Search clinical trials for: Brain stem glioma

Total 51845 results

Beijing Tiantan Hospital

Not yet recruiting

Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma (CSAγδTBMG)

Medulloblastoma | GBM | DIPG Brain Tumor

China
Neonc Technologies, Inc.

Not yet recruiting

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

High Grade Glioma | Pineocytoma | Diffuse Midline Glioma, H3 K27M-Mutant | Spinal Cord Tumor | Pediatric Tumor of CNS | Pediatric Tumor of Brain | Pediatric Tumor of Brain Stem | Choroid Plexus Carcinoma, Childhood
Nationwide Children's Hospital
Pfizer

Not yet recruiting

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | WHO Grade III Glioma | WHO Grade IV Glioma | Infant Type Hemispheric Glioma | Diffuse Midline Glioma, H3K27-altered

United States, Australia, Canada, Germany, Netherlands
University of Florida
Oligo Nation, Inc

Not yet recruiting

ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients (ADAGiO)

Recurrent Oligodendroglioma | Progressive Oligodendroglioma

United States
Chulalongkorn University
King Chulalongkorn Memorial Hospital

Recruiting

Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG (CMD03DIPG)

Diffuse Intrinsic Pontine Glioma | DIPG Brain Tumor

Thailand
Rigel Pharmaceuticals
Nationwide Children's Hospital

Not yet recruiting

Study of Olutasidenib and Temozolomide in HGG

Astrocytoma | High Grade Glioma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | Spinal Tumor | Astrocytoma, Grade III | Astrocytoma, Grade IV | IDH1 Mutation | WHO Grade IV Glioma | Thalamus Tumor | IDH1 R132 | IDH1 R132C | IDH1 R132H and other conditions

United States, Australia, United Kingdom, Canada, Germany, Netherlands
xCures
SonALAsense, Inc.

Recruiting

xPedite: A Study to Expedite DIPG and DMG Research

Oncology | DIPG | DMG

United States
Rigshospitalet, Denmark
Karolinska University Hospital; Aarhus University Hospital; Sahlgrenska University... and other collaborators

Not yet recruiting

RE-irradiation of Diffuse MIdline Glioma paTients (REMIT)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Diffuse Glioma | Pontine Tumors | Brain Tumor, Pediatric | Thalamic Tumor
University of Miami

Recruiting

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

Glioblastoma Multiforme | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | DIPG Brain Tumor | H3 K27M | Fibrillary Astrocytomas | Diffuse Intrinsic Brainstem Glioma

United States
Nationwide Children's Hospital
Novartis

Not yet recruiting

Study of Ribociclib and Everolimus in HGG and DIPG

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Nationwide Children's Hospital

Not yet recruiting

Targeted Pediatric High-Grade Glioma Therapy

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Fondazione Policlinico Universitario Agostino Gemelli...
Catholic University of the Sacred Heart; Heinrich-Heine University, Duesseldorf and other collaborators

Recruiting

Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs (2253)

Glioblastoma | Glioma, Malignant

Italy
Seattle Children's Hospital

Recruiting

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Refractory Primary Malignant Central Nervous System Neoplasm | Recurrent CNS Tumor, Adult | Recurrent, CNS Tumor, Childhood

United States
Capital Medical University

Recruiting

Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma

Diffuse Intrinsic Pontine Glioma | Adverse Drug Event | Oncolytic Virus

China
Capital Medical University

Recruiting

Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma

Diffuse Intrinsic Pontine Glioma | Adverse Drug Event | Oncolytic Virus

China
Aminex Therapeutics, Inc.

Recruiting

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Melanoma | Cervical Cancer | Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Solid Tumor | Endometrial Cancer | Advanced Cancer | Diffuse Midline Glioma, H3 K27M-Mutant | Papillary Thyroid Cancer | Solid Carcinoma | Mesotheliomas Pleural | Glioma, Malignant | Ovary Cancer and other conditions

United States, Australia
Gustave Roussy, Cancer Campus, Grand Paris
Innovative Therapies For Children with Cancer Consortium; Chimerix

Recruiting

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0 (BIOMEDE 2)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

France
Jeremy Rudnick, M.D
Kairos Pharma

Not yet recruiting

Activated Autologous T Cells Against Glioma Cancer Stem Cell Antigens for Patients With Recurrent Glioblastoma

Recurrent Glioblastoma

United States
Bambino Gesù Hospital and Research Institute

Recruiting

GD2-CAR T Cells for Pediatric Brain Tumours

High Grade Glioma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Embryonal Tumor | Brain Tumor Adult | Brain Tumor, Pediatric

Italy
Ralph NULL Salloum
Children's Hospital Medical Center, Cincinnati

Recruiting

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

High Grade Glioma | Medulloblastoma | Meningioma | Anaplastic Ependymoma | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Refractory Malignant Glioma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary... and other conditions

United States
SonALAsense, Inc.

Recruiting

A Phase 2 Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients With DIPG

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma

United States
National Cancer Institute (NCI)

Recruiting

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Astrocytoma, Not Otherwise Specified | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Glioblastoma, Not Otherwise Specified

United States, Australia, New Zealand, Canada
Nationwide Children's Hospital

Not yet recruiting

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

High Grade Glioma | Recurrent Medulloblastoma | Diffuse Intrinsic Pontine Glioma

United States
University of California, San Francisco
National Institute of Neurological Disorders and Stroke (NINDS); The Chad-Tough... and other collaborators

Recruiting

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent WHO Grade III Glioma | WHO Grade III Glioma

United States, Netherlands, Israel, Australia, New Zealand, Switzerland
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Roswell Park Cancer Institute; American Lebanese...

Recruiting

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Glioblastoma Multiforme | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | High-grade Astrocytoma NOS

United States, Canada
Ann & Robert H Lurie Children's Hospital of Chicago
Dana-Farber Cancer Institute; University of Calgary; Children's Hospital of Orange...

Recruiting

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States
Children's Oncology Group
National Cancer Institute (NCI); Incuron LLC

Recruiting

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Osteosarcoma | Refractory Osteosarcoma | Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent Diffuse Intrinsic Pontine Glioma | Metastatic Malignant Neoplasm in the Central... and other conditions

United States
University of Florida
Beat Childhood Cancer Research Consortium

Recruiting

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy (PEACH)

Neuroblastoma | Diffuse Intrinsic Pontine Glioma

United States
Bexion Pharmaceuticals, Inc.
CTI Clinical Trial and Consulting Services

Recruiting

A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) (KONQUER)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States
Hospital Infantil Universitario Niño Jesús, Madrid...
Apices Soluciones S.L.

Recruiting

Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy (AloCELYVIR)

Diffuse Intrinsic Pontine Glioma | Medulloblastoma, Childhood, Recurrent

Spain
Yang Zhang
TCRCure Biopharma Ltd.

Recruiting

Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma (ENACTING)

Diffuse Intrinsic Pontine Glioma

China
University of Calgary
The Hospital for Sick Children; CHU de Quebec-Universite Laval; McMaster University and other collaborators

Recruiting

HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

Radiation Toxicity | Radiation Exposure | DIPG | Brain Tumor, Pediatric, Recurrent | Brain Tumor, Pediatric | Brain Tumor, DIPG

Canada
Zhejiang Cancer Hospital

Recruiting

Anlotinib to Malignant Brainstem Glioma

Glioma | Malignant Brain Stem Tumor

China
Nationwide Children's Hospital

Recruiting

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

High Grade Glioma | Diffuse Intrinsic Pontine Glioma

United States, Australia, Canada, Germany
Biotech Pharmaceutical Co., Ltd.

Recruiting

Nimotuzumab in Combined With Chemoradiotherapy to Treat the Newly Diagnosed Diffuse Intrinsic Pontine Glioma in Children

Diffuse Intrinsic Pontine Glioma

China
Tata Memorial Centre

Recruiting

A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma (LoBULarDIPG)

DIPG

India
Actuate Therapeutics Inc.

Recruiting

9-ING-41 in Pediatric Patients With Refractory Malignancies.

Neuroblastoma | Pediatric Cancer | Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor | Refractory Cancer | Refractory Neoplasm | Refractory Tumor | Cancer Pediatric | Neuroblastoma Recurrent | Pediatric Lymphoma | Pediatric Meningioma

United States
Crystal Mackall, MD
National Institutes of Health (NIH); California Institute for Regenerative... and other collaborators

Recruiting

GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)

Glioma of Spinal Cord | Glioma of Brainstem

United States
Seattle Children's Hospital

Recruiting

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Glioma | Ependymoma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Central Nervous System Tumor | Germ Cell Tumor | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Pineoblastoma, Childhood

United States
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine; The Faris Foundation and other collaborators

Recruiting

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

High Grade Glioma | Diffuse Intrinsic Pontine Glioma | Embryonal Tumor | Ependymal Tumor

United States
Theodore S. Johnson
National Cancer Institute (NCI); Emory University; Augusta University

Recruiting

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Glioblastoma | Ependymoma | Medulloblastoma | Diffuse Intrinsic Pontine Glioma

United States
Taproot Health

Recruiting

The Registry of Oncology Outcomes Associated With Testing and Treatment (ROOT)

Melanoma | Sarcoma | Kidney Cancer | Adenocarcinoma | Renal Cell Carcinoma | Cervical Cancer | Acute Myeloid Leukemia | Stomach Cancer | Breast Cancer | Head and Neck Neoplasms | Nasopharyngeal Carcinoma | Glioblastoma | Astrocytoma | Multiple Myeloma | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer and other conditions

United States
Institut Claudius Regaud

Recruiting

Deciphering Mechanisms Underlying Cancer Immunogenicity (DECIDE)

Cervical Cancer | Head and Neck Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Anal Cancer | Cervical Intraepithelial Neoplasia 3 | Glioblastoma Multiforme of Brain Stem

France
National Cancer Institute (NCI)

Recruiting

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

Recurrent Malignant Glioma | Recurrent Medulloblastoma | Refractory Malignant Glioma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Refractory Diffuse Intrinsic Pontine...

United States, Canada
University of Göttingen
Hannover Medical School; Deutsche Kinderkrebsstiftung

Recruiting

International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013) (HIT-HGG-2013)

Diffuse Intrinsic Pontine Glioma | Gliomatosis Cerebri | Glioblastoma WHO Grade IV | Diffuse Midline Glioma Histone 3 K27M WHO Grade IV | Anaplastic Astrocytoma WHO Grade III

Germany
University of Calgary

Recruiting

Re-Irradiation of Progressive or Recurrent DIPG

Recurrent or Progressive Diffuse Intrinsic Pontine Glioma

Canada, Australia, New Zealand
Children's Hospital Medical Center, Cincinnati
The DIPG Collaborative

Recruiting

International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Diffuse Midline Glioma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); NovoCure Ltd.; American Lebanese Syrian Associated...

Recruiting

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

Malignant Glioma | Ependymoma | Diffuse Intrinsic Pontine Glioma

United States
Burzynski Research Institute

Not yet recruiting

Study of Antineoplaston Therapy + Radiation vs. Radiation Only in Diffuse, Intrinsic, Brainstem Glioma (DIPG)

Brain Stem Glioma
Burzynski Research Institute

Not yet recruiting

Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma (DBSG)

Brain Stem Glioma

Search clinical trials for: Brain stem glioma

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