Search clinical trials for: Genetic risk score

Total 35647 results

Adam S. Kibel, MD
National Cancer Institute (NCI)

Recruiting

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer (PRS)

Prostate Cancer | Polygenic Risk Score

United States
Nanyang Technological University
National University Health System, Singapore; National University of Singapore

Recruiting

Healthy Living With Online suPport & Education for Cardiovascular Disease in the Primary Care Setting (HOPE-CVD-GP)

Cardiovascular Diseases (CVD)

Singapore
VA Office of Research and Development

Recruiting

The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS) (ProGRESS)

Prostate Cancer

United States
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine (PROACT 2)

Coronary Artery Disease

United States
National University of Singapore
University Health Network, Toronto; National University Hospital, Singapore; Singapore... and other collaborators

Recruiting

HOPE-CVD-Virtual: A Virtual Trial to Evaluate the Primary Prevention of CVD

Cardiovascular Diseases

Singapore
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Change in Cardiovascular Health (PROACT 1)

Coronary Artery Disease

United States
Pediatric Clinical Research Platform
University Hospital, Geneva; University of Geneva, Switzerland

Recruiting

Mechanisms of Type 1 Diabetes Endophenotypes (METYDIA)

Genetic Predisposition to Disease | Type 1 Diabetes Mellitus

Switzerland
Odense University Hospital

Recruiting

The Danish Familial Hypercholesterolemia Organized Coronary Screening Trial (DANFOCOS)

Atherosclerosis | Familial Hypercholesterolemia

Denmark
St. Joseph's Hospital and Medical Center, Phoenix
Chandler Regional Medical Center; Mercy Gilbert Medical Center

Recruiting

Genetic Risk Stratification for Primary Prevention of CAD in Men and Pre & Post-menopausal Women

Coronary Artery Disease | Genetic Predisposition to Disease

United States
Prenome

Recruiting

OneinSeven Gestational Diabetes Genetic and Socioeconomic Risk Study

Pregnancy Complications | Pregnancy Related | Gestational Diabetes | Risk Reduction | Genetic Predisposition

United States
University Hospital Tuebingen

Recruiting

Genome-based Management of Patients in Precision Medicine (Ge-Med) Towards a Genomic Health Program (GE-MED)

Genetic Predisposition to Disease | Rare Diseases

Germany
University Hospital Tuebingen

Recruiting

Diagnostic Value of Exome/ Genome Sequencing, Conventional Methods in Rare Diseases and Familial Tumor Syndromes (EXGEFATU)

Rare Diseases | Genetic Predisposition

Germany
Sanford Health
University of Exeter; The Leona M. and Harry B. Helmsley Charitable Trust; Pacific...

Recruiting

General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery (PLEDGE)

Type 1 Diabetes | Celiac Disease

United States
University Hospital Tuebingen

Recruiting

The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4

Hereditary Spastic Paraplegia | Hereditary, Spastic Paraplegia, Autosomal Dominant

Germany
Hospital Alemão Oswaldo Cruz
Ministry of Health, Brazil; Grupo Fleury

Active, not recruiting

Impact of the Genetic Background as a Risk Factor for Atherosclerotic Cardiovascular Disease in the Brazilian Population (CV-GENES)

Cardiovascular Diseases | Stroke | Peripheral Arterial Disease | Genetic Predisposition to Disease | Acute MI

Brazil
National Institute of Neurological Disorders and...

Completed

Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility

Multiple Sclerosis

United States
Mayo Clinic

Enrolling by invitation

GENetic Risk Estimation of Breast Cancer Prior to Decisions on Preventive Therapy Uptake, Risk Reducing Surgery or Intensive Imaging Surveillance (GENRE2)

Breast Cancer

United States
Nalagenetics Pte Ltd
SJH Initiatives; MRCCC Siloam Hospitals Semanggi

Completed

Genetic and Non-Genetic Breast Cancer Risk Prediction Evaluation in Indonesian Samples

Breast Cancer

Indonesia
Institut Curie

Completed

Breast Cancer Risk After Diagnostic Gene Sequencing (BRIDGEScohort2)

Genetic Predisposition to Disease

France, Germany
Andres muñoz
Hospital Clinic of Barcelona; LEO Pharma; Hospital General Universitario Elche; Hospital Universitario Ramon y Cajal and other collaborators

Completed

A New Clinic-Genetic Risk Score for Predicting Venous Thromboembolic Events in Cancer Patient (ONCOTHROMB)

Genetic Predisposition | Cancer-associated Thrombosis

Spain
Ambry Genetics

Completed

Clinical Implementation of a Polygenic Risk Score (PRS) for Breast Cancer

Breast Cancer Risk

United States
St Mary's University College
Fulham Football Club

Completed

Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football

Tendon Injuries | Apophysitis | Genetic Predisposition | Ligament Injury | Muscle Strain | Fractures in Children

United Kingdom
Virginia Commonwealth University

Completed

Understanding Genetic Risk for Alcohol Use Disorder

Alcohol Use Disorder

United States
Wuerzburg University Hospital
Takeda

Enrolling by invitation

Fabry Disease in High-risk Patients With Left Ventricular Hypertrophy: Prevalence and Implementation of a Clinical Score (FAPREV-HCM)

Lysosomal Storage Diseases | Fabry Disease | Fabry Disease, Cardiac Variant | HCM - Hypertrophic Cardiomyopathy | Anderson Fabry Disease

Germany
Markus Perola
University of Helsinki; Institute for Molecular Medicine

Active, not recruiting

Returning Genome and Metabolome Data to FinTerveys 2017 Participants: P5.fi FinTerveys Study (P5)

Type 2 Diabetes | Coronary Heart Disease | Deep Vein Thrombosis

Finland
Mayo Clinic
CancerCare Manitoba

Completed

Genetic Risk Estimation of Breast Cancer Prior to Preventive Medication Uptake (GENRE)

Breast Cancer

United States, Canada
Aristotle University Of Thessaloniki
LABNET IAE - Private Reference Diagnostic Laboratory

Unknown

Correlation of Genetic Polymorphisms and Clinical Parameters With the Complexity of Coronary Artery Disease

Coronary Artery Disease | Coronary Arteriosclerosis | Cardiovascular Risk Factor

Greece
Vanderbilt University Medical Center
Meharry Medical College; Tennessee State University

Completed

PRecision Interventions for SMoking in the SCCS (PRISM-SCCS)

Tobacco Use Cessation

United States
Alar Irs
Tartu University Hospital; North Estonia Regional Hospital

Unknown

Proactive Cardiovascular Prevention Strategy in Subjects With High Genetic Risk (EstPerMedCV)

Cardiovascular Diseases | Primary Prevention

Estonia
NorthShore University HealthSystem
National Cancer Institute (NCI); Wake Forest University Health Sciences; Van... and other collaborators

Completed

Clinical Validity and Utility of Genomic-targeted Chemoprevention of PCa: Aim 4a

Prostate Cancer | Prostate Cancer, Familial | Hereditary Prostate Cancer
Tartu University Hospital
University of Tartu; North Estonia Medical Centre

Unknown

Personalised Risk-based Breast Cancer Prevention and Screening

Breast Cancer

Estonia
Hamilton Health Sciences Corporation
Southlake Regional Health Centre; Federal Economic Development Agency for Southern... and other collaborators

Completed

The DNA-Based Lifestyle Enhancement Trial (DNAble)

Health Behavior | Cardiovascular Risk Factor | Genetic Information

Canada
CardioDx

Completed

Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree (PREDICT)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
Brigham and Women's Hospital
Boston University; U.S. Army Medical Research and Development Command

Completed

Tau Imaging of Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy

United States
Johann Wolfgang Goethe University Hospital

Unknown

Susceptibility to Infections, Tumor Risk and Liver Disease in Patients With Ataxia Telangiectasia

Ataxia Telangiectasia

Germany
Ferrer inCode, S.L.
Instituto Valenciano de Infertilidad, IVI VALENCIA; Instituto de Investigacion... and other collaborators

Completed

Prediction of Recurrent Pregnancy Loss by a New Thrombophilia Based Genetic Risk Score (TiC-RPL)

Miscarriage, Recurrent

Spain, United Kingdom
Stanford University

Completed

Personal Genomics for Preventive Cardiology

Coronary Artery Disease

United States
AHEPA University Hospital
LABNET IAE - Private Reference Diagnostic Laboratory

Unknown

Development of a Risk Prediction Algorithm Through the Investigation of Genetic Risk Factors and the Complexity of Coronary Artery Disease to Estimate Future Risk of Cardiovascular Events: Angiographic (SYNTAX Score), Clinical and Pharmacogenetic Analysis. (GESS)

Coronary Artery Disease

Greece
Mayo Clinic
National Human Genome Research Institute (NHGRI)

Completed

Myocardial Infarction Genes (MI-GENES) Study (MI-GENES)

Myocardial Infarction | Coronary Artery Disease | Genomic Risk Communication

United States
Instituto Dante Pazzanese de Cardiologia
University of Campinas, Brazil

Completed

Genetical, Anthropometrical and Biochemical Factors Influencing High Risk Subclinical Atherosclerosis

Primary Prevention

Brazil
Peking University
National Natural Science Foundation of China; Institute of reproductive and...

Completed

Effects of Low-dose Complex B-vitamins on Homocysteine and Framingham Risk Score Among Chinese Elderly

Hyperhomocysteinemia

China
Sussex NHS Research Consortium
University of Surrey; NHS Research and Development; Lab 21, Cambridge

Completed

Impact of a Gene Test for Susceptibility to Lung Cancer in Smokers

Smoking Cessation

United Kingdom
Hospices Civils de Lyon

Unknown

DARK STUDY "DysbetalipoproteinemiA and atheRoma Risk" (DARK)

Dysbetalipoproteinemia

France
Firalis SA

Recruiting

A Prospective, Monocentric Clinical Study for the Validation of in Vitro Diagnostic Tests Developed by Firalis (ApoDiag)

Genetic Health Risks

France
University of Haifa
Bnai Zion Medical Center; Clalit Health Services, Haifa and West Galilee

Not yet recruiting

Risk and Clinical Consequences of Low Count Monoclonal B-cell Lymphocytosis (LC MBL) (MBL RiskConseq)

Cardiovascular Diseases | Infections | Autoimmune Diseases | Parkinson Disease | Dementia | Alzheimer Disease | Chronic Lymphocytic Leukemia | Monoclonal B-Cell Lymphocytosis | Cancers
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Assesment the Efficacy of Dd-cfDNA in Routine Patient Care in Kidney Transplant Recipients" (AI-CARE)

Renal Transplantation

France
Hospital Nossa Senhora da Conceicao

Not yet recruiting

ARISCAT, ASA and LAS VEGAS Risk Scores and the Incidence of Postoperative Pulmonary Complications in Thoracic Surgery

Postoperative Complications
Vrinnevi Hospital
Ryhov Hospital

Recruiting

Impact of Inflammatory Indexes and Gene Scores in Prediction of Atrial Fibrillation Recurrence Following Electrical Cardioversion (IERV)

Inflammation | Atrial Fibrillation | Genetic Predisposition to Disease

Sweden
Children's Oncology Group

Not yet recruiting

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor | Stage IV Kidney Wilms Tumor
Samara State Medical University
Regional Samara Clinical Hospital n. a. V.D.Seredavin

Recruiting

Cardiovascular Risk Stratification on the Basis of Surface Enhanced Raman Spectroscopy (CRUISERS)

Coronary Atherosclerosis of Native Coronary Artery

Russian Federation

Search clinical trials for: Genetic risk score

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