Search clinical trials for: Cyclic Guanylyl Monophosphate Pathway

Total 1693 results

Thomas J. Wang, MD

Completed

A Trial of Tadalafil and Glycemic Traits

Obesity | Cardiovascular Disease | Insulin Resistance | Glucose Intolerance

United States
University of Alabama at Birmingham

Not yet recruiting

VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway (VITAL-IMPACT)

Cardiovascular Diseases | Obesity | Insulin Sensitivity/Resistance | Metabolic Disease | Energy Expenditure | Metabolism

United States
Hannover Medical School
Pharmacia

Completed

Effects of Growth Hormone on the Nitric Oxide Pathway

Cardiovascular Disease

Germany
Holland Bloorview Kids Rehabilitation Hospital
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Home Exercise Program Using Bootle Boot Camp

Cerebral Palsy

Canada
Centre Hospitalier Régional d'Orléans

Recruiting

Exploration of the Activity of DNA Located Outside of Cellular Nucleus to Amplify Inflammation in Inflammatory Bowel Disease in Children Through Biological Pathway Cyclic GMP-AMP Synthase (cGAS) - Stimulator of Interferon Genes (STING) (ROXANE)

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis

France
University of Nebraska

Recruiting

HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction

HFpEF - Heart Failure With Preserved Ejection Fraction

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
United States Department of Defense

Active, not recruiting

Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer

Colorectal Adenoma | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC v8 | Stage 0 Colorectal Cancer AJCC v8 | Stage I Colorectal Cancer AJCC v8 | Stage II Colorectal Cancer AJCC v8 | Stage IIA Colorectal... and other conditions

United States
Boehringer Ingelheim

Completed

Assessment of Exposure of BI 409306 in Cerebrospinal Fluid (CSF) Relative to Plasma as Well as to Evaluation of the Effect of Different Doses of BI 409306 on the cGMP (Cyclic Guanosine Monophosphate) Levels in CSF in Healthy Male Volunteers

Healthy

Belgium
Sidney Kimmel Cancer Center at Thomas Jefferson...
National Cancer Institute (NCI)

Completed

Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

Follicular Lymphoma | Myeloid Leukemia | Polycythemia Vera | Hodgkin Lymphoma | Myelofibrosis | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Chronic Lymphocytic Leukemia | Secondary Acute Myeloid Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Refractory... and other conditions

United States
University of California, San Francisco
Ann & Robert H Lurie Children's Hospital of Chicago; Children's Hospital Los...

Terminated

Chronic Sildenafil for Severe Diaphragmatic Hernia

Hernia, Diaphragmatic | Hypertension, Pulmonary | Hypoplasia, Pulmonary

United States
Inland Norway University of Applied Sciences

Completed

Effects of Including Sprints During Low-intensity Cycling Exercises on Performance and Muscle/Blood Characteristics

Healthy | Cyclists

Norway
Origin Biosciences

Completed

A Retrospective, Observational, Noninterventional Data Collection Study for Patients With Molybdenum Cofactor Deficiency Who Have Been Previously Treated With Cyclic Pyranopterin Monophosphate (cPMP)

Molybdenum Cofactor Deficiency

United States, Australia, United Kingdom, Germany, Netherlands, Turkey
The University of Texas Medical Branch, Galveston

Completed

The Effect of Sildenafil and Tadalafil on Skeletal Muscle and Perceptual Fatigue

Fatigue

United States
University of Konstanz
University of Stellenbosch; University of Cape Town

Completed

Treatment of Trauma and Violence in the Townships of South Africa

Aggressive Behavior | Post-traumatic Stress Disorder (PTSD)

South Africa
Greg Davis

Completed

Olfactory Dysfunction of Rhinosinusitis - Cyclic Adenosine Monophosphate (cAMP)/Calcium Signaling Study (cAMP)

Sinusitis

United States
University of Washington

Completed

cAMP (Cyclic Adenosine Monophosphate) Levels in the Nose

Olfactory Disorder

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

Tocladesine in Treating Patients With Recurrent or Progressive Metastatic Colorectal Cancer

Colorectal Cancer

United States
Northwestern University
National Cancer Institute (NCI)

Completed

Tocladesine in Treating Patients With Recurrent or Refractory Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
Horng Chen
National Heart, Lung, and Blood Institute (NHLBI); National Center for Research...

Completed

Natriuretic Peptide System as Therapy in Human Preclinical Left Ventricle Dysfunction (PPG1)

Congestive Heart Failure

United States
Orphatech Pharmaceuticals, GmbH

Withdrawn

Study of cPMP (Precusor Z) to Treat Molybdenum Cofactor Deficiency (MoCD) Type A

Molybdenum Cofactor Deficiency Type A

Australia
Basque Health Service
Health Department of the Basque Government

Recruiting

Asthma Crisis in Paediatrics: Impact of a Care Pathway in Primary and Hospital Care

Asthma in Children | Implementation Science | Inappropriate Prescribing

Spain
Xie Kangjie

Recruiting

Predictive Effect of TGF-β Combined With INS-PI3K-AKT Signaling Pathway Related Proteins (ADNP, MAP6, Pgc-1α) for POD on Diabetes Patients

Diabetes | Postoperative Delirium

China
Mayo Clinic

Recruiting

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Cholangiocarcinoma | Refractory Cholangiocarcinoma | Stage III Hilar Cholangiocarcinoma AJCC v8 | Stage IV Hilar Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
Hitit University

Recruiting

Schroth Treatment and Proprioception Pathway

Adolescent Idiopathic Scoliosis

Turkey
University of Alberta

Not yet recruiting

Pharmacist Case Finding and Intervention for Vascular Prevention Trial (PRxOACT)

Cardiovascular Disease | Diabetes | Dyslipidemia | Blood Pressure | Cardiovascular Risk Factors
Greg O'Grady
University of Auckland, New Zealand

Not yet recruiting

Validation of a Mental Health Scale for Young People With Chronic Stomach Symptoms

Dyspepsia | Nausea | Vomiting | Rumination Syndrome | Functional Gastrointestinal Disorders | Gastroparesis | Aerophagy | Vomiting; Cyclical
Assistance Publique Hopitaux De Marseille

Recruiting

Prospective Multicenter Cohort Study to Validate Four Groups of Biomarkers for Assessing Lung Cancer Risk Among Patients With Atheromatous Cardiovascular Disease in a Screening Pathway (BIOCEPTION)

Lung Cancer | Smoking-related Pathology | Atheroma | Non-progressive Cancer > 5 Years

France
The Cleveland Clinic

Not yet recruiting

Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes (OPUS)

Prenatal Disorder

United States
Mayo Clinic

Not yet recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
University of Alberta
Alberta Innovates Health Solutions

Not yet recruiting

Digital Health Pathway for Children With Medical Complexity Requiring Tracheostomy (DECIDE-T)

Tracheostomy

Canada
Stony Brook University
Massachusetts General Hospital; Mclean Hospital

Recruiting

Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder

Bipolar Disorder | Bipolar Disorder Type 1

United States
University Hospital, Toulouse
Janssen, LP; Ligue contre le cancer, France

Not yet recruiting

Real-life Management of Patients Eligible for CAR-T Cell Therapy (CARAVAGE)

Hemopathy

France
Hospital Pediátrico de Sinaloa

Recruiting

Parenteral Nutrition Cycling for Prevention of Cholestatic Syndrome in Newborn

Cholestasis in Newborn

Mexico
Medical College of Wisconsin

Not yet recruiting

Molecular Analyses to Identify Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

Breast Cancer

United States
University of Alabama at Birmingham

Not yet recruiting

Establishment of an Interdisciplinary Functional Neurological Disorder (FND) Treatment Program and Development of a Clinical Care Pathway for FND

Convulsion, Non-Epileptic | Functional Neurological Disorder | Functional Seizure

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

Non-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle Deregulation

China
Chinese University of Hong Kong

Not yet recruiting

To Evaluate an MRI-based Optimized Prostate Cancer Diagnostic Pathway Powered by Artificial Intelligence

Prostate Cancer

Hong Kong
Institut Jean-Godinot
Université de Reims Champagne-Ardenne

Not yet recruiting

Development of a Questionnaire on Patients' Perception of Their Oncology Care Pathway (Onco-PREMs) (OncoPREMs)

Cancer
University of Michigan
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Guideline to Implementation: A Rapid Clinical Care Pathway to Care for Patients Affected by Chronic Constipation

Constipation

United States
Karolinska University Hospital

Not yet recruiting

Metabolic Pathway Analysis in Intensive Care Unit Patients With Refeeding Syndrome

Critical Illness | Hypophosphatemia | Refeeding Syndrome

Sweden, Czechia, Italy
Elsan

Not yet recruiting

Innovative Care Pathway in Physical Activity and Behavior Change in Coronary Patients Post-cardiac Rehabilitation (APIC)

Individualised Physical Activity Program | Coronary Patient
Pr. Nicolas GIRERD

Recruiting

PAtient Treatment Analysis: Hospital and Wide-ranging Out-of-hospital Care Assessment Yields Insights Into Heart Failure Outcomes (PATHWAY-HF)

Heart Failure

France
University of Alberta
Alberta Health services

Recruiting

Optimizing the Management of Staphylococcus Aureus Bacteremia (OPTIMUS-SAB)

Staph Aureus Bacteremia

Canada
Fondazione del Piemonte per l'Oncologia

Recruiting

INSIDE: Identification of Genomic Screening Pathways in Cancer Patients With DNA Repair Alterations (INSIDE)

Prostate Cancer

Italy
Ziauddin University

Not yet recruiting

Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial (MROSF)

Oral Submucous Fibrosis

Pakistan
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Effect of RAS/MAPK Pathway Hyperactivation on Growth' and Bone' Profile of the RASopathies (3776)

Noonan Syndrome | Costello Syndrome | RASopathy | Cardio-Facio-Cutaneous Syndrome

Italy
University of Edinburgh

Not yet recruiting

Objective Risk Assessment in Patients With Possible Anginal Chest Pain Using Leading Technology (ORACLE)

Coronary Artery Disease | Angina, Stable
Nested Therapeutics, Inc

Recruiting

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors (NST-628)

Glioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene Mutation

United States, Australia
Black Hills State University
National Institute of General Medical Sciences (NIGMS)

Not yet recruiting

Examination of Psychological and Physiological Pathways Linking Gratitude and Pain

Acute Pain | Emotions | Positive Thinking
Beijing Anzhen Hospital

Not yet recruiting

Efficacy of Pharmacist Interventions Through the "Medication Therapy Management Pathway in Hypertensive Patients" (PharmMTMH)

Hypertension | Medication Therapy Management

China

Search clinical trials for: Cyclic Guanylyl Monophosphate Pathway

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