Search clinical trials for: Bile acid sequestrant

Total 29873 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Contrast-enhanced MRI in Detecting Benign and Malignant Liver Lesions

Hepatocellular Carcinoma | Liver and Intrahepatic Bile Duct Disorder | Metastatic Malignant Neoplasm in the Liver | Primary Malignant Liver Neoplasm

United States
Ain Shams University

Completed

Efficacy and Safety of Cholestyramine in the Management of Hyperphosphatemia in Adult Hemodialysis Patients

Chronic Kidney Diseases | Hemodialysis Complication | Hyperphosphatemia

Egypt
Lars Kristian Munck
Pierre and Marie Curie University

Completed

Effect of the Sequestrant Colesevelam in Bile Acid Diarrhoea (SINBAD)

Bile Acid Malabsorption | Chronic Diarrhea

Denmark
Steno Diabetes Center Copenhagen
Sanofi

Completed

GLP-1-mediated Gluco-metabolic Effects of Bile Acid Sequestration (SeveX)

Type 2 Diabetes Mellitus

Denmark
Daiichi Sankyo, Inc.

Completed

Colesevelam for Children With Type 2 Diabetes (WELKid DM)

Type 2 Diabetes Mellitus

United States
Hvidovre University Hospital
University of Copenhagen

Completed

Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Severe Obesity

Denmark
University Hospital, Gentofte, Copenhagen
Sanofi

Completed

Effect of Bile Acid Secretion and Sequestration on GLP-1 Secretion

Diabetes Mellitus, Type 2

Denmark
University Hospital, Gentofte, Copenhagen
Sanofi

Completed

Effect of Bile Acid Sequestration on Postprandial GLP-1 Secretion, Glucose Homeostasis and Gut Microbiota

Type 2 Diabetes

Denmark
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety Study of MCI-196 Versus Simvastatin for Dyslipidaemia in Chronic Kidney Disease (CKD) Subjects on Dialysis

Chronic Kidney Disease

Belarus, Bulgaria, Romania, Malaysia, Singapore, Thailand, Italy, Lithuania, Latvia, Croatia, Denmark, Israel, Indonesia
Genzyme, a Sanofi Company
Manipal Acunova Ltd.

Completed

A Multicenter, Active and Placebo-controlled Study of Enteric Coated Sevelamer in Patients With Mild to Moderate Hypercholesteremia (Sevelamer ECS)

Hypercholesterolemia

India
Louisville Metabolic and Atherosclerosis Research...
Daiichi Sankyo, Inc.; Provident Clinical Research

Completed

A Single Research Site Bile Acid Sequestrant Acceptability (BASA) Scale Pilot Validation Study

Healthy

United States
Louisville Metabolic and Atherosclerosis Research...
Daiichi Sankyo, Inc.; Provident Clinical Research

Completed

Comparison of Colesevelam Hydrogen Chloride (HCl) Powder For Oral Suspension Versus Generic Cholestyramine Through Use of the Bile Acid Sequestrant Acceptability (BASA) Scale

Healthy

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (BEZURSO 2)

BPC | Non Optimal Response to UDCA

France
Mayo Clinic

Not yet recruiting

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

WHO Grade 3 Glioma | WHO Grade 2 Glioma | WHO Grade 4 Glioma

United States
Ain Shams University
Misr International University; University of Nizwa

Recruiting

Chitosan-Hyaluronate Gel Mixture Vs Hyaluronic for Internal Derangement (TMJ)

TMJ Disc Disorder

Egypt
Semmelweis University

Recruiting

The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate (NEOKOFF22)

Premature Birth | Respiratory Failure | Apnea of Prematurity

Hungary
Institut Investigacio Sanitaria Pere Virgili

Not yet recruiting

Circulating Microvesicles Regulating Metabolic Homeostasis in Obesity After Caloric Restriction Programs (TREV)

Obesity
Nimble Science Ltd.

Not yet recruiting

The Digestion of Protein Powders in Healthy Participants Using SIMBA and LIMBA Capsule

Nutrition | Microtia | Amino Acid Change | Food Science | Digestion Rate

Canada
University of California, Davis
National Institutes of Health (NIH)

Recruiting

Molecularly Targeted Theranostic Approach for the Detection and Treatment of Metastatic Carcinomas

Metastatic Cancer

United States
TC Erciyes University

Recruiting

Effect of Different Irrigation Solutions on Postoperative Pain and Lesion Healing

Endodontic Disease

Turkey
Ipsen

Not yet recruiting

A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid. (ELSPIRE)

Primary Biliary Cholangitis
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
ECOG-ACRIN Cancer Research Group

Not yet recruiting

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

Glioblastoma, IDH-Wildtype
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
Jonsson Comprehensive Cancer Center
Novartis Pharmaceuticals

Not yet recruiting

Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
Sanjiv Harpavat
Baylor College of Medicine

Not yet recruiting

Tolerability of Enteral NAC in Infants

Biliary Atresia
University of Manchester

Not yet recruiting

The 8x5 Diet for Bile Acid Diarrhoea: A Feasibility Randomised Controlled Trial

Bile Acid Diarrhea

United Kingdom
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Primary Biliary Cholangitis

United States, Japan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Role of Bile Acids and Microbiota in Clostridioides Difficile Infection in Ulcerative Colitis (ABRICO)

Ulcerative Colitis

France
University of California, Davis
United States Department of Defense

Recruiting

Molecularly Targeted Radionuclide Therapy Via the Integrin Alphavbeta6

Metastatic Nonsmall Cell Lung Cancer

United States
Çanakkale Onsekiz Mart University

Not yet recruiting

Evaluation of the Effectiveness of Home-Use Desensitizing Agents on Dentin Hypersensitivity

Dentin Sensitivity
Jonsson Comprehensive Cancer Center

Not yet recruiting

Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)

Prostate Carcinoma | Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) v8

United States
University of North Carolina, Chapel Hill

Recruiting

Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction

Anosmia | Olfaction Disorders | Post-Acute COVID-19 Syndrome | Long Haul COVID-19

United States
Maria Sklodowska-Curie National Research Institute...

Not yet recruiting

The Evaluation of the Effectiveness, Safety and Tolerability of Treatment, Using a PSMA-Lu177, in Patients With ACC- an Open, Non-commercial Clinical Trial (LuRM_ACC/2023)

Adenoid Cystic Carcinoma

Poland
Mayo Clinic

Recruiting

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
St. Boniface Hospital

Not yet recruiting

Impact of Therapy Using Colesevelam Treatment Reducing Bile Acids in Patients With Fontan Circulation. (MYSTIC)

Fontan Circulation
POLYSAN Scientific & Technological Pharmaceutical...

Recruiting

Comparative Study of REMAXA®, Enteric-coated Tablets and REMAXOL®, Solution for Infusions, in Intrahepatic Cholestasis

Cholestasis, Intrahepatic

Russian Federation
Batterjee Medical College

Not yet recruiting

Cost-effective Treatment of Unexplained Infertility

Unexplained Infertility

Saudi Arabia
Hospices Civils de Lyon

Not yet recruiting

Role of BMP Pathway in MDS Progression (BMP-MDS)

Myelodysplastic Syndromes | Acute Myelogenous Leukemia

France
Han Ying

Recruiting

Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
University of Washington
Novartis; Institute for Prostate Cancer Research (IPCR)

Not yet recruiting

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Region Stockholm
Amgen

Not yet recruiting

Studies to Gain Insight How the Drugs PCSK9-inhibitors and Statins Affect Cholesterol and Bile Acid Metabolism

Acute Metabolic Effects of Evolocumab and Atorvastatin
Intercept Pharmaceuticals

Not yet recruiting

Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy

Biliary Atresia
Air Force Military Medical University, China

Recruiting

A Single-center, Prospective Cohort Study on the Differentiation of Benign and Malignant Bile Duct Stenosis Based on Bile and Peripheral Blood cfDNA Methylation Profiles

Bile Duct Diseases | Bile Duct Neoplasms | Jaundice, Obstructive

China
NYU Langone Health
National Institutes of Health (NIH)

Recruiting

Advanced Diffusion Imaging in Renal Cancer Patients

Renal Cancer

United States
National University of Malaysia

Recruiting

Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.

Pancreatic Cancer | Cholangitis | Choledocholithiasis | Choledochal Cyst

Malaysia
Jonsson Comprehensive Cancer Center
Janssen Scientific Affairs, LLC

Recruiting

Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial (HEATWAVE)

Prostate Adenocarcinoma | Stage II Prostate Cancer AJCC v8 | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8

United States
CymaBay Therapeutics, Inc.

Recruiting

IDEAL: Intended to Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects With Primary Biliary Cholangitis (PBC) and an Incomplete Response or Intolerance to Ursodeoxycholic Acid (UDCA) (IDEAL)

Primary Biliary Cholangitis

United States
Guerbet

Recruiting

Performance of Elucirem® in DSC-MRI Perfusion of Brain Gliomas (GDX-44-016)

Brain Tumor, Recurrent | Brain Tumor, Primary

Italy, Hungary, Poland
General Committee of Teaching Hospitals and Institutes...

Not yet recruiting

Comparison of the Absorption of Calcium Citrate and Calcium Carbonate in Patients With an RYGB, LSG, and OAGB (CALCOR-RSO)

Calcium Citrate Absorption | Calcium Carbonate Absorption

Egypt

Search clinical trials for: Bile acid sequestrant

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