Search clinical trials for: CD4-CD8 Ratio

Total 1602 results

Assiut University

Not yet recruiting

Immune Markers in Pediatric ITP on Second Line Therapy

ITP - Immune Thrombocytopenia
Assistance Publique - Hôpitaux de Paris

Completed

Injection of CD4 and CD8 + T Cells Anti-Cytomegalovirus (CMV) or Anti-adenovirus (CTLantiCMV)

Cytomegalovirus Infections | Adenovirus Infections

France
Nantes University Hospital

Completed

Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis, Asthma and Allergic Rhinitis (Prévall-DP)

Allergic Rhinitis | Atopic Dermatitis | Allergic Asthma

France
Centre Hospitalier Universitaire de Nice

Recruiting

Comparison of Inflammatory Markers and Incidence of Comorbidities in Patients on Antiretroviral Therapy With Second-generation Anti-integrase Drugs on Triple Versus Dual Therapy (COLLATERAL 2)

Hiv

France
Jean-Pierre Routy
St. Joseph's Health Care London

Not yet recruiting

Fecal Microbiota Translantation (FMT) to Reduce Inflammation in PLWH: The Gutsy Pilot Study (Gutsy)

HIV-1-infection
Fundacion para la Investigacion Biomedica del Hospital...

Completed

Effects of Maraviroc vs. Efavirenz on CD4/CD8 Ratio (MeritRate)

HIV/AIDS
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Juno Therapeutics, Inc.

Completed

Immunotherapy With BCMA CAR-T Cells in Treating Patients With BCMA Positive Relapsed or Refractory Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma

United States
Fred Hutchinson Cancer Center
HighPass Bio, Inc.

Suspended

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Acute Myeloid Leukemia | Leukemia | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Chronic Myelomonocytic Leukemia | Recurrent Myelodysplastic Syndrome | Refractory... and other conditions

United States
National Cancer Institute (NCI)

Completed

Vaccine Plus Booster Shots in Men With Prostate Cancer Undergoing Treatment With Radical Prostatectomy

Prostatic Neoplasms | Prostate Cancer | Neoplasms, Prostate

United States
China Medical University Hospital

Completed

Functional Plasticity of Human IL-17-producing CD8+ T Cells

IL-17+ CD8 T Cells in Cancer Patients

Taiwan
National Institute of Allergy and Infectious Diseases...

Terminated

Interleukin-7 (CYT107) Treatment of Idiopathic CD4 Lymphocytopenia: Expansion of CD4 T Cells (ICICLE)

Idiopathic CD4+ T-Lymphocytopenia

United States
AgonOx, Inc.
Providence St Joseph Health; Phio Pharmaceuticals Corp.

Recruiting

Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors (ACT)

Melanoma | Gynecologic Cancer | Colorectal Cancer | Lung Cancer | HNSCC | Urogenital Cancer

United States
Paola Mantegani

Active, not recruiting

Evaluation of a CD4/CD8+ Interferon Gamma Release Assay for Monitoring Anti-Tuberculosis Treatment (IGRA/MAT-1)

Tuberculosis

Italy
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of HIV-Negative Patients With Low CD4+ T Lymphocyte Counts

CD4 Lymphocytopenia | Idiopathic CD4 Positive T Lymphocytopenia

United States
Centre Hospitalier Universitaire de Saint Etienne

Completed

Expression of the Inhibitory Receptors on Lymphocytes T Cells After Lung Cancer Surgery. (POIR)

Lung Cancer | Surgery

France
Glaxo Wellcome

Completed

A Study of Two Anti-HIV Drug Combinations

HIV Infections

United States, Puerto Rico
Medical University of Graz

Completed

HHV-6-specific T-cell Reconstitution Among Children and Adolescents After Allogeneic Stem. (CIRAST HHV-6)

Allogeneic Stem Cell Transplantation
M.D. Anderson Cancer Center
Eligix

Terminated

CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell Transplantation

Multiple Myeloma | Chronic Lymphocytic Leukemia | Chronic Myelogenous Leukemia | Non Hodgkin's Lymphoma | Hodgkin's Disease

United States
Genentech, Inc.

Completed

A Phase I Study of Recombinant CD4(rCD4) in Patients With AIDS and AIDS-Related Complex

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Idiopathic CD4-Positive | T-Lymphocytopenia

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Affini-T Therapeutics, Inc.

Active, not recruiting

Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer

Other Skin

United States
Centre Georges Francois Leclerc

Active, not recruiting

Relevance of T Lymphocytes Tumor Infiltrates CD8 and Foxp3 as Immune Prognostic Biomarker in Breast Cancer Treated by Neo Adjuvant Chemotherapy (PRIMUNEO)

Breast Cancer

France
iCell Gene Therapeutics
Peking University Shenzhen Hospital; iCAR Bio Therapeutics Ltd.

Recruiting

CD4-specific CAR T Cells (CD4 CAR T Cells) for Relapsed/Refractory T Cell Malignancies

Refractory T-Cell Lymphoma | T Cell Lymphoma in Relapse

China
Assiut University

Unknown

Prognostic Value of CD Markers in Immune Thrombocytopenic Purpura

Immune Thrombocytopenia
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Patients With AIDS and AIDS-Related Complex

HIV Infections

United States
Shanghai Public Health Clinical Center

Active, not recruiting

Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor

Renal Cell Carcinoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Non-small Cell Lung Cancer | Pancreas Cancer

China
University of Pennsylvania

Completed

Autologous CD4 T-Cells in HIV (C34-CXCR4)

Hiv

United States
Singh, Ranjan Kumar, M.D.

Completed

Prevalence of HIV +ve Cases With AIDS Defining Opportunistic Infections Among ART Naive Patients Attending ART Centre (ADC)

HIV Infections | Tuberculosis | Cryptococcosis | Leishmaniasis | Candidiasis, Esophageal | Toxoplasmosis

India
Imperial College London

Withdrawn

Autologous Cytomegalovirus (CMV) Specific CD8+ T Cells as Treatment for CMV Reactivation

Allogeneic Stem Cell Transplantation | CMV Reactivation | Autologous CMV Specific CD8+ T Cells

United Kingdom
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 Immunoglobulin G (rCD4-IgG) in Infants and Children With Documented HIV-1 Infection

HIV Infections

United States
National University Hospital, Singapore
Singapore General Hospital

Unknown

T-cell Depleted Donor Lymphocyte Infusion (DLI)for Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia | Myelodysplastic Syndromes

Singapore
Bacchetta, Rosa, MD
Food and Drug Administration (FDA); California Institute for Regenerative Medicine...

Recruiting

CD4^LVFOXP3 in Participants With IPEX

IPEX

United States
Genentech, Inc.

Completed

A Phase I Study of Recombinant Human CD4 Immunoglobulin G (rCD4-lgG) in Patients With HIV-Associated Immune Thrombocytopenic Purpura

HIV Infections | Immune Thrombocytopenic Purpura ( ITP )

United States
Affini-T Therapeutics, Inc.

Recruiting

Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor

Colorectal Cancer | Non-Small Cell Lung Cancer | Solid Tumor | Pancreatic Ductal Adenocarcinoma | KRAS G12V

United States
The Aurum Institute NPC
London School of Hygiene and Tropical Medicine; Johns Hopkins University; United... and other collaborators

Completed

Thol'Impilo: Bringing People Into Care

HIV

South Africa
University of Washington

Completed

Strategies to Increase HIV Testing, Linkages to Care, and Male Circumcision in Africa

HIV

South Africa, Uganda
Instituto Nacional de Ciencias Medicas y Nutricion...

Suspended

Pyridostigmine as Immunomodulator in People Living With HIV

HIV-1-infection | Immune Deficiency | CD4+ T Lymphocytopenia | Immuno-senescence

Mexico
T-knife GmbH

Terminated

A Phase 1/ 2, First-in-Human, Open-Label, Accelerated-Titration, Two-Part Clinical Trial of TK-8001 in Patients With HLA-A*02:01 Genotype and Advanced-Stage/ Metastatic MAGE-A1+ Solid Tumors (IMAG1NE)

Advanced Solid Tumors

Germany, Belgium, Spain, Netherlands, United Kingdom
Rakai Health Sciences Program

Completed

Non-enrolment and Non-adherence to HIV Care in a Community-based Program, Rakai, Uganda

Quality of Life | Adherence | CD4 Deficiency

Uganda
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant Human CD4 Immunoglobulin (rCd4-IgG) Administered by Intravenous Bolus in Patients With AIDS and AIDS Related Complex

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 Immunoglobulin G (rCD4-IgG) in HIV-1 Seropositive Women During the Last Trimester of Pregnancy and Their Newborns

HIV Infections | Pregnancy

United States
VIRxSYS Corporation

Active, not recruiting

A Rollover Study for Subjects Who Completed Participation in the VRX496-USA-05-002 Trial (Rollover)

HIV Infections

United States
University College, London

Unknown

Donor Lymphocyte Infusion After Stem Cell Transplant in Treating Patients With Haematological Cancers (ProT4)

Lymphoma | Leukemia | Myelodysplastic Syndrome | Myeloma | Graft Versus Host Disease

United Kingdom
Wuhan Union Hospital, China

Recruiting

Correlation of Memory CD8+ T Cells With Sepsis Severity and Mortality: a Single-center, Unblinded, Prospective, Non-interventional, Observational Study

Sepsis | Inflammatory Response

China
Ruth M. Rothstein CORE Center

Completed

Lubiprostone as a Modulator of Gut Microbial Translocation in HIV With Incomplete CD4 Recovery on Antiretroviral Therapy (LAMBCHOP)

HIV

United States
Centre Hospitalier Universitaire Dijon

Completed

Study of the T CD8 Immune Response in Horton's Disease (Horton CD8)

Horton's Disease

France
Diwakar Davar
Merck Sharp & Dohme LLC; Gateway for Cancer Research

Not yet recruiting

Pembrolizumab/Lenvatinib With and Without Responder-derived FMT in Relapsed/Refractory Melanoma

PD-1 Refractory Advanced Melanoma

United States
University of Washington

Completed

Overcoming Barriers to HIV/AIDS Care and ART Initiation (LINC)

Engagement in HIV Care

Kenya
National Institute of Allergy and Infectious Diseases...
Biogen

Completed

An Escalating Dose Tolerance Trial of BG8962 (rCD4) in Patients Who Are HIV Antibody Positive

HIV Infections

United States
Guangzhou 8th People's Hospital
Sun Yat-sen University

Completed

Reconstitution of HIV-specific Immunity Against HIV

HIV

China

Search clinical trials for: CD4-CD8 Ratio

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