Search clinical trials for: DNA Damage Response Inhibitor
Total 87795 results
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EMD Serono Research & Development Institute, Inc.Merck KGaA, Darmstadt, GermanyRecruitingMetastatic or Locally Advanced Unresectable Solid TumorsUnited States, Canada, Spain
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The Netherlands Cancer InstituteLeiden University Medical Center; University Medical Center NijmegenRecruitingSoft Tissue Sarcoma AdultNetherlands
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Marc Dall'Era, MDNational Cancer Institute (NCI); Janssen, LPRecruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Prostate Carcinoma | RAD51C Gene Mutation | BRIP1 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CDK12 Gene Mutation | CHEK1 Gene Mutation | DNA Damage Response Gene Mutation | DNA Repair Gene Mutation | FANCA Gene Mutation and other conditionsUnited States
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Institute of Cancer Research, United KingdomAstraZenecaRecruitingBreast NeoplasmUnited Kingdom
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University Health Network, TorontoAstraZenecaActive, not recruitingPancreatic Adenocarcinoma | Leiomyosarcoma | Mismatch Repair Proficient Colorectal CancerCanada
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Actuate Therapeutics Inc.Active, not recruitingSarcoma | Cancer | Breast Neoplasms | Neoplasm Metastasis | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Bone Cancer | Malignant Glioma | Bone Metastases | Pancreas Cancer | Renal Cancer | Refractory Non-Hodgkin Lymphoma | Bone Neoplasm | Neoplasm, Breast | Refractory Cancer | Refractory Neoplasm | Resistant... and other conditionsUnited States, Belgium, Canada, Spain, France, Netherlands, Portugal
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National Cancer Institute (NCI)Active, not recruitingUterine Cervical Neoplasms | Small Cell Lung Carcinoma | Ovarian Neoplasms | Carcinoma, Neuroendocrine | Extrapulmonary Small Cell Cancer | Carcinoma, Non-Small -Cell LungUnited States
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PfizerAstellas Pharma IncActive, not recruitingProstate CancerUnited States, Finland, China, France, Spain, Hungary, United Kingdom, Korea, Republic of, Canada, Czechia, Taiwan, Belgium, Australia, Argentina, Japan, Germany, India, Turkey, Slovakia, Russian Federation, Bulgaria, Italy, Ukraine, ... and more
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Matthew GalskyIcahn School of Medicine at Mount Sinai; AstraZenecaCompletedMetastatic Urothelial CancerUnited States
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University of FloridaGlaxoSmithKlineCompletedRenal Cell Carcinoma | Mesothelioma | Cholangiocarcinoma | Uveal MelanomaUnited States
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Korean Cancer Study GroupUnknownMetastatic Solid Tumor | DDR Gene MutationKorea, Republic of
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Attikon HospitalUnknownDNA Damage | HNSCC | DNA Double Strand BreakGreece
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Canadian Cancer Trials GroupCanadian Institutes of Health Research (CIHR)Not yet recruitingMetastatic Prostate Cancer | Metastatic Castration-resistant Prostate Cancer
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University Hospital, GrenobleNational Agency for Research on AIDS and Viral Hepatitis (ANRS)Not yet recruitingLiver Transplantation | Kidney Transplantation | HBVFrance
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Virginia G. KaklamaniNot yet recruitingTriple Negative Breast Cancer | DNA Damage Repair DeficiencyUnited States
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Gene SolutionsRecruitingNon Small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Stage IIIC Non-Small Cell Lung Cancer | Tyrosine Kinase InhibitorsVietnam
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Spanish Cooperative Group for the Treatment of...AstraZenecaRecruitingMetastatic Pancreatic CancerSpain
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Seoul National University HospitalNot yet recruitingAdvanced Breast CancerKorea, Republic of
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University of UtahRepare TherapeuticsRecruitingChronic Lymphocytic LeukemiaUnited States
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H. Lee Moffitt Cancer Center and Research InstituteRecruitingMerkel Cell Carcinoma | Cutaneous Melanoma | Cutaneous Squamous Cell CarcinomaUnited States
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Asan Medical CenterRecruitingBiliary Tract Cancer | DNA Damage Repair DeficiencyKorea, Republic of
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The University of Hong KongRecruitingRecurrent Glioblastoma | Recurrent Glioma | Poly ADP Ribose Polymerase (PARP) Inhibitor | PTEN Gene Inactivation | IDH MutationHong Kong
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New Discovery LLCBeijing Ditan HospitalRecruitingHepatitis B, ChronicChina
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NHS LothianRecruitingProstate Cancer | DNA Damage | Volatile Organic Compounds | Radiotherapy Side EffectsUnited Kingdom
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Laval UniversityCanadian Institutes of Health Research (CIHR); AstraZenecaRecruiting
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National Cancer Institute (NCI)RecruitingSmall Cell Lung Cancer | Lung Cancer | Carcinoma, Small CellUnited States
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New Discovery LLCRecruitingViremia | Hepatitis B Infection | Chronic Infection | Birth Defect | Congenital MalformationChina
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National Institute of Environmental Health Sciences...CompletedInflammation | Cancer | Cardiomyopathy | HIV-1 SeropositiveUnited States
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National Cancer Institute (NCI)Active, not recruitingMalignant Glioma | Recurrent Childhood Ependymoma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent... and other conditionsUnited States, Puerto Rico
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M.D. Anderson Cancer CenterMerck Sharp & Dohme LLC; AstraZenecaActive, not recruitingProstate Carcinoma | Prostate Cancer AggressivenessUnited States
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National Cancer Institute (NCI)CompletedNSCLC | Solid Tumors | Lymphomas | Granulosa Cell Ovarian Cancer | Metastatic Colon CarcinomaUnited States
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National Cancer Institute (NCI)CompletedNeoplasms | LymphomaUnited States
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Instituto de Seguridad y Servicios Sociales de...CompletedDNA Damage | Nutrition Therapy | HBOC SyndromeMexico
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AstraZenecaActive, not recruitingMetastatic Triple Negative Breast CancerUnited States, Belgium, Italy, Spain, United Kingdom, Canada, Czechia, Poland, France, Korea, Republic of, Germany, Taiwan, Portugal, Netherlands, Ireland
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Edoardo MelilliWithdrawnKidney Transplantation | Cytomegalovirus InfectionsSpain
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AstraZenecaActive, not recruitingAdvanced Solid TumoursUnited States, France, Spain
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University of ArizonaTerminatedBreast CancerUnited States
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New York Medical CollegeMerck Sharp & Dohme LLCCompletedCytomegalovirus InfectionsUnited States
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National Cancer Institute (NCI)CompletedLymphoma | Solid TumorsUnited States
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University of California, San FranciscoMerck Sharp & Dohme LLCCompletedMetastatic Prostate Cancer | Castration Resistant Prostatic CancerUnited States
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Huahui HealthActive, not recruiting
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University of ChicagoNational Cancer Institute (NCI)Active, not recruitingHuman Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the OropharynxUnited States
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ppharmaand GmbHBristol-Myers Squibb; Gynecologic Oncology Group; European Network of Gynaecological... and other collaboratorsActive, not recruitingFallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal | Newly Diagnosed | FIGO Stage III-IV | Partial Response | Complete ResponseUnited States, United Kingdom, Korea, Republic of, Russian Federation, Canada, Denmark, Taiwan, New Zealand, Ireland, Japan, Spain, Australia, Israel, Italy, Greece, Sweden, Czechia, Finland, Poland, Belgium, Germany, Romania, Singa... and more
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Daniel BenjaminEunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaboratorsCompletedHeart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditionsUnited States, Canada, United Kingdom, Israel, Singapore
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National Heart, Lung, and Blood Institute (NHLBI)CompletedChronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Safety and Tolerability | Compare SHINGRIX Vaccine Response RatesUnited States
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Atara BiotherapeuticsNo longer availableLymphoproliferative Disorders | Stem Cell Transplant Complications | Epstein-Barr Virus (EBV) Infections | EBV+ Associated Lymphoma | EBV+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD) | Epstein-Barr Viremia | Lymphoma, AIDS-related | Epstein-Barr Virus-associated Lymphoproliferative... and other conditions
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Assembly BiosciencesTerminatedChronic Hepatitis BUnited States, Canada, Hong Kong, New Zealand, United Kingdom
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National Cancer Institute (NCI)TerminatedBreast Cancer | Ovarian Cancer | Prostate CancerUnited States
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Mylan (Taiwan) LtdCompleted
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Calithera Biosciences, IncTerminatedClear Cell Renal Cell Carcinoma | Colorectal Cancer | Solid Tumor | CRC | TNBC - Triple-Negative Breast Cancer | ccRCC | RCCUnited States