Search clinical trials for: CYCLOSPORINE

Total 954 results

Astellas Pharma China, Inc.

Completed

Efficacy and Safety Study of the Switch From Cyclosporin to Tacrolimus in Renal Transplant Recipients

Renal Transplant Recipients

China
Astellas Pharma Korea, Inc.

Completed

A Study to Assess the Efficacy and Safety of Advagraf® Switching From Cyclosporine Between the Group That Was Treated With a 50% Reduced Corticosteroid and the Group With Maintained Corticosteroid for Stable Kidney Transplant Recipients (COSMOS)

Kidney Transplant

Korea, Republic of
Aristotle University Of Thessaloniki

Completed

From Preserved, to Preservative-free Cyclosporine 0.1% Enhanced Triple Glaucoma Therapy

Glaucoma | Ocular Surface Disease

Greece
Instituto de Investigación Sanitaria de la Fundación...

Completed

Clinical Trial to Assess Efficacy of cYclosporine Plus Standard of Care in Hospitalized Patients With COVID19

COVID19 Infection

Spain
Zynerba Pharmaceuticals, Inc.

Completed

Clinical Study Of caNNabidiol in childrEn and adolesCenTs With Fragile X (CONNECT-FX) (CONNECT-FX)

Fragile X Syndrome

United States, New Zealand, Australia
Taejoon Pharmaceutical Co., Ltd.

Completed

Evaluating HA 0.15% Compared With Cyclosporine 0.05%, and Efficacy of Combination Therapy in Dry Eye Disease Patients

Dry Eye | Dry Eye Syndromes

Korea, Republic of
University of Leeds

Completed

Irinotecan With or Without Panitumumab or Cyclosporine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Fluorouracil

Colorectal Cancer

United Kingdom
Samsung Medical Center

Completed

The Effect of Cyclosporin Before Cataract Surgery

Dry Eye Syndromes

Korea, Republic of
Second Affiliated Hospital of Nanchang University

Completed

Cyclosporine 0.05% Eye Drops for Vernal Keratoconjunctivitis Trial

Vernal Keratoconjunctivitis | Cyclosporine 0.05% Eye Drops

China
Enzyvant Therapeutics GmBH

Approved for marketing

Expanded Access Protocol Thymus Transplantation

Immunodeficiency | Poor Thymic Function | Athymia | Immunoreconstitution | Thymus Transplantation | Low T Cell Numbers
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Approved for marketing

Thymus Transplantation Safety-Efficacy

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States
Santen SAS

Completed

Double-Masked Trial of NOVA22007 (1mg/mL Ciclosporin/Cyclosporine) Versus Vehicle in Pediatric Patients With Active Severe Vernal Keratoconjunctivitis

Vernal Keratoconjunctivitis

United States, Croatia, France, Germany, Greece, Hungary, India, Israel, Italy, Portugal, Spain
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Phase I/II Thymus Transplantation With Immunosuppression #950 (#950)

DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome | Complete Atypical DiGeorge Anomaly | Complete Atypical DiGeorge Syndrome

United States
Peking University Third Hospital

Completed

Evaluation of 0.05% CsA and 0.1% FK506 Eye Drops in Ocular GVHD Treatment

Graft Versus Host Disease in Eye

China
Organon and Co
Schering-Plough

Completed

MD Ezetimibe Cyclosporine Interaction (0653-057)

Cholesterol
Janssen Research & Development, LLC

Completed

A Study in Healthy Adult Participants to Assess the Effects of Ciclosporin Administration on Rilematovir

Healthy

Belgium
Beijing Friendship Hospital

Completed

Multitarget Therapy for Idiopathic Membranous Nephropathy (MTIMN)

Efficacy

China
Tampere University Hospital

Completed

Efficacy of Cyclosporine Rescue Therapy in Acute Ulcerative Colitis. (Cyclo)

Ulcerative Colitis Acute
Mesoblast, Inc.

Completed

Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)

Graft Vs Host Disease

United States
Assiut University

Completed

Eltrombopag & Cyclosporine in Children With Sever Aplastic Anemia (Eltroplastic)

Eltrombopag

Egypt
University of Pennsylvania

Completed

Cyclosporine in Patients With Moderate COVID-19

COVID-19

United States
Santen SAS

Completed

Efficacy and Tolerance of Nova22007 Versus Vehicle in Patients With Vernal Keratoconjunctivitis (VKC)

Conjunctivitis, Vernal

France
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Stem Cell Transplantation for Metastatic Solid Tumors

Neoplasm Metastasis

United States
University of Washington
National Cancer Institute (NCI)

Completed

Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms

Previously Treated Myelodysplastic Syndrome | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts-2 | Myeloid Neoplasm | Chronic Myelomonocytic Leukemia-2 | Blasts 10 Percent or More of Bone Marrow Nucleated... and other conditions

United States
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Completed

Cyclosporine A in Combination With Abacavir Sulfate, Lamivudine, and Zidovudine and Lopinavir/Ritonavir in HIV

HIV Infections

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)

Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Natural Killer Cell Lymphoblastic Leukemia/Lymphoma

United States, Australia, Canada
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Test the Effect of Cyclosporine on the Immune System of Patients With Early HIV Disease

HIV Infections

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Trial of Hetrombopag in Healthy Subjects

Sever Aplastic Anaemia

China
Masonic Cancer Center, University of Minnesota

Completed

Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia

Fanconi Anemia

United States
Safaa AA Khaled
Assiut University

Completed

Combination of Thrombopoietin Mimetic and Immunosuppressive Therapy in Aplastic Anaemia

Aplastic Anemia

Egypt
National Institute of Allergy and Infectious Diseases...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Clinical...

Completed

Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation

Diabetes Mellitus, Type I

Sweden, Norway
Assistance Publique - Hôpitaux de Paris
Merck Sharp & Dohme LLC; Pfizer; AbbVie; Société de Dermatologie Française; Janssen... and other collaborators

Completed

Assessing the Long Term Effectiveness and Safety of Biotherapies in the Treatment of Cutaneous Psoriasis (PSOBIOTEQ)

Psoriasis

France
National Cancer Institute (NCI)

Completed

Modified Stem Cell Transplant Procedure to Treat Patients With Blood and Immune System Cancers

Hematologic Neoplasms

United States
Imperial College London
Medical Research Council; Imperial College Healthcare NHS Trust; University Hospital...

Completed

Ciclosporin in HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) (HAM05)

HTLV I Associated Myelopathy

United Kingdom
Northwell Health

Completed

HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity

Sickle Cell Disease | Beta Thalassemia-Major

United States
Lee Dupuis
C17 Council

Completed

Pharmacological Predictors of Successful Cyclosporine Acute GVHD Prophylaxis in Children Undergoing HSCT

Acute-graft-versus-host Disease

Canada
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders

Non-Neoplastic Hematologic and Lymphocytic Disorder

United States
Monica Bhatia

Active, not recruiting

Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease

Sickle Cell Disease | Graft Versus Host Disease

United States
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)

Healthy Volunteer Study

Canada
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic Anemia

Aplastic Anemia

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

High-Dose Y-90-Ibritumomab Tiuxetan Added to Reduced-Intensity Allogeneic Stem Cell Transplant Regimen for Relapsed or Refractory Aggressive B-Cell Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Post-Transplant Lymphoproliferative Disorder | Recurrent Burkitt Lymphoma | Refractory Burkitt Lymphoma

United States
Aurinia Pharmaceuticals Inc.

Completed

Ocular Tolerability of Voclosporin Ophthalmic Solution Versus Restasis® in Subjects With Dry Eye Disease

Dry Eye

United States
Nohla Therapeutics, Inc.
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes

Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Acute Biphenotypic Leukemia | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission

United States
Hospital de Clinicas de Porto Alegre
University of Sao Paulo; Federal University of Rio Grande do Sul

Terminated

Cannabidiol as an Adjunctive Treatment for Bipolar Depression (CBDBD)

Bipolar Disorder | Bipolar Depression | Bipolar Affective Disorder

Brazil
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia

Severe Aplastic Anemia

United States
Fred Hutchinson Cancer Center

Withdrawn

Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation

Recurrent Hodgkin Lymphoma | Myelofibrosis | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Hematopoietic and Lymphoid System Neoplasm | Recurrent... and other conditions

United States
Stanford University

Completed

Allogeneic Transplantation Using Total Lymphoid Irradiation (TLI) and Anti-Thymocyte Globulin (ATG) for Older Patients With Hematologic Malignancies

Leukemia | Blood Cancer

United States
Robert Lowsky
National Cancer Institute (NCI)

Completed

CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma

Acute Myeloid Leukemia | Hodgkin Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | B-Cell Non-Hodgkin Lymphoma | Myeloproliferative Neoplasm | T-Cell Non-Hodgkin Lymphoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States

Search clinical trials for: CYCLOSPORINE

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