Search clinical trials for: Direct Acting Antiviral

Total 18655 results

Applied Science & Performance Institute

Recruiting

The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States

Cognitive Change | Mood Change | Mental Processes

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Improving Response to Immunotherapy in Patients With Advanced Hepatocellular Carcinoma and Chronic Hepatitis C Virus Infection With Direct-Acting Antiviral Therapy

Liver Cancer

United States
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Prophylaxis With Direct-acting Antivirals for Kidney Transplantation From HCV-Infected Donors to Uninfected Recipients (PREVENT-HCV)

HCV

United States
Institut Pasteur
National Institute of Hygiene and Epidemiology, Vietnam; ANRS, Emerging Infectious...

Not yet recruiting

Evaluation of HCV Care and Treatment for HIV-HCV Co-infected Patients in Decentralised Areas in Vietnam (MOVIDA-Hep2)

HIV Infection | Hepatitis C Infection

Vietnam
Medical University of Warsaw

Recruiting

Possible Differences in HCC Course Depending on DAA Treatment

Liver Cirrhosis | Carcinoma, Hepatocellular | Hepatitis C, Chronic | Drug Effect | Hepatitis C Virus Infection, Response to Therapy of | Drug Side Effect

Poland
Tanta University

Not yet recruiting

Treatment of Hepatitis c by Using Direct-acting Antiviral

Hepatitis C
The Task Force for Global Health
Centers for Disease Control and Prevention

Recruiting

The Treatment in Pregnancy for Hepatitis C ("TiP-HepC") Registry (TiP-HepC)

Hepatitis C

United States
Qing XIe
Gilead Sciences; Tigermed Consulting Co., Ltd

Recruiting

Effectiveness and Safety of Direct-Acting Antiviral Agents for the Treatment of Chronic Hepatitis C (C-DIAMOND)

Hepatitis C, Chronic

China
Ain Shams University

Recruiting

PK of SOF/LED in HCV - Infected Adolescents With Haematological Disorders

HCV Infection | Beta Thalassemia Major

Egypt
Jordan Feld
University Health Network, Toronto

Recruiting

Transplantation Using Hepatitis C Positive Donors, A Safety Trial

Hepatitis C | Kidney Transplant Infection | Heart Transplant Infection | Lung Transplant Infection | Kidney Pancreas Infection

Canada
Kirby Institute
National Health and Medical Research Council, Australia

Recruiting

ETHOS ENGAGE: Enhancing Treatment of Hepatitis C in Opioid Substitution Settings (ETHOS II)

Hepatitis C

Australia
University of California, San Diego

Recruiting

Impact of DAA Uptake in Controlling HCV Epidemic and Modeling Interventions for HCV Elimination Among HIV-infected Persons in San Diego

Hepatitis C | Hepatitis C, Chronic | HIV/AIDS

United States
National Institute of Diabetes and Digestive and...

Recruiting

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

Cardiovascular Diseases | Diabetes Mellitus | Hepatitis C, Chronic

United States
Kaohsiung Medical University Chung-Ho Memorial...

Recruiting

Nation-wide Hepatitis C Virus (HCV) Registry in Taiwan

Hepatitis C, Chronic

Taiwan
Catholic University of the Sacred Heart

Recruiting

HIV-DNA Dynamics in HIV Monoinfected or HIV/HCV Coinfected Patients (ViDyMoCo)

HIV

Italy
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); AbbVie

Completed

Glecaprevir/Pibrentasvir Fixed-dose Combination Treatment for Acute Hepatitis C Virus Infection (PURGE-C)

HIV Infection | Hepatitis C Infection

United States, Brazil
Egyptian Liver Hospital

Active, not recruiting

The Study of the Validation of General Evaluation Score (GES) in the Prediction of Hepatocellular Carcinoma Risk Among Patients With Advanced Fibrosis and Cirrhosis Who Achieved Sustained Virological Response for Hepatitis C Virus After Direct Acting Antiviral Drugs

Hepatocellular Carcinoma

Egypt
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Completed

A Phase IIb Study to Evaluate a Long-Acting Intramuscular Regimen for Maintenance of Virologic Suppression (Following Induction With an Oral Regimen of GSK1265744 and Abacavir/Lamivudine) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected, Antiretroviral Therapy-Naive Adult Subjects

HIV Infections | Infection, Human Immunodeficiency Virus

Germany, Spain, France, United States, Canada
Postgraduate Institute of Medical Education and...

Completed

Effects of Direct-acting Antiviral Agents on HCV Cognitive Function, and Depression in HCV Related Cirrhosis: A Prospective Clinical Trial

Depression in Chronic Hepatitis C

India
VA Office of Research and Development
Oregon Health and Science University; Portland VA Medical Center

Completed

HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS Function

Hepatitis C | Alcohol Use Disorder

United States
University of Bari

Completed

Autoantibodies and Direct-acting Antivirals (BIOEPA)

Viral Hepatitis C | Therapy Adverse Effect

Italy
National Institute of Diabetes and Digestive and...

Completed

Hepatitis B Reactivation During Treatment With Direct-Acting Antiviral Agents for Chronic Hepatitis C Infection

Hepatitis B

United States
ANRS, Emerging Infectious Diseases

Completed

DRug Use & Infections in ViEtnam - Hepatitis C (DRIVE-C) (DRIVE-C)

Hepatitis C | Viral Hepatitis C | Drug Use

Vietnam
Massachusetts General Hospital

Completed

QUICKly Eradicate Hepatitis C in Patients Undergoing REnal Transplant With 4 Weeks of Glecaprevir/Pibrentasvir (QUICK-CURE)

Hepatitis C | Kidney Disease, Chronic | Kidney Failure

United States
University of Maryland, Baltimore

Withdrawn

Hepatitis C Positive Donor Into Hepatitis C Negative Recipients

Hepatitis C

United States
Massachusetts General Hospital

Terminated

Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Lung Transplant

Hepatitis C | Respiratory Failure

United States
University of Texas at Austin

Active, not recruiting

Implementing HCV Treatment for High-risk Populations in Austin, Texas

Hepatitis C Virus Infection

United States
Alexandria University

Completed

HCV Related Hepatocellular Carcinoma Recurrence After Directly Acting Antivirals: A Randomized Controlled Trial (RCT)

Hepatocellular Carcinoma | Hepatitis C | Neoplasm Recurrence | Treatment Complication

Egypt
Gilead Sciences

Terminated

A Registry for Adolescent and Pediatric Participants Who Received a Gilead Hepatitis C Virus Direct Acting Antiviral (DAA) in Gilead-Sponsored Chronic Hepatitis C Infection Trials

Hepatitis C Virus Infection

United States, United Kingdom, Australia, Germany, Italy, New Zealand, Belgium, Poland, Russian Federation
Baylor Research Institute

Active, not recruiting

Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients (TROJAN-C)

Heart Failure

United States
University of Washington
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Hepatitis C Pharmacy-based Strategy for Injectors (HepPSI)

Hepatitis C

United States
Massachusetts General Hospital

Withdrawn

HCV + to HCV - Kidney Transplant

Hepatitis C | Kidney Failure
Massachusetts General Hospital

Terminated

DAA Treatment in Donor HCV-positive to Recipient HCV-negative Liver Transplant

End Stage Liver Disease | Hepatitis C

United States
Hospital Mutua de Terrassa

Completed

Evaluation of the Safety and Effectiveness of Direct-acting Antiviral Drugs in the Treatment of Hepatitis C in Patients With Inflammatory Bowel Disease: National Multicenter Study (MIC project)

Inflammatory Bowel Diseases | Hepatitis C Virus Infection

Spain
Valme University Hospital
Hospital General Universitario Elche; Hospital del SAS de Jerez; Clinica Universidad... and other collaborators

Completed

Efficacy and Safety of Therapy Against HCV Based on Direct-acting Antivirals in Real-life Conditions (FPSMON201401)

Chronic Hepatitis C Infection

Spain
Massachusetts General Hospital

Terminated

DAA Treatment in Donor HCV-positive to Recipient HCV-negative Heart Transplant

Hepatitis C | End Stage Heart Disease

United States
Sanjay Gandhi Postgraduate Institute of Medical...
Ram Manohar Lohia Institute of Medical Sciences, Lucknow

Terminated

Re-treatment of HCV Following DAA Failure

Chronic Hepatitis C

India
Kirby Institute

Completed

Direct-acting Antiviral Therapy and Reinfection Among PWID With Chronic HCV in Community-based Settings (SHARP-C)

Hepatitis C, Chronic

Australia
Kirby Institute

Completed

Direct-acting Antiviral Therapy and Reinfection Among People With Chronic Hepatitis C Virus Infection and Recent Injecting Drug Use in the Prison Setting (SHARP-P)

Hepatitis C, Chronic

Australia
Johns Hopkins University

Completed

deLIVER: Direct Acting Antiviral Effects on the Liver (deLIVER)

HIV | Liver Disease | HCV Coinfection

United States
AbbVie

Completed

The Durability of Response and Persistence of Resistance to AbbVie's 2 Direct-acting Antiviral Agent (2D) Therapy in Japanese Subjects

Hepatitis C Virus

Japan
University of Dundee
Burnet Institute; Public Health Wales

Completed

Reaching mEthadone Users Attending Community pHarmacies With HCV (REACH HCV)

Hepatitis C

Australia, United Kingdom
Albert Einstein College of Medicine
Merck Sharp & Dohme LLC; AiCure

Completed

Smartphone Based aDOT Treatment With Fixed-Dose Elbasvir and Grazoprevir in PWIDs

Hepatitis C | Medication Adherence

United States
Kirby Institute

Active, not recruiting

Control and Elimination Within Australia of Hepatitis C From People Living With HIV (CEASE)

Hepatitis C | HIV | HIV-HCV Coinfection

Australia
Hospital de Clinicas de Porto Alegre
Ministry of Health, Brazil; TelessaúdeRS / UFRGS; State Secretary of Health of...

Active, not recruiting

Monitoring of Hepatitis C Treatment Using Telemedicine - a Clinical Trial in Public Health System in Brazil

Chronic Hepatitis C

Brazil
Target PharmaSolutions, Inc.

Completed

Direct Acting Antiviral-Post Authorization Safety Study

Hepatocellular Carcinoma | Hepatitis C

United States, Spain, Germany, France, Italy
Universitätsklinikum Hamburg-Eppendorf
Bristol-Myers Squibb

Completed

Interferon-free Antiviral Treatment of Chronic Hepatitis C Virus Infection Among Opioid-substituted Patients (INFO)

Hepatitis C, Chronic | Opioid-Related Disorders

Germany
Prisma Health-Upstate
Johns Hopkins University; Massachusetts General Hospital; Montefiore Medical... and other collaborators

Completed

Patient-Centered Models of HCV Care for People Who Inject Drugs (HERO)

Hepatitis C | Medication Adherence

United States
Soroka University Medical Center
Loyola University, Harel Dahari, PhD, mathematical modeling support

Completed

Response Guided Treatment With Direct Acting Anti-Viral Medications for Chronic HCV Infection

Hepatitis C

Israel
MassBiologics

Terminated

Open Label Study of the Efficacy and Safety of MBL-HCV1 in Combination With Oral Direct-Acting Antivirals in Patients Undergoing Liver Transplantation for Hepatitis C (MBL-HCV1)

Hepatitis C Infection

United States

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