Search clinical trials for: GSK3640254, dolutegravir, healthy subjects, two-way interaction, HIV

Total 40321 results

ViiV Healthcare

Completed

A Relative Bioavailability and Food-Effect Study of GSK3640254 Tablet and Capsule Formulations in Healthy Participants

HIV Infections

United States
ViiV Healthcare

Terminated

A Relative Bioavailability and Food-Effect Study of GSK3640254 Tablet and Capsule Formulations in Healthy Participants

HIV Infections

United States
ViiV Healthcare
GlaxoSmithKline

Completed

GSK3640254 First Time in Human (FTIH) Study in Healthy Volunteers

HIV Infections | Infection, Human Immunodeficiency Virus

United Kingdom
ViiV Healthcare

Completed

A Study to Compare the Relative Bioavailability of Two Different Formulations of GSK3640254

HIV Infections

United Kingdom
ViiV Healthcare

Completed

A Relative Bioavailability and Food-Effect Study of the Fixed Dose Combination of GSK3640254 and Dolutegravir (DTG) in Healthy Participants

HIV Infections

United States
ViiV Healthcare

Completed

Pharmacokinetics and Metabolism of 14 Carbon [14C]-GSK3640254

HIV Infections

United Kingdom
ViiV Healthcare

Completed

A Proof of Concept Study of GSK3640254 in Human Immunodeficiency Virus-1 (HIV-1) Infected Treatment-naive Adults

HIV Infections

Spain, France, United States, Germany, Italy, South Africa
ViiV Healthcare

Completed

Study to Evaluate the Pharmacokinetic (PK) Interactions Between GSK3640254 and Dolutegravir (DTG)

HIV Infections

United States
ViiV Healthcare

Completed

Effect of GSK3640254 on the Pharmacokinetics of a Combination Oral Contraceptive

HIV Infections

United States
ViiV Healthcare

Completed

Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)

HIV Infections

United States
ViiV Healthcare

Completed

Effect of Therapeutic and Supratherapeutic Oral Doses of GSK3640254 on Cardiac Conduction Compared to Placebo and a Single Oral Dose of Moxifloxacin

HIV Infections

United States
ViiV Healthcare

Completed

Study to Evaluate the Effect of GSK3640254 on the Pharmacokinetics of Tenofovir Alafenamide/Emtricitabine

HIV Infections

United States
ViiV Healthcare
Syneos Health

Terminated

A Clinical Trial of GSK3640254 + Dolutegravir (DTG) in Human Immunodeficiency Virus-1 Infected Treatment-naive Adults (DYNAMIC)

HIV Infections

Germany, Spain, United States, Canada, France, Italy, South Africa, Argentina, Portugal, Puerto Rico
ViiV Healthcare

Completed

Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults

HIV Infections

United States
ViiV Healthcare

Terminated

A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults (DOMINO)

HIV Infections

Spain, France, United States, Canada, Portugal, Germany, Italy, South Africa, Argentina, Russian Federation, Switzerland
University of Massachusetts, Worcester
National Institute on Drug Abuse (NIDA); University of Zambia

Recruiting

Zambia Healthy Choices Project for Emerging Adults Living With HIV

Pre-Exposure Prophylaxis

Zambia
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
University of Bologna

Not yet recruiting

Effect of a Dietary Supplement on Lipid Pattern, Indexes of NAFLD and Systemic Inflammation in Healthy Subjects With Suboptimal LDL-C Levels

Inflammation | Hypercholesterolemia

Italy
Pfizer

Not yet recruiting

A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Healthy Participants

Healthy Participants | Biological Availability
Fore Biotherapeutics

Recruiting

A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Volunteers.

Healthy Volunteer

United States
ViiV Healthcare

Recruiting

A Study to Investigate the Effect of Food on the Bioavailability of a Capsid Inhibitor (CAI) in Male and Female Healthy Participants

HIV Infections

United States
Atea Pharmaceuticals, Inc.

Not yet recruiting

Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/Ruzasvir

Healthy Volunteer Study

Canada
ViiV Healthcare
GlaxoSmithKline

Not yet recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
ViiV Healthcare

Recruiting

A Study to Investigate the Potential Drug-Drug Interaction Between VH4524184 and Oral Contraceptive (Loestrin) in Healthy Adult Female Participants

HIV Infections

United States
Fudan University

Not yet recruiting

Effectiveness of Gut Microbiota-targeted Dietary Intervention Among HIV-infected Patients

Cardiovascular Diseases | Hiv | Diet, Healthy

China
Jiangsu Aidea Pharmaceutical Co., Ltd
Chengdu Aidea Pharmaceutical Technology Co., Ltd

Recruiting

Single Ascending Dose, Food Effects and Drug-Drug Interactions of ACC017 Tablets in Healthy Adult Participants

Healthy Adult Participants

China
National Center for Advancing Translational Sciences...
Leidos Biomedical Research, Inc.; ICON Government and Public Health Solutions...

Not yet recruiting

GS-441524 for COVID-19 SAD, FE, and MAD Study in Healthy Subjects

COVID-19
City of Hope Medical Center

Not yet recruiting

CMV-specific HIV-CAR T Cells as Immunotherapy for HIV/AIDS

HIV-1

United States
Center for Innovative Public Health Research

Recruiting

Sexual Health Advocacy for Guys - a Text Messaging-based HIV Prevention Program for Guys Who Are Into Guys (SHAG)

HIV Infections

United States
National Cheng Kung University
National Health Research Institutes, Taiwan

Not yet recruiting

DDEP for Lifestyle Modification in Chronic Kidney Disease: A Randomized Feasibility Trial

Chronic Kidney Diseases

Taiwan
U.S. Army Medical Research and Development Command
National Institute of Allergy and Infectious Diseases (NIAID); Duke University and other collaborators

Not yet recruiting

Evaluation of Safety and Immunogenicity of Ad26.Mos4.HIV and CH505 TF chTrimer Combination in Healthy Adults (RV591)

Human Immunodeficiency Virus

Uganda
ViiV Healthcare

Recruiting

A Study to Investigate the Relative Bioavailability and Food Effect of an Oral Capsid Inhibitor Tablet Formulation Compared With Other Oral Tablet Formulations in Male and Female Healthy Participants

HIV Infections

United Kingdom
ViiV Healthcare

Recruiting

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Two Different Formulations of Long-acting Cabotegravir in Healthy Adult Participants

HIV Infections

United States
Dr Cipto Mangunkusumo General Hospital

Recruiting

The 1000 First Day of Life : Effect of Multi Micronutrients Supplementation on Pregnancy Outcomes

Maternal-Fetal Relations | Nutrition, Healthy | Nutritional Deficiency | Maternal Care Patterns | Perinatal Outcome | Maternal Outcome

Indonesia
University of California, San Francisco
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of California... and other collaborators

Not yet recruiting

The Outreach and Prevention at ALcohol Venues in East Africa Study (OPAL-East Africa- Aim 2) (OPAL-Aim 2) (OPAL-Aim 2)

HIV/AIDS

Kenya, Uganda
University of Alberta

Recruiting

Cardiovascular Consequences of Inhaled Short-acting Beta-agonist Use

Healthy

Canada
ViiV Healthcare

Recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a Single Suspension Injection of Investigational Capsid Inhibitors Compared to Placebo in Healthy Adults

HIV Infections

United States
Liaquat University of Medical & Health Sciences

Recruiting

Evaluating the Effectiveness of Various Iron Salts and Carrier Systems in Oral Iron Therapy for Iron Deficiency and Anemia in Healthy Adults

Iron Deficiency Anemia | Iron Deficiency

Pakistan
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Evaluating the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibodies in Healthy Participants (HVTN143)

HIV Infections

South Africa
Shanxi Kangbao Biological Product Co., Ltd.
Institute of Pathogen Biology, Chinese Academy of Medical Sciences

Recruiting

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LP-98 Injection in Healthy Subjects

Hiv

China
Temple University

Recruiting

Forging Sustainable Solutions for HIV Continuity of Care Through Medical-legal Partnerships

Organizational Partnerships for Healthy Living | Standard of Care

United States
Georgetown University

Not yet recruiting

Healthy Lifestyles: A Home Based Physical Activity Intervention in Persons Living With HIV

Metabolic Syndrome | HIV-1-infection
Wake Forest University Health Sciences
National Institute on Aging (NIA); Health Resources and Services Administration...

Recruiting

Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older

HIV | Aging

United States
George Washington University
Northwestern University; Duke University; University of Utah

Recruiting

Parent-focused Intervention to Reduce HIV Risk in Gay and Bisexual Adolescents

Hiv | Sexual Health

United States
Jiangsu Simcere Pharmaceutical Co., Ltd.

Recruiting

Safety and Pharmacokinetics of SIM0417 Combined With Ritonavir in Healthy Elderly Subjects

Elder

China
Fundacion Clinic per a la Recerca Biomédica
Polymun Scientific GmbH

Recruiting

Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein SOSIP v8.2 763 Vaccine, Adjuvanted With MPLA Liposomes, in Healthy, HIV-Uninfected Adults (HIVAC-FOUND)

Healthy

Spain
Overseas Pharmaceuticals, Ltd.
Guangzhou Kangqi Medical Technology Co., LTD

Not yet recruiting

Comparative Pharmacokinetic (PK) Study of Ibuprofen and Diphenhydramine Hydrochloride MR Tablets in Healthy Adults Under Fasting Condition

Pain | Insomnia

China
Arizona State University
Foundation for Professional Development

Recruiting

Tailoring Healthy Relationships to Improve HIV Outcomes

HIV

South Africa
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy Volunteers

Weight Gain | Healthy Volunteer | Metabolic Effects | Integrase Strand Transfer Inhibitors

United States
Radboud University Medical Center
Merck Sharp & Dohme LLC; ZonMw: The Netherlands Organisation for Health Research...

Recruiting

Study on PhArmacokinetics of First liNe Antiretrovirals in Healthy Breastfeeding Volunteers (PANNA-B PK)

Hiv

Netherlands

3

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