Search clinical trials for: Circulating Tumour DNA

Total 9887 results

Gene Solutions

Recruiting

Analysis of Circulating Tumor DNA Dynamics to Predict and Monitor Response to TKI in Patients With Advanced NSCLC.

Non Small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Stage IIIC Non-Small Cell Lung Cancer | Tyrosine Kinase Inhibitors

Vietnam
Gene Solutions

Recruiting

Investigate the Prognostic and Predictive Value of ctDNA During Neoadjuvant Chemotherapy for Breast Cancer.

Triple Negative Breast Cancer | HER2-positive Breast Cancer | Stage II Breast Cancer | Breast Cancer Female | Stage III Breast Cancer

Vietnam
University of Manchester
Cancer Research UK

Recruiting

Developing Circulating and Imaging Biomarkers Towards Personalised Radiotherapy in Lung Cancer (VIGILANCE)

Lung Cancer Stage III

United Kingdom
Erasmus Medical Center

Not yet recruiting

Can we Use a Simple Blood Test to Reduce Unnecessary Adverse Effects From Radiotherapy by Timely Identification of Radiotherapy-resistant Rectal Cancers? MeD-Seq Rectal Study

Pathological Response Rate, Circulating Tumour DNA
Centre Henri Becquerel

Not yet recruiting

Contribution of Residual Tumour DNA Testing on the Surgical Bed (MARGINS)

Squamous Cell Carcinoma of the Oral Cavity

France
Dr. Christopher Mueller
Canadian Institutes of Health Research (CIHR); Queen's University

Recruiting

Using a Blood Test to Monitor Metastatic Breast Cancer Treatment (BEACON)

Metastatic Breast Cancer

Canada
Royal Marsden NHS Foundation Trust

Recruiting

Exploratory Study of Early Biomarkers Allowing Dynamic Assessment of Response to Treatment in Cancers of the Head and Neck (DART)

Head and Neck Cancer

United Kingdom
RenJi Hospital
Peking University First Hospital; Xiangya Hospital of Central South University and other collaborators

Recruiting

Circulating Tumour DNA and Urine Tumor DNA Detection of Minimal Residual Disease in Locally Advanced Upper Tract Urothelial Carcinoma With Radical Nephroureterectomy: A Cohort Study

Muscle Invasive Upper Tract Urothelial Carcinoma

China
University of Edinburgh

Recruiting

The Role of Circulating Tumour DNA in Head and Neck Cancer

Oropharyngeal Squamous Cell Carcinoma | Human Papillomavirus (HPV)

United Kingdom
University Hospital, Antwerp
Universiteit Antwerpen

Recruiting

A Study to Evaluate the Value of Circulating Tumour DNA in Follow-up of Patients With an Advanced Gastroenteropancreatic or Lung Neuroendocrine Tumour Under Everolimus +- SSA Treatment (Liquid-NET 2.0)

Neuroendocrine Tumors

Belgium, Cyprus
Gene Solutions
Hanoi Medical University; Van Hanh General Hospital; Medical University of Ho... and other collaborators

Recruiting

Early Detection of Five Common Cancers Using the ctDNA Analysing Test (K-DETEK)

Cancer, Breast | Liquid Biopsy | Cancer, Lung | Cancer Liver | Cancer, Colorectal | Circulating Tumour DNA | Cancer, Gastric

Vietnam
Gruppo Oncologico del Nord-Ovest
Seagen Inc.; Servier; Foundation Medicine

Recruiting

Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients (ERASE-CRC)

Stage II Colon Cancer | Stage III Colon Cancer | HER2-positive Colon Cancer | RAS Wild-type Colon Cancer

Italy
National University Hospital, Singapore

Recruiting

Role of Circulating Tumour DNA Testing in Assessing for Alterations of Primary Anti-EGFR Resistance in RAS/RAF Wild-type Metastatic Colorectal Cancer Patients

Colorectal Cancer

Singapore
Royal Marsden NHS Foundation Trust
Pfizer; AstraZeneca; Institute of Cancer Research, United Kingdom; UNICANCER; Gustave... and other collaborators

Recruiting

A Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palbociclib Plus Fulvestrant Versus Standard Endocrine Therapy in Patients With ER Positive HER2 Negative Breast Cancer (TRAK-ER)

HER2-negative Breast Cancer | ER+ Breast Cancer

United Kingdom, France
Institut de Cancérologie de Lorraine

Recruiting

Personalized Circulating DNA Follow-up in Melanoma (PERCIMEL) (PERCIMEL)

Melanoma

France
Institut de Cancérologie de Lorraine

Recruiting

Bonds Between Circulating Tumoral ADN (ctDNA) and the Development of Peritoneal Carcinomatosis for Patients Under PIPAC (PIPADN)

Peritoneal Carcinomatosis

France
Fondazione Sandro Pitigliani
Clinical Research Technology S.r.l.

Recruiting

To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer (TIRESIAS)

Metastatic Breast Cancer | HER2-negative Breast Cancer | ER Positive Breast Cancer

Italy
Aarhus University Hospital

Recruiting

Selective Internal Radiation Therapy With 90Y Resin Micropheres for Refractory Colorectal Cancer Liver Metastases (SIRT)

Liver Metastasis Colon Cancer

Denmark
University Health Network, Toronto
Women's College Hospital; Jewish General Hospital; IWK Health Centre; British Columbia... and other collaborators

Recruiting

Cell-free DNA in Hereditary And High-Risk Malignancies (CHARM)

Hereditary Cancer Syndrome

Canada
Technische Universität Dresden

Recruiting

Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation (CIRCULATE)

Colon Cancer Stage II

Germany
British Columbia Cancer Agency

Recruiting

PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA (PROTRACT)

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Canada
Sichuan University
Geneplus-Beijing Co. Ltd.

Recruiting

A Prospective Study of Constructing Immune Repertoire to Monitor the Therapeutic Effect in NSCLC Patients

Non-small Cell Lung Cancer

China
Imperial College London

Recruiting

Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion (ctDNA)

Cancer | Rectal Cancer

United Kingdom
Anna Martling

Active, not recruiting

Circulating Tumour DNA (ctDNA) as a Prognostic and Predictive Marker in Colorectal Cancer - a Pilot Study (CITCCA)

Colorectal Cancer

Sweden, Norway
The Christie NHS Foundation Trust
Bristol-Myers Squibb; University of Manchester; Manchester Academic Health Science...

Active, not recruiting

CAcTUS - Circulating Tumour DNA Guided Switch (CAcTUS)

Melanoma

United Kingdom
Walter and Eliza Hall Institute of Medical Research
Johns Hopkins University

Active, not recruiting

Circulating Tumour DNA as a Marker of Residual Disease & Response to Adjuvant Chemotherapy in Stage I-IV Ovarian Cancer

Ovarian Cancer

Australia, United States
The Christie NHS Foundation Trust
University of Liverpool; University of Manchester; Manchester Academic Health...

Terminated

Circulating Tumour DNA guidEd Therapy for Stage IIB/C mElanoma After surgiCal resecTION (DETECTION)

Melanoma (Skin) | Melanoma, Stage II

United Kingdom
Universiteit Antwerpen
University Hospital, Antwerp; Kom Op Tegen Kanker

Completed

A Study to Evaluate the Value of Circulating Tumour DNA in Follow-up of Patients With an Advanced Gastroenteropancreatic or Lung Neuroendocrine Tumour Under Everolimus +- SSA Treatment (Liquid-NET)

Neuroendocrine Tumors

Belgium
The European Uro-Oncology Group
Centre for Human Drug Research, Netherlands

Completed

Imaging Staging and Response Prediction in Metastatic Hormono-Sensitive Prostate Cancer Patients Receiving Enzalutamide

Prostate Cancer Metastatic

Netherlands
The European Uro-Oncology Group
Centre for Human Drug Research, Netherlands

Completed

PET/CT and WB MRI for Staging and Response in CRPC Patients Receiving Enzalutamide

Prostate Cancer Metastatic

Netherlands
Institut de Cancérologie de Lorraine

Completed

Determination of the Feasibility of Tumoural Somatic Mutations Detection in Blood of Patients With Ovarian Cancer (BOVARY Pilot)

Ovarian Cancer

France
Institute of Cancer Research, United Kingdom
Merck Sharp & Dohme LLC; National Institute for Health Research Biomedical...

Active, not recruiting

A Trial Using ctDNA Blood Tests to Detect Cancer Cells After Standard Treatment to Trigger Additional Treatment in Early Stage Triple Negative Breast Cancer Patients (c-TRAK-TN)

Triple Negative Breast Cancer

United Kingdom
Lawson Health Research Institute

Completed

CIrculating Tumour DNA in Lung Cancer (CITaDeL): Optimizing Sensitivity and Clinical Utility (CITaDeL)

Lung Neoplasms | Lung Cancer | Non Small Cell Lung Cancer | Neoplasm of Lung

Canada
AstraZeneca

Completed

Study to Evaluate Concordance of Detecting EGFR (Epidermal Growth Factor Receptor) Mutation by Circulating Tumour Free DNA Versus Tissues Biopsy in NSCLC (Non-small Cell Lung Cancer). (CONCORDANCE)

NSCLC (Non-small Cell Lung Cancer)

India
Royal Marsden NHS Foundation Trust
University College, London; The Leeds Teaching Hospitals NHS Trust; Belfast Health... and other collaborators

Unknown

Targeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients. (TRAP)

Prostate Cancer | Metastasis | Toxicity Due to Radiotherapy | Circulating Tumour DNA

United Kingdom
CCTU- Cancer Theme
Cambridge University Hospitals NHS Foundation Trust; University of Cambridge

Unknown

LUCID - LUng Cancer CIrculating Tumour Dna Study (LUCID)

Non Small Cell Lung Cancer

United Kingdom
CCTU- Cancer Theme
AstraZeneca

Unknown

Cambridge Liquid Biopsy and Tumour Profiling Study for Patients on Experimental Therapeutics Trials (CALIBRATE)

Cancer

United Kingdom
University Health Network, Toronto

Completed

Use of Exome Sequence Analysis and Circulating Tumour in Assessing Tumour Heterogeneity in BRAF Mutant Melanoma

Melanoma

Canada
University Hospital, Rouen

Unknown

Correlation Between Circulating Tumour Markers Early Variations and Clinical Response in First Line Treatment of Metastatic Colorectal Cancer (COCA-MACS)

Metastatic Colorectal Cancer | Circulating Markers

France
British Columbia Cancer Agency
BC Cancer Foundation

Completed

The Oncopanel Pilot (TOP) Study

Gastrointestinal Stromal Tumors | Colorectal Cancer Metastatic | Advanced Melanoma | Advanced Non-Small Cell Lung Carcinoma | Patients With Diagnosed Malignancies Being Considered for Clinical Trials

Canada
University of Aarhus
Aarhus University Hospital

Recruiting

Circulating Tumor DNA in Peripheral T-cell Lymphomas (CIRCULATE)

Peripheral T-cell Lymphoma | NK/T-Cell Lymphoma

Denmark
Shanghai Chest Hospital

Recruiting

Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan

Carcinoma | Non-small Cell Lung Cancer

China
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; CGenetix

Not yet recruiting

Detection of Circulating Kidney DNA in Kidney Transplant Patients Facing an Episode of Graft Rejection (DART-RREGREF)

Kidney Transplant Patients Eligible for a Solid Biopsy
University Hospital, Basel, Switzerland

Not yet recruiting

Targeted Radionuclide Therapy in Metastatic Prostate Cancer Using a New PSMA Ligand Radiolabelled With Terbium-161 (161Tb-SibuDAB) - Dose Identification/Escalation Phase Ia/b Study (PROGNOSTICS)

Castration-resistant Prostate Cancer

Switzerland
Ohio State University Comprehensive Cancer Center

Recruiting

Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

United States
Zhujiang Hospital

Not yet recruiting

Value of Dynamic Monitoring of Early Recurrence of Hepatocellular Carcinoma After Radical Resection Based on CTCS

Recurrence | Hepatocellular Carcinoma | Surgery | Circulating Tumor Cell

China
Matteo's Friends

Recruiting

Dynamic Changes in Circulating Tumour Cells Protein Expression (Liquid-DRER2)

Recurrence Free Survival

Italy
Helse Nord-Trøndelag HF
Norwegian University of Science and Technology

Not yet recruiting

Circulating Tumor DNA in Patients Summoned for Colonoscopy; - a Liquid Biopsy for Detection, Characterization, Individualized Treatment and Follow-up of Colorectal Cancer (CoLiQ)

Colorectal Cancer | Colorectal Adenoma
Oslo University Hospital

Recruiting

Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced Malignancy

Metastatic Colorectal Cancer | Cholangiocarcinoma | Pancreas Adenocarcinoma

Norway
Interni hematologicka klinika FNKV
Charles University, Czech Republic; University Hospital Olomouc; General University... and other collaborators

Recruiting

Prognostic Significance of ctDNA in HL

Prognostic Cancer Model

Czechia

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