Search clinical trials for: Failed other treatments

Total 25024 results

Evopoint Biosciences Inc.
Merck Sharp & Dohme LLC

Recruiting

Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)

Carcinoma | Cervical Cancer | Prostate Cancer | Squamous Cell Carcinoma of Head and Neck | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Urothelial Carcinoma | Other Solid Tumors

China
Innovaderm Research Inc.
Amgen

Completed

Safety and Efficacy of Etanercept in Patients With Psoriasis Who Failed to Respond to Other Biologic Treatments

Psoriasis

Canada
Polaris Group

Completed

Ph 1 Study of ADI PEG 20 in Pediatric Subjects Who Are Argininosuccinate Synthetase (ASS) Deficient

Argininosuccinate Synthetase Deficient

United States
Daiichi Sankyo, Inc.

Completed

Study of CS-1008 in Combination With FOLFIRI in Patients Who Have Failed Other Treatments

Metastatic Colorectal Cancer

United States
Myrexis Inc.

Completed

Safety Study of MPC-3100 in Cancer Patients Who Have Failed Other Treatments

Cancer

United States
Duke University
Temple University

Not yet recruiting

ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments

Amyotrophic Lateral Sclerosis ALS

United States
Pfizer

Not yet recruiting

A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Medstar Health Research Institute

Not yet recruiting

Randomized Evaluation for Failed TAVR (REVIVE-TAVR)

Prosthesis Failure | Prosthetic Valve Malfunction | Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure
TC Erciyes University

Recruiting

Effect of Different Irrigation Solutions on Postoperative Pain and Lesion Healing

Endodontic Disease

Turkey
Universidad de Colima

Recruiting

Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics (FAPD_RCT)

Functional Gastrointestinal Disorders | Functional Abdominal Pain Syndrome | Irritable Bowel Syndrome Variant of Childhood

Mexico
Pfizer

Recruiting

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Multiple Myeloma

United States, Japan, Spain, Canada, Finland, Argentina, Norway
Federal University of Minas Gerais

Recruiting

Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome

Burning Mouth Syndrome

Brazil
Universidad Nacional de Entre Rios
National Council of Scientific and Technical Research, Argentina

Recruiting

Effectiveness of Platelet-rich Plasma Treatment of Knee Osteoarthritis

Knee Osteoarthritis

Argentina
Parc de Salut Mar
Hospital Clinic of Barcelona; Hospital Universitario Fundación Jiménez Díaz; Hospital... and other collaborators

Recruiting

Effectiveness of Treatments for Massive Rotator Cuff Tears: Mixed Methodology.

Shoulder Disease | Massive Rotator Cuff Tears

Spain
Unity Health Toronto
Canadian Institutes of Health Research (CIHR); Health Canada

Recruiting

Canadian Adaptive Platform Trial of Treatments for COVID-19 in Community Settings (CanTreatCOVID)

COVID-19

Canada
Bristol-Myers Squibb

Recruiting

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive HCM) (DISCOVER-HCM)

Obstructive Hypertrophic Cardiomyopathy

United States, Puerto Rico
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

Norway, United States, Spain, United Kingdom, Canada
Alabama Physical Therapy & Acupuncture
Universidad Rey Juan Carlos

Recruiting

Periosteal Electrical Dry Needling for Knee Osteoarthritis

Knee Osteoarthritis

United States
Menoufia University

Not yet recruiting

Different Induction Protocols in PCOS After Clomiphene Citrate Failed Pregnancy in Non-IVF Cycles

Infertility, Female
Novartis Pharmaceuticals

Recruiting

A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting

Hypercholesterolemia

Germany
Shanghai Minimally Invasive Surgery Center
Wuxi Branch of Ruijin Hospital; Shanghai OneTar Biomedicine Co., Ltd.

Not yet recruiting

The Clinical Efficacy of Drug Sensitive Neoadjuvant Chemotherapy Based on Organoid Versus Traditional Neoadjuvant Chemotherapy in Advanced Rectal Cancer

Neoadjuvant Therapy
China Medical University Hospital
National Health Research Institutes, Taiwan

Recruiting

Combination of NMDA-enhancing and Anti-inflammatory Treatments for Ultra-resistant Schizophrenia

Schizophrenia

Taiwan
Shanghai Zhongshan Hospital

Recruiting

Eradication Efficacy and Safety of Two Rescue Treatments for Helicobacter Pylori Infection

H. Pylori Infection

China
Regeneron Pharmaceuticals

Recruiting

A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Patients With Multiple Myeloma That is Resistant to Current Standard of Care Treatments

Multiple Myeloma

United States, Spain, France, Greece
China Medical University Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Combination of NMDA-enhancing and Antioxidant Treatments for Schizophrenia

Schizophrenia

Taiwan
China Medical University Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Combination of NMDA-enhancing and Anti-inflammatory Treatments for Schizophrenia

Schizophrenia

Taiwan
Merck Sharp & Dohme LLC

Recruiting

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008)

Colorectal Cancer

United States, Belgium, Canada, Germany, Italy, Korea, Republic of, Poland, Russian Federation, Spain, Turkey, United Kingdom, France, Denmark, Romania, Estonia, Hungary, Guatemala, Costa Rica, Lithuania, Greece, Colombia, Netherl...
Italian Sarcoma Group
Associazione Italiana Ematologia Oncologia Pediatrica

Recruiting

Observational Study in Localized Osteosarcoma (ISG Os2Oss)

Localized Osteosarcoma

Italy
Italian Sarcoma Group

Recruiting

Observational Study on Skeletal Ewing's Sarcoma (EWOss)

Ewing Sarcoma of Bone

Italy
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Drug-eluting Beads Bronchial Arterial Chemoembolization in Stage II-III Non-small-cell Lung Cancer Patients Failed, Refused or Ineligible to Receive Standard Treatments

Carcinoma, Non-Small-Cell Lung
Solve ME/CFS Initiative

Recruiting

Solve Together: A Data Collection Platform for the Collection of Patient and Control Health Information to Support Future Research That Will Accelerate Understanding of the Causes of and Possible Treatments for ME/CFS and Other Chronic Diseases, Including Post-viral Illnesses

ME/CFS | Post-Acute COVID-19 Syndrome

United States
Italian Sarcoma Group

Recruiting

Study on Clinical Features and Outcomes of Breast Sarcoma (Breast-Sarc)

Breast Sarcoma

Italy
Assistance Publique - Hôpitaux de Paris
Swedish Orphan Biovitrum

Recruiting

A Trial Comparing the Efficacy and Safety of Anakinra Versus Intravenous Immunoglobulin (IVIG) Retreatment, in Patients With Kawasaki Disease Who Failed to Respond to Initial Standard IVIG Treatment (ANACOMP)

Kawasaki Disease

France
Sahlgrenska University Hospital, Sweden

Recruiting

Local Recurrence Due to Rectal Cancer in Sweden (LERIS)

Rectal Neoplasms

Sweden
Novartis Pharmaceuticals

Recruiting

Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments

Advanced Solid Tumors

Switzerland, Belgium, Italy, Spain, Germany, Hong Kong, Hungary, Korea, Republic of, China, Czechia, Canada, United States, France, Poland, Thailand, Netherlands, Taiwan
Fondazione Policlinico Universitario Agostino Gemelli...
General Electric; ClinicalTrialCenter; FerrarioDati

Recruiting

Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress Syndrome (IPERPEEP)

Respiratory Distress Syndrome, Adult

Italy
Shanghai Henlius Biotech

Recruiting

A Clinical Study to Evaluate HLX10 Monotherapy for the Treatment of MSI-H or dMMR Solid Tumors That Failed to Respond to Standard Therapy

MSI-H Solid Malignant Tumor

China
Massachusetts General Hospital

Recruiting

A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth

Mood Disorders | Mood Disturbance | Alternative Treatment | Natural Supplements

United States
Massachusetts General Hospital
Demarest Lloyd Jr. Foundation

Recruiting

Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)

Autism Spectrum Disorder | Autism | Non-verbal Learning Disorder

United States
Zimmer Biomet

Recruiting

Comprehensive Segmental Revision System

Rheumatoid Arthritis | Trauma | Oncology | Degenerative Disease | Revision Surgery

Canada, Denmark, United Kingdom
Novartis Pharmaceuticals

Recruiting

Study to Allow Patients Previously Participating in a Novartis Sponsored Trial to Continue Receiving Capmatinib Treatment as Single Agent or in Combination With Other Treatments or the Combination Treatment Alone

Advanced Solid Tumors Which Are cMET-dependent

Germany, Korea, Republic of, Belgium, Italy, Singapore, United States, Denmark, Spain, France, Canada
Swiss Dermatology Network for Targeted Therapies

Recruiting

Swiss Dermatology Network of Targeted Therapies (SDNTT) (SDNTT)

Psoriasis

Switzerland
Invivyd, Inc.
In Expanded Access, treating physicians are the Sponsors

No longer available

Provide Pre-approval Single-patient Expanded Access (Compassionate Use) of VYD222 for Patients With Symptomatic COVID-19 Refractory to Other Treatments

COVID-19
Texas Scottish Rite Hospital for Children
Johns Hopkins University; Mayo Clinic; Baylor College of Medicine; Children's Hospital... and other collaborators

Enrolling by invitation

Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease (IPSG1)

Legg Calve Perthes Disease

United States, Canada, Puerto Rico, Sweden, Ireland, Norway, Spain, Poland, Australia, Brazil, China, Germany, India, United Kingdom, Switzerland
Eli Lilly and Company

Active, not recruiting

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Relapsed Solid Tumor | Refractory Solid Tumor

United States, Canada, France, Australia, Belgium, Germany, Spain, Italy
Celgene

Active, not recruiting

A Study to Determine Dose, Safety, Tolerability, Drug Levels, and Efficacy of CC-220 Monotherapy, and in Combination With Other Treatments in Participants With Multiple Myeloma

Multiple Myeloma

United States, Australia, Canada, France, Germany, Israel, Italy, Japan, Netherlands, Spain, United Kingdom
Georgia State University
Multiple Sclerosis Center of Atlanta

Active, not recruiting

Effects of Ocrevus in Relapsing Multiple Sclerosis (MOBILE-RMS)

Relapsing Multiple Sclerosis

United States
Parc de Salut Mar

Active, not recruiting

Asthma Research in Children and Adolescents (ARCA)

Asthma in Children | Persistent Asthma | Asthma Exacerbation

Spain
Bayer

Completed

A Study to Learn More About How Radium-223 is Being Used With Other Treatments in European Patients Who Have Not Received Radium-223 Before (DIRECT)

Bone Metastatic Castration-resistant Prostate Cancer

Germany, Netherlands, Denmark
Italian Sarcoma Group

Completed

Study in Low Risk Gastrointestinal Stromal Tumor (GISTs) (RetroGIST)

GIST

Italy

Search clinical trials for: Failed other treatments

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