Search clinical trials for: Combinations of therapy

Total 437866 results

Juno Therapeutics, Inc., a Bristol-Myers Squibb...

Recruiting

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma

United States, Canada
University of Oxford

Not yet recruiting

A Study to Find Out if a Combination of 3 Medicines for the Treatment of Malaria Works as Well and is as Safe and Tolerable as Combinations of 2 Medicines (FD-TACT)

Uncomplicated Plasmodium Falciparum Malaria
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma

United States
Novartis Pharmaceuticals

Recruiting

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation (KontRASt-03)

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Colorectal Cancer | Non-Small Cell Lung Cancer | Nonsmall Cell Lung Cancer | Carcinoma, Non-Small Cell Lung | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal | Non-Small Cell Lung Carcinoma | KRAS G12C Mutant Solid Tumors

Korea, Republic of, Spain, Belgium, United States, France, Germany, Italy, Singapore
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany; Gilead Sciences; Nektar Therapeutics

Recruiting

A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)

Locally Advanced or Metastatic Urothelial Carcinoma

Korea, Republic of, United States, Taiwan, Australia, United Kingdom, France, Greece, Italy, Belgium, Spain, Canada, Denmark, Germany
National Taiwan University Hospital

Not yet recruiting

Phase Ib/II Trial of Combining Pembrolizumab and Lenvatinib With SBRT for HCC Patients With Portal Vein Thrombosis.

Unresectable Hepatocellular Carcinoma | Pembrolizumab | Stereotactic Body Radiotherapy | Lenvatinib

Taiwan
Centre Hospitalier Universitaire, Amiens

Recruiting

Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial (COMET)

Crohn Disease | Methotrexate | Azathioprine

France
Beijing Friendship Hospital
Xuanwu Hospital, Beijing; Beijing Chao Yang Hospital; Tianjin Medical University... and other collaborators

Recruiting

Neoadjuvant Chemoradiotherapy Plus Tislelizumab Followed by TME for LARC.

Colorectal Neoplasms

China
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Recruiting

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs. (DeTACT-Africa)

Plasmodium Falciparum Malaria (Uncomplicated)

Burkina Faso, Congo, The Democratic Republic of the, Gambia, Guinea, Nigeria, Niger, Rwanda, Tanzania
Toray Industries, Inc

Recruiting

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Solid Tumor | Cholangiocarcinoma | Bladder Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer | Palpable Subcutaneous Malignant Lesions

United States, France
Armed Forces Research Institute of Medical Sciences...
National Center for Parasitology, Entomology, and Malaria Control (CNM); Naval...

Recruiting

Drug Combinations of Atovaquone-Proguanil (AP) With ACT (APACT)

Plasmodium Falciparum Malaria (Drug Resistant)

Cambodia
Novartis Pharmaceuticals

Active, not recruiting

Study of NIS793 and Other Novel Investigational Combinations With SOC Anti-cancer Therapy for the 2L Treatment of mCRC (daNIS-3)

Metastatic Colorectal Cancer

Canada, Taiwan, Belgium, Germany, Spain, Italy, Czechia, Switzerland, Australia, United States, Japan, Singapore, United Kingdom, France, Israel, Hong Kong, Korea, Republic of
Royal College of Surgeons, Ireland
The Hospital for Sick Children; Imperial College London; Erasmus Medical Center; University College Dublin and other collaborators

Active, not recruiting

Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER) (RECOVER)

Cystic Fibrosis | Adherence, Medication | Cystic Fibrosis Gastrointestinal Disease | Cystic Fibrosis in Children | Cystic Fibrosis Liver Disease

United Kingdom, Ireland
Parker Institute for Cancer Immunotherapy
Bristol-Myers Squibb; Cancer Research Institute, New York City; Celldex Therapeutics and other collaborators

Completed

Platform Study for Prostate Researching Translational Endpoints Correlated to Response to Inform Use of Novel Combinations (PORTER)

Metastatic Castration-resistant Prostate Cancer

United States
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Active, not recruiting

S095029 as Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies Followed by an Expansion Part With Triple Combinations in Patients With Metastatic Gastric or Colorectal Cancers

Solid Tumor

United States, Canada
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Completed

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia) (DeTACT-ASIA)

Plasmodium Falciparum Malaria (Uncomplicated)

Cambodia, Bangladesh
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma

United States
Fundação Educacional Serra dos Órgãos

Completed

Evaluation of Aminobutyric Acid, Glutamic Acid, Calcium, Thiamine, Pyridoxine and Cyanocobalamin as Therapy for Vertigo

Vertigo

Brazil
Bristol-Myers Squibb
AbbVie

Completed

An Investigational Immuno-therapy Study of Nivolumab, Pomalidomide and Dexamethasone Combinations in Patients With Multiple Myeloma (CheckMate 602)

Multiple Myeloma

Canada, United States, Israel, Czechia, Switzerland, Greece, Denmark, Portugal, Italy, Germany, Austria, Norway, Puerto Rico, Spain, Sweden, Turkey
AbbVie
Idera Pharmaceuticals, Inc.

Completed

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Advanced Solid Tumors Cancer

United States, France, Germany, Israel, Netherlands, Spain
Bristol-Myers Squibb

Completed

An Adaptive Study to Match Patients With Solid Tumors to Various Immunotherapy Combinations Based Upon a Broad Biomarker Assessment (ADVISE)

Advanced Cancer

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used Indinavir

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Three Anti-HIV Drug Combinations in Patients Who Have Taken Amprenavir

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Comparison of New Anti-HIV Drug Combinations in HIV-Infected Children Who Have Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients With No Symptoms of the Disease

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy

HIV Infections

United States, Puerto Rico, Tanzania
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety and Effectiveness of Four Anti-HIV Drug Combinations in HIV-Infected Children and Teens

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb

Completed

The Effectiveness of Three Drug Combinations in HIV-Infected Patients Who Have Taken Zidovudine for More Than 12 Weeks

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Three Treatment Combinations Using Zidovudine Plus Lamivudine Plus Indinavir in HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Treatment With Combinations of Several Antiviral Drugs in Infants and Young Children With HIV Infection

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Dual Versus Triple Protease Inhibitor Combinations, Including Ritonavir, in HIV Infected People

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDS

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Tanzania
National Institute of Allergy and Infectious Diseases...

Completed

Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Never Used Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

The Effects of Staggered Dosing on Interactions Between Paired Combinations of Nelfinavir, Ritonavir, and Saquinavir

HIV Infections

United States
VA Office of Research and Development

Completed

Selecting Effective Combinations of Treatment for Low Back Pain (SELECT LBP)

Low Back Pain

United States
University of California, San Francisco
San Francisco AIDS Foundation; California HIV/AIDS Research Program

Completed

Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy (I-BrEATHe)

HIV Prevention | Transgender Health

United States
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (ATLAS)

Nonalcoholic Steatohepatitis

Hong Kong, United States, Australia, Puerto Rico, New Zealand, Canada
Chiesi Farmaceutici S.p.A.

Completed

Efficacy and Tolerability of Beclomethasone Dipropionate 100 µg + Formoterol 6 µg pMDI Via HFA-134a Vs. Budesonide 160 µg + Formoterol 4,5 µg Dry Powder Via Turbuhaler®. (Symbicort®)

Bronchial Asthma

Austria, Poland, Ukraine
Chiesi Farmaceutici S.p.A.

Completed

EFFICACY AND TOLERABILITY OF BECLOMETHASONE DIPROPIONATE 100 µg + FORMOTEROL 6 µg pMDI VIA HFA-134a vs. FLUTICASONE 125 µg + SALMETEROL 25 µg pMDI

Bronchial Asthma

Poland, Ukraine
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Longitudinal Antimalarial Combinations in Uganda

Malaria

Uganda
KU Leuven

Unknown

Systematic Approach for the Diagnosis and Treatment of Obstructive Lung Diseases (ACOS)

Chronic Obstructive Pulmonary Disease | Asthma | Overlap Syndrome

Belgium
GlaxoSmithKline

Completed

A Clinical Study Assessing Critical Errors, Training/Teaching Time, and Preference Attributes of the ELLIPTA® Dry Powder Inhaler, in Comparison to Combinations of Dry Powder Inhalers Used to Provide Triple Therapy, in Patients With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United Kingdom, Netherlands
Seng Gee Lim
Merck Sharp & Dohme LLC; Singapore General Hospital; Tan Tock Seng Hospital; Changi... and other collaborators

Completed

Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy (SWAP)

Chronic Hepatitis B

Singapore
Takeda

Terminated

Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical Practice

Diabetes Mellitus, Type 2

China, Hong Kong
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings (PEARLS)

HIV Infections

United States, Brazil, Peru, India, Malawi, Haiti, South Africa, Thailand, Zimbabwe
Huashan Hospital

Unknown

Efficiency of Budesonide Combined With Formoterol and Tiotropium in the Treatment of Acute Exacerbation of ACO

Asthma-COPD Overlap
National Taiwan University Hospital

Unknown

Combinations of Oral Appliance and CPAP for Patients With Severe Obstructive Sleep Apnea Untolerate High-pressure CPAP

Obstructive Sleep Apnea
Gilead Sciences

Completed

Part A: Drug Interaction Study of Sofosbuvir and Antiretroviral Therapy (ART) Combinations in HIV and Hepatitis C Virus (HCV) Co-infected Patients. Part B: Efficacy and Safety of Sofosbuvir for 12 Weeks in HIV/HCV Co-infected Patients.

Hepatitis C | HIV

Puerto Rico
Almirall, S.A.

Completed

A Single-dose, Randomised, Crossover, Placebo-controlled Study Assessing Two Fixed-dose Combinations of Inhaled Long-acting Beta-agonist and Corticosteroid

Asthma

Germany, United Kingdom

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