Search clinical trials for: DNA biomarker

Total 16882 results

Helse Nord-Trøndelag HF
Norwegian University of Science and Technology

Not yet recruiting

Circulating Tumor DNA in Patients Summoned for Colonoscopy; - a Liquid Biopsy for Detection, Characterization, Individualized Treatment and Follow-up of Colorectal Cancer (CoLiQ)

Colorectal Cancer | Colorectal Adenoma
H. Lee Moffitt Cancer Center and Research Institute
National Institutes of Health (NIH)

Recruiting

Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC) (BASH OPC)

Oropharyngeal Cancer | HPV-Related Carcinoma

United States
Peking University Third Hospital
Beijing Tsinghua Changgeng Hospital

Recruiting

Evaluation of diagnostiC Capacity of eccDNAs as Biomarkers in Indetermined biLiary Stricture(ECCBILE) (ECCBILE)

Bile Duct Cancer | Pancreas Cancer | Biliary Stricture

China
WomenX Biotech Limited
Hong Kong Science and Technology Parks Corporation

Recruiting

Non-invasive Biomarker Discovery for Pre-cervical or/and Cervical Cancer-HPV DNA and Other Biomarkers in Urine

Cervical Cancer

Hong Kong
Universitaire Ziekenhuizen KU Leuven

Recruiting

Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease (NICO)

Neurodevelopmental Disorders | Biomarkers | Congenital Heart Disease | Electroencephalography | Near-Infrared Spectroscopy

Belgium
University of Manchester
Cancer Research UK

Recruiting

Developing Circulating and Imaging Biomarkers Towards Personalised Radiotherapy in Lung Cancer (VIGILANCE)

Lung Cancer Stage III

United Kingdom
Helsinki University Central Hospital

Recruiting

Biomarkers for Diagnosis, Prognosis, and Targeted Therapy After Heart Transplantation (EMBIO)

Heart Transplant Rejection

Finland
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Detection of Plasma DNA of Renal Origin in Kidney Transplant Patients (DART-REIN)

Acute Kidney Injury | Renal Transplantation

France
Liverpool University Hospitals NHS Foundation Trust
Kidney Research United Kingdom

Not yet recruiting

Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients (HLA-AB)

Frailty | Kidney Transplant Rejection | Renal Transplant | Diagnosis | Kidney Transplant; Complications | Kidney Transplant | Renal Transplant Failure | Transplant Dysfunction

United Kingdom
Fudan University
Guangzhou Burning Rock Dx Co., Ltd.

Recruiting

PERformance of Multi-Cancer Early-detectIon Based on Various Biomarkers in fEmale Cancers, PERCEIVE-II

Gynecologic Cancer

China
RenJi Hospital

Not yet recruiting

Multiomics Study of Fibrosis Factors After Liver Transplantation and Exploration of Fibrosis Methylation Biomarkers

Liver Fibrosis

China
Regina Elena Cancer Institute
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Weizmann Institute... and other collaborators

Recruiting

Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus

Liquid Biopsy | Squamous Cell Carcinoma of the Oropharynx | Lymph Node Metastasis | Carcinomas of Unknown Primary Site | High-risk Human Papillomavirus Infection | Occult Tumor of the Head and Neck Area

Italy
Fujian Cancer Hospital

Not yet recruiting

A Study to Evaluate Lenvatinib Plus Tislelizumab for Locally Advanced Unresectable or Metastatic Hepatocellular Carcinoma With Hepatitis B Virus Infection and Biomarker Analyses

Hepatocellular Carcinoma
Azienda Ospedaliera Universitaria Integrata Verona

Recruiting

Circulating Tumor DNA as Surgical Biomarker in Patients With PancrEatic Adenocarcinoma for Statement of Resectability (CASPER)

PDAC - Pancreatic Ductal Adenocarcinoma

Italy
Centro di Riferimento Oncologico - Aviano

Recruiting

Monitoring luminAl Breast Cancer Through the Evaluation of Mutational and epiGeNEtic alteraTIons of Circulating ESR1 DNA (MAGNETIC1)

Breast Neoplasms | Breast Diseases | Antineoplastic Agents | Aromatase Inhibitors | Neoplasms, Breast | Hormone Receptor Positive Breast Carcinoma | ESR1 Gene Mutation

Italy
Centre Hospitalier Universitaire, Amiens

Recruiting

Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity (EPSACO)

Biomarkers | Epigenetics | Oral Squamous Cell Carcinoma | DNA Methylation | Saliva | Maxillo-facial Surgery

France
University of Aarhus
Aarhus University Hospital

Recruiting

Improved Diagnosis of Ovarian Cancer by Use of Circulating Tumor DNA as a Biomarker

Ovarian Cysts | Ovarian Neoplasms | Ovary Cancer

Denmark
Hospital do Coracao
University of Sao Paulo

Not yet recruiting

Adjuvant Chemotherapy in cfHPV-DNA Plasma Positive Patients: A Biomarker In Locally Advanced Cervical Cancer (AddChemo)

Cervical Cancer | Cervix Cancer | Cervix Neoplasm

Brazil
National Taiwan University Hospital

Not yet recruiting

A Novel Biomarker for Response and Prognosis of HBV-related Hepatocellular Carcinoma

Hepatocellular Carcinoma | Radiotherapy | Biomarker | Hepatitis b Virus
Elicio Therapeutics

Recruiting

A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors (AMPLIFY-7P)

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma | KRAS G12D | KRAS G12R | NRAS G12D | NRAS G12R | KRAS G12V | KRAS G12C | KRAS G12A | KRAS G12S | KRAS G13D | NRAS G12V | NRAS G12C | NRAS G12S

United States
University of Aarhus
Randers Regional Hospital

Recruiting

Screening Triage and Risk Stratification (I-share)

Cervix Cancer | Postmenopausal Women | HPV Testing

Denmark
Sohag University

Recruiting

Mitochondrial DNA Copy Number and Leukocyte Telomere Length as Biomarkers in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Egypt
Royal Marsden NHS Foundation Trust

Recruiting

Exploratory Study of Early Biomarkers Allowing Dynamic Assessment of Response to Treatment in Cancers of the Head and Neck (DART)

Head and Neck Cancer

United Kingdom
Seoul National University Hospital
DXOME CO., LTD.

Recruiting

Association Between Cell-free Nucleic Acid in Blood, Urine and Microbiome in Stool With Pancreatobiliary Cancer

Pancreatic Cancer | Cholangiocarcinoma | Gallbladder Cancer

Korea, Republic of
The First Affiliated Hospital with Nanjing Medical...
Innovent Biologics (Suzhou) Co. Ltd.; Nanjing Geneseeq Technology Inc.

Not yet recruiting

A Biomarker Study for Predicting the Efficacy of Neoadjuvant Sintilimab Plus SOX for Gastric Adenocarcinoma.

Gastric Cancer
UNICANCER

Recruiting

SURVEILLE-HPV: Evaluation of HPV16 Circulating DNA as Biomarker to Detect the Recurrence, in Order to Improve Post Therapeutic Surveillance of HPV16-driven Oropharyngeal Cancers (SURVEILLE-HPV)

Oropharynx Squamous Cell Carcinoma

France
University Hospital, Montpellier

Recruiting

Screening for Prognostic Biomarkers of Severe Bell's Palsy in Adults (BIOFIPS)

Bell Palsy

France
University of Mississippi Medical Center

Not yet recruiting

Clinical, Translational and Biomarker-Based Female Genital HPV Induced Dysplasia and Cancer Screening Study Using Cf-HPV-DNA Blood Tests (TTMV HPV DNA)

Cervical Dysplasia, Uterine | Vaginal Dysplasia | Vulvar Dysplasia
National Cancer Centre, Singapore

Recruiting

Treatment Individualisation by EBV Stratification in Nasopharyngeal Carcinoma: a Prospective Observational Study

Nasopharyngeal Carcinoma

Singapore
Xijing Hospital

Recruiting

Biomarker Analysis of Tislelizumab Combined With Chemotherapy for Perioperative Treatment of G/GEJ Adenocarcinoma

PD-1 | Locally Advanced Gastric Adenocarcinoma

China
Changhai Hospital
Guangzhou Burning Rock Bioengineering Ltd.

Recruiting

iDentification and vAlidation Model of Liquid biopsY Based cfDNA Methylation and pRotEin biomArKers for Pancreatic Cancer (DAYBREAK Study)

Cancer

China
Fuzhou General Hospital

Not yet recruiting

ctDNA as a Biomarker for Treatment in Advanced NSCLC

Non-small Cell Lung Cancer

China
University of Minnesota

Recruiting

Blood Biomarkers in Pediatric Kidney Transplant Recipients (Omnigraf)

Rejection of Kidney Allograft

United States
Wonju Severance Christian Hospital
National Research Foundation of Korea

Recruiting

The Effectiveness of Urine mtDNA and Beta 2-MG to Predict Acute Kidney Injury for Critically Ill Surgical Patients

Critical Illness | Acute Kidney Injury | Surgery-Complications

Korea, Republic of
Lille Catholic University
Auckland University

Recruiting

Imagery as Biomarker of Gout (TIGER)

Hyperuricemia

France
Heath Skinner

Recruiting

Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

Oropharynx Cancer

United States
Istituto Nazionale di Ricovero e Cura per Anziani

Not yet recruiting

Analysis of the Prognostic Role of Epigenetic Biomarkers in Relation to the Motor Decline in Parkinson's Disease (BioGenPark)

Parkinson Disease
Institut Claudius Regaud
Artios Pharma Ltd

Recruiting

Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer. (REPARP)

Breast Cancer

France
University Hospital, Rouen

Not yet recruiting

Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Monitoring Circulating Tumor DNA (REMNANT)

Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
Guangzhou Burning Rock Bioengineering Ltd.

Recruiting

Detection of Peritoneal Metastasis of Gastric Cancer by Liquid Biopsy in Peripheral Blood: A Prospective Study

Cancer

China
Creative Biosciences (Guangzhou) Co., Ltd.
Guangzhou Xiangkang Medical Research Co., Ltd.

Recruiting

A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China

Bladder Cancer | Urothelial Carcinoma | Urocystitis | Urinary Bladder Stone

China
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Molecular Markers in Cancers and Precancers (MOCA) (MOCA)

Healthy | Cancer | Precancerous Lesion
Genomictree, Inc.
Samsung Medical Center; Pusan National University Hospital; Asan Medical Center; Seoul National University Hospital and other collaborators

Recruiting

A Stool DNA-based SDC2 Methylation Test for the Early Detection of Colorectal Cancer

Colorectal Cancer | Advanced Colorectal Neoplasm | Advanced Adenomas | Non-neoplastic Polyps | Non-advanced Adenomas

Korea, Republic of
Pusan National University Yangsan Hospital

Recruiting

Cell-free DNA Quantification for Predictive Marker of Palliative Chemotherapy

Biomarkers | Fluorescence | Cell-Free Nucleic Acids | Palliative Chemotherapy

Korea, Republic of
Shanghai Zhongshan Hospital
Guangzhou Burning Rock Bioengineering Ltd.

Recruiting

AssesSment of Early-deteCtion basEd oN liquiD Biopsy in GASTRIC Cancer, ASCEND-Gastric (ASCEND-Gastric)

Cancer

China
Qianfoshan Hospital

Recruiting

Novel Biomarkers of Hypoxia and Metabolism in Clear Cell Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma

China
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

DNA Sequencing in Clinical Practice, Mayo Clinic Health Tapestry Study

Genetic Disorder

United States
Hospices Civils de Lyon

Recruiting

CIRculating CANcer MAster-Protocol (CIRCAN MAP)

Adult With Solid Cancer

France
Centre hospitalier de l'Université de Montréal...
Exactis Innovation; Chaire Roger Des Groseillers d'oncologie chirurgicale HBP... and other collaborators

Recruiting

Early Detection of Treatment Failure in Metastatic Colorectal Cancer Patients (eDetect-mCRC)

Colorectal Cancer Metastatic

Canada
Universidad de Antioquia
Laboratorio departamental de salud publica de Antioquia; Sistema general de...

Recruiting

Correlation Between Cycle Threshold (Ct) Values in COVID-19, Health Status and Laboratory Biomarkers in the Population of Medellin- Colombia Evaluated in a Specialized Laboratory.

Covid19

Colombia

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