Search clinical trials for: CXCR4 antagonist

Total 33606 results

Zhongnan Hospital

Recruiting

CXCR4-targeted PET/CT Imaging in Hematological Malignancies

Hematological Malignancy | CXCR4 | PET/CT

China
Zhongnan Hospital

Recruiting

CXCR4 Targeted PET Imaging in APA Preoperative Localization Diagnosis

Aldosterone-Producing Adenoma

China
Xiao Chen

Recruiting

CXCR4 PET/MRI Targeted Imaging for Grading Diagnosis, Molecular Typing, and Prognostic Evaluation of Brain Glioma

Glioma

China
Xiao Chen

Recruiting

CXCR4 Targeted PET Imaging in the Diagnosis and Identification of Primary Aldosteronism

Primary Aldosteronism

China
Matthias Fröhlich

Completed

CXCR4-PET/CT for Diagnosing Giant Cell Arteritis

Vasculitis | Diagnoses Disease

Germany
Peking Union Medical College Hospital

Recruiting

Application of 68Ga-Pentixafor PET/CT for Thymoma

Thymoma

China
Biokine Therapeutics Ltd

Completed

Safety Study of a Chemokine Receptor (CXCR4) Antagonist in Multiple Myeloma Patients

Multiple Myeloma

Israel
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Safety of AMD070 When Administered Alone or Boosted With Low-Dose Ritonavir in HIV Uninfected Men

HIV Infections

United States
Hadassah Medical Organization

Completed

Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months (ASD-CXCR4)

Autism Spectrum Disorder | Complication of Prematurity

Israel
Polyphor Ltd.

Completed

Safety and Efficacy of POL6326 for Mobilization of Hematopoietic Stem Cells in Healthy Volunteers

Healthy

Germany
Samaritan Pharmaceuticals, Inc

Unknown

SP01A: The Study of an Oral Entry Inhibitor in Treatment-Experienced HIV Patients

HIV Infections | Human Immunodeficiency Virus

United States
National Taiwan University Hospital

Unknown

The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma

Laryngeal Cancer | Hypopharyngeal Cancer

Taiwan
X4 Pharmaceuticals

Not yet recruiting

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Neutropenia
Peking Union Medical College Hospital

Recruiting

68Ga-pentixather and 68Ga-pentixafor PET/CT in Multiple Myeloma

Multiple Myeloma

China
X4 Pharmaceuticals

Active, not recruiting

A Study of Mavorixafor in Participants With Congenital Neutropenia and Chronic Idiopathic Neutropenia Disorders

Neutropenia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

An Evaluation of Safety and Efficacy of Escalating Doses of AMD3100 to Mobilize CD34+ Cells in Healthy Volunteers

Healthy Volunteers

United States
University Hospital, Bordeaux

Not yet recruiting

The Role of Cxcr4Hi neutrOPhils in InflueNza (CHOPIN)

Influenza | Acute Respiratory Distress Syndrome

France
Wuerzburg University Hospital

Recruiting

Lymphatic Organs and Myocardium After Myocardial Infarction (LOMI)

Myocardial Infarction | Myocardial Injury | Myocardial Inflammation

Germany
Yusuf Menda
National Cancer Institute (NCI); National Institutes of Health (NIH); Holden...

Active, not recruiting

Gallium 68 Pentixafor in Patients With Neuroendocrine Tumors

Neuroendocrine Tumors

United States
Proximagen, LLC

Terminated

Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)

Solid Tumors (Phase 1) | Relapsed/Recurrent GBM (Phase 2)

United States, Spain
National Heart, Lung, and Blood Institute (NHLBI)

Completed

G-CSF and AMD3100 to Mobilize Stem Cells in Healthy Volunteers

Healthy

United States
Washington University School of Medicine

Completed

Chemosensitization With Plerixafor Plus G-CSF in Acute Myeloid Leukemia

Leukemia, Myeloid, Acute

United States
Washington University School of Medicine

Completed

AMD3100 Plus Mitoxantrone, Etoposide and Cytarabine in Acute Myeloid Leukemia (AMD3100+MEC)

Leukemia, Myeloid, Acute

United States
National Taiwan University Hospital

Unknown

The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma

Laryngeal Cancer | Hypopharyngeal Cancer | Metastasis

Taiwan
National Taiwan University Hospital

Unknown

The Role of SDF-1/CXCR4 in Metastasis of Oral Squamous Cell Carcinoma

Oral Cancer

Taiwan
National Cancer Institute, Naples

Recruiting

Nivolumab in mRCC Patients: Treg Function, T-cell Access and NK Interactions to Predict and Improve Efficacy (REVOLUTION)

Metastatic Renal Cell Carcinoma | RCC

Italy
Bristol-Myers Squibb

Completed

First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers

Follicular Lymphoma | Chronic Lymphocytic Leukemia | Acute Myelogenous Leukemia | Diffuse Large B-Cell Leukemia

United States
Sohag University

Unknown

Expression of CXCR4 in Patients With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Sichuan University

Recruiting

CXCR4 Modified Anti-BCMA CAR T Cells for Multiple Myeloma

Multiple Myeloma

China
University of Pennsylvania

Completed

Autologous CD4 T-Cells in HIV (C34-CXCR4)

Hiv

United States
Sheba Medical Center

Withdrawn

Imatinib and BL-8040 (Novel Anti CXCR4 Antagonist) for Improving Molecular Response in Chronic Myelogenous Leukemia

Chronic Myeloid Leukemia

Israel
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Pembrolizumab and CXCR4 Antagonist BL-8040 in Treating Patients With Metastatic Pancreatic Cancer

Metastatic Pancreatic Adenocarcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Recurrent Pancreatic Adenocarcinoma

United States
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Auto-immunity in Lupus Patients After Influenza Vaccine (GRIPLUP)

Systemic Lupus Erythematosus (SLE)

France
National Institute of Allergy and Infectious Diseases...
Lombardi Comprehensive Cancer Center

Terminated

Imaging CXCR4 Expression in Subjects With Cancer Using 64 Cu-Plerixafor

Cancer

United States
Ablynx

Terminated

First in Man Study of ALX-0651, a Nanobody Inhibiting CXCR4

Healthy Volunteers

Netherlands
Memorial Sloan Kettering Cancer Center
Pentixapharm AG

Recruiting

In-Human CXCR4 Imaging of Blood Cancers Using [68Ga]-Pentixafor-PET

Multiple Myeloma | Non-Hodgkin Lymphoma | Erdheim-Chester Disease | Rosai-Dorfman Disease | Histiocytic Neoplasms

United States
Christian Buske
Amgen; Janssen, LP

Recruiting

Efficacy and Safety of Carfilzomib in Combination With Ibrutinib vs Ibrutinib in Waldenström's Macroglobulinemia (CZAR-1)

Waldenstrom Macroglobulinemia

Austria, Germany, Greece
National Cancer Institute, Naples

Active, not recruiting

"Principle Test" for Isolation and Characterization of Circulating Cancer Cells (CTC)-CXCR4+.

Neoplasm Malignant

Italy
First Affiliated Hospital of Fujian Medical University

Recruiting

Value of Chemokine Receptor CXCR4 Imaging for Diagnosis and Prognostic Evaluation in Lymphoproliferative Diseases

Lymphoma | Leukemia | Multiple Myeloma

China
Dana-Farber Cancer Institute
Bristol-Myers Squibb

Terminated

A Study of Ulocuplumab And Ibrutinib in Symptomatic Patients With Mutated CXCR4 Waldenstrom's Macroglobulinemia

Waldenstrom's Macroglobulinemia

United States
Washington University School of Medicine

Completed

Intravenous AMD3100 for Collection of Autologous Peripheral Blood Stem Cells in Patients With Lymphoma

Lymphoma, Non-Hodgkin | Hodgkin Disease

United States
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Safety and Activity of the Oral HIV Entry Inhibitor AMD11070 in HIV Infected Patients

HIV Infections

United States
Polyphor Ltd.

Completed

CXCR4 Antagonism for Cell Mobilisation and Healing in Acute Myocardial Infarction (CATCH-AMI) (CATCH-AMI)

Large Reperfused ST-Elevation Myocardial Infarction

United Kingdom, Austria, Germany, Hungary, Poland
Nantes University Hospital

Not yet recruiting

Study Assessing RLT Using [177Lu]Lu-PentixaTher for Relapsed/Refractory CXCR4+ Acute Leukemia. (PENTILULA)

Acute Leukemia

France
Peking Union Medical College Hospital

Unknown

Chemokine Receptor CXCR4-targeting Molecular Imaging for Metabolic Characterization of Multiple Myeloma and Lymphoma

Lymphoma | Multiple Myeloma

China
Washington University School of Medicine
Biogen; BioLineRx, Ltd.

Recruiting

Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD)

Sickle Cell Disease

United States
Bristol-Myers Squibb

Completed

Anti-CXCR4 (BMS-936564) Alone and in Combination With Lenalidomide/Dexamethasone or Bortezomib/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
National Taiwan University Hospital

Unknown

Studies on the Significance of CXCR4-CXCL12 on Leukemic Cells Passing Through"Marrow-Blood Barrier"

Acute Lymphocytic Leukemia | Acute Myelocytic Leukemia

Taiwan
Bristol-Myers Squibb

Completed

Study of MDX-1100 (Anti-CXCL10 Human Monoclonal Antibody) in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (RA) (MDX1100-04)

Rheumatoid Arthritis

Romania, Ukraine
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Chemo Sensitization Before Hematopoietic Stem Cell Transplantation in Patients With Acute Leukemia in Complete Remission

Acute Myeloid Leukemia | Acute Lymphoid Leukemia

Mexico

Search clinical trials for: CXCR4 antagonist

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Singapore

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations