Search clinical trials for: Bioequivalence metformin hydrochloride

Total 11454 results

Geropharm

Completed

Bioequivalence Study of Metformin 1000 mg Tablets Immediate Release (IR) Versus Glucophage® 1000 mg Tablets IR In Healthy Subjects

Bioequivalence

Russian Federation
Geropharm

Completed

Bioequivalence Study of Metformin 750 mg Tablets XR Versus Glucophage® Long 750 mg Tablets XR In Normal Healthy Subjects Under Fasting and Fed Conditions

Bioequivalence

Russian Federation
GlaxoSmithKline

Completed

Bioavailability of Two Combination Products of Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) in Asian Males. (ARI115707)

Prostatic Hyperplasia

Australia
GlaxoSmithKline

Completed

A Study Assessing a Range of Formulations of the Fixed Dose Combination Product Containing Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) to Find a Formulation Which is Bioequivalent to Harnal-D Tablets (Tamsulosin Hydrochloride, 0.2mg) in Healthy Male Subjects From North East Asia

Prostatic Hyperplasia

Australia
Anna Maria Storniolo
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride vs. Placebo in Overweight or Obese Patients at Elevated Risk for Breast Cancer

Obesity | Breast Cancer

United States
Jeil Pharmaceutical Co., Ltd.

Completed

Investigate the Effect of Food on the Pharmacokinetics of JLP-1310 in Healthy Male Volunteers

Diabetes | Hyperlipidemia

Korea, Republic of
University of Louisville
James Graham Brown Cancer Center

Terminated

Second Line Erlotinib (Tarceva) Plus Digoxin in Non-Small Cell Lung Cancer

Carcinoma, Non-Small Cell Lung
GlaxoSmithKline

Completed

Efficacy and Safety Study of Rosiglitazone/Metformin Therapy vs Rosiglitazone and Metformin in Type 2 Diabetes Subjects

Diabetes Mellitus, Type 2

United States, Canada, Korea, Republic of, Australia, New Zealand, Mexico, Brazil
S.C.B. Medical College and Hospital

Completed

OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS

PCOS

India
AstraZeneca

Completed

A Study to Assess the Bioequivalence of Dapagliflozin/Metformin XR Fixed-dose Combination Tablets in Healthy Subjects

Bioequivalence | Fixed Dose Combination Tablets | Healthy Male and Female Subjects

United States
AstraZeneca
Biocard

Completed

An Open-label, Randomized, Crossover Study of Comparative Pharmacokinetics and Bioequivalence of Dapagliflozin + Metformin, 10 mg + 1000 mg Versus the Combined Use of Forxiga™, 10 mg and Two Glucophage® Long, ER Tablets, 500 mg Co-administered to Healthy Volunteers Under Standard Fed Conditions

Diabetes Mellitus, Type 2

Russian Federation
Institut für Pharmakologie und Präventive Medizin
Pharma Medica Research, Inc.

Completed

Single-Dose Bioavailability Study of Two Formulations of Ibuprofen and Pseudoephedrine Hydrochloride Tablets

Fever | Pain, Acute | Pain, Back | Pain, Head

Canada
Laboratorios Silanes S.A. de C.V.

Completed

Clinical Trial to Evaluate Safety and pK Profile of Metformin Glycinate in Healthy Volunteers (NTC00940472)

Healthy

Spain
Laboratorios Silanes S.A. de C.V.
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Unknown

Efficacy Study of Metformin Glycinate on Postprandial Lipemia

Type 2 Diabetes

Mexico
Laboratorios Silanes S.A. de C.V.

Completed

Metformin Glycinate on Metabolic Control and Inflammatory Mediators in Type 2 Diabetes (COMET)

Type 2 Diabetes

Mexico
British Columbia Cancer Agency
BC Cancer Foundation; Pancreatic Cancer Canada

Unknown

The Effects of Neoadjuvant Metformin on Tumour Cell Proliferation and Tumour Progression in Pancreatic Ductal Adenocarcinoma (Metformin 001)

Resectable Pancreatic Ductal Adenocarcinoma

Canada
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

Recurrent Prostate Cancer | Stage I Prostate Cancer | Adenocarcinoma of the Prostate | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
AstraZeneca

Completed

Bioequivalence Study of Combination Tablets of Saxagliptin / Dapagliflozin / Metformin XR (Extended-release) and Dapagliflozin / Metformin XR Relative to Individual Components in Healthy Subjects

Type 2 Diabetes Mellitus

United Kingdom
NHS Tayside
University of Southern Denmark; Helmholtz Zentrum München; University of Dundee

Completed

Pharmacokinetics of Metformin Intolerance (POMI)

Diabetes Mellitus, Type 2 | Metformin Adverse Reaction
Galen Limited

Completed

Bioequivalence Study of Nefopam Hydrochloride 30mg Tablets vs Acupan® 30mg Tablets in Healthy Subjects

Healthy

United Kingdom
GlaxoSmithKline

Completed

Evaluation of Food Effect on the Pharmacokinetics of Sustained Release Metformin in Healthy Indian Volunteers

Diabetes Mellitus, Type 2
Beijing Chao Yang Hospital

Completed

Comparison of Exenatide and Metformin Monotherapy in Overweight/Obese Patients With Newly Diagnosed Type 2 Diabetes

Type2 Diabetes
Laboratorios Silanes S.A. de C.V.
INTEC Instituto de Terapéutica Experimental y Clínica, Departamento de Fisiología... and other collaborators

Suspended

Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity (Metfluo)

Overweight and Obesity

Mexico
Columbia University
Astellas Pharma Inc; Susan G. Komen Breast Cancer Foundation

Completed

Study of Erlotinib and Metformin in Triple Negative Breast Cancer

Breast Cancer

United States
AstraZeneca
Parexel

Completed

A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual Component Co-administration.

Type 2 Diabetes Mellitus

United States
GlaxoSmithKline

Completed

SECOTEX® (Tamsulosin Hydrochloride) Bioequivalence Study Brazil - Fast Admin

Prostatic Hyperplasia

Brazil
GlaxoSmithKline

Completed

SECOTEX® (Tamsulosin Hydrochloride) Bioequivalence Study Brazil - Fed Admin

Prostatic Hyperplasia

Brazil
GlaxoSmithKline

Completed

Avandamet Bioequivalence Study Brazil - Fed Administration

Diabetes Mellitus, Type 2

Brazil
National Institute of Nursing Research (NINR)

Completed

Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain

Pain

United States
Ain Shams University

Completed

Adding Metformin to Insulin in Controlling Pregestational and Gestational Diabetes Mellitus

Gestational Diabetes Mellitus in Pregnancy
GlaxoSmithKline

Completed

A Study to Determine the Bioavailability of a Fixed Dose Combination Product of Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) Relative to Co-administration of the Individual Components in Healthy Male Subjects of North East Asian and Non-Asian Ancestry. (ARI114694)

Prostatic Hyperplasia

Australia
Merck Sharp & Dohme LLC

Completed

MK0431A vs. Pioglitazone in Patients With Type 2 Diabetes Mellitus (0431A-066)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

MK0431A Comparative Study in Patients With Type 2 Diabetes (0431A-079)(COMPLETED)

Type 2 Diabetes Mellitus
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Completed

Assess Bioequivalence of Two Formulations of Doxorubicin Hydrochloride Liposome in Female Patients With Ovarian Cancer

Ovarian Cancer

China
Merck Sharp & Dohme LLC

Completed

A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Efficacy and Safety of Sitagliptin and MK0431A in Comparison to a Commonly Used Medication in Patients With Type 2 Diabetes (0431-068)(COMPLETED)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)

Type 2 Diabetes Mellitus
Genzum Life Sciences

Completed

BE Study of Naftifine HCL

Tinea Pedis

United States, Dominican Republic
Merck Sharp & Dohme LLC

Completed

Sitagliptin Comparative Study in Patients With Type 2 Diabetes (0431-049)

Type 2 Diabetes Mellitus
Taro Pharmaceuticals USA

Completed

Evaluate the Safety & Bioequivalence of a Generic Butenafine Cream & Lotrimin Ultra® & Compare Both to a Vehicle Control in Treatment of Interdigital Tinea Pedis

Tinea Pedis
Johns Hopkins University
National Institute of Mental Health (NIMH); University of Maryland; University... and other collaborators

Completed

Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics (IMPACT)

Psychotic Disorders

United States
Boehringer Ingelheim
Eli Lilly and Company

Completed

Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female

Healthy

Germany
Boehringer Ingelheim
Eli Lilly and Company

Completed

Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Subjects

Healthy

Germany
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Boehringer Ingelheim

Completed

Demonstrate Bioequivalence of Two 12.5 mg Empagliflozin/500 mg Metformin Fixed Dose Combination Tablets With Free Combination of Empagliflozin 25 mg and Metformin 1000 mg in Healthy Male and Female Volunteers Under Fed Conditions

Healthy

Russian Federation
Instituto Brasileiro de Osteopatia

Completed

Analysis of the Effects of the Osteopathic Manipulative Treatment in Carriers of Temporomandibular Disorders

Temporomandibular Disorder

Brazil
Takeda

Completed

Special Drug Use Surveillance of Pioglitazone/Metformin Hydrochloride Combination Tablets Survey on Long-term Use for Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

3

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