Search clinical trials for: First time in humans

Total 458350 results

GlaxoSmithKline

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Oral GSK4172239D Compared With Placebo in Sickle Cell Disease Participants Aged 18 to 50 Years

Hematologic Diseases | Anaemia, Sickle Cell

United States
NorthSea Therapeutics B.V.

Completed

A Phase 1, First Time in Humans Study of NST-1024

Hypertriglyceridemia

United Kingdom
GlaxoSmithKline

Terminated

First Time in Humans (FTIH) Study of GSK3368715 in Participants With Solid Tumors and Diffuse Large B-cell Lymphoma (DLBCL)

Neoplasms

United States, Spain, Canada, Australia
Theravance Biopharma
GlaxoSmithKline

Completed

Study of GSK961081 in Healthy Volunteer Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Terminated

Investigation of GSK2879552 in Subjects With Relapsed/Refractory Small Cell Lung Carcinoma

Carcinoma, Small Cell

Spain, United States, France
GlaxoSmithKline

Completed

First-Time-in-Humans Study to Assess Safety, Pharmacokinetics & Pharmacodynamics of SB756050

Diabetes Mellitus, Type 2

United States
GlaxoSmithKline

Completed

First Study in Humans With GSK424887

Depressive Disorder and Anxiety Disorders

United Kingdom
GlaxoSmithKline

Completed

First Study in Humans With GSK206136 (NSB101909)

Depressive Disorder and Anxiety Disorders

United Kingdom
GlaxoSmithKline

Completed

A First Time In Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GSK1399686

Inflammatory Bowel Diseases

United Kingdom
GlaxoSmithKline

Completed

An Investigation of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2245035 in Healthy Volunteers and Allergic Rhinitics.

Rhinitis, Allergic, Seasonal

Netherlands
GlaxoSmithKline

Completed

A First-Time-In-Human Study in Healthy Subjects (FTIH)

Obesity

United Kingdom
University of Copenhagen

Completed

Activation of A-delta-fibres and C-fibres in a First Degree Thermal Injury in Volunteers (BI-Laser)

Healthy Subjects

Denmark
Henan University of Traditional Chinese Medicine

Unknown

A Randomized Comparative Effectiveness Research Trial of Three Treatments for COPD Patients

Pulmonary Disease, Chronic Obstructive

China
Ono Pharmaceutical Co. Ltd

Terminated

A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers

Healthy Adult Subjects

United Kingdom
Qianfoshan Hospital

Not yet recruiting

Effect of Vitamin C on Postoperative Pulmonary Complications After Intracranial Tumor Surgery

Postoperative Complications | Ventilator-Induced Lung Injury | Humans | Ascorbic Acid | Neurosurgical Procedures

China
Air Force Military Medical University, China

Recruiting

A Prospective Study: Smart Phone Application for Measure Serum Bilirubin Through Sclera Images

Jaundice | Hyperbilirubinemia | Deep Learning | Sclera

China
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Phase II Study of SSGJ-707 Combination Therapy in Advanced NSCLC Patients

First-line Advanced NSCLC Patients

China
The First Hospital of Jilin University

Recruiting

Ejaculation Abstinence Time and Assisted Reproductive Technology Outcomes

Fertilization in Vitro

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Clinical Study on the End Time of Acupuncture and Moxibustion Therapy for Peripheral Facial Paralysis

Peripheral Facial Paralysis

China
NovoCure GmbH

Recruiting

EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma

Metastatic Pancreatic Ductal Adenocarcinoma

Spain
Hutchmed

Recruiting

A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

China
The First Hospital of Jilin University

Recruiting

Real-time Artificial Intelligence-based Endocytoscopic Diagnosis of Colorectal Neoplasms

Colorectal Neoplasms

China
ViiV Healthcare
GlaxoSmithKline

Not yet recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
Anhui Provincial Hospital

Not yet recruiting

Effect of Stem Cell Infusion Time on aGVHD in Patients With Nonmalignant Hematologic Diseases

Acute Graft-versus-host Disease

China
Anhui Provincial Hospital

Not yet recruiting

Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies

Acute Graft-versus-host Disease

China
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

United States, Australia, Spain, Canada, Argentina, China, Italy, France, Japan, Taiwan, Korea, Republic of, Denmark, Germany, Hungary, Israel, Austria, Belgium, Netherlands, Brazil, Mexico, Romania, United Kingdom, Greece, Czechia, Poland and more
FengYan Jin
Sun Yat-sen University; Shandong Cancer Hospital and Institute; Affiliated Hospital... and other collaborators

Not yet recruiting

Dara-PD in the Treatment of Patients With First Relapse of Multiple Myeloma

Multiple Myeloma | First Relapse
Ohio State University Comprehensive Cancer Center

Recruiting

Online Mindfulness-Based Intervention to Decrease Pre-Procedural Anxiety Before a First-Time Screening Colonoscopy

Colorectal Carcinoma

United States
The First Affiliated Hospital with Nanjing Medical...
Huai'an First People's Hospital; Yancheng First People's Hospital

Recruiting

Clinical Study Protocol of IAV-induced Remission Followed by Consolidation Therapy With MDCyta+Ven in ND-AML

Acute Myeloid Leukemia

China
GlaxoSmithKline

Not yet recruiting

A First Time in Human Study to Evaluate the Safety and Tolerability of GSK3996401 Following Dosing With GSK4347859 in Healthy Participants

Systemic Lupus Erythematosus

United Kingdom
GlaxoSmithKline
Medicines for Malaria Venture

Recruiting

A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants

Malaria, Falciparum

United Kingdom
First Affiliated Hospital of Wannan Medical College

Recruiting

Time-restricted Enteral Nutrition Versus Continuous Enteral Nutrition in Patients With Severe Stroke

Stroke | Time Restricted Feeding

China
University of Oklahoma

Recruiting

Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation

Asthma in Children | Asthma Attack

United States
Assiut University

Recruiting

The Impact of Preoperative Aromatherapy Upon Time to First Analgesia Request After Cesarean Section

Pain

Egypt
Nanjing First Hospital, Nanjing Medical University

Recruiting

Time Interval After Gastric Emptying and Quality of Bowel Cleansing

Colonoscopy

China
Bristol-Myers Squibb

Recruiting

A Study of BMS-986315 and Nivolumab in Combination With Chemotherapy in Participants With First-line Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)

NSCLC

United States, Argentina, Chile, France, Italy, Poland, Romania, Spain, Australia
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Anhui Provincial Hospital

Not yet recruiting

UTAA09 Injection in the Treatment of Relapsed/Refractory Hematolymphatic Malignancies.

CD19-positive Relapsed or Refractory B-cell Malignancies

China
Shanghai Ming Ju Biotechnology Co., Ltd.

Not yet recruiting

Relmacabtagene Autoleucel as Second-Line Therapy in Adult Patients With Aggressive B-cell NHL

Lymphoma, Large B-Cell, Diffuse | High-grade B-cell Lymphoma | Follicular Lymphoma Grade 3B | Mediastinal B-Cell Diffuse Large Cell Lymphoma

China
Fundacion Clinica Valle del Lili
International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports...

Recruiting

Non-operative Treatment in First-time Patellar Dislocation

Patellar Dislocation

Colombia
University Hospitals Coventry and Warwickshire...

Not yet recruiting

Impact of Cardiac Prehabilitation, REhabilitation and Patient EDucation on Outcomes in Patients Undergoing First-time AF Ablation (CREED AF)

Atrial Fibrillation

United Kingdom
Nanjing Medical University

Recruiting

Evaluate Aerobic Exercise on Myocardial Fibrosis and Intestinal Flora in Dilated Cardiomyopathy Diagnosed First Time.

Myocardial Fibrosis | Cardiac Rehabilitation

China
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Effects of Early and Late Time-restricted Eating on Overweight Adults With Metabolic Syndrome

Metabolic Syndrome | Overweight and Obesity | Time Restricted Eating
Hospices Civils de Lyon

Not yet recruiting

Prevention of Vasovagal Reactions in First-time Blood Donors Using a Combined PSYchological and Physiological Approach (PREDONPSY)

Vasovagal Reaction

France
Shanghai Jiao Tong University School of Medicine

Recruiting

Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes

China
The First Hospital of Jilin University
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

The Efficacy and Safety of the RCMOP Sequential Therapy as a First-line Treatment for Patients With Intermediate-to-high Risk Diffuse Large B-cell Lymphoma Who Had Incomplete Remission.

Diffuse Large B-cell Lymphoma

China
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of QL1706 in Combination With Bevacizumab and/or Chemotherapy as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
University of Minnesota
National Heart, Lung, and Blood Institute (NHLBI); Syracuse University; Liverpool... and other collaborators

Recruiting

Community-based Communication for Blood Donation in Ghana (C-CAD)

Increase Repeat Blood Donation Attempts Among First-time Donors

United States
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY BD)

Bipolar Depression

Austria, Germany, Italy, Spain, United Kingdom
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY MDD)

Major Depressive Disorder | Treatment Resistant Depression

Austria, Germany, Italy, Spain, United Kingdom

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