Search clinical trials for: Fibroblast Activation Protein

Total 23941 results

Mara Veenstra, MD
UMC Utrecht; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Not yet recruiting

The Effect of [18F] F-FAPI PET-CT on Management in Patients With Proximal Cholangiocarcinoma (FAPIChol)

Cholangiocarcinoma
Henan Institute of Cardiovascular Epidemiology

Not yet recruiting

SPECT Fibroblast Activation Protein Imaging in Patients With Cardiac Disease

Myocardial Fibrosis
Cancer Institute and Hospital, Chinese Academy...
Peking University; Peking University Cancer Hospital & Institute

Recruiting

68Ga-TCR-FAPI PET/CT Guided Precision Surgery for MTC

Surgery | Medullary Thyroid Cancer | Fibroblast Activation Protein Inhibitor | Prositron Emission Tomography

China
Erasme University Hospital

Recruiting

Role of the Fibroblast Activation Protein (FAP) as Biomarker of Fibrotic Lung Diseases (FAPIPET)

Idiopathic Pulmonary Fibrosis | Pulmonary Fibrosis | FAP | Lung Fibrosis

Belgium
Guangdong Provincial People's Hospital
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Recruiting

A Novel 68Ga Labeled FAP Ligand PET/CT in Patients With Various Malignant Tumors (68Ga-GPFAPI)

Cancer | Metastatic Cancer | Malignant Neoplasm | Tumors

China
Central Hospital, Nancy, France

Not yet recruiting

Study of Liver Fibrosis Stage Assessment by Fibroblast Activation Protein Imaging in Patients With Biopsy for Suspected or Proven Nonalcoholic Steatohepatitis (HEFITEP)

Non-alcoholic Steatohepatitis
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

68 Gallium-Fibroblast Activating Protein Inhibitors-46 Positron Emission Tomography - Computerized Tomography for Molecular Assessment of Fibroblast Activation and Risk Assessment in Solid Tumors (FAPI)

Solid Tumor, Unspecified, Adult

Italy
Jules Bordet Institute

Recruiting

Molecular Imaging of FAP Expressing Cancer-associated Fibroblasts in NSCLC Treated With Immune-checkpoint Inhibitors (LIFE)

Non Small Cell Lung Cancer

Belgium
Cancer Institute and Hospital, Chinese Academy...
Peking University; Peking University Cancer Hospital & Institute

Recruiting

68Ga-TCR-FAPI PET/CT in Patients With Various Types of Cancer

Malignant Tumor | Positron Emission Tomography | Fibroblast Activation Protein Inhibitor

China
Jules Bordet Institute

Recruiting

Ga68-FAPI-46 PET/CT for Preoperative Assessment of Peritoneal Carcinomatosis (FAPeCa)

Cancer | Peritoneal Carcinomatosis

Belgium
Amsterdam UMC, location VUmc
Leiden University Medical Center; Dutch Cancer Society

Recruiting

[68Ga]Ga-FAPI-46 Positron Emission Tomography (PET) Scan to Improve the Imaging of Pancreatic and Bile Duct Cancer (PANSCAN-1)

Pancreatic Cancer | Cholangiocarcinoma

Netherlands
Aalborg University Hospital

Recruiting

[68Ga]Ga-FAPI-46 PET/CT in Ovarian Cancer

Ovarian Cancer

Denmark
Aalborg University Hospital

Recruiting

[68Ga]Ga-FAPI PET/CT in Gastric and Gastroesophageal Junctional Cancer

Cancer | Gastric Cancer | Gastro Esophageal Junctional Cancer

Denmark
Nanjing First Hospital, Nanjing Medical University

Recruiting

Study of Novel PET Tracer Gallium [68Ga]/ Fluorine [18F] -FAPI-04 in the Diagnosis of Cardiovascular Diseases

Myocardial Fibrosis

China
SOFIE

Recruiting

Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers (18F-FAPI-74 GI)

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Cholangiocarcinoma | Pancreatic Ductal Adenocarcinoma | Gastrointestinal Cancers

United States
Zhongnan Hospital

Recruiting

Fibroblast Activation Protein Inhibitor PET/CT Imaging in Malignant Tumor of Digestive System

Gastrointestinal Cancer

China
The National Center of Oncology, Azerbaijan
SOFIE INC

Recruiting

Comparison of [68Ga]GaFAPI-46 PET/CT and [18F]FDG PET/CT Findings in Breast Carcinoma

Breast Neoplasms | Positron Emission Tomography | Fluorodeoxyglucose F18 | Fibroblast Activation Protein Inhibitor

Azerbaijan
Zhongnan Hospital

Recruiting

The Function of PET Molecular Imaging Targeting Fibroblast Activation Protein in the Hepatobiliary Malignancies

Hepatobiliary Diseases

China
SOFIE

Recruiting

Study of [68Ga]FAPI-46 PET in Patients With Pancreatic Ductal Carcinoma (FAPI-46 PDAC)

FAP | PDAC - Pancreatic Ductal Adenocarcinoma

United States
Thomas Hope
Clovis Oncology, Inc.

Recruiting

Imaging of Pathologic Fibrosis Using 68Ga-FAP-2286

Myocardial Fibrosis | Pulmonary Fibrosis | Liver Fibrosis

United States
Zhongnan Hospital

Recruiting

68Ga-FAPI PET/CT in Malignant Tumors

Malignant Neoplasm | PET/CT | Fibroblast Activation Protein Inhibitor

China
Wuhan Union Hospital, China

Recruiting

Clinical Application of Fibroblast Activation Protein PET/MRI in Liver Fibrosis

Magnetic Resonance Imaging | Liver Fibrosis | Positron Emission Tomography

China
Wuhan Union Hospital, China

Recruiting

Clinical Application of Fibroblast Activation Protein PET/MRI for Diagnosis and Staging in Malignant Tumors

Malignant Neoplasm

China
Stanford University

Not yet recruiting

68-Ga-FAPI PET Imaging in Malignancy

Cancer

United States
The First Affiliated Hospital of Anhui Medical...
National Natural Science Foundation of China

Suspended

FAP PET/CT or PET/MR Production in the Diagnosis, Staging, and Efficacy Assessment of Malignant Tumors Application

Malignant Tumors | Positron-Emission Tomography

China
Molecular Partners AG

Terminated

First-in-human Safety and Tolerability of MP0317 in Patients With Relapsed/Refractory Advanced Solid Tumors

Advanced Malignant Solid Tumor

Netherlands, France
Novartis Pharmaceuticals

Active, not recruiting

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors (LuMIERE) (LuMIERE)

Solid Tumor

United States
POINT Biopharma

Active, not recruiting

FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER)

Soft Tissue Sarcoma | Colorectal Cancer | Esophageal Cancer | Cholangiocarcinoma | Head and Neck Squamous Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Melanoma (Skin)

United States, Canada
Zhongnan Hospital

Enrolling by invitation

Exploring the Application Value of PET Molecular Imaging Targeting FAP in Oral Squamous Cell Carcinoma (FAPI-OSCC)

Oral Cancer | PET/CT | FAPI

China
Assiut University

Completed

The Role of Fibroblast Activation in Uterine Fibroid

Uterine Fibroid

Egypt
University of Zurich

Completed

Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma

Switzerland
National Cancer Institute (NCI)

Not yet recruiting

Anti-Lag-3 (Relatlinib) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Recurrent Glioblastoma
Peking Union Medical College Hospital

Recruiting

PET Imaging of Fibroblast Activation in Atherosclerosis

Atherosclerosis

China
Investigación en Hemofilia y Fisioterapia

Recruiting

Blood Flow Restriction in Improving Muscle Strength of Patients With Hemophilic Ankle Arthropathy

Hemophilia

Spain
Chang Gung Memorial Hospital

Recruiting

Evaluation of 68Ga-FAPI-46 and 18F-FDG PET/CT Imaging for Detecting Recurrent Tumor Lesions in Patients of Ovarian Cancer

Ovarian Cancer

Taiwan
Mayo Clinic

Not yet recruiting

Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery

Skin Cancer | Skin Cancer Face | Malignant Cutaneous Adnexal Neoplasm

United States
Tyra Biosciences, Inc

Recruiting

Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations (SURF201)

Solid Tumor | Intrahepatic Cholangiocarcinoma | Metastatic Cholangiocarcinoma | Locally Advanced Cholangiocarcinoma

United States
Merck Sharp & Dohme LLC

Recruiting

Study of Favezelimab Coformulated With Pembrolizumab (MK-4280A) in Participants With Selected Solid Tumors (MK-4280A-010)

Solid Tumor | Endometrial Cancer | Cutaneous Squamous Cell Carcinoma

Canada, Australia, Taiwan, Malaysia, United States, Netherlands, Turkey, France
National Cancer Institute (NCI)

Recruiting

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

Recurrent Nasopharyngeal Carcinoma | Stage IV Nasopharyngeal Carcinoma AJCC v8 | Metastatic Nasopharyngeal Carcinoma

United States, Hong Kong
The First Affiliated Hospital of Xiamen University

Recruiting

Characterizing Spondyloarthritis With 68Ga-FAPI PET/CT

Ankylosing Spondylitis | Spondyloarthritis | Axial Spondyloarthritis

China
National Cancer Institute (NCI)

Recruiting

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder for Bladder Cancer Treatment, MODERN Study

Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 | Muscle Invasive Bladder Urothelial Carcinoma

United States
The First Affiliated Hospital of Xiamen University

Recruiting

Characterizing Myositis With 68Ga-FAPI PET/CT

Myositis | Idiopathic Inflammatory Myopathies

China
Technical University of Munich
University Medicine Greifswald; Fresenius Kabi; Berlin Institute of Health

Recruiting

Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO )

Quality of Life | Muscle Atrophy | Metabolic Disturbance | ICU Acquired Weakness | Energy Malnutrition Protein | Morphological and Microscopic Findings

Germany
Ruijin Hospital

Recruiting

Fibroblast Activating Protein Inhibitor PET Imaging in Lupus Nephritis

Lupus Nephritis

China
Peking Union Medical College Hospital

Not yet recruiting

Characterizing Histiocytosis With 68Ga-FAPI PET/CT

Histiocytosis

China
Fundació Institut Germans Trias i Pujol
Germans Trias i Pujol Hospital; University of Turin, Italy; Instituto de Salud... and other collaborators

Recruiting

Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment

HIV Infection Primary

Spain
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Application of Al18F-NOTA-FAPI PET/CT in Malignant Tumors Expressing Fibroblast-activated Proteins

Malignancy

China
Peking Union Medical College Hospital

Recruiting

FAPI-PET/CT in Psoriatic Arthritis

Psoriatic Arthritis

China
All4Cure
GlaxoSmithKline

Recruiting

Impact of a Health Technology Intervention on Patient Activation in Multiple Myeloma

Multiple Myeloma | Multiple Myeloma in Relapse | Multiple Myeloma With Failed Remission | Multiple Myeloma, Refractory

United States
Oxford University Clinical Research Unit, Vietnam
Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

Recruiting

Anakinra in Dengue With Hyperinflammation ( AnaDen )

Cytokine Storm | Dengue | Severe Dengue | Macrophage Activation Syndrome | Anakinra | Dengue With Warning Signs | Anti-inflammatory Agents | Hyperinflammatory Syndrome | Immuno-modulation

Vietnam

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