Search clinical trials for: Glucokinase activator

Total 585 results

Hua Medicine Limited
Covance

Completed

Long-term Efficacy and Safety of HMS5552 add-on to Metformin in T2DM Subjects

Diabetes Mellitus, Type 2

China
Majianhua

Unknown

The Progress of Diabetes Mellitus After HMS5552 Treatment in Type 2 Diabetes Mellitus

Type2 Diabetes Mellitus

China
Hua Medicine Limited
Tigermed Consulting Co., Ltd

Completed

Long-term Efficacy and Safety of HMS5552 in T2DM Subjects

Diabetes Mellitus, Type 2

China
Array Biopharma, now a wholly owned subsidiary...

Completed

A Safety Study of ARRY-403 in Patients With Type 2 Diabetes

Type 2 Diabetes

United States
PegBio Co., Ltd.

Completed

Clinical Trial for the Investigational Drug (PB-201) in Subjects With Type 2 Diabetes Mellitus

Type2 Diabetes Mellitus

China
Yabao Pharmaceutical Group

Completed

Multiple Ascending Doses of Globalagliatin Hydrochloride in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus | Hyperglycaemia (Diabetic)

China
Eli Lilly and Company

Completed

A Study of LY2608204 in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Singapore, United States
Eli Lilly and Company

Completed

A Study to Compare Two Forms of LY2608204 in Healthy People

Healthy Volunteers

Singapore
Hua Medicine Limited

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HMS5552 in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus
vTv Therapeutics

Completed

Add Glucokinase Activator to Target A1c (AGATA)

Diabetes Mellitus, Type 2

United States
Hua Medicine Limited

Completed

Drug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DM

Type 2 Diabetes Mellitus

United States
Array BioPharma

Completed

A Safety Study of ARRY-403 in Patients With Type 2 Diabetes

Type 2 Diabetes

United States
Eli Lilly and Company

Terminated

A Study of LY2599506 in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Russian Federation, Puerto Rico, Spain, United States, Australia
Eli Lilly and Company

Terminated

A Study of LY2599506 (Oral Agent Medication: Glucokinase Activator 1) in Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Russian Federation, Spain, Germany, Australia, Austria, Israel, Czech Republic
The First Hospital of Jilin University

Not yet recruiting

The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy

Sepsis-induced Coagulopathy
Kafrelsheikh University

Recruiting

Predictors of Post-alteplase Hemorrhagic Transformation of Brain Infarction

Ischemic Stroke | Alteplase Adverse Reaction

Egypt
Second Affiliated Hospital of Nanchang University
Changhai Hospital

Recruiting

Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK)

Aneurysmal Subarachnoid Hemorrhage

China
Agios Pharmaceuticals, Inc.

Not yet recruiting

A Study of Mitapivat in Participants With Sickle Cell Disease and Nephropathy

Sickle Cell Disease | Nephropathy
The Second Hospital of Hebei Medical University

Recruiting

Treatment of Acute Ischemic Stroke With Rt-PA Combined With Edaravone Dexborneol (TASPE)

Acute Ischemic Stroke

China
Chinese University of Hong Kong
Queen Mary Hospital, Hong Kong; Princess Margaret Hospital, Canada; Tuen Mun... and other collaborators

Not yet recruiting

Intravenous Thrombolytic Therapy in Acute Ischemic Stroke Patients on DOAC (DOAC-IVT)

CVA (Cerebrovascular Accident)

Hong Kong
The University of Texas Health Science Center,...
Baszucki Brain Research Fund

Recruiting

A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression

Bipolar Depression

United States
Beijing Tiantan Hospital

Recruiting

Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events-5 (TRACE-5)

Ischemic Stroke, Acute

China
The First Affiliated Hospital of Zhengzhou University
Techpool Bio-Pharma Co., Ltd.

Recruiting

Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective Study

Acute Ischemic Stroke

China
Kristina Svennerholm
Karolinska University Hospital; Sunderby Hospital; University Hospital, Linkoeping and other collaborators

Recruiting

Mechanical Thrombectomy With the FlowTriever Device in Acute Pulmonary Embolism - a Retrospective Analysis

Pulmonary Embolism

Sweden
Second Affiliated Hospital, School of Medicine,...

Recruiting

ALteplase in Patients With LOW NIHSS and Specified Disabling Deficits (ALLOW)

Thrombosis

China
Jinling Hospital, China

Recruiting

Clinical Study of Bowel Preparation Before Colonoscopy

Bowel Preparation

China
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III... and other conditions
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai Fifth People's Hospital; Shanghai Deji... and other collaborators

Recruiting

Tenecteplase Thrombolytic Therapy for Acute Ischemic Stroke in China (TTT-AIS CHINA)

Ischemic Stroke

China
Shionogi

Recruiting

A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke (REvive)

Acute Ischemic Stroke

Japan, Israel, United States, Australia, Hong Kong
EuroBloodNet Association

Not yet recruiting

Safety and Efficacy of Mitapivat Sulfate in Adult Patients With Erythrocyte Membranopathies (SATISFY)

Hereditary Red Blood Cell Disorder (Disorder)

Denmark, Netherlands
ASST Fatebenefratelli Sacco
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; Careggi Hospital; University Hospital Tuebingen and other collaborators

Not yet recruiting

Clinical Phenotypes in Pericarditis: IL-1RA Antibodies and suPAR Levels (PERIPLO)

Pericarditis

Germany, Italy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Aspirin Combined With Clopidogrel Versus Intravenous Alteplase for Acute Minor Stroke (AGREE)

Ischemic Stroke

China
National University of Malaysia

Recruiting

Pleural Irrigation With Normal Saline Versus Intrapleural Fibrinolytic (PENTAD-FT)

Pleural Infection

Malaysia
Xuanwu Hospital, Beijing

Recruiting

Intra-arterial Thrombolysis After Successful Thrombectomy for Acute Ischemic Stroke in the Posterior Circulation (IAT-TOP)

Acute Ischemic Stroke | Arterial Thrombosis | Posterior Circulation Brain Infarction

China
Stimit AG

Recruiting

STIMIT Activator 1 IDE Pivotal Study

Diaphragm Issues

United States
Northwestern University
National Cancer Institute (NCI); Moleculin Biotech, Inc.

Not yet recruiting

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

MGMT-Unmethylated Glioblastoma | Glioblastoma, IDH-Wildtype

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Shenzhen Hospital of Southern Medical University

Recruiting

Intra-arterial Alteplase for Acute Ischemic Stroke After Mechanical Thrombectomy (PEARL)

Stroke, Acute Ischemic

China
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Cambridge; University of Newcastle Upon-Tyne and other collaborators

Recruiting

Pulmonary Hypertension: Intensification and Personalisation of Combination Rx (PHoenix)

Pulmonary Arterial Hypertension

United Kingdom
Hospital Clinic of Barcelona
Fundacion Clinic per a la Recerca Biomédica; Instituto de Salud Carlos III

Not yet recruiting

CHemical OptImization of Cerebral Embolectomy 2 (CHOICE 2). (CHOICE2)

Stroke, Acute | Stroke, Acute Ischemic

Spain
Mayo Clinic
AbbVie; Cedars-Sinai Medical Center; Ironwood Pharmaceuticals, Inc.

Not yet recruiting

A Study of Virtual Reality and Linaclotide for IBS-C (IBSC-VR)

Irritable Bowel Syndrome With Constipation

United States
Chinese University of Hong Kong

Not yet recruiting

Trial of Reduced Alteplase Dose for Parapneumonic Effusion (TRAPPE)

Pleural Infection

Hong Kong
Maastricht University

Recruiting

Networked Drug REpurposing for Mechanism-based neuroPrOtection in Acute Ischaemic STROKE (REPO-STROKE II)

Ischemic Stroke, Acute

Germany
AbbVie
Ironwood Pharmaceuticals, Inc.

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide

Functional Constipation

United States, Bulgaria, United Kingdom, Croatia, Germany, Hungary
Danish Headache Center

Not yet recruiting

Effect of Riocigaut on Migraine Attack Induction and Cerebral Vasodilation in Migraine Patients.

Migraine Without Aura

Denmark
Beijing Tiantan Hospital
Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd; The Place Pharmaceutical(Jiangsu)...

Recruiting

Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ）

Acute Ischemic Stroke

China
Tianjin Huanhu Hospital

Recruiting

MR Imaging Selection for Endovascular Treatment in Acute Ischemic Stroke at 6 to 24 Hours (MIELS)

Endovascular Thrombectomy

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Application of tPA in Suprachoroidal and Subretinal Hemorrhage

Ocular Trauma

China
Xinqiao Hospital of Chongqing
Zhejiang University

Recruiting

Intravenous Tirofiban Versus Alteplase Before Mechanical Thrombectomy in Stroke (ADJUVANT)

Stroke, Acute Ischemic

China
AbbVie
Ironwood Pharmaceuticals, Inc.

Recruiting

A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation

Functional Constipation (FC) | Chronic Idiopathic Constipation (CIC)

United States, United Kingdom, Bulgaria, Netherlands
Centre Hospitalier Sud Francilien

Recruiting

Early Recanalization After Intravenous Thrombolysis With Tenecteplase Versus Alteplase in Distal Vessel Occlusion Strokes (DISTAL-IVT)

Acute Distal Vessel Occlusion Stroke

France

Search clinical trials for: Glucokinase activator

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