Search clinical trials for: Beta-thalassemia major

Total 4341 results

Pharmacosmos A/S
ICON plc

Recruiting

A Trial Testing SP-420 in Subjects With Transfusion-dependent β-thalassemia

Beta Thalassemia Major Anemia

Denmark
Central Hospital, Nancy, France

Not yet recruiting

Thrombin Generation in Beta-thalassemia Major (TG-THAL)

Beta Thalassemia Major Anemia
Ain Shams University

Recruiting

PK of SOF/LED in HCV - Infected Adolescents With Haematological Disorders

HCV Infection | Beta Thalassemia Major

Egypt
Paul Szabolcs

Recruiting

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Sickle Cell Anemia | Diamond-blackfan Anemia | Beta-thalassemia Major

United States
Chiesi Canada Corp

Completed

Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children (START)

Iron Overload | Beta Thalassemia Major Anemia

Egypt, Indonesia
Sangamo Therapeutics
Sanofi

Completed

A Study to Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT)

Transfusion Dependent Beta-thalassemia

United States
Celgene

Terminated

Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.

Beta Thalassemia Intermedia | Beta Thalassemia Major

France, United Kingdom, Italy, Greece
M.D. Anderson Cancer Center

Withdrawn

Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

Sickle Cell Disease | Sickle Beta Thalassemia | Beta Thalassemia Major | Sickle Cell-SS Disease | Sickle Beta 0 Thalassemia | Sickle Beta Plus Thalassemia

United States
EmeraMed

Completed

Phase 2a Pilot Study of NBMI Treatment in Patients With Beta Thalassemia Major, Requiring Iron Chelation (EMERA007)

Beta Thalassemia Major

Albania
Northwell Health

Completed

HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity

Sickle Cell Disease | Beta Thalassemia-Major

United States
Assiut University

Unknown

Complications in Children With B- Thalassemia Major

Beta-thalassemia
Indonesia University

Completed

The Effect of Alpha-tocopherol in Hemolysis and Oxidative Stress Marker on the Red Cell Membrane Beta-thalassemia Major

Hemolysis | Oxidative Stress | Beta Thalassemia Major Anemia

Indonesia
Aga Khan University

Completed

Anthropometric Measurements in Children Having Transfusion-dependent Beta Thalassemia

Beta Thalassemia Major
Tanta University

Completed

Effect of Spirulina on Serum Hyaluronic Acid in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Ain Shams University

Completed

Zinc Supplementation in Patients With β-Thalassemia Major Complicated With Diabetes Mellitus

Beta-thalassemia Major Complicated With Diabetes

Egypt
Tanta University

Completed

Effect of Spirulina on Liver Iron Concentration in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Tanta University

Completed

Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
First Affiliated Hospital of Guangxi Medical University

Unknown

Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism

Beta Thalassemia Major

China
Cairo University

Unknown

The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia Major

Beta Thalassemia Major Anemia

Egypt
Tanta University

Completed

Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta Thalassemia

Beta Thalassemia Major

Egypt
Tanta University

Completed

the Potential Immunomodulatory Effects of Spirulina on Thalassemic Children

Beta Thalassemia Major

Egypt
Nanfang Hospital of Southern Medical University
Guangdong Yike Gene Science and Technology CO.,Ltd

Unknown

Gene Therapy for Beta-Thalassemia Major Using Autologous Hematopoietic Stem Cell Genetically Modified

Beta Thalassemia Major

China
Novartis

Completed

A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional Hemosiderosis

Beta-Thalassemia | Hemosiderosis

Egypt, Lebanon, Oman, Saudi Arabia, Syrian Arab Republic
Memorial Sloan Kettering Cancer Center

Completed

Assess the Feasibility and Safety of Granulocyte Colony Stimulating Factor (GCSF) Mobilization of CD34+ Hematopoietic Progenitor Cells in Patients With Betathalassemia Major

Beta Thalassemia Major | Congenital Anemias

United States
University of British Columbia

Unknown

Utility of Fibroscan in Estimating Hepatic Iron Concentration

Hereditary Anemias

Canada
Ain Shams University

Unknown

An Algorithm to Start Iron Chelation in Minimally Transfused Young Beta-thalassemia Major Patients

Beta Thalassemia Major

Egypt
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Genzyme, a Sanofi Company; George Papanicolaou Hospital

Completed

Evaluating the Safety and Effectiveness of Mozobil Mobilization in Adults With Beta-Thalassemia Major

Beta-Thalassemia

Greece
Assistance Publique Hopitaux De Marseille

Completed

Beta-thalassemia and Microparticles

Thalassemia Major (TM) | Thalassemia Intermedia (TI) | Microparticles (MP)Originating From Platelets, Endothelial Cells and Monocytes

France
China Medical University Hospital

Completed

Clinical Trial of Deferasirox Combination Treatment With Deferiprone In Thalassaemia Patients

Beta-thalassemia Major
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); George Papanicolaou Hospital

Completed

Evaluating the Safety of G-CSF Mobilization in Individuals With Beta Thalassemia Major

Beta-Thalassemia

Greece
Ain Shams University

Unknown

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Sickle Cell Disease | Beta-thalassemia Major | Iron Hemosiderosis

Egypt
Novartis Pharmaceuticals

Completed

Extension Study of the Efficacy and Safety of Deferasirox Treatment in Beta-thalassemia Patients With Transfusional Hemosiderosis (Study Amended to 2-year Duration) (ESCALATOR)

Iron Overload | Hemosiderosis | Beta-thalassemia Major | Rare Anemia

Egypt, Oman, Saudi Arabia, Syrian Arab Republic, Lebanon
Isfahan University of Medical Sciences
Madaus Inc

Unknown

Therapeutic Effects of Silymarin in Patients With B-thalassemia Major

Iron Overload | Beta-thalassemia Major

Iran, Islamic Republic of
Royal Brompton & Harefield NHS Foundation Trust
CORDA, The Heart Charity; Apotex Inc.; The Cooley's Anemia Foundation,; The UK...

Unknown

Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major

Beta-Thalassemia

Italy
Luye Pharma Group Ltd.

Not yet recruiting

To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release Tablets

Major Depressive Disorder
Duygu Akyol

Not yet recruiting

Postoperative Analgesia in Major Gynecological Cancer Surgeries

Analgesia | Analgesia, Epidural | ERAS
China National Center for Cardiovascular Diseases

Not yet recruiting

Effect of Xuesaitong Soft Capsules on Major Risk Factors in Patients With Coronary Heart Disease

Coronary Heart Disease

China
Biohaven Therapeutics Ltd.

Not yet recruiting

Long-term Safety Study of BHV-7000 in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body (FERVENT-1)

Non-transfusion Dependent Beta-thalassemia (NTDT)
British University In Egypt

Not yet recruiting

Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers

Treatment Compliance | Aphthous Stomatitis (Major) (Minor)

Egypt
Biohaven Therapeutics Ltd.

Not yet recruiting

Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

Major Depressive Disorder
Shanghai Mental Health Center
University of Electronic Science and Technology of China; Shanghai Jiao Tong... and other collaborators

Recruiting

Non-invasive BCI and Application Verification for Depressed People

Depression | Bipolar Depression | Major Depressive Disorder

China
Cell Energy Life Sciences Group Co. LTD
Beijing 302 Hospital

Recruiting

Stem Cell Treatment for Lung Injury Caused by Major Infectious Diseases

Lung Injury

China
University of Gaziantep

Recruiting

The Effect of Mindfulness-Based Psychoeducation (Mindfulness)

Depressive Disorder, Major

Turkey
University Hospital Tuebingen
German Center for Mental Health

Not yet recruiting

Pharmacologic Treatment Augmentation in Chronic Depression (Ket+CBASP)

Major Depressive Disorder

Germany
Shanghai Mental Health Center

Not yet recruiting

Effectiveness of MST Versus ECT for Major Depressive Episode

Major Depressive Disorder (MDD)

China
Samsung Medical Center

Recruiting

Maternal and Offspring Outcomes in Pregnant Women With Pre-existing ASCVD (CVD_OBS)

Cardiovascular Diseases | Atherosclerosis | Pregnancy Complications | Adverse Cardiac Event | Adverse Birth Outcomes

Korea, Republic of
Università Vita-Salute San Raffaele

Not yet recruiting

Prehabilitation in Oncological Patients Undergoing Major Gastrointestinal Surgery (PROGRESS) (PROGRESS)

Major Surgery | Oncological Patients

Italy
Unity Health Toronto
University of Toronto

Not yet recruiting

Physical Activity Program for TRD

Major Depressive Disorder | Treatment-resistant Depression

Canada
The Hong Kong Polytechnic University

Recruiting

Vulnerability Markers for Depression

Healthy | Major Depressive Disorder | Major Depressive Disorder Remission

Hong Kong

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