Search clinical trials for: Exposure chamber

Total 4590 results

BioAegis Therapeutics Inc.

Not yet recruiting

Rhu-pGSN to Mitigate Proinflammatory Responses to Decompression in Healthy SCUBA Divers

Decompression Sickness
University of California, San Diego
LEO Pharma; The Organization of Teratology Information Specialists

Recruiting

Monitoring Pregnancy and Infant Outcomes Following Tralokinumab Exposure During Pregnancy in the US and Canada - PROTECT (PROTECT)

Eczema | Atopic Dermatitis

United States
University of California, San Diego

Recruiting

Researchers at UC San Diego Are Learning About the Benefits of Human Milk and How it Influences Infant and Child Health

COVID-19 Vaccine | Breastfeeding | COVID-19 Infection | Antibiotics | Remdesivir

United States
University of California, San Diego
Janssen Biotech, Inc.; The Organization of Teratology Information Specialists

Recruiting

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

Psoriasis | Pregnancy | Crohn Disease | Psoriatic Arthritis

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing The Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States, Israel
Alyatec
Medicom

Completed

Efficacy of Face Mask in Reducing Respiratory Allergic Symptoms in Birch-allergic Subjects in ALYATEC Exposure Chamber

Allergic Rhinitis | Allergic Asthma

France
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Safety and Efficacy of Low-dose IL-2 in Birch Pollen Allergy (Rhinil-2)

Allergic Rhinoconjunctivitis to Birch Pollen | With a Positive Skin Prick Test to Birch Pollen

France
Alyatec

Completed

Determination of Grass Pollen Allergen Concentration Inducing Rhinoconjunctivitis Symptoms in Subjects Allergic to Grass Pollen in ALYATEC Allergen Exposure Chamber

Allergic Rhinitis Due to Grass Pollen

France
University of California, San Diego
Celgene; The Organization of Teratology Information Specialists

Active, not recruiting

Apremilast Pregnancy Exposure Registry

Psoriasis | Psoriatic Arthritis

United States
Marinomed Biotech AG

Completed

Therapeutic Effect of Tacrosolv in Patients With Allergic Rhinoconjunctivitis

Allergic Rhinitis | Allergic Conjunctivitis

Austria
ALK-Abelló A/S

Terminated

A Research Study in Chinese People With Allergy to House Dust Mites, Using an Environmental Exposure Chamber (QUEST)

Allergic Rhinoconjunctivitis

Austria, China
Chiesi Farmaceutici S.p.A.

Completed

Clinical Pharmacology Study to Evaluate the Total Systemic Exposure and the Lung Availability of CHF 5993 in Healthy Volunteers

COPD

Belgium
Alyatec

Completed

Evaluation of the Nasal and Conjunctival Response in Subjects Allergic to Birch Pollen in the ALYATEC Environmental Exposure Chamber

Allergic Rhinitis | Rhinoconjunctivitis | Allergy to Pollen

France
University of Aarhus
Lund University; University of Copenhagen; Danish Technological Institute; ASP-HOLMBLAD... and other collaborators

Completed

CANDLE - A Study of Acute Health Effects of Exposure to Particles Generated by Candles

Inflammatory Response | Symptoms and Signs

Denmark
Alyatec

Completed

Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Cat Allergic Subjects With Asthma

Allergy | Allergic Asthma | Allergy to Cats

France
Alyatec

Completed

Efficacy of Air Cleaners in Asthmatics Allergic to Cat in ALYATEC Environmental Exposure Chamber

Asthma | Allergy

France
Alyatec

Completed

Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Mite Allergic Subjects With Asthma

Allergy | Allergic Asthma | Allergy to House Dust

France
Allergy Therapeutics

Terminated

Investigation of Efficacy and Safety of Tree MATAMPL,Tree MATA, and Placebo in Patients With Birch-Induced Seasonal Allergic Rhinitis

Type I Hypersensitivity

Canada
Marinomed Biotech AG

Completed

Demonstration of Equivalence and Early Onset of a Novel Anti-allergic Nasal Spray Compared to Marketed Nasal Spray

Allergic Rhinitis | Allergic Conjunctivitis | Hayfever

Austria
Bausch & Lomb Incorporated

Completed

Safety, Pharmacokinetics, and Efficacy of Bepotastine Besilate Nasal Product After Ragweed Pollen Exposure in an Environmental Chamber

Seasonal Allergic Rhinitis

United States
Aldeyra Therapeutics, Inc.

Completed

A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber

Conjunctivitis, Allergic

Canada
Institute of Mountain Emergency Medicine
Medical University Innsbruck; Università degli Studi di Trento; University of... and other collaborators

Completed

Effects of Acute Hypobaric Hypoxia Exposure on Neurocognitive Performance of Pre-hospital Emergency Service Providers

Emergency Medicine | Cognitive Deterioration | Stress Physiology | Resuscitation | Hypobaric Hypoxia

Italy
Dynavax Technologies Corporation

Completed

An Evaluation of the Efficacy and Safety of TOLAMBA™ for Ragweed-Allergic Rhinitis in an Environmental Exposure Chamber

Rhinitis, Allergic, Seasonal

Canada
Faes Farma, S.A.
Allied Research International

Completed

PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)

Seasonal Allergic Rhinitis | Hay Fever | Rhinoconjunctivitis

Canada
Red Maple Trials Inc.
Ottawa Allergy Research Corporation

Completed

Red Maple Trials Cat Allergen Natural Exposure Chamber Validation in Cat-allergic Subjects (NEC)

Allergic Rhinitis | Rhinoconjunctivitis | Exposure

Canada
The University of Texas Medical Branch, Galveston

Completed

Innate Neutrophilic Nasal Inflammation in a Pollen Exposure Chamber (Pollen)

Allergic Rhinitis
Corcept Therapeutics

Completed

Crossover Drug-Drug Interaction Study to Determine Effects of Cytochrome P450 3A on Exposure to Mifepristone and Its Metabolites

Healthy

United States
Allergopharma GmbH & Co. KG
Inflamax Research Incorporated

Terminated

Evaluation of the Utility of an EEC for Assessing Efficacy of SIT in Pivotal Clinical Trials

Healthy Volunteers | Allergic Rhinoconjunctivitis

Canada
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Cat Pilot Study - Environmental Exposure Chamber (EEC) vs. Nasal Allergen Challenge (NAC)

Hypersensitivity, Immediate

Canada
Designed Altobaric Technology, Incorporated

Withdrawn

Effect of Repeated Exposures to Compressed Air on Patients With AIDS (DANET1)

AIDS

United States
Adom Advanced Optical Technologies Ltd.
Inflamax Research Incorporated

Completed

Evaluation of Dry Eye by Tear Film Imager in a Low Humidity Environmental Exposure Chamber (TFI-LH16) (TFI-LH16)

Dry Eye

Canada
ALK-Abelló A/S
Inflamax Research Incorporated

Completed

A Dose-response Evaluation of the SQ Tree SLIT-tablet Using an Environmental Exposure Chamber

Allergic Rhinoconjunctivitis

Canada
AstraZeneca

Completed

Study Using the Environmental Exposure Chamber (EEC) to Assess the Onset of Action of Ciclesonide, Applied as a Nasal Spray in Treatment of Seasonal Allergic Rhinitis (BY9010/M1-406)

Rhinitis, Allergic, Seasonal | Hay Fever

Canada
Novartis

Completed

A Study to Compare the Efficacy of QAV680 Against Placebo in Treating Seasonal Allergic Rhinitis in an Environmental Exposure Chamber

Seasonal Allergic Rhinitis

Canada
Novartis Pharmaceuticals

Completed

A Clinical Trial to Test How Well Two Drugs, QAW039 and Montelukast Work Both Individually and Together, to Target Allergic Rhinitis Using an Environmental Exposure Chamber

Allergic Rhinitis

Germany
ALK-Abelló A/S

Completed

Evaluation of the Efficacy and Safety of AVANZ® Phleum Pratense in Grass Pollen-induced Allergic Rhinitis During Controlled Exposure in an Environmental Challenge Chamber (AV-G-03)

Grass Pollen Induced Allergic Rhinoconjunctivitis

Germany
Oklahoma State University Center for Health Sciences
The Boeing Company

Completed

Effects of Mild Hypobaric Hypoxia on Sleep and Post-sleep Performance

Hypoxia | Environmental Sleep Disorder | Altitude

United States
Circassia Limited
Adiga Life Sciences, Inc.

Completed

Evaluating the Efficacy of Ragweed-SPIRE Following Exposure to Ragweed Allergen in an Environmental Exposure Chamber

Seasonal Allergic Rhinitis

Canada
Eleven Biotherapeutics

Completed

A Single Center Study for the Treatment of Moderate to Severe Allergic Conjunctivitis (EBI-005-AC-1)

Allergic Conjunctivitis

Canada
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Monocenter 6-period Study in Patients With Seasonal Allergic Rhinitis to Birch Pollen to Establish a Challenge Model With Natural Birch Pollen in an Environmental Challenge Chamber (ECC)

Seasonal Allergic Rhinitis
Mati Therapeutics Inc.

Terminated

A Study to Evaluate the Safety and Efficacy of the QLT Proprietary Olopatadine-PPDS in Subjects With Seasonal Allergic Conjunctivitis to Ragweed in an Environmental Exposure Chamber Model.

Seasonal Allergic Conjunctivitis to Ragweed

Canada
Stallergenes Greer

Completed

Efficacy and Safety of 100IR, 300IR, 500IR Sublingual House Dust Mite (HDM) Tablets in Allergic Rhinitis Environment Exposure Chamber Model

House Dust Mites Allergic Rhinitis

Canada
Circassia Limited
Cetero Research, San Antonio; Adiga Life Sciences, Inc.

Completed

ToleroMune House Dust Mites (HDM) Exposure Chamber Study

Rhinoconjunctivitis

Canada
Alcon Research

Completed

Safety and Efficacy of AL-53817 Nasal Spray Solution

Allergies | Nasal Allergies

United States
Singapore Eye Research Institute
Singapore National Eye Centre

Completed

Controlled Adverse Environment: A Pilot Study to Evaluate Tear Film Stability and Tear Evaporation

Environmental Exposure

Singapore
Ligand Pharmaceuticals

Completed

Compare Captisol-Enabled (CE) Budesonide + Azelastine Nasal Solution and Rhinocort Aqua + Astelin in an Environmental Exposure Chamber (EEC) Study of Allergic Rhinitis

Seasonal Allergic Rhinitis

Canada
Faes Farma, S.A.

Completed

A Randomized, Double-Blind, 4-way Crossover Study to Evaluate the Efficacy of Bilastine in the Vienna Challenge Chamber

Seasonal Allergic Rhinitis

Austria
Circassia Limited
Cetero Research, San Antonio; Adiga Life Sciences, Inc.

Completed

ToleroMune Ragweed Exposure Chamber Study

Ragweed Allergy

Canada
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Validation of an Environmental Exposure Chamber for Inhalation Studies With House Dust Mite Allergen in Patients With Allergic Rhinitis

Allergy to House Dust Mite

Germany

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