Search clinical trials for: Efficacy, tolerability, moderate/severe, oxycodone/naloxone

Total 21 results

Assiut University

Not yet recruiting

Efficacy of Ultrasound-assisted Caudal Epidural Pulsed Radiofrequency for Anal Pain in Cancer Patients,

Perineal Pain
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis B

Chronic Hepatitis B

Belgium, Germany, United Kingdom, Philippines
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Study to Assess the Pharmacokinetics of of ASA404 in Adult Cancer Patients With Impaired Hepatic Function

Histologically-proven and Radiologically-confirmed Solid Tumors

Italy, New Zealand
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy

Pain | Constipation

United Kingdom
GlaxoSmithKline

Completed

To Investigate If Single Doses Of GSK618334 Are Safe And To Investigate Blood Levels Of GSK618334

Substance Dependence

United Kingdom
GlaxoSmithKline

Completed

A Study To Investigate The Safety, Tolerability And Blood Levels Of GSK598809

Substance Dependence

Germany
GlaxoSmithKline

Completed

Study To Examine Safety, Tolerability And Pharmacokinetics Of Intravenous Doses And Oral Dose Of GSK233705

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Study To Investigate If Repeat Doses Of GSK598809 Are Safe And Well Tolerated And To Evaluate Blood Levels Of GSK598809

Substance Dependence

United Kingdom
GlaxoSmithKline

Completed

A Study To Assess The Effects Of A Single Dose Of GSK598809 In Modulating Nicotine Reward

Substance Dependence

United States
GlaxoSmithKline

Completed

A Study To Investigate The Effect Of Inhaling A Single Dose Of GW642444M In COPD Patients.

Pulmonary Disease, Chronic Obstructive

Germany
University Hospital Inselspital, Berne

Completed

Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia

Epidural Analgesia | Radical Cystectomy | Postoperative Pain Management | Oral Oxycodone With/Without Naloxone | Return of the Bowel Function

Switzerland
Novartis

Completed

A Study to Compare Ocular Safety and Tolerability of Eye Drops Containing Prednisolone Acetate in Patients With Intraocular Inflammation After Cataract Surgery

Cataract Surgery
AstraZeneca

Completed

To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses AZD8848 in Healthy Subjects

Healthy Subjects | Safety, | Tolerability,

United Kingdom
li nguyen

Unknown

ASIS for Botox in Upper Limb Spasticity (ASISinULS)

Upper Limb Spasticity Unilaterally in Adults With History of Stroke | Increased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors.

United States
ASIS Corporation

Unknown

ASIS for Botox in Chronic Migraine (ASISinCM)

Chronic Migraine More than15 Days Per Month, and Lasting 4 Hours a Day or Longer.

United States
AstraZeneca

Completed

Investigating Safety, Tolerability and Efficacy of AZD5363 in Prostate Cancer. (PYRUS)

Metastatic Castrate-Resistant Prostate Cancer (mCRPC), | Efficacy, | Safety and Tolerability, | Pharmacokinetics, | Pharmacodynamics, | Tumour Response.

United Kingdom, United States
AstraZeneca

Completed

To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ascending Doses of Inhaled AZD7594

Pharmacokinetics | Safety | Pharmacodynamics of AZD7594

United Kingdom
GlaxoSmithKline

Completed

A Three-Part Study Of GSK580416 In Healthy Subjects

Infections, Bacterial | Respiratory Tract Infection

Australia
GlaxoSmithKline

Completed

A Study to Investigate the Effects of GW876008 on Brain Activation During Emotional Processing in Healthy Subjects.

Healthy Subjects

United States
GlaxoSmithKline

Completed

A Study To Investigate The Metabolism Of GW876008 In Smokers Compared To Non-Smokers.

Healthy Subjects

United States
GlaxoSmithKline

Completed

An Investigation To Determine The Potential Interaction Effect Between GW876008 And Midazolam.

Healthy Subjects

United States

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