Search clinical trials for: Cytochrome p 450 cyp2c19

Total 494167 results

Indiana University

Terminated

IU Health Krannert Personalized Medicine Study

Coronary Artery Disease

United States
Pfizer

Completed

Open Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Aripiprazole When Coadministered To Healthy Subjects

Pharmacokinetics | Cytochrome P-450 CYP2D6 | CYP3A4 Protein, Human

United States
University of Belgrade
Clinical Centre of Serbia; Military Medical Academy, Belgrade, Serbia; Institute...

Recruiting

Personalized Sertraline Dosing in Patients With Depression (PsyCise-S)

Depressive Disorder, Major

Serbia
University of Belgrade
Clinical Centre of Serbia; Military Medical Academy, Belgrade, Serbia; Institute...

Recruiting

Personalized Escitalopram Dosing in Patients With Depression (PsyCise-E)

Depressive Disorder, Major

Serbia
Mahidol University

Unknown

Influence of Cytochrome P2B6 on Efavirenz Dose in HIV-infected Thai Patients

HIV | Cytochrome P-450 CYP2B6 | Efavirenz

Thailand
University of Southern Denmark

Completed

Impact of CYP2C19*17 on the Pharmacokinetics of Proguanil and Clopidogrel

CYP2C19 Genotypes

Denmark
AstraZeneca

Completed

Study in Taiwanese Subjects Identified as CYP2C19 Poor and Extensive Metabolizers Receiving Rosuvastatin

CYP2C19 Poor | Extensive Metabolizers

Taiwan
Stanford University

Recruiting

CYP2C19 Variants and Limonene Metabolism

CYP2C19 Genetic Variants

United States
Beijing Anzhen Hospital

Unknown

The Influence of Gene Polymorphism on Clinical Outcomes in Patients Undergoing PCI

Antiplatelet Therapy | CYP2C19 Polymorphism

China
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Pharmacogenetic and Pharmacokinetics of Naproxen and Associated Naproxen-esomeprazole

Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant

Brazil
Javeriana University
Universidad Nacional de Colombia

Completed

Effect of the CYP2C19 Polymorphism in Helicobacter Pylori Eradication

Therapy | H.Pylori Infection | CYP2C19 Polymorphism
Studies&Me
Bispebjerg Hospital; Biotx.ai; Life&Brain; Stanford Health Care

Withdrawn

Using a Telemedicine Approach in a Genome-wide Association Study of Atopic Dermatitis - Searching for Novel Biomarkers in Clinically Relevant Phenotypes

Eczema | Atopic Dermatitis | DNA

United States, Denmark
Genelex Corporation
University of Utah

Completed

YouScript IMPACT Registry (IMPACT)

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme Deficiency | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome... and other conditions

United States
Xinjiang Medical University

Completed

Personalized Antiplatelet Therapy in CAD Patients

Coronary Artery Disease
University of Southern Denmark
Odense University Hospital

Terminated

Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes

Cytochrome P450 Phenotype and Genotype Metrics

Denmark
Seoul National University Hospital

Completed

Influence of SLCO2B1 Polymorphism on the PK of Voriconazole in CYP2C19 PM

Healthy Volunteers

Korea, Republic of
Bio-Signal Group Corp.
National Institute of Neurological Disorders and Stroke (NINDS); State University... and other collaborators

Completed

Putting Electroencephalography (EEG) in the Emergency Department

Altered Mental Status | Generalized Nonconvulsive Seizure Disorder | Status-epilepticus

United States
Genelex Corporation
Harding University

Completed

Pharmacogenetic Testing Among Home Health Patients

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme... and other conditions

United States
Gyeongsang National University Hospital

Unknown

Comparison of Platelet Inhibition With Adjunctive Cilostazol Versus High Maintenance-Dose Clopidogrel According to Hepatic Cytochrome 2C19 Allele (CYP2C19) Polymorphism (ACCEL2C19)

Coronary Artery Stenosis | Maximal Platelet Aggregation | Late Platelet Aggregation | High Post-Treatment Platelet Reactivity

Korea, Republic of
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

Effect of Rifampin and Efavirenz on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects

Healthy Volunteers

United States
Memorial Sloan Kettering Cancer Center
Bayer

Completed

A Study of Copanlisib and Ibrutinib in Mantle Cell Lymphoma

Mantle Cell Lymphoma (MCL)

United States
Pfizer

Completed

Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants

Healthy Volunteers | Adult | Drug Interactions | Humans

Belgium
Taichung Veterans General Hospital

Completed

The Protective Effect of Omega-3 Fatty Acid on Cognitive Function Among Patients With Mild Dementia

Alzheimer Disease | Dementia Disorder

Taiwan
Hospital Italiano de Buenos Aires

Completed

Sepsis Institutional Registry in Hospital Italiano de Buenos Aires (SIR)

Death | Severe Sepsis

Argentina
Hospital Italiano de Buenos Aires
Salumedia Tecnologias

Unknown

Gamifying Patient's Personal Data Validation and Completion in a Personal Health Record

Chronic Disease

Argentina
Asan Medical Center

Unknown

A Genotype Stratification Study for Pharmacokinetics and Pharmacodynamics of Amitriptyline in Healthy Male Subjects

Depression
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Children

HIV Infections | Tuberculosis

South Africa, Zimbabwe, India, Uganda
Alexion Pharmaceuticals

Completed

Drug Interaction Study of ALXN2050 With Fluconazole and Rifampin in Healthy Adult Participants

Healthy

United States
Spartan Bioscience Inc.
Mount Sinai Services

Completed

Spartan Cube CYP2C19 Method Comparison Study

Genotyping Techniques

Canada
University of Monastir

Completed

Clinical and Genetic Influencing Factors on Clozapine Pharmacokinetics

Schizophrenia | Clozapine | CYP1A2 Polymorphism | CYP2C19 Polymorphism

Tunisia
Synermore Biologics Co., Ltd.
inVentiv Health Clinical

Completed

A Comparison of the Safety, PD and PK of a Single Dose of SYN023 Administered With Licensed Rabies Vaccines (RabiesMab)

Human Rabies

United States
Duke University

Active, not recruiting

A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center) (ADOPT PGx)

Depression | Chronic Pain | Acute Pain

United States
Eisai Inc.

Completed

Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole, Itraconazole, or Rifampin in Healthy Subjects

Healthy Participants

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Drug Interaction of PA-824, an Investigational Tuberculosis Medication, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampin

Tuberculosis

United States
Annemieke Geluk
The Leprosy Mission Bangladesh

Recruiting

Novel Interventions and Diagnostic Tests for Leprosy (INDIGO#2)

Leprosy

Bangladesh
Takeda

Completed

A Study of Soticlestat and Rifampin in Healthy Adults

Healthy Volunteers

United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Drug-drug Interaction Study of SHR2150 on Healthy Chinese Volunteers

Human Immunodeficiency Virus Infection

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Drug-Drug Interaction of Pyrotinib With a Moderate CYP3A Inducer

Healthy Subjects, Drug-drug Interaction, Pyrotinib

China
Johns Hopkins University

Withdrawn

Epidemiology and Treatment of Small-colony Variant Staphylococcus Aureus in Cystic Fibrosis

Cystic Fibrosis | MRSA

United States
Peking Union Medical College Hospital
National Key Technologies R&D Program for the 13th Five-year Plan; National... and other collaborators

Completed

Efavirenz 400mg in Treatment-naïve Chinese HIV-infected Patients

HIV-1-infection

China
Bristol-Myers Squibb

Completed

An Investigational Study to Evaluate the Effect of Rifampin on the Singe Dose of Experimental Medication BMS-986224 in Healthy Participants

Healthy Participants

United States
University of Oulu
Oulu University Hospital

Completed

The Effects of PXR Activation on Hepatic Fat Content

Non-alcoholic Fatty Liver Disease

Finland
Hoffmann-La Roche

Completed

A Study of the Effect of Multiple Doses of Rifampin on the Single Dose Pharmacokinetics of RO5424802

Healthy Volunteer

United States
Nivalis Therapeutics, Inc.
Davita Clinical Research

Completed

A Drug-Drug Interaction Study of N91115 +/- Rifampin in Healthy Adult Subjects

Drug Interaction Potentiation

United States
Bristol-Myers Squibb
Truven health

Completed

Risk of CV Events With EFV vs. EFV-free Regimens

HIV/AIDS
Kirby Institute
Imperial College London

Completed

The Efavirenz (EFV) Central Nervous System Exposure Sub-study of Encore1 (ENCORE1-CNS)

HIV Infection

Thailand, Germany, United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Assess the Effect of Rifampin on the Pharmacokinetics of PCI-32765 in Healthy Participants

Healthy Participants

United States
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Safety and Pharmacokinetics of Single and Multiple Dose Rifampin in Infants

Infection

United States
Bamrasnaradura Infectious Diseases Institute
Thai Red Cross AIDS Research Centre; Clinical Research Collaborative Network

Completed

Effectiveness of Efavirenz-based Regimen in HIV-1-infected Patients With Nevirapine Hypersensitivity

Treatment Failure, HIV or AIDS | CD4 Cell Counts

Thailand
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Determine the Impact of Multiple Doses of Rifampin on Single-dose Pharmacokinetics of HCV-796

Healthy

Search clinical trials for: Cytochrome p 450 cyp2c19

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