Search clinical trials for: Cytomegalovirus reactivation in stem cell transplant

Total 460543 results

Siriraj Hospital

Not yet recruiting

The Comparison the CMV Infection and Reactivation After Allogeneic Hematopoietic Stem Cell Transplantation Between Standard Regimen, Methotrexate Plus Cyclosporin A, and Post-transplant Cyclophosphamide-based Regimen (CMV)

CMV Infection or Reactivation After Allogenic HSCT
Sumithira Vasu

Recruiting

Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT

Cytomegalovirus | Adenovirus | Donor | Allogeneic Hematopoietic Stem Cell Transplantation Recipient | Solid Organ Transplantation Recipient

United States
Children's Hospital Medical Center, Cincinnati
Hoxworth Blood Center

Recruiting

Donor-Derived Viral Specific T-cells (VSTs) (VSTs)

Allogeneic Stem Cell Transplant | Viral Infection | Viral Reactivation

United States
Melbourne Health
Peter MacCallum Cancer Centre, Australia; Western Sydney Local Health District and other collaborators

Enrolling by invitation

Cytomegalovirus (CMV) Reactivation in Allogeneic HSCT Recipient (CReSCT)

Cytomegalovirus Infections | Immune Suppression | Haematological Malignancy | Organ or Tissue Transplant; Complications

Australia
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

A Cytomegalovirus-Directed Vaccine (CMV-alphaDC1) for Preventing Cytomegalovirus Infection or Reactivation in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Hematopoietic and Lymphoid System Neoplasm | Cytomegaloviral Infection

United States
University Hospital, Ghent

Completed

CMV Specific T Cell Therapy After Allogeneic Stem Cell Transplantation.

Hematological Malignancies | CMV Infection

Belgium
M.D. Anderson Cancer Center
Miltenyi Biotec B.V. & Co. KG

Completed

Autologous Cytomegalovirus (CMV)-Specific Cytotoxic T Cells for Cytomegalovirus (CMV) Reactivation

Lymphoma | Leukemia

United States
Oxford Immunotec

Completed

Observational Trial to Evaluate Hematopoietic Stem Cell Transplantation CMV Reactivation (REACT)

Infection

United States, Canada, Sweden
Maimónides Biomedical Research Institute of Córdoba
QIAGEN Gaithersburg, Inc

Unknown

Impact of the Lack of CMV-Specific CD8+ T Cell Response in CMV-Seropositive Donors in CMV Reactivation After Hematopoietic Stem Cells Transplant in CMV-Seropositive Recipients (CYTHEMAT)

Cytomegalovirus Infection | HSCT

Spain
Imperial College London

Withdrawn

Autologous Cytomegalovirus (CMV) Specific CD8+ T Cells as Treatment for CMV Reactivation

Allogeneic Stem Cell Transplantation | CMV Reactivation | Autologous CMV Specific CD8+ T Cells

United Kingdom
Hadassah Medical Organization

Completed

Valganciclovir in Prevention of Cytomegalovirus (CMV) Reactivation Following Allogeneic-Stem Cell Transplantation (SCT)

Cytomegalovirus | Bone Marrow Transplantation

Israel
Baylor College of Medicine
National Heart, Lung, and Blood Institute (NHLBI); The Methodist Hospital Research... and other collaborators

Completed

Cytotoxic T-Lymphocytes for the Prophylaxis of Cytomegalovirus After Allogeneic Stem Cell Transplant (VICTA)

Cytomegalovirus Infections

United States
Foundation IRCCS San Matteo Hospital
Ministero della Salute, Italy

Recruiting

HCMV Breakthrough Infections During Letermovir Prophylaxis (CMVbreak)

Cytomegalovirus Infections | Hematopoietic Stem Cell Transplantation | Cytomegalovirus Viremia

Italy
Peking University People's Hospital

Not yet recruiting

Multivirus-specific T Cells in the Treatment of Refractory CMV and/or EBV Infection After Allo-HSCT

Stem Cell Transplant | CMV Infection | EBV Infection
The First Affiliated Hospital of Soochow University

Recruiting

Letermovir for the Prevention of CMV Infection in HSCT Recipients Based on the Outcome of mNGS

Hematopoietic Stem Cell Transplantation | CMV Infection

China
The First Affiliated Hospital of Soochow University

Recruiting

Letermovir Prophylaxis for CMV Infection in Haplo-HSCT Recipients: Single-center Data in China

Hematopoietic Stem Cell Transplantation | CMV Infection

China
Children's Oncology Group

Recruiting

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Xiao-Jun Huang

Recruiting

CMV-TCR-T Cells for Refractory CMV Infection After HSCT

Allogeneic Hematopoietic Stem Cell Transplantation | CMV Infection

China
Prof. Tobias Feuchtinger
European Commission; Simbec-Orion Group Ltd, Merthyr Tydfil, UK; Miltenyi Biotec... and other collaborators

Recruiting

Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections (TRACE)

CMV Infection | EBV Infection | Stem Cell Transplant Complications | AdV Infection

Belgium, Spain, France, Germany, Italy, Netherlands
University Hospital, Limoges

Recruiting

AntiCMV molécules Monitoring in Real-life in Stem Cell Recipients (NAViRe)

Cytomegalovirus Infections | Hematopoietic Stem Cell Transplantation | Antivirals | Antiviral Drug Resistance

France
Instituto de Investigación Marqués de Valdecilla

Recruiting

Prophylaxis of Cytomegalovirus Infection With Adoptive Cell Inmunotherapy (INMUNOCELL)

CMV

Spain
University of Wisconsin, Madison
University of Wisconsin Carbone Cancer Center (UWCCC)

Recruiting

Treatment of Cytomegalovirus (CMV) Infections With Viral-Specific T Cells

Cytomegalovirus Infections | Opportunistic Infections | CMV Infection | CMV Viremia

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Treating Pediatric Patients With Positive Cytomegalovirus Undergoing Donor Stem Cell Transplant

Hematopoietic Cell Transplant Recipient | Cytomegaloviral Infection

United States
Mari Dallas

Recruiting

T Cell Therapy of Opportunistic Cytomegalovirus Infection

Cytomegalovirus Infections | Opportunistic Infections | Hematopoietic Stem Cell Transplant

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Trial of Third Party Donor Derived CMVpp65 Specific T-cells for The Treatment of CMV Infection or Persistent CMV Viremia After Allogeneic Hematopoietic Stem Cell Transplantation

CMV Infection | Persistent CMV Viremia

United States
University Hospital, Basel, Switzerland

Recruiting

A Study to Assess Safety and Feasibility of Direct Infusions of Donor-derived Virus-specific T-cells in Recipients of Hematopoietic Stem Cell Transplantation With Post-transplant Viral Infections Using the Cytokine Capture System® (CCS)

Cytomegalovirus Infections | EBV | Adenovirus Infection | Cytokine Capture System | Allogenic Disease

Switzerland
Ohio State University Comprehensive Cancer Center
Merck Sharp & Dohme LLC

Active, not recruiting

Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

Sezary Syndrome | Chronic Lymphocytic Leukemia | Peripheral T-Cell Lymphoma | Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | T-Cell Prolymphocytic Leukemia | B-Cell Prolymphocytic Leukemia

United States
Merck Sharp & Dohme LLC

Completed

A Study of Letermovir (MK-8228) to Evaluate Efficacy and Safety for Prevention of CMV Infection in Chinese Hematopoietic Stem Cell Transplant Recipients (MK-8228-045)

Cytomegalovirus Infection

China
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditions

United States
Takeda

Completed

A Study on Cytomegalovirus (CMV) Infection Outcomes Among Hematopoietic Stem Cell Transplant (HSCT) Participants in Europe and Canada

Cytomegalovirus (CMV)

Belgium, Israel, Canada, Serbia, Austria, Greece, Poland
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Vaccine Therapy in Reducing the Frequency of Cytomegalovirus Events in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Myelofibrosis | Chronic Lymphocytic Leukemia | Adult Acute Myeloid Leukemia in Remission | Myelodysplastic Syndrome | Adult Acute Lymphoblastic Leukemia in Remission | Myeloproliferative Neoplasm | Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Hodgkin Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Myelodysplastic/Myeloproliferative Neoplasm | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Cytomegalovirus... and other conditions

United States
Merck Sharp & Dohme LLC

Completed

Letermovir Treatment in Pediatric Participants Following Allogeneic Haematopoietic Stem Cell Transplantation (HSCT) (MK-8228-030)

Cytomegalovirus (CMV) Infection

United States, Australia, Colombia, France, Germany, Israel, Japan, Mexico, Poland, Spain, Turkey
Peking University People's Hospital

Enrolling by invitation

Immune Reconstitution to CMV After HSCT: Impact of Clinical Factors and Therapy Strategies

Hematopoietic Stem Cell Transplantation | CMV Infection

China
Michael Pulsipher, MD

Active, not recruiting

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation (ACES)

Cytomegalovirus Infections | EBV Infection | Adenovirus Infection

United States
New York Medical College
Merck Sharp & Dohme LLC

Completed

Cytomegalovirus (CMV) Viremia and Disease Occurrence in Pediatric Allogeneic Stem Cell Transplantation Recipients

Cytomegalovirus Infections

United States
Astellas Pharma Inc
Vical

Completed

Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)

Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
Shanghai General Hospital, Shanghai Jiao Tong University...
Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China

Completed

CMV-CTL for the Treatment of CMV Infection After HSCT

Cytomegalovirus Infections | Hematological Disease

China
Shire
Takeda Development Center Americas, Inc.

Completed

A Study of Maribavir Compared to Valganciclovir to Treat Cytomegalovirus Infections in People Who Have Received Stem Cell Transplants

Cytomegalovirus (CMV)

United States, China, Spain, Belgium, Australia, Germany, Italy, Canada, France, Croatia, Singapore, United Kingdom, New Zealand, Korea, Republic of, Russian Federation, Poland, Austria, Greece, Switzerland, Czechia, Hungary, Israel, Turk...
Dong-Gun Lee

Enrolling by invitation

Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation

HBV | Hematopoietic Stem Cell Transplantation | Hepatitis B Reactivation | Antiviral Drug

Korea, Republic of
Gruppo Italiano Trapianto di Midollo Osseo
Azienda Policlinico Umberto I

Completed

Prospective Survey of CMV, Herpesviruses Infections and Diseases in Allo-HSCT (CYTOALLOSURVEY)

Hematologic Diseases | Stem Cell Transplant Complications | Cytomegalovirus Viremia | Herpesvirus Infection

Italy
Merck Sharp & Dohme LLC

Completed

Extension of Letermovir (LET) From Day 100 to Day 200 Post-transplant for the Prevention of Cytomegalovirus (CMV) Infection in Hematopoietic Stem Cell Transplant (HSCT) Participants (MK-8228-040)

Cytomegalovirus Infection

United States, France, Germany, Italy, Japan, United Kingdom
Fundación Pública Andaluza para la Investigación...
Merck Sharp & Dohme LLC

Completed

Cytomegalovirus Infection After HSCT and PT-CY as GVHD Prophylaxis >> GVHD PROPHYLAXIS ERA (CY-CMV-2020)

CMV Infection

Spain
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness of the Hepatitis B Vaccine Post-Hematopoietic Stem Cell Transplant

Hepatitis B

United States
Chimerix

Completed

Study of CMX001 to Prevent/Control Cytomegalovirus Infection in R+ Hematopoietic Stem Cell Transplant Recipients

Cytomegalovirus Infection

United States
Shire

Completed

Prophylactic Use of Maribavir for the Prevention of Cytomegalovirus (CMV) Disease in Stem Cell Transplant Recipients

Cytomegalovirus Infections

United States, Canada, United Kingdom, Germany, France, Belgium, Italy, Spain, Sweden
Shire

Completed

Maribavir for Prevention of CMV After Stem Cell Transplants

Cytomegalovirus Infection

United States
Memorial Sloan Kettering Cancer Center
Atara Biotherapeutics

Completed

Primary Transplant Donor Derived CMVpp65 Specific T-cells for The Treatment of CMV Infection or Persistent CMV Viremia After Allogeneic Hematopoietic Stem Cell Transplantation

Cytomegalovirus

United States
University of Erlangen-Nürnberg Medical School
German Research Foundation; Charite University, Berlin, Germany; Ludwig-Maximilians... and other collaborators

Completed

Preventative/Preemptive Adoptive Transfer of Peptide Stimulated CMV/EBV Specific T-cells in Patients After Allogeneic Stem Cell Transplantation

Patients Undergoing Allogeneic Stem Cell Transplantation

Germany
Memorial Sloan Kettering Cancer Center

Completed

Trial of Donor T Cells Sensitized With Pentadecapeptides of the CMV-PP65 Protein for the Treatment of Cytomegalovirus (CMV) Infections Following Allogeneic Hematopoietic Stem Cell Transplants

Cytomegalovirus Infections

United States

Search clinical trials for: Cytomegalovirus reactivation in stem cell transplant

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