Search clinical trials for: CYP1A2 Inducer

Total 13444 results

Poznan University of Life Sciences

Completed

Personalized Nutrition Caffeine Intake in Healthy Adults.

CYP1A2 Polymorphism

Poland
University of Southern Denmark
Odense University Hospital

Completed

Uptake of the Antifungal Miconazole and Effect on Estrogen Metabolizing Enzymes in Humans

Healthy

Denmark
XiaoGuang Zou
Southern Medical University, China

Completed

Association Study Between CYP1A2 Gene Polymorphisms and Metabolism of Theophylline

Chronic Obstructive Pulmonary Disease

China
Theravance Biopharma

Completed

Drug-Drug Interaction (DDI) Study for TD-9855

Drug Drug Interaction (DDI)

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate Cancer

Prostate Cancer | Pharmacokinetics of Dextromethorphan | Pharmacokinetics of Caffeine

Moldova, Republic of
Zhujiang Hospital

Completed

Association Between CytochromeP4501A2 and CytochromeP4502E1 Gene Polymorphisms and Metabolism of Theophylline

Chronic Obstructive Pulmonary Disease

China
University of Southern Denmark
Odense University Hospital

Terminated

Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes

Cytochrome P450 Phenotype and Genotype Metrics

Denmark
AstraZeneca
Parexel

Completed

A Study to Assess the Effect of Fluvoxamine and Smoking on Pharmacokinetics ( the Movement of Drugs Within the Body) of AZD4635 in Healthy Volunteers

Healthy Volunteer/DDI Study

United Kingdom
University of Monastir

Completed

Clinical and Genetic Influencing Factors on Clozapine Pharmacokinetics

Schizophrenia | Clozapine | CYP1A2 Polymorphism | CYP2C19 Polymorphism

Tunisia
AstraZeneca
Parexel

Completed

A Study to Assess the Effects of Fluvoxamine on Savolitinib Exposure in Healthy Male Subjects

Healthy Male Subjects

United States
Affiliated Hospital of Nantong University

Not yet recruiting

CYP1A2, ABCB1, CYP2C9 and Plasma Concentration of Agomelatine in Adult Patients With Depression

Depression | Polymerase Chain Reaction | Polymorphism, Genetic | CYP1A2 Polymorphism | Plasma Concentration | CYP2C9 Polymorphism
Celgene

Completed

Food Effect and CYP1A2 Induction Study in Healthy Subjects

Healthy Volunteers

United States
Vanda Pharmaceuticals

Completed

Pharmacokinetics of Tasimelteon Alone and in Combination With CYP1A2 Inhibitor, Fluvoxamine

Healthy Volunteers

United States
Youssef Daali

Completed

Use of Endogenous Melatonin and 6-hydroxymelatonin as Biomarkers for CYP1A2 (MelaCYP)

Healthy

Switzerland
Abivax S.A.

Completed

Evaluation of the Potential CYP1A2-mediated Drug Drug Interaction Safety, and Tolerability of ABX464

Healthy

United Kingdom
Novartis Pharmaceuticals

Terminated

Safety and Pharmacokinetics of ASA404 When Given Together With Fluvoxamine, a Selective Serotonin Receptor Reuptake Inhibitor and CYP1A2 Inhibitor

Solid Tumors

United States
AstraZeneca

Completed

Effect of Multiple Doses of AZD6280 on the Pharmacokinetics of Midazolam (CYP3A4) and Caffeine (CYP1A2) (CYP)

Healthy

United Kingdom
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

The Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 Activity (FLUOXETINE)

Healthy Volunteers | Drug-Drug Interaction
MODAG GmbH
Teva Pharmaceutical Industries, Ltd.; Quotient Sciences; Aptuit

Completed

A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)

Healthy Volunteers

United Kingdom
AstraZeneca
Quintiles, Inc.

Completed

Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer

Solid Tumours

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

Advanced Solid Tumors, Excluding Breast Cancer

United States
Janssen Research & Development, LLC

Completed

A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9, and CYP1A2 Substrates

Healthy

Netherlands
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effect of Multiple Doses of LOXO-305 on the Pharmacokinetics of Single Oral Doses of CYP1A2, CYP2C9, CYP2C19 Substrates in Healthy Participants

Healthy

United States
R-Pharm International, LLC
IQVIA RDS Ireland Ltd; Thermo Fisher Scientific FS

Completed

Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4

Rheumatoid Arthritis

Bulgaria, Moldova, Republic of
Hadassah Medical Organization
United States - Israel Binational Science Foundation

Unknown

Evaluation of CYP2C9 Activity

Healthy

Israel
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Bioequivalence Study Of PHENYTOIN Suspension Made By Pfizer, Versus EPAMIN® Made By McNeil LA LLC In Healthy Volunteers Under Fasting Conditions

Healthy

Mexico
Beersheva Mental Health Center
The Rogosin Institute

Completed

Phenytoin as an Augmentation for SSRI Failures

Depression

Israel
Centre of Chinese Medicine, Georgia
Rea Rehabilitation Centre, Georgia

Completed

Study of Efficacy of Phenytoin in Therapy of Children With Bronchial Asthma

Bronchial Asthma

Georgia
Tehran University of Medical Sciences

Completed

Effect of Phenytoin on the Ganglion Cell Layer in Patients With Optic Neuritis

Optic Neuritis

Iran, Islamic Republic of
Radboud University Medical Center

Completed

The Effect of Phenytoin on the Pharmacokinetics of Nevirapine and the Development of Nevirapine Resistance (VITA 2)

Pregnancy | HIV-infection | Mother to Child Transmission

Zambia, Tanzania
Cairo University

Completed

Efficacy of Phenytoin Phonophoresis on Pressure Ulcer Healing

Pressure Ulcer

Egypt
Shahid Beheshti University of Medical Sciences

Unknown

Clinical Effect of Phenytoin Mucoadhesive Paste on Wound Healing After Oral Biopsy

Pain | Wound Healing

Iran, Islamic Republic of
Hadassah Medical Organization

Unknown

Determinants of Warfarin Metabolism

Healthy

Israel
Michael E. DeBakey VA Medical Center
Dr. Thomas A. Kent; Dr. Stacey Holmes; Dr. Su Bailey; Dr. Mark Kunik; Dr. Melinda...

Unknown

Pilot Trial of Neural Correlates of Response to Treatment of PTSD-Associated Impulsive Aggression

Posttraumatic Stress Disorder | Impulsive Aggression

United States
M. Carmen Cabellos Minguez
Hospital Clinic of Barcelona; Germans Trias i Pujol Hospital; Hospital Universitario... and other collaborators

Terminated

Study on the Efficacy of Phenytoin in the Prophylaxis of Seizures of Patients With Pneumococcal Meningitis at Least 50 Yrs Old.

Seizures | Pneumococcal Meningitis

Spain
National Institute on Drug Abuse (NIDA)
University of Minnesota

Completed

Effects of Phenytoin on Cocaine Use in Humans - 2

Cocaine-Related Disorders

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study to Assess if Epanutin Infatabs 50 mg From Germany Are Similar to Dilantin Infatabs 50 mg From Australia

Healthy

Singapore
David J. Kopsky
Princess Beatrix Muscle Foundation; Dr. C.J. Vaillant Fonds

Completed

Phenytoin Cream for the Treatment of Neuropathic Pain (EPHENE)

Chronic Idiopathic Axonal Polyneuropathy

Netherlands
University of Iowa

Completed

Phenytoin and Driving Safety: A Randomized, Controlled Cross-Over Study

Cognitive Measures | Driving Simulator Performance

United States
Shaheed Zulfiqar Ali Bhutto Medical University

Completed

Efficacy of Phenytoin vs Levetiracetam in Status Epilepticus at Institute of Child Health,Faisalabad

Status Epilepticus

Pakistan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Bioequivalence Study Of Phenytoin Suspension Versus Epamin® In 34 Healthy Volunteers.

Healthy

Mexico
Lawson Health Research Institute
UCB Pharma GmbH

Terminated

Comparative Trial of IV Lacosamide Versus Phenytoin for Seizure Management

Seizures

Canada
University College, London
National Multiple Sclerosis Society; Multiple Sclerosis Society of Great Britain...

Completed

Neuroprotection With Phenytoin in Optic Neuritis

Multiple Sclerosis | Optic Neuritis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Not yet recruiting

Pharmacological Management of Seizures Post Traumatic Brain Injury (MAST)

Traumatic Brain Injury | Post Traumatic Seizures
Children's Surgical Center, Cambodia

Unknown

Phenytoin in the Healing of Clean Surgical Wounds

Wound | Re-Epithelialization

Cambodia
Penn State University

Terminated

Dilantin Levels With Continuous Delivery of Enteral Feedings - A Pilot Study

Seizures
Bial - Portela C S.A.

Completed

Open-label Drug Interaction Study Between Eslicarbazepine Acetate and Phenytoin.

Epilepsy
Mylan Pharmaceuticals Inc

Completed

Steady-State Study of Extended Phenytoin Sodium Capsules 100 mg and Dilantin® Kapseals® 100 mg

Healthy

United States
Organon and Co

Completed

Quality of Life in Asthma and Rhinitis Allergic With Singulair (0476-365)

Asthma | Rhinitis Allergic
University of Massachusetts, Worcester
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Montelukast for Early Life Wheezing

Lung Diseases | Asthma

United States

Search clinical trials for: CYP1A2 Inducer

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