Search clinical trials for: Basophil Histamine Release

Total 5866 results

Creighton University
Takeda

Completed

Roflumilast In-Vitro Basophil Release

Asthma | Allergy

United States
Valenta Pharm JSC

Recruiting

Pharmacokinetics and Bioequivalence of Doxylamine+Pyridoxine and Diclectin

Nausea

Russian Federation
Valenta Pharm JSC

Completed

Pharmacokinetics and Bioequivalence of Doxylamine + Pyridoxine, Film-coated, Enteric-soluble Tablets, and Diclectin, Delayed Release Tablets, in Healthy Volunteers

Nausea | Pregnancy Related

Russian Federation
Eisai Inc.

Completed

Rabeprazole Extended-Release 50 mg vs. Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

United States
Massachusetts General Hospital
Ortho-McNeil, Inc.

Terminated

Pain Study to See if Ultram ER Will Provide Relief to Subjects Whose Pain is Not Well Controlled by Narcotics

Chronic Pain

United States
GlaxoSmithKline
Zensei Pharmaceutical Co., Ltd.

Completed

Bioequivalence Study Between Levocetirizine Oral Disintegrating Tablet (ODT) and Levocetirizine Immediate Release Tablet (IRT)

Rhinitis

Japan
University Hospital, Bordeaux

Completed

Hemodynamic Instability Prevented With Polaramine® Infusion Before Extracorporeal Circulation (HIPPIE)

Hemodynamic Instability | Vasoplegic Syndrome

France
Janssen-Cilag International NV

Withdrawn

A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant
Bausch Health Americas, Inc.

Completed

Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill

Upper Gastrointestinal Bleeding

United States
Bayer

Completed

A Manufacturing Transfer Study Comparing the Bioequivalence of a Single Oral Dose of Claritin-D 12-Hour Extended Release Tablet From 2 Different Manufacturers Under Fasted Conditions in Healthy Adult Subjects

Clinical Pharmacology

United States
Bayer

Completed

A Manufacturing Transfer Study Comparing the Bioequivalence of a Single Oral Dose of Claritin-D 12-Hour Extended Release Tablet From 2 Different Manufactuers Under Fed Conditions in Healthy Adult Subjects

Clinical Pharmacology

United States
Dartmouth-Hitchcock Medical Center

Completed

A Study of Quetiapine and Mirtazapine for the Treatment of Alcohol Dependency

Alcohol Dependence

United States
Sandoz

Completed

To Demonstrate the Relative Bioavailability of Cetirizine Hydrochloride/Pseudoephedrine Hydrochloride 5 mg/120 mg Extended Release (ER) Tablets Under Fasting Conditions

Allergies
Sandoz

Completed

To Demonstrate the Relative Bioavailability of Cetirizine Hydrochloride/Pseudoephedrine Hydrochloride 5 mg/120 mg Extended Release (ER) Tablets Under Fed Conditions

Allergies
Mallinckrodt

Completed

Fasting Study of Chlorpheniramine Polistirex and Hydrocodone Polistirex Capsules and Tussionex® Pennkinetic® Extended Release Oral Suspension

Healthy
Mallinckrodt

Completed

Fed Study of Chlorpheniramine Polistirex and Hydrocodone Polistirex Capsules and Tussionex® Pennkinetic® Extended Release Oral Suspension

Healthy

United States
Eisai Inc.

Completed

Rabeprazole Extended Release 50 mg Versus Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

United States
Bayer

Completed

Effects of Phenylephrine Extended-Release Tablets on Allergy-Related Nasal Congestion (P08498 AM1)

Seasonal Allergic Rhinitis
Alcon Research

Completed

Study of Olopatadine HCl Ophthalmic Solutions Compared to Vehicle Using the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis in Japanese Subjects

Allergic Conjunctivitis
Boehringer Ingelheim

Completed

Epinastine + Pseudoephedrine SR (Slow Release) Versus Epinastine Alone in Patients With Perennial Allergic Rhinitis

Rhinitis, Allergic, Perennial
Creighton University
Novartis Pharmaceuticals

Completed

The Effect of Xolair (Omalizumab) on Allergy Blood Cells

Asthma

United States
Alcon Research

Completed

Assessment of Alcon's Ocular Image Quantification System

Allergic Conjunctivitis

United States
Purdue Pharma LP

Completed

Pharmacokinetics and Safety of ORF Tablets in Pediatric Patients

Opioid Analgesia

United States, Australia, Finland, New Zealand
Creighton University
Novartis

Unknown

The Effect of Xolair on Inhibiting Leukotriene and Cytokine (IL-4 and IL-13) Release From Blood Basophils

Allergy

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Desloratadine and Pseudoephedrine Extended-release Tablets Under Fed Conditions

Healthy

United States
Creighton University
Merck Sharp & Dohme LLC

Unknown

Effect of Montelukast on Basophils, In-vitro

Allergic Rhinitis | Allergic Asthma

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Desloratadine and Pseudoephedrine Sulfate Extended-release Tablets Under Fasting Conditions

Healthy

Canada
AstraZeneca

Completed

A Comparative Efficacy and Safety Study of Nexium Delayed-Release Capsules (40mg qd and 20mg qd) Versus Ranitidine 150mg Bid for the Healing of NSAID-Associated Gastric Ulcers When Daily NSAID Use is Continued

NSAID Associated Gastric Ulcers
OBEcure Ltd.

Completed

Evaluation of Co-Administration of Betahistine as Adjunctive to Olanzapine in Healthy Subjects

Healthy

Romania
AstraZeneca

Completed

A Comparative Efficacy and Safety Study of Nexium Delayed-Release Capsules (40mg qd and 20mg qd) Versus Ranitidine 150mg Bid for the Healing of NSAID-Associated Gastric Ulcers When Daily NSAID Use is Continued in Subjects in the US Only

NSAID Associated Gastric Ulcers
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Loratadine / Pseudoephedrine Sulfate 10/ 240 mg Extended-Release Tablets Under Fed Conditions

Healthy

Canada
Ranbaxy Laboratories Limited

Completed

Bioequivalnce Study of Loratadine / Pseudoephedrine Sulfate 10/ 240 mg Extended-Release Tablets Under Fasting Conditions

Healthy

Canada
Luye Pharma Group Ltd.

Not yet recruiting

To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release Tablets

Major Depressive Disorder
Bostal Drug Delivery Co., Ltd

Not yet recruiting

A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects

Diabetes Mellitus, Type 2
Ontario Clinical Oncology Group (OCOG)
Pfizer

Not yet recruiting

Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma (EMBRACE)

Refractory Multiple Myeloma

Canada
University of Southern California

Not yet recruiting

Ketamine HCl Prolonged Release Oral Tablets for CRPS

Complex Regional Pain Syndromes

United States
Riphah International University

Recruiting

Combine Effect Of Myofascial Release Technique and Ocular Muscle Exercise Among University Students

Headache

Pakistan
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (DACAT)

Drug Hypersensitivity | Drug-Induced Anaphylaxis | Antibiotic Allergy | Drug Allergy | Beta Lactam Adverse Reaction | Cephalosporin Allergy | Cephalosporin Reaction

United States
AbbVie

Recruiting

A Study to Assess BOTOX Injections for the Change of Masseter Muscle Prominence in Adult Participants

Masseter Muscle Prominence

United States
Beijing Hospital of Traditional Chinese Medicine

Not yet recruiting

A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.

Plaque Psoriasis
Preeyaporn Jirakittidul

Not yet recruiting

The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled Trial

Healthy Women | Gynecologic Neoplasm
Fundación Pública Andaluza para la Investigación...

Recruiting

SURGERY VS BOTULINUM TOXIN ON QUALITY OF LIFE IN STROKE PATIENTS: RANDOMIZED TRIAL

Stroke

Spain
Foundation University Islamabad

Recruiting

Comparison Between Effects of Active Release Technique and Post Isometric Relaxation on Adductor Strain in Mixed Martial Arts Fighters

Adductor Strain

Pakistan
AbbVie

Recruiting

A Study to Assess BOTOX Injections in Adult Participants for the Change of Masseter Muscle Prominence

Masseter Muscle Prominence

United States
Central Hospital, Nancy, France

Not yet recruiting

Strategy to Adapt Botulinum Toxin Doses in Dystonia

Dystonia
HealthPartners Institute

Not yet recruiting

Continuous Wearable Monitor for the Detection and Release of Freezing of Gait.

Parkinson Disease

United States
Global Aesthetics LLC

Recruiting

Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation

Wrinkle

United States
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathy

Painful Diabetic Neuropathy
MedSIR
Stemline Therapeutics, Inc.

Not yet recruiting

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. (ADELA)

Advanced Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | ESR1 Gene Mutation
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer

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