (PROFAS)

Seroma | BRCA1/2 Mutation | Bilateral Prophylactic Mastectomy | Pectoral Fascia

Netherlands
University of Oxford
AstraZeneca

Completed

Olaparib +/- Cediranib or Chemotherapy in Patients With Platinum-resistant Ovarian Cancer (OCTOVA)

Ovarian Cancer

United Kingdom
Duke University

Completed

Ehealth: Second Life Impacts Diabetes Education & Self-Management (SLIDES)

Type 2 Diabetes

United States
University of Texas Southwestern Medical Center

Completed

The Effects of Viscoelastometry Guided Resuscitation During Burn Excision on Post Resuscitation Infections

Burns

United States
AstraZeneca

Completed

Characterizing the Cross-sectional Approach to Investigate the Prevalence of Tissue BRCA1/2 Mutations in Newly Diagnosed Advanced Ovarian Cancer Patients (CHRISTELLE)

Ovarian Neoplasms

Japan
University of Utah
University of Minnesota

Recruiting

Physiology of Unloading VA ECMO Trial

Cardiogenic Shock

United States
Mayo Clinic

Enrolling by invitation

GENetic Risk Estimation of Breast Cancer Prior to Decisions on Preventive Therapy Uptake, Risk Reducing Surgery or Intensive Imaging Surveillance (GENRE2)

Breast Cancer

United States
Queen Mary University of London
Astellas Pharma Inc

Unknown

Short-term Preoperative Treatment With Enzalutamide, Alone or in Combination With Exemestane in Primary Breast Cancer (ARB)

Primary Breast Cancer ER+ve | Primary Breast Cancer AR+ve TNBN

Germany, United Kingdom, Spain, United States, Ireland
National Human Genome Research Institute (NHGRI)
Johns Hopkins Bloomberg School of Public Health

Completed

Adaptation to Living With a BRCA1/2 Mutation

Cancer Genetics

United States
Bayer

Completed

Qlaira rPMS (Regulatory Post Marketing Surveillance) Study in Korea

Contraception

Korea, Republic of
AstraZeneca
Merck Sharp & Dohme LLC; NRG Oncology; Breast International Group; Myriad Genetic... and other collaborators

Active, not recruiting

Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer (OlympiA)

Breast Cancer

United States, Austria, Italy, Spain, Sweden, United Kingdom, Belgium, Poland, France, Switzerland, Canada, Germany, Korea, Republic of, Netherlands, Japan, China, Taiwan, Australia, Argentina, Israel, Hungary, Portugal, Iceland, Puerto...
The Cleveland Clinic

Active, not recruiting

The Therapeutic Effects of Forced Aerobic Exercise in Multiple Sclerosis

Multiple Sclerosis

United States
DynPort Vaccine Company LLC, A GDIT Company

Withdrawn

Safety, Tolerability and Immunogenicity of the Venezuelan Equine Encephalitis (VEE) Attenuated Live-Virus Vaccine

Venezuelan Equine Encephalitis

United States
University Hospital, Montpellier

Completed

Management of Women With BRCA1/2 Mutation

BRCA1 Mutation | BRCA2 Mutation

France
University Hospital, Grenoble

Completed

Soluble VE-cadherin and VE-cadherin Antibody in Sclerodermic Sclerosis (Sclerocadh1)

Systemic Sclerosis | Primary Raynaud Disease

France
University of Miami

Completed

Manual Ventilation Efficacy With MVG Device

Ventilator Lung

United States
Dentsply Sirona Implants and Consumables

Completed

Retrospective Evaluation of Clinical Performance of the Astra Tech Implant System EV When Used in Everyday Practice

Dental Implants

United States, Belgium, Canada, Finland, Germany, Sweden
Heidelberg University

Completed

Feasability Study of Removing the Ovaries and Fallopian Tubes (TG-Adnex)

Ovarian Diseases

Germany
Sun Yat-sen University

Recruiting

Pamiparib in mCRPC With HRD or BRCA1/2 Mutation

Metastatic Castration-resistant Prostate Cancer

China
French Cardiology Society
Pfizer; Henri Mondor University Hospital

Active, not recruiting

Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement. (AMYLOCARTESIAN)

Aortic Valve Stenosis | Amyloidosis | Aging | Heart Disease

France
Fudan University

Unknown

Mutation of BRCA1/2 and Other Potential Genes in Triple-negative Breast Cancer

Breast Cancer

China
Institut Cancerologie de l'Ouest

Recruiting

Women at Risk of Breast Cancer and OLFM4

Hereditary Breast and Ovarian Cancer Syndrome

France
Dana-Farber Cancer Institute
AstraZeneca

Withdrawn

Olaparib in Unresectable/Metastatic Melanoma With BRCA1/2

Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma | Recurrent Metastatic Melanoma

United States
Danish Study Group

Not yet recruiting

Coronary Artery Bypass Grafts or Percutaneous Coronary Intervention for High Risk Patients

LV Dysfunction | IHD

Denmark
Chinese Anti-Cancer Association

Unknown

The Registration Program of BRCA1/2 Gene (RCA)

Breast Cancer

China
Technical University of Munich
University of Cologne; University of Leipzig; University Hospital Schleswig-Holstein and other collaborators

Recruiting

Efficacy of Lifestyle Intervention in BRCA1/2 Mutation Carriers (LIBRE-2)

Hereditary Breast and Ovarian Cancer

Germany
Arizona State University
National Institute on Drug Abuse (NIDA); Phoenix Indian Center; Ain Dah Yung... and other collaborators

Recruiting

Parenting in 2 Worlds Multisite Trial ((P2W))

Parenting | Substance Use | Mental Health Wellness 1 | Risky Health Behavior

United States
Ruhr University of Bochum
University of British Columbia; Friedrich-Alexander-Universität Erlangen-Nürnberg

Completed

Waitlist Controlled Comparison of Cognitive-behavioral vs. Mindfulness-based Online-treatments for Women With Low Sexual Desire (MiSELF)

Hypoactive Sexual Desire Disorder

Germany

Search clinical trials for: BRCA1/2 ( ve)

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