Search clinical trials for: Cystic Fibrosis Transmembrane Conductance Regulator

Total 7003 results

Hospices Civils de Lyon

Not yet recruiting

Circadian Rhythm Disorders in Children With Cystic Fibrosis Under CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Modulators (CHRONO-MUCO)

Cystic Fibrosis

France
Universitair Ziekenhuis Brussel

Not yet recruiting

Real-world Efficacy and Safety of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulator Therapy in Adult Patients With Cystic Fibrosis (CF)

Cystic Fibrosis
University of British Columbia

Recruiting

Canadian Observational Study Evaluating the Long-term IMPACT of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators on People With CF (Can-IMPACT CF)

Cystic Fibrosis

Canada
University Hospitals Cleveland Medical Center

Recruiting

Evaluation of Lung T1-MRI in Pediatric Cystic Fibrosis Patients

Cystic Fibrosis

United States
Cliniques universitaires Saint-Luc- Université...
Université de Liège

Recruiting

New Markers of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function in Sweat

Cystic Fibrosis | Biomarkers

Belgium
Children's Hospital Medical Center, Cincinnati

Active, not recruiting

Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis

Cystic Fibrosis

United States
Ciusss de L'Est de l'Île de Montréal
Juvenile Diabetes Research Foundation; Institut de Recherches Cliniques de...

Completed

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Exocrine Pancreatic Dysfunction in Type 1 Diabetes

Type 1 Diabetes | Exocrine Pancreatic Insufficiency

Canada
Children's Hospital of Philadelphia
Vertex Pharmaceuticals Incorporated

Completed

Ivacaftor Treatment in 4 Month to 2 Year Old CF Subjects

Cystic Fibrosis

United States
Novartis Pharmaceuticals

Terminated

Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients

Cystic Fibrosis

United States, Belgium, Germany, France, United Kingdom, Ireland, Romania
Insmed Incorporated

Completed

Extension Study of Liposomal Amikacin for Inhalation in Cystic Fibrosis (CF) Patients With Chronic Pseudomonas Aeruginosa (Pa) Infection

Cystic Fibrosis

France, Poland, United Kingdom, Germany, Spain, Belgium, Bulgaria, Serbia, Denmark, Greece, Netherlands, Hungary, Ireland, Slovakia, Canada, Italy, Austria
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study to Evaluate the Efficacy and Safety of Ivacaftor and VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mutation

Cystic Fibrosis

United States, Australia, Canada, Germany, Switzerland, Israel, Netherlands, Belgium, Italy, United Kingdom, France
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

Cystic Fibrosis

United States, Canada, Germany, United Kingdom
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Roll-Over Study of Ivacaftor in Cystic Fibrosis Pediatric Subjects With a CF Transmembrane Conductance Regulator Gene (CFTR) Gating Mutation

Cystic Fibrosis

United States, United Kingdom, Canada
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-809 in Cystic Fibrosis Subjects With the ∆F508-CFTR Gene Mutation

Cystic Fibrosis

United States, Belgium, Canada, Netherlands, Germany
Assistance Publique - Hôpitaux de Paris

Terminated

Interest of Gentamicin-induced Readthrough in Cystic Fibrosis Patients

Cystic Fibrosis

France
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of Ivacaftor in Subjects With Cystic Fibrosis (CF) Who Have the R117H-CF Transmembrane Conductance Regulator (CFTR) Mutation (KONDUCT) (KONDUCT)

Cystic Fibrosis

United States, United Kingdom
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of Ivacaftor in Subjects With Cystic Fibrosis (CF) Who Have a Non-G551D CF Transmembrane Conductance Regulator (CFTR) Gating Mutation (KONNECTION)

Cystic Fibrosis

United States, France, Belgium
CF Therapeutics Development Network Coordinating...
Cystic Fibrosis Foundation

Completed

Detection of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity in Rectal Tissues From Human Subjects

Cystic Fibrosis

United States
University of Alabama at Birmingham
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Phase I Study of Liposome-Mediated Gene Transfer in Patients With Cystic Fibrosis

Cystic Fibrosis
Actelion

Terminated

Miglustat / OGT 918 in the Treatment of Cystic Fibrosis

Cystic Fibrosis

Spain
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Phase I Pilot Study of Ad5-CB-CFTR, an Adenovirus Vector Containing the Cystic Fibrosis Transmembrane Conductance Regulator Gene, in Patients With Cystic Fibrosis

Cystic Fibrosis
Charite University, Berlin, Germany
Hannover Medical School; Heidelberg University; University of Giessen

Recruiting

Cystic Fibrosis Transmembrane Regulator (CFTR) Biomarker Study to Evaluate the Rescue of Mutant CFTR in Patients With Cystic Fibrosis Treated With CFTR-modulators (Modulate-CF)

Cystic Fibrosis

Germany
Qanatpharma Canada LTD

Completed

Bioequivalence and Food Effect Bioavailability Study of Lumacaftor Film-Coated Tablets

Healthy Volunteer

Canada
University of Alabama at Birmingham
National Institutes of Health (NIH)

Completed

Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators

Cystic Fibrosis

United States
Children's Hospital Los Angeles

Not yet recruiting

Maralixibat in Patients With Cystic Fibrosis and Constipation, A Within-Subjects Pilot Study

Cystic Fibrosis | Constipation Chronic Idiopathic

United States
Ospedale San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Recruiting

Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis (BioMol-MA)

Non-Tuberculous Mycobacterial Pneumonia | Cystic Fibrosis Lung

Italy
Groupe Hospitalier de la Region de Mulhouse et...

Not yet recruiting

Frequency-time Analysis of Pathological Lung Sounds: Detection and Quantification of Pathological Sounds in Patients With Cystic Fibrosis, Pulmonary Fibrosis or COPD (Chronic Obstructive Pulmonary Disease) (ATF/SPP)

Chronic Obstructive Pulmonary Disease | Pulmonary Fibrosis | Cystic Fibrosis
Centre Hospitalier Universitaire de la Réunion

Recruiting

Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis (ACHROMO-MUCO)

Cystic Fibrosis

Réunion
Centre Hospitalier Intercommunal Creteil
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis (ANTEIPA)

Bronchiectasis

France
University of Kansas Medical Center

Not yet recruiting

Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.

Cystic Fibrosis

United States
Assistance Publique - Hôpitaux de Paris
Vaincre la Mucoviscidose

Not yet recruiting

Oral Health Status of Cystic Fibrosis Patients. An Online Survey in Collaboration With the Vaincre la Mucoviscidose Patient Association. (E-MUCODENT)

Cystic Fibrosis

France
Assiut University

Not yet recruiting

Procalcitonin as a Marker of Severity of Non-cystic Fibrosis Bronchiectasis in Children

Non-cystic Fibrosis Bronchiectasis
Emory University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

A Pilot and Feasibility Study to Evaluate High vs Low Glycemic Index Mixed Meal Tolerance Test in Adolescents and Young Adults With Cystic Fibrosis

Cystic Fibrosis

United States
Centre Hospitalier Intercommunal Creteil

Not yet recruiting

Real World Environmental Exposure Study With Healthy and Cystic Fibrosis Subjects (ExpoCF)

Environmental Exposure | Cystic Fibrosis, Pulmonary | Exhaled Breath Condansate
Children's Hospital Medical Center, Cincinnati

Recruiting

Regional Monitoring of CF Lung Disease

Cystic Fibrosis

United States
University Hospital, Strasbourg, France

Not yet recruiting

Effect of One Year Elexacaftor-tezacaftor-ivacaftor Treatment (DIATRIM)

Cystic Fibrosis
Pole Sante Grace de Dieu

Recruiting

Improving the Well-being of Caregivers of Cystic Fibrosis Patients During Physiotherapy Treatment (MucoZar)

Cystic Fibrosis

France
Universidad Politecnica de Madrid
Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Hospital Universitario... and other collaborators

Recruiting

Exercise in People With Cystic Fibrosis on CFTR Modulator Therapy (FIQMODE)

Cystic Fibrosis

Spain
Daniel J. Weiner

Recruiting

Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis

Cystic Fibrosis

United States
University of Valencia
Asociación de Fibrosis Quística - Comunidad Valenciana

Not yet recruiting

e-Health Program to Prevent Exacerbations in the Cystic Fibrosis Population

Cystic Fibrosis

Spain
Halic University

Recruiting

Effect of Parental Attitude on Functional and Physical Level of Children With Cystic Fibrosis

Cystic Fibrosis | Cystic Fibrosis in Children

Turkey
Vertex Pharmaceuticals Incorporated

Recruiting

A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulation of Vanzacaftor/Tezacaftor/Deutivacaftor(VNZ/TEZ/D-IVA)

Cystic Fibrosis

United States
Hôpital Necker-Enfants Malades

Not yet recruiting

Assessment of Patients Not Concluded After Neonatal Screening of Cystic Fibrosis.

CFTR-RD
Region Stockholm
Karolinska Institutet

Recruiting

CFTR Modulators in Pregnancy and Postpartum

Cystic Fibrosis

Sweden
University of Pittsburgh
National Heart, Lung, and Blood Institute (NHLBI); Cystic Fibrosis Foundation

Recruiting

Health Outcomes of Parents With Cystic Fibrosis-Aim 2 (HOPeCF)

Cystic Fibrosis | Parenthood Status

United States
Halic University

Recruiting

Development,Validity and Reliability of a Caregiver Version of the Breathlessness Beliefs Questionnaire

Cystic Fibrosis | Parents

Turkey
Oslo University Hospital

Recruiting

Quality of Life and Gut Health in Pediatric Patients With Cystic Fibrosis

Cystic Fibrosis in Children

Norway
Kirsehir Ahi Evran Universitesi
TC Erciyes University

Not yet recruiting

An Intervention-Based Approach to Strengthen the Psychological Health of Children With Cystic Fibrosis and Their Mothers

Children | Cystic Fibrosis | Lung Functions | Mothers | Laughter Yoga | Laughter Therapy | Resilience,Psychological | Psychological Health

Turkey
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis

Bronchiectasis

United Kingdom, United States, Israel
Pilar Azevedo
Queen's University, Belfast; Medical University Innsbruck; Cystic Fibrosis Foundation and other collaborators

Recruiting

COVID-19 Antibody Responses In Cystic Fibrosis (CAR-CF)

COVID-19 | Cystic Fibrosis

Portugal

Search clinical trials for: Cystic Fibrosis Transmembrane Conductance Regulator

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