Search clinical trials for: FXa inhibitor

Total 67767 results

AstraZeneca

Not yet recruiting

FAITH - Factor XA Inhibitor-Related InTracranial Haemorrhage (FAITH)

InTracranial Haemorrhage
VarmX B.V.

Recruiting

Single Dose Trial of VMX-C001 in Healthy Subjects With and Without FXa Direct Oral Anticoagulant

Coagulation Disorder

Netherlands
Alexion Pharmaceuticals, Inc.

Completed

Trial of Andexanet Alfa in ICrH Patients Receiving an Oral FXa Inhibitor

Acute Intracranial Hemorrhage

Canada, Denmark, Italy, Netherlands, Spain, United States, Belgium, Switzerland, Germany, Hungary, Russian Federation, Czechia, France, United Kingdom, Israel, Austria, Norway, Latvia, Finland, Poland, Sweden, Portugal, Greece, Lithuania
Portola Pharmaceuticals

Completed

A Study in Older Subjects to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Apixaban

Bleeding

United States
Portola Pharmaceuticals

Completed

Single Ascending Dose Study of PRT064445, a Factor Xa (fXa) Inhibitor Antidote

Healthy

United States
Alexion

Terminated

Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery (Annexa-S)

Surgery

United States, Germany, Israel, France, Austria, Japan
Portola Pharmaceuticals

Completed

The Effect o f Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Betrixiban, an Oral FXa Antagonist

Hepatic Impairment

United States
Portola Pharmaceuticals

Completed

A Study in Older Subject to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Rivaroxaban

Bleeding

United States
Astellas Pharma Inc

Completed

Prevention of Recurrence of Venous Thromboembolism in Patients With a History of Venous Thromboembolism

Venous Thromboembolism

Japan
Astellas Pharma Inc

Completed

Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery

Venous Thromboembolism

Japan, Taiwan, Thailand
Astellas Pharma Inc

Completed

YM150 for Prevention of Venous Thromboembolism in Patients With Acute Medical Illness

Venous Thromboembolism

Japan
Astellas Pharma Inc

Completed

A Study to Assess the Effect of YM150 for Prevention of Venous Thromboembolism in Patients Undergoing Major Abdominal Surgery

Venous Thromboembolism

Japan
Astellas Pharma Inc

Completed

Prevention of Venous Thromboembolism in Subjects Undergoing Hip Fracture Surgery or Surgery in the Lower Extremities

Venous Thromboembolism

Japan
Astellas Pharma Inc

Completed

Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Hip Replacement Surgery

Venous Thromboembolism

Japan, Korea, Republic of, Taiwan, Thailand
National University Hospital, Singapore

Not yet recruiting

A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers (VALUE-CHECK)

Carcinoma, Hepatocellular | Gastric Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Oesophageal Cancer | GastroEsophageal Cancer

Singapore
University of Utah
Kaiser Permanente

Not yet recruiting

A Tool to Help Patients With Muscle Symptoms After Taking a Statin Medication.

Cardiovascular Diseases | Hypercholesterolemia | Placebo Effect | Pharmacists | Hydroxymethylglutaryl-CoA Reductase Inhibitors
Ascentage Pharma Group Inc.

Not yet recruiting

A Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients With CML (POLARIS-2)

Chronic Myeloid Leukemia | CML | CML, Chronic Phase

United States
Sunnybrook Health Sciences Centre

Not yet recruiting

Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE) (RELIFE)

Knee Osteoarthritis

Canada
Shanghai Zhongshan Hospital

Not yet recruiting

PD-1/PD-L1 Inhibitors and Anti-angiogenic Therapy Combined With/Without TACE/HAIC in Patients With BCLC B/C Hepatocellular Carcinoma Beyond Up-to-7

Hepatocellular Carcinoma
National Cancer Institute (NCI)

Not yet recruiting

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Undifferentiated Pleomorphic Sarcoma | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Bayer
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn More About How Well 8 Milligram Aflibercept Works and How Safe it is in Chinese Participants With Diabetic Macular Edema (PHOTONiC)

Diabetic Macular Edema
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
Chen Xiaoping

Not yet recruiting

Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model

HCC
Ain Shams University

Recruiting

Renoprotective Effects of Dapagliflozin Versus Pentoxiphylline in Chronic Kidney Disease Patients

Chronic Kidney Diseases

Egypt
University of Santiago de Compostela
Hospital Clinico Universitario de Santiago

Not yet recruiting

An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures

Bacteremia | Endocarditis

Spain
Merck Sharp & Dohme LLC

Not yet recruiting

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

NSCLC | Non-small Cell Lung Cancer
Bristol-Myers Squibb

Not yet recruiting

Observational Study of Muscle Invasive Urothelial Carcinoma Participants Treated With Adjuvant Nivolumab in France (URADJ)

Urothelial Carcinoma

France
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

M9466 as Single Agent or in Combination With Tuvusertib in Advanced Solid Tumors (DDRiver 501)

Advanced Solid Tumor

United States, Germany
Mayo Clinic

Not yet recruiting

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Cholangiocarcinoma | Refractory Cholangiocarcinoma | Stage III Hilar Cholangiocarcinoma AJCC v8 | Stage IV Hilar Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
Peking University Cancer Hospital & Institute

Recruiting

RC48 Treatment for Platinum Sensitive Recurrent Ovarian Cancer With HER2 Expression

Fallopian Tube Carcinoma | Ovarian Carcinoma | Primary Peritoneal Carcinoma

China
Yanyan Liu

Recruiting

Linperlisib Combined With Chidamide in Patients With PTCL

Peripheral T-cell Lymphoma

China
British University In Egypt

Not yet recruiting

Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers

Treatment Compliance | Aphthous Stomatitis (Major) (Minor)

Egypt
Pfizer

Not yet recruiting

A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Melanoma and Skin Cancer Trials Limited

Not yet recruiting

Neoadjuvant PD-1 Inhibitor and EGFR Inhibitor in Locally Advanced Cutaneous Squamous Cell Carcinoma (NEOPECS)

Locally Advanced Cutaneous Squamous Cell Carcinoma
Bronx VA Medical Center

Not yet recruiting

Dose Optimization of MDMA-Assisted Therapy for PTSD (DosOp)

Posttraumatic Stress Disorder
Ain Shams University

Recruiting

Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females

Polycystic Ovary Syndrome | Infertility, Female

Egypt
Jeffrey Zonder

Not yet recruiting

DapagliFLOzin in Renal AL Amyloidosis (FLORAL) (FLORAL)

Renal AL Amyloidosis

United States
Boehringer Ingelheim

Not yet recruiting

A Study in Healthy Men to Test Whether Esomeprazole Influences the Amount of BI 3000202 in the Blood

Healthy
Beijing 302 Hospital

Not yet recruiting

Adebrelimab Plus Apatinib and Etoposide for the Treatment of HER2-Negative Breast Cancer Brain Metastasis

HER2-negative Breast Cancer Brain Metastases

China
University of Cologne
AstraZeneca

Not yet recruiting

Maintenance Durvalumab (MEDI4736) and Olaparib (AZD2281) After Standard 1st Line Treatment (Carboplatin/Cisplatin, Etoposide, Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC) (GUIDANCE)

Small Cell Lung Carcinoma
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Fruquintinib and Albumin-paclitaxel Combined With or Without PD-1 Antibody in 2nd-line Treatment of G/GEJ Adenocarcinoma

Gastric Cancer
Vanderbilt University Medical Center

Not yet recruiting

Comparison of Amitriptyline to Lifestyle Modification as Intervention for Vestibular Migraine (RCTVM)

Vestibular Migraine

United States
University of Kansas Medical Center

Not yet recruiting

Dose-escalation Study of Ultra-high Dose Ablative Radiosurgery With Immunotherapy for Bulky Metastatic Cancer Patients

Solid Tumor

United States
Zhiyong Huang

Not yet recruiting

Lenvatinib and Adebrelimab Combined With GEMOX in the Perioperative Treatment of Potentially Resectable Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma

China
Necmi Kadıoğlu Hospital

Recruiting

Caudal Anesthesia Versus Local Anesthesia in Hypospadias

Children | Hypospadias | Hypospadias, Coronal | Caudal Anesthesia

North Macedonia, Russian Federation, Turkey
Shanghai University of Traditional Chinese Medicine
Shanghai Minimally Invasive Surgery Center

Not yet recruiting

Clinical Evaluation of Acupuncture Treatment on Alzheimer's Disease in APOE e4 Carriers and Non-Carriers

Cognitive Impairment | Alzheimer Disease

China
Bayer

Not yet recruiting

A Study to Learn About Whether BAY H006689 Causes an Allergic Reaction When Applied as a Topical Gel in Healthy Participants

Pain | Healthy Volunteers

United States
Peter MacCallum Cancer Centre, Australia
AbbVie

Not yet recruiting

MRD-Directed Consolidation With Epcor-only or Epcor-R2 Post Anti-CD19 CAR TCell Therapy for Large B-Cell Lymphoma (EpLCART)

Relapsed/Refractory Large B-cell Lymphoma

Australia
Acepodia Biotech, Inc.

Not yet recruiting

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States
Gruppo Oncologico Italiano di Ricerca Clinica

Recruiting

Durvalumab With Carboplatin and Etoposide Chemotherapy in Pulmonary Large-cell Neuroendocrine Carcinoma (LCNEC) (DUPLE)

Pulmonary Large-cell Neuroendocrine Carcinoma

Italy

Search clinical trials for: FXa inhibitor

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