Search clinical trials for: Genetic analysis of patients with Wet AMD who have not responded fully to anti-VEGF treatments

Total 491663 results

Vion Pharmaceuticals

Completed

VNP20009 in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Therapy

Unspecified Adult Solid Tumor, Protocol Specific

United States
Radboud University Medical Center

Completed

Study of Combination Therapy of Carboplatin -Gemcitabine Plus Bevacizumab Beyond Progression in Patients With Locally Advanced and/or Metastatic Non-small Cell Lung Cancer (NSCLC) Who Have Not Received Prior Systemic Therapy

NSCLC | Locally Advanced Non-Small Cell Lung Cancer

Netherlands
Memorial Sloan Kettering Cancer Center

Completed

Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin

Testicular Germ Cell Tumor | Ovarian Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy

Lymphoma | Leukemia | Small Intestine Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to Cisplatin

Testicular Germ Cell Tumor | Ovarian Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

ILX23-7553 in Treating Patients With Solid Tumors That Have Not Responded to Previous Therapy

Unspecified Adult Solid Tumor, Protocol Specific

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant

Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment

Lymphoma | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
National Cancer Institute (NCI)

Completed

BMS-275291 in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy

Recurrent Prostate Cancer | Bone Metastases | Hormone-resistant Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Temsirolimus in Treating Patients With Metastatic Solid Tumor or Lymphoma That Cannot Be Removed By Surgery Who Have Different Levels of Liver Function

Lymphoma | Unspecified Adult Solid Tumor, Protocol Specific | Hepatic Complications

United States
National Cancer Institute (NCI)

Completed

Liposomal Daunorubicin and SU5416 in Treating Patients With Hematologic Cancer That Has Not Responded to Initial Therapy

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Previously Treated Myelodysplastic Syndromes | Refractory Anemia With Excess Blasts | Refractory Anemia With Excess Blasts in Transformation

United States
Genentech, Inc.

Completed

A Study of Ranibizumab Administered Monthly or on an As-needed Basis in Patients With Subfoveal Neovascular Age-related Macular Degeneration (HARBOR) (HARBOR)

Age-related Macular Degeneration

United States
Alnylam Pharmaceuticals

Completed

Multi-center, Open Label, Extension Study of ALN-VSP02 in Cancer Patients Who Have Responded to ALN-VSP02 Treatment

Solid Tumors

United States, Spain
rEVO Biologics

Completed

Recombinant Human Antithrombin (rhAT) in Patients With Hereditary Antithrombin Deficiency Undergoing Surgery or Delivery

Antithrombin III Deficiency

United States, France, United Kingdom, Germany, Canada, Austria, Australia, Italy
European Organisation for Research and Treatment...

Completed

Mistletoe Lectin in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy

Unspecified Adult Solid Tumor, Protocol Specific

Germany, France
Novartis Pharmaceuticals

Completed

Intravitreal LFG316 in Patients With Advanced Age-related Macular Degeneration

Advanced Age-related Macular Degeneration

United States
European Organisation for Research and Treatment...

Withdrawn

Chemotherapy and Radiation Therapy With or Without Panitumumab in Treating Patients Who Have Undergone Surgery for Advanced Hypopharyngeal Cancer, Oropharyngeal Cancer, Laryngeal Cancer, or Oral Cavity Cancer at High Risk of Recurrence

Head and Neck Cancer
University Hospital Southampton NHS Foundation...

Unknown

Follow-Up Study of Patients Who Have Undergone Surgery for Stage I, Stage II, or Stage III Colorectal Cancer

Colorectal Cancer

United Kingdom
Bristol-Myers Squibb

Completed

A Study of Stavudine in HIV-Infected Patients Who Have Not Had Success With Other Anti-HIV Drugs

HIV Infections

United States
NeoVista

Completed

A Study to Evaluate the Neovista Ophthalmic System for the Treatment of Subfoveal CNV in Patients With AMD That Have Failed Primary Anti-VEGF Therapy (ROSE)

Wet Age-related Macular Degeneration

United States
Bristol-Myers Squibb

Terminated

A Comparison of Atazanavir and Nelfinavir, Each in Combination With 2 NRTIs, in Patients Who Have Failed Treatments Without a Protease Inhibitor

HIV Infections

United States, Mexico, Canada, Puerto Rico, Thailand
Bristol-Myers Squibb

Completed

DART II - A Phase IV Study of 3 Antiretroviral Medicines in Combination, in HIV Patients Who Have Not Been Previously Treated With Antiretroviral Therapy

HIV Infections | AIDS

United States
Bristol-Myers Squibb

Completed

DART I - A Phase IV Study of 3 Antiretroviral Medicines in Combination, in HIV Patients Who Have Not Been Previously Treated With Antiretroviral Therapy

HIV Infections | AIDS

United States
Roswell Park Cancer Institute

Completed

Genetic Changes in Patients With Non-Small Cell Lung Cancer Who Are Receiving Vinorelbine and Gemcitabine Before Surgery

Lung Cancer

United States
Bristol-Myers Squibb

Completed

Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success With Protease Inhibitor-Containing HAART Regimen(s)

HIV Infections

United States, Canada, Argentina, Belgium, Chile, Mexico, Spain, Italy, Australia, Brazil, France, Puerto Rico, United Kingdom, Netherlands, Peru
University Medical Centre Ljubljana
Institute of microbiology and immunology, Slovenia

Completed

Mixed Strain H. Pylori Infection in Patients Who Have Problems With Eradication of H. Pylori

H. Pylori Eradication Failure

Slovenia
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host...

United States
Celgene Corporation

Completed

Study Comparing Amrubicin Versus Topotecan in Patients With Small Cell Lung Cancer Who Have Responded to Prior Therapy.

Small Cell Lung Cancer

United States
Yonsei University

Unknown

Sorafenib and Erlotinib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Has Not Responded to Chemotherapy

Lung Cancer

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

Identifying Emergency Room Patients Who Have Recently Been Infected With HIV

HIV Infections

United States
Henogen
GlaxoSmithKline

Completed

A Study to Compare the Immune Response and Safety Elicited by Henogen's Adjuvanted Hepatitis B Vaccine Compared to GSK Biologicals Adjuvanted Hepatitis B Vaccine in Pre-Dialysis and Dialysis Patients Who Have Not Been Exposed to Hepatitis B.

Hepatitis B

Belgium, Czech Republic, Hungary
Bristol-Myers Squibb
Triangle Pharmaceuticals; Pharmacia and Upjohn

Terminated

The Safety and Effectiveness of Didanosine Plus Stavudine Plus Delavirdine Mesylate Plus MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors

HIV Infections

United States
Bristol-Myers Squibb
Boehringer Ingelheim; Triangle Pharmaceuticals

Terminated

The Safety and Effectiveness of Didanosine Plus Stavudine Plus Nevirapine Combined With MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors

HIV Infections

United States
Bristol-Myers Squibb

Completed

A Study of BV-araU in the Treatment of Varicella-Zoster Viral Disease (VZV) in HIV-Infected Children Who Have Not Had Success With or Who Cannot Take Other Treatments for VZV

HIV Infections | Chickenpox

United States
Eli Lilly and Company

Completed

Trial of Pemetrexed or Pemetrexed With Gemcitabine for Patients With Advanced Lung Cancer Who Are Not Eligible for Platinum-Based Chemotherapy and Have Not Previously Been Treated With Chemotherapy

Non-Small Cell Lung Cancer

Germany, Italy, United Kingdom
Eli Lilly and Company

Completed

Pemetrexed Plus Gemcitabine for Patients With Locally Advanced or Metastatic NSCLC Who Have Not Had Previous Chemotherapy.

Carcinoma, Non-Small-Cell Lung

United States
Pfizer

Completed

Assessment Of Safety And Efficacy Of SU11248 In Patients With Metastatic Colorectal Cancer Who Have Failed Selected Previous Treatments.

Colorectal Neoplasms
Chiron Corporation

Completed

Proleukin in Combination With Rituxan in Patients With Low-Grade Non-Hodgkin's Lymphoma Who Have Previously Failed Rituxan Treatments

Lymphoma, Non-Hodgkin

United States
Gilead Sciences

Completed

A Study of Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Been Treated With Anti-HIV Drugs

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With Nelfinavir

HIV Infections

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Astra USA

Unknown

A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir

HIV Infections | Cytomegalovirus Retinitis

United States
Triangle Pharmaceuticals

Unknown

A Comparison of Emtricitabine and Stavudine Used With Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico, Canada, Argentina, Chile, Mexico
Shaman Pharmaceuticals

Completed

SP-303T Applied to the Skin of Patients With Herpes Simplex Virus (HSV) Infection and AIDS Who Have Not Had Success With Acyclovir

HIV Infections | Herpes Simplex

United States
Novartis

Completed

Safety and Effectiveness of Giving Lamisil to HIV-Positive Subjects With Thrush Who Have Not Responded to Fluconazole Treatment

HIV Infections | Candidiasis, Oral

United States
Gilead Sciences

Unknown

Tenofovir Disoproxil Fumarate in HIV-Infected Patients Who Have Not Had Success With Other Anti-HIV Drug Combinations

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of ddC in Patients With AIDS or Advanced AIDS-Related Complex (ARC) Who Have Not Had Success With Zidovudine (AZT)

HIV Infections

United States
Pfizer

Completed

A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

Azithromycin in the Treatment of Cryptosporidiosis in Patients Who Have Not Had Success With Other Drugs

HIV Infections | Cryptosporidiosis

United States
Gilead Sciences

Completed

Safety and Effectiveness of Giving Adefovir (Preveon) Plus Other Anti-HIV Drugs to HIV-Infected Patients Who Have Not Responded to Other Anti-HIV Drug Combinations

HIV Infections

United States

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